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Glia, ISSN 0894-1491, 07/2017, Volume 65, Issue 7, pp. 1186 - 1200
Peripheral nerve myelination involves rapid production of tightly bound lipid layers requiring cholesterol biosynthesis and myelin protein expression, but also... 
collagen | myelination | ascorbic acid | peripheral nerve | Schwann cell | methylation | PERIPHERAL-NERVE REGENERATION | MARIE-TOOTH-DISEASE | DNA METHYLATION | MOUSE | TIME RT-PCR | MODEL | NEUROSCIENCES | SCHWANN-CELLS INVITRO | BASAL LAMINA | ASCORBIC-ACID TREATMENT | SHEATH THICKNESS | Peripheral Nerves - ultrastructure | Male | Ganglia, Spinal - cytology | Sodium-Coupled Vitamin C Transporters - deficiency | RNA, Messenger - metabolism | Demethylation | Peripheral Nerve Injuries - physiopathology | Time Factors | Female | Collagen - genetics | Sensory Receptor Cells - metabolism | Disease Models, Animal | Sensory Receptor Cells - pathology | Cells, Cultured | Sodium-Coupled Vitamin C Transporters - genetics | Mice, Transgenic | Peripheral Nerves - pathology | Collagen - metabolism | Rotarod Performance Test | Animals | Ascorbic Acid - pharmacology | Mice | Peripheral Nerve Injuries - genetics | Remyelination - genetics | Gait Disorders, Neurologic - etiology | Physiological aspects | Enzymes | Methylation | Collagen | Vitamin C | Ascorbic acid | Peripheral nerves | Biosynthesis | Dorsal root ganglia | Rodents | Nerves | DNA methylation | Extracellular matrix | CpG islands | Translocation | Nutrient deficiency | Myelin | Cultures | Protein biosynthesis | Cholesterol | Promoters | Myelination | Acids | Sodium | Transporter | In vitro methods and tests | Index Medicus
Journal Article
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 515 - 523
Mitochondrial dysfunction is elevated in very early stages of Alzheimer's disease and exacerbates oxidative stress, which contributes to disease pathology.... 
Oxidative stress | Mitochondria | Ascorbate | Alzheimer's disease | Energy production | ACID | OXIDATIVE DNA-DAMAGE | LIPID-PEROXIDATION | PROTEIN OXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MILD COGNITIVE IMPAIRMENT | FREE-RADICALS | CYTOCHROME-C | ENDOCRINOLOGY & METABOLISM | A-BETA | STRESS | BRAIN | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Adenosine Triphosphate - agonists | Male | Sodium-Coupled Vitamin C Transporters - deficiency | Membrane Potential, Mitochondrial - drug effects | Alzheimer Disease - pathology | Biological Transport | Adenosine Triphosphate - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Disease Models, Animal | Signal Transduction | Gene Expression Regulation | Sodium-Coupled Vitamin C Transporters - genetics | Alzheimer Disease - drug therapy | Presenilin-1 - genetics | Mice, Transgenic | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Mitochondria - pathology | Reactive Oxygen Species - antagonists & inhibitors | Amyloid beta-Protein Precursor - genetics | Animals | Oxygen Consumption - drug effects | Presenilin-1 - metabolism | Alzheimer Disease - metabolism | Ascorbic Acid - pharmacology | Heterozygote | Mice | Adenosine Diphosphate - metabolism | Mutation | Alzheimer Disease - genetics | Genetic engineering | Disease susceptibility | Amyloid beta-protein | Index Medicus
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2010, Volume 30, Issue 9, pp. 1751 - 1757
OBJECTIVE—To assess the role of combined deficiencies of vitamins C and E on the earliest stages of atherosclerosis (an inflammatory condition associated with... 
atherosclerosis | nutrition | antioxidants | genetically altered mice | CONTROLLED-TRIAL | OXIDATIVE STRESS | WALL | OXIDANT STRESS | MACROPHAGES | PREVENTION | ASCORBIC-ACID | LESIONS | DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | BLOOD | Apolipoproteins E - deficiency | Oxidative Stress | Atherosclerosis - genetics | Male | Ascorbic Acid Deficiency - metabolism | Aortic Diseases - metabolism | Vitamins - pharmacology | L-Gulonolactone Oxidase - genetics | Organic Anion Transporters, Sodium-Dependent - genetics | Brain - metabolism | Time Factors | Vitamin E Deficiency - drug therapy | Myocardium - metabolism | Disease Models, Animal | Atherosclerosis - pathology | Macrophages - pathology | Liver - metabolism | Atherosclerosis - metabolism | Disease Progression | Mice, Knockout | Aortic Diseases - genetics | Macrophages - metabolism | Ascorbic Acid - pharmacology | Mice | L-Gulonolactone Oxidase - deficiency | Vitamin E - pharmacology | Organic Anion Transporters, Sodium-Dependent - deficiency | Vitamins - metabolism | Ascorbic Acid Deficiency - complications | Ascorbic Acid - metabolism | Atherosclerosis - etiology | Vitamin E Deficiency - complications | Female | Aortic Diseases - pathology | Severity of Illness Index | Sodium-Coupled Vitamin C Transporters | Atherosclerosis - drug therapy | Mice, Inbred C57BL | Symporters - deficiency | Vitamin E Deficiency - metabolism | Aortic Diseases - drug therapy | Animals | Ascorbic Acid Deficiency - drug therapy | Apolipoproteins E - genetics | Symporters - genetics | Sex Factors | Vitamin E - metabolism | Lipid Peroxidation | Dietary Supplements | Aortic Diseases - etiology | Index Medicus
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 04/2015, Volume 6, Issue 4, pp. 570 - 581
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 2010, Volume 496, Issue 1, pp. 38 - 44
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2011, Volume 50, Issue 1, pp. 27 - 36
To test whether severe ascorbic acid deficiency in macrophages affects progression of early atherosclerosis, we used fetal liver cell transplantation to... 
Antioxidants | Ascorbic acid | Free radicals | Macrophages | Apolipoprotein E deficiency | Atherosclerosis | HYPOXIA-INDUCIBLE FACTOR | CONTROLLED-TRIAL | OXIDATIVE STRESS | OXIDANT STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | PERITONEAL-MACROPHAGES | VITAMIN-E-DEFICIENCY | BETA-CAROTENE | FOAM CELL-FORMATION | ENDOCRINOLOGY & METABOLISM | GLYCATION END-PRODUCTS | Symporters - physiology | Atherosclerosis - genetics | Macrophages, Peritoneal - pathology | Male | Ascorbic Acid Deficiency - metabolism | Ascorbic Acid - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Ascorbic Acid - adverse effects | Atherosclerosis - etiology | Organ Specificity - genetics | Time Factors | Ascorbic Acid Deficiency - genetics | Female | Genetic Predisposition to Disease - prevention & control | Sodium-Coupled Vitamin C Transporters | Atherosclerosis - pathology | Macrophages, Peritoneal - physiology | Mice, Inbred C57BL | Cells, Cultured | Organic Anion Transporters, Sodium-Dependent - physiology | Disease Progression | Symporters - metabolism | Mice, Knockout | Animals | Apolipoproteins E - genetics | Symporters - genetics | Mice | Ascorbic Acid Deficiency - pathology | Macrophages, Peritoneal - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Atherosclerosis - prevention & control | Index Medicus | atherosclerosis | apolipoprotein E deficiency | macrophages | ascorbic acid
Journal Article