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Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2016, Volume 152, Issue 1, pp. 68 - 74.e2
Gastroenterology and Hepatology | Pancreatic Adenocarcinoma | Somatic Rearrangement | Cancer Genetics | Sequencing | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Middle Aged | Transcriptome | Male | Pancreatic Neoplasms - genetics | MutS Homolog 2 Protein - genetics | DNA Mismatch Repair - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Mutational Analysis | MutL Protein Homolog 1 - genetics | Aged, 80 and over | Adult | Female | Aged | Mutation | Genome | Pancreatic cancer | Index Medicus | Abridged Index Medicus
Journal Article
Nature reviews. Immunology, ISSN 1474-1733, 08/2006, Volume 6, Issue 8, pp. 573 - 583
Life Sciences & Biomedicine | Immunology | Science & Technology | Animals | Histones - genetics | Cytidine Deaminase - genetics | Cytidine Deaminase - metabolism | Humans | Lymphoma, B-Cell - immunology | Enhancer Elements, Genetic - genetics | Models, Genetic | Histones - metabolism | Immunoglobulins - genetics | Lymphoma, B-Cell - genetics | Somatic Hypermutation, Immunoglobulin - genetics | Index Medicus
Journal Article
2010, ISBN 9780123813022, Volume 105, Issue C
Antibody Diversity | B-Lymphocytes - enzymology | Somatic Hypermutation, Immunoglobulin | Humans | Genes, Immunoglobulin | Animals | B-Lymphocytes - immunology | Deamination | Cytidine Deaminase - metabolism | DNA Repair | Deoxycytosine Nucleotides - metabolism | Mice | DNA Damage | Deoxyuracil Nucleotides - metabolism | Proteins | Immunology | Mutation | Cellular biology | Genomics | Index Medicus
Book Chapter
Nature (London), ISSN 0028-0836, 2014, Volume 509, Issue 7502, pp. 637 - 640
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Clone Cells - cytology | B-Lymphocytes - cytology | Cell Proliferation | Germinal Center - immunology | Antibody Affinity - immunology | Genes, Reporter - genetics | Male | Antigen Presentation - immunology | Clone Cells - metabolism | Clonal Selection, Antigen-Mediated - immunology | Animals | B-Lymphocytes - immunology | Time Factors | T-Lymphocytes, Helper-Inducer - immunology | S Phase | Clone Cells - immunology | T-Lymphocytes, Helper-Inducer - cytology | Antigens - immunology | Mice | Germinal Center - cytology | Somatic Hypermutation, Immunoglobulin - genetics | B-Lymphocytes - metabolism | Cell Movement | Physiological aspects | Research | T cells | Reproduction, Asexual | Health aspects | Proliferating cell nuclear antigen | Antigens | Mutation | Cellular biology | Rodents | Immune system | Index Medicus
Journal Article
Annual Review of Biochemistry, ISSN 0066-4154, 2007, Volume 76, Issue 1, pp. 1 - 22
Uracil excision | Class switch recombination | Immunoglobulin gene diversification | Activation-induced deaminase | Somatic Hypermutation, Immunoglobulin | Cytidine Deaminase - genetics | Humans | Antibodies | DNA - metabolism | MutS Homolog 2 Protein - metabolism | DNA - genetics | DNA-Binding Proteins - metabolism | Genes, Immunoglobulin | Animals | Recombination, Genetic | Cytidine Deaminase - metabolism | DNA Repair | Transcription, Genetic | Uracil - metabolism | DNA Damage | Mutation | Immunoglobulin Class Switching | Enzymes | Immunoglobulins | Biochemistry | Genes | Deoxyribonucleic acid--DNA | Index Medicus
Conference Proceeding
Annual review of immunology, ISSN 0732-0582, 2008, Volume 26, Issue 1, pp. 481 - 511
Antibody diversity | Error-prone repair | Base excision repair | Activation-induced cytidine deaminase (AID, aicda) | Germinal center | Mismatch repair | Animals | Germinal Center - metabolism | Somatic Hypermutation, Immunoglobulin | Cytidine Deaminase - metabolism | DNA Mismatch Repair | DNA Repair | Germinal Center - immunology | Humans | Immunoglobulin Variable Region - genetics | Models, Genetic | Index Medicus
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 2013, Volume 210, Issue 8, pp. 1501 - 1507
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Gene Expression | Somatic Hypermutation, Immunoglobulin | VDJ Exons | Cytidine Deaminase - genetics | Germinal Center - immunology | Regulatory Sequences, Nucleic Acid | Gene Expression Regulation | Mice, Knockout | Immunoglobulin kappa-Chains - genetics | Animals | B-Lymphocytes - immunology | Chromatin Immunoprecipitation | Cytidine Deaminase - metabolism | Immunoglobulin Variable Region - genetics | Transcription, Genetic | Mice | 3' Untranslated Regions | Germinal Center - cytology | B-Lymphocytes - metabolism | Immunoglobulin Heavy Chains - genetics | Index Medicus | Cytidine Deaminase | Immunoglobulin kappa-Chains | B-Lymphocytes | Life Sciences | Germinal Center | Immunoglobulin Heavy Chains | Immunoglobulin Variable Region | Brief Definitive Report
Journal Article
Cell (Cambridge), ISSN 0092-8674, 06/2016, Volume 166, Issue 1, pp. 77 - 87
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | HIV Antibodies - blood | HIV Infections - blood | Somatic Hypermutation, Immunoglobulin | Humans | Infant | Antibodies, Neutralizing - genetics | Epitopes | Leukocytes, Mononuclear | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Adult | HIV Antibodies - genetics | Viral antibodies | Medical colleges | Child development | Vaccination | Antibodies | Infants | HIV (Viruses) | Health aspects | Index Medicus
Journal Article
International journal of cancer, ISSN 0020-7136, 11/2019, Volume 145, Issue 10, pp. 2816 - 2826
avidity maturation | TCR | somatic hypermutation | cancer immunotherapy | adoptive cell transfer | Life Sciences & Biomedicine | Oncology | Science & Technology | Directed Molecular Evolution - methods | Immunotherapy, Adoptive - methods | Skin Neoplasms - immunology | Skin Neoplasms - therapy | Humans | Melanoma, Experimental - therapy | Peptides - immunology | Histocompatibility Antigen H-2D | Mice, Transgenic | Mutagenesis, Site-Directed - methods | gp100 Melanoma Antigen - immunology | Proof of Concept Study | Point Mutation | Animals | Melanoma, Experimental - immunology | HEK293 Cells | Cell Line, Tumor | Receptors, Antigen, T-Cell - immunology | Mice | Receptors, Antigen, T-Cell - genetics | T cells | Analysis | Antigens | Therapy | Directed evolution | Melanoma | Antibodies | Autoantigens | Lymphocytes T | Immunological tolerance | Adoptive transfer | Optimization | T-cell receptor | Somatic hypermutation | Lymphocytes B | Lymphocytes | Immunotherapy | Antigen (tumor-associated) | Avidity | Mutation | Genetic modification | Tumors | Index Medicus
Journal Article
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Full Text
Somatic Hypermutation and Class Switch Recombination in Msh6-/-Ung-/- Double-Knockout Mice
The Journal of immunology (1950), ISSN 0022-1767, 10/2006, Volume 177, Issue 8, pp. 5386 - 5392
Life Sciences & Biomedicine | Immunology | Science & Technology | DNA Glycosylases - deficiency | DNA-Binding Proteins - physiology | Animals | Somatic Hypermutation, Immunoglobulin | DNA Glycosylases - physiology | Cytidine Deaminase - metabolism | DNA Mismatch Repair | Base Pair Mismatch | Mice | Immunoglobulin Class Switching | DNA-Binding Proteins - deficiency | Mice, Knockout | Index Medicus | Abridged Index Medicus
Journal Article