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International journal of pharmaceutical compounding, ISSN 1092-4221, 11/2018, Volume 22, Issue 6, p. 516
Journal Article
Drug Safety, ISSN 0114-5916, 6/2012, Volume 35, Issue 6, pp. 459 - 470
Journal Article
Journal Article
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2005, Volume 146, Issue 4, pp. 561 - 567
The utility of halothane‐anaesthetized guinea‐pigs as an in vivo model for predicting the clinical potential of a drug to induce QT interval prolongation was... 
corrected QT interval | QT prolongation | terfenadine | chromanol 293B | monophasic action potential | halothane | sotalol | guinea‐pigs | Corrected QT interval | Monophasic action potential | Halothane | Chromanol 293B | Guinea-pigs | Terfenadine | D-sotalol | 2ND-GENERATION ANTIHISTAMINES | CARDIAC REPOLARIZATION | POTASSIUM CHANNELS | MEMBRANE CURRENTS | VENTRICULAR MYOCYTES | ANTIARRHYTHMIC-DRUG | guinea-pigs | RECTIFIER K+ CURRENT | TORSADE-DE-POINTES | IN-VIVO | PHARMACOLOGY & PHARMACY | Long QT Syndrome - chemically induced | Male | Halothane - administration & dosage | Terfenadine - administration & dosage | Sotalol - adverse effects | Terfenadine - adverse effects | Chromans - pharmacology | Time Factors | Delayed Rectifier Potassium Channels - drug effects | Drug-Related Side Effects and Adverse Reactions | Histamine H1 Antagonists - administration & dosage | Adrenergic beta-Antagonists - adverse effects | Models, Animal | Chromans - administration & dosage | Pharmaceutical Preparations - administration & dosage | Action Potentials - drug effects | Adrenergic beta-Antagonists - administration & dosage | Potassium Channel Blockers - pharmacology | Halothane - pharmacology | Anesthetics, Inhalation - pharmacology | Drug Evaluation, Preclinical - methods | Reproducibility of Results | Guinea Pigs | Anesthetics, Inhalation - administration & dosage | Potassium Channel Blockers - administration & dosage | Electrocardiography - drug effects | Linear Models | Heart Conduction System - drug effects | Sulfonamides - pharmacology | Histamine H1 Antagonists - adverse effects | Sotalol - administration & dosage | Algorithms | Animals | Heart - drug effects | Sulfonamides - administration & dosage | Heart Ventricles - drug effects | Index Medicus | Papers
Journal Article
Journal Article
Heart Rhythm, ISSN 1547-5271, 2016, Volume 14, Issue 4, pp. 564 - 569
Journal Article
Journal of Cardiovascular Pharmacology and Therapeutics, ISSN 1074-2484, 6/2011, Volume 16, Issue 2, pp. 192 - 196
Introduction: There are few safe antiarrhythmics for ischemic heart disease. Whereas ranolazine is a promising late INa blocker with antiarrhythmic effects,... 
Ventricular tachycardia | Late sodium current inhibitor | Ischemia/reperfusion | Arrhythmias | Ranolazine | CARDIAC & CARDIOVASCULAR SYSTEMS | RAT | ANTIANGINAL AGENT | ischemia/reperfusion | SOTALOL | arrhythmias | ventricular tachycardia | CARDIOPLEGIA | late sodium current inhibitor | ranolazine | PHARMACOLOGY & PHARMACY | REPERFUSION VENTRICULAR-ARRHYTHMIAS | ISCHEMIA-REPERFUSION | Piperazines - administration & dosage | Lidocaine - pharmacology | Injections, Intravenous | Acetanilides - administration & dosage | Myocardial Reperfusion Injury - complications | Anti-Arrhythmia Agents - pharmacology | Ventricular Fibrillation - etiology | Enzyme Inhibitors - administration & dosage | Statistics, Nonparametric | Ventricular Fibrillation - physiopathology | Female | Myocardial Reperfusion Injury - drug therapy | Severity of Illness Index | Ventricular Fibrillation - prevention & control | Acetanilides - pharmacology | Enzyme Inhibitors - pharmacology | Tachycardia, Ventricular - etiology | Rats | Random Allocation | Tachycardia, Ventricular - prevention & control | Lidocaine - administration & dosage | Anti-Arrhythmia Agents - administration & dosage | Piperazines - pharmacology | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - physiopathology | Sotalol - administration & dosage | Tachycardia, Ventricular - physiopathology | Animals | Sotalol - pharmacology | Infusions, Intravenous | Sodium channels | Care and treatment | Arrhythmia | Physiological aspects | Myocardial ischemia | Dosage and administration | Research | Drug therapy | Health aspects | Index Medicus
Journal Article