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Genes and Development, ISSN 0890-9369, 02/2009, Volume 23, Issue 4, pp. 496 - 511
Rictor is a component of the target of rapamycin complex 2 (TORC2). While TORC2 has been implicated in insulin and other growth factor signaling pathways, the... 
AKT | Fat metabolism | C. Elegans | Life span | Insulin/IGF | NERVOUS-SYSTEM | C. elegans | AKT/PKB | life span | DEVELOPMENTAL BIOLOGY | AGE-1 PI3 KINASE | CELL BIOLOGY | INSULIN | RAPTOR | MTOR COMPLEX-2 | LONGEVITY | SIGNALING PATHWAY | insulin/IGF | GENETICS & HEREDITY | C-ELEGANS | fat metabolism | TRANSCRIPTION FACTOR | Caenorhabditis elegans Proteins - metabolism | Reproduction - physiology | Fixatives - metabolism | Intestines - metabolism | Adipose Tissue - metabolism | Caenorhabditis elegans - physiology | Immediate-Early Proteins - metabolism | Oxazines - metabolism | Oncogene Protein v-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Somatomedins - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Boron Compounds - metabolism | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Signal Transduction | Caenorhabditis elegans - genetics | Mutation - genetics | Feeding Behavior - physiology | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Diet | Caenorhabditis elegans Proteins - genetics | Longevity - physiology | Lipid Metabolism - physiology | Life spans (Biology) | Caenorhabditis elegans | Immune response | Physiological aspects | Genetic aspects | Rapamycin | Research | Index Medicus | insulin | IGF | Research Paper
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2012, Volume 367, Issue 2, pp. 187 - 196
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 4/2010, Volume 103, Issue 7, pp. 964 - 976
Journal Article
Cancer Causes & Control, ISSN 0957-5243, 6/2016, Volume 27, Issue 6, pp. 737 - 748
Experimental and observational data link insulin, insulin-like growth factor (IGF), and estrogens to endometrial tumorigenesis. However, there are limited data... 
Estrogen receptor | Public Health | Biomedicine | Hematology | Endometrial cancer | Cancer Research | Oncology | Insulin-like growth factor | Epidemiology | Insulin | Biomedicine general | Endometrium | MENSTRUAL-CYCLE | ESTROGEN-RECEPTORS | PROGESTERONE-RECEPTORS | PTEN EXPRESSION | POSTMENOPAUSAL ENDOMETRIUM | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ONCOLOGY | IMMUNOCYTOCHEMICAL ANALYSIS | GENE-EXPRESSION | BODY-MASS INDEX | GROWTH-FACTOR-I | ADIPOSE-TISSUE | Immunohistochemistry | Insulin-Like Growth Factor Binding Protein 3 - genetics | Diabetes Mellitus - genetics | Humans | Middle Aged | Endometrial Neoplasms - metabolism | Insulin-Like Growth Factor I - genetics | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Receptors, Progesterone - metabolism | Insulin-Like Growth Factor II - genetics | Endometrial Neoplasms - genetics | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Receptor, Insulin - genetics | Postmenopause | Adult | Estrogen Receptor alpha - metabolism | Female | Estrogens - metabolism | Parity | Real-Time Polymerase Chain Reaction | Endometrium - metabolism | Gene Expression | Gonadal Steroid Hormones - metabolism | Premenopause | Risk Factors | Diabetes Mellitus - metabolism | PTEN Phosphohydrolase - metabolism | Insulin-Like Growth Factor II - metabolism | Insulin-Like Growth Factor Binding Protein 1 - metabolism | Insulin - metabolism | Receptors, Somatomedin - metabolism | Receptors, Somatomedin - genetics | Receptor, Insulin - metabolism | Aged | Insulin-Like Growth Factor I - metabolism | Insulin-Like Growth Factor Binding Protein 1 - genetics | Receptors | Analysis | Estrogen | Influence | Hormones, Sex | Research | Carcinogenesis | Risk factors | Index Medicus | Original Paper
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 03/2014, Volume 5, Issue 1, pp. 3472 - 3472
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 41, pp. 16983 - 16998
Mitochondrial activity and metabolic reprogramming influence the phenotype of cancer cells and resistance to targeted therapy. We previously established that... 
OXIDATIVE-PHOSPHORYLATION | PYRIMIDINE NUCLEOTIDE CARRIER | mitochondria | BNIP3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | ALPHA | cell surface receptor | AUTOPHAGY | HYPOXIA | BREAST-CANCER | cancer therapy | mitophagy | THERAPY | insulin-like growth factor (IGF) | cell signaling | cancer biology | cell metabolism | drug resistance | ENERGY-METABOLISM | Mitochondrial Dynamics | Neoplasms - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Humans | Cell Survival - genetics | Insulin-Like Growth Factor I - genetics | Neoplasm Proteins - metabolism | MCF-7 Cells | Mitochondria - genetics | Neoplasms - genetics | Tumor Suppressor Proteins - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | NF-E2-Related Factor 2 - genetics | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Mitochondrial Degradation | Carrier Proteins - genetics | Carrier Proteins - metabolism | Receptors, Somatomedin - metabolism | NF-E2-Related Factor 2 - metabolism | Receptors, Somatomedin - genetics | Neoplasms - pathology | Insulin-Like Growth Factor I - metabolism | Index Medicus | Molecular Bases of Disease
Journal Article
PLoS Biology, ISSN 1544-9173, 2014, Volume 12, Issue 4, pp. e1001824 - e1001824
Sleep fragmentation, particularly reduced and interrupted night sleep, impairs the quality of life of older people. Strikingly similar declines in sleep... 
RAPAMYCIN | LIFE-SPAN | LONGEVITY | PROTEIN | AROUSAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | DOPAMINE | MECHANISMS | OCTOPAMINE | DURATION | WAKEFULNESS | TOR Serine-Threonine Kinases - metabolism | Inhibitor of Apoptosis Proteins - genetics | Dopamine - biosynthesis | Pyrrolidonecarboxylic Acid - analogs & derivatives | Drosophila Proteins - metabolism | Pyrrolidonecarboxylic Acid - metabolism | Octopamine - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Forkhead Transcription Factors - metabolism | Receptor, Insulin - genetics | Insect Hormones - metabolism | Aging | Female | Somatomedins - biosynthesis | Sleep - physiology | Dopamine - metabolism | Receptors, Dopamine - biosynthesis | Somatomedins - metabolism | Drosophila - genetics | Receptors, Glucagon - genetics | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Circadian Rhythm - genetics | Circadian Rhythm - physiology | Oligopeptides - metabolism | Sirolimus - pharmacology | Sleep Deprivation - metabolism | Insulin - metabolism | Animals | Somatomedins - genetics | Drosophila - metabolism | Drosophila Proteins - genetics | Index Medicus | Enzymes | Transcription factors | Dopamine | Nervous system | Insulin-like growth factors | RNA polymerase | Kinases | Autophagy | Generalized linear models | Quality of life | Proteins | Survival analysis | Insects | Older people | Rodents | Behavior | Laboratory animals | Mass spectrometry | Age
Journal Article
Journal Article
Journal Article