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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 40, pp. E8498 - E8507
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2020, Volume 130, Issue 1, pp. 329 - 334
Novel approaches for adjunctive therapy are urgently needed for complicated infections and patients with compromised immunity. Necrotizing fasciitis (NF) is a... 
MEDICINE, RESEARCH & EXPERIMENTAL | SPEB | EXPRESSION | PEPTIDE | PROTEASE | Life Sciences | Microbiology and Parasitology | Innate immunity | Immunology | Bacteriology
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 04/2018, Volume 200, Issue 8
Streptococcus pyogenes (group A Streptococcus [ GAS]) causes a wide range of human infections. The pathogenesis of GAS infections is dependent on the temporal... 
PepO | Streptococcus pyogenes | Pathogenesis | SpeB | Endopeptidase | Virulence regulation | HOST | ROPB | MICROBIOLOGY | EVASION | FAMILY | pathogenesis | O PEPO | GROUP-A STREPTOCOCCUS | endopeptidase | IN-VIVO | DISEASE | GENE-EXPRESSION | virulence regulation | BINDING
Journal Article
Biological Chemistry, ISSN 1431-6730, 12/2011, Volume 392, Issue 12, pp. 1077 - 1088
Abstract Group A streptococcus (Streptococcus pyogenes) is an exclusively human pathogen that causes a wide spectrum of diseases ranging from pharyngitis, to... 
Human infection | Animal models | C10 cysteine proteinase | Proteolysis | Virulence | Streptopain | Immune evasion | SpeB | Streptococcal cysteine proteinase | Enzymes | Pathogens | Immunoglobulins | Immune response | Cytokines | Cysteine proteinase | Septic shock | Proteinase inhibitors | Reviews | Necrotizing fasciitis | Impetigo | Extracellular matrix | Pharyngitis | Chemokines | Index Medicus
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 10/2013, Volume 455, pp. 107 - 118
Journal Article
Journal of Medical Microbiology, ISSN 0022-2615, 09/2018, Volume 67, Issue 9, pp. 1391 - 1401
Purpose. Streptococcus pyogenes, a notorious human pathogen that is responsible for various invasive and non-invasive diseases, possesses multiple virulence... 
Fukugiside | Streptococcus pyogenes | Antibiofilm | SpeB | Cell surface hydrophobicity | INFECTIONS | LIPOTEICHOIC ACID | antibiofilm | MICROBIOLOGY | IDENTIFICATION | speB | GROUP-A STREPTOCOCCUS | cell surface hydrophobicity | IN-VIVO | GENES | RESISTANCE | BINDING | EXPRESSION | SURFACES | Index Medicus
Journal Article
Molecular microbiology, ISSN 0950-382X, 12/2011, Volume 82, Issue 6, pp. 1481 - 1495
S treptococcal p yrogenic e xotoxin B (SpeB) is an extracellular cysteine protease that is a critical virulence factor made by the major human pathogen group A... 
signal peptide | RopB | gene regulation | SpeB | Virulence
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 40, p. E8498
Successful pathogens use complex signaling mechanisms to monitor their environment and reprogram global gene expression during specific stages of infection.... 
Pathogens | Animal models | Peptides | Secretion | Pathogenesis | Genes | Virulence | Phase control | SpeB gene | Cysteine proteinase | Amino acids | Infections | Gene expression | Cytosol | Cell density | Signal transduction | Molecules | Signaling | Molecular modelling | Protease | Bacteria | Toxins | Deoxyribonucleic acid--DNA
Journal Article
Frontiers in microbiology, ISSN 1664-302X, 2016, Volume 7, p. 1935
CovR/CovS is an important two-component regulatory system in human pathogen group A (GAS). Epidemiological studies have shown that inactivation of the sensor... 
Journal Article
Infection and Immunity, ISSN 0019-9567, 06/2000, Volume 68, Issue 6, pp. 3523 - 3534
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
Humans | Antigens, Bacterial - genetics | Streptococcal Infections - genetics