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1. Full Text Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti‐IgE/IgE immune complexes
by Bundhoo, A and Paveglio, S and Rafti, E and Dhongade, A and Blumberg, R. S and Matson, A. P
Clinical & Experimental Allergy, ISSN 0954-7894, 06/2015, Volume 45, Issue 6, pp. 1085 - 1098
Summary Background The mechanism(s) responsible for acquisition of maternal antibody isotypes other than IgG are not fully understood. This uncertainty is a... 
mother | cord blood | IgG anti‐IgE | FcRn | allergy | placenta | infant | autoantibodies | immune complexes | Allergy | Autoantibodies | Placenta | Cord blood | IgG anti-IgE | Mother | Immune complexes | Infant | CELLS | ALLERGEN-SPECIFIC IGE | MOUSE | SERUM | IMMUNOLOGY | SENSITIZATION | I-RELATED RECEPTOR | ASTHMA | MONOCLONAL-ANTIBODIES | EPSILON-RI | Immunoglobulin G - blood | Humans | Receptors, Fc - metabolism | Hypersensitivity - immunology | Immunoglobulin E - blood | Antibodies, Anti-Idiotypic - metabolism | Histocompatibility Antigens Class I - metabolism | Immunoglobulin E - immunology | Hypersensitivity - metabolism | Immunoglobulin G - immunology | Adult | Female | Antigen-Antibody Complex - metabolism | Cell Line | Fetal Blood - immunology | Placenta - immunology | Immunoglobulin E - metabolism | Antibodies, Anti-Idiotypic - immunology | Protein Transport | Placenta - metabolism | Pregnancy | Animals | Protein Binding | Antigen-Antibody Complex - immunology | Immunoglobulin G - metabolism | Autoimmunity | Fc receptors | Immunoglobulins | Medical research | Immune system | Original
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2. Full Text Anti-infliximab IgE and non-IgE antibodies and induction of infusion-related severe anaphylactic reactions
by Vultaggio, A and Matucci, A and Nencini, F and Pratesi, S and Parronchi, P and Rossi, O and Romagnani, S and Maggi, E
Allergy, ISSN 0105-4538, 05/2010, Volume 65, Issue 5, pp. 657 - 661
To cite this article: Vultaggio A, Matucci A, Nencini F, Pratesi S, Parronchi P, Rossi O, Romagnani S, Maggi E. Anti-infliximab IgE and non-IgE antibodies and... 
drug-specific IgE and IgM | anaphylaxis | anti-infliximab antibodies | drug allergy | drug‐specific IgE and IgM | anti‐infliximab antibodies | Anti-infliximab antibodies | Drug-specific IgE and IgM | Anaphylaxis | Drug allergy | IMMUNOGENICITY | BIOLOGICAL AGENTS | ALLERGY | IMMUNOLOGY | Drug Hypersensitivity - blood | Skin Tests | Enzyme-Linked Immunosorbent Assay | Antibodies, Anti-Idiotypic - blood | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Anaphylaxis - blood | Antibodies, Anti-Idiotypic - immunology | Male | Immunoglobulin M - immunology | Immunoglobulin E - blood | Anti-Inflammatory Agents - adverse effects | Immunoglobulin E - immunology | Immunoglobulin M - blood | Infliximab | Anaphylaxis - chemically induced | Drug Hypersensitivity - immunology | Anaphylaxis - immunology | Adult | Female | Antigen-antibody reactions | Allergy | Rheumatoid factor | Biological products | Rheumatoid arthritis | Monoclonal antibodies | Immunoglobulin E | Allergic reaction | Enzyme-linked immunosorbent assay | Immunoglobulins | Allergies
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3. Full Text Total serum IgE level influences oral food challenge tests for IgE‐mediated food allergies
by Horimukai, K and Hayashi, K and Tsumura, Y and Nomura, I and Narita, M and Ohya, Y and Saito, H and Matsumoto, K
Allergy, ISSN 0105-4538, 03/2015, Volume 70, Issue 3, pp. 334 - 337
Probability curves predicting oral food challenge test (OFC) results based on specific IgE levels are widely used to prevent serious allergic reactions.... 
specific IgE | total IgE | food allergy | oral food challenge test | EGG | ALLERGY | IMMUNOLOGY | UTILITY | CHILDHOOD | Food - adverse effects | Humans | Child, Preschool | Food Hypersensitivity - blood | Infant | Male | Egg White - adverse effects | Immunoglobulin E - blood | Milk - adverse effects | Animals | Food Hypersensitivity - immunology | Immunoglobulin E - immunology | Cattle | Female | Child | Food Hypersensitivity - diagnosis | Immunoglobulin E | Food allergy | Diagnosis | Analysis | Food allergies | Diagnostic tests | Clinical outcomes
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4. Full Text The 1st step initiation essential for allergen‐specific IgE antibody production upon the 2nd step: Induction of non‐specific IgE+ small B cells containing secondly‐sensitized allergen‐specific ones in mice firstly‐sensitized with an allergen
by Hannya, Natsuki and Ogita‐Nakanishi, Hiromi and Kato, Ryuji and Ijiri, Yoshio and Hayashi, Tetsuya and Tanaka, Kazuhiko and Kawata, Ryo and Takenaka, Hiroshi and Kubota, Takahiro and Yoshida, Ryotaro
Microbiology and Immunology, ISSN 0385-5600, 02/2018, Volume 62, Issue 2, pp. 99 - 110
ABSTRACT There was a significant amount of non‐specific, but not of allergen (e.g., papain, mite feces and four kinds of pollen)‐specific, IgE antibodies (Abs)... 
allergen‐specific IgE antibody | allergen‐specific IgE+ cell | allergy initiation | allergen-specific IgE antibody | allergen-specific IgE | cell | allergen-specific IgE(+) cell | ACTIVATION | IMMUNOGLOBULIN | CD40 LIGAND | MICROBIOLOGY | PERIPHERAL-BLOOD | INTERLEUKIN-4 PRODUCTION | IMMUNOLOGY | HELPER T-CELLS | RHINITIS | CEDAR POLLEN | DIFFERENTIATION | ANTIGEN | Immunoglobulin E | Allergy | Allergens | Papain | B cells | Allergic reaction | Lymphatic system | Hypersensitivity | Antibodies | Injection | Cedar | Lymph nodes | Lymphocytes B | Mice | Pollen | Feces | Lymph
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5. Full Text Local IgE in non‐allergic rhinitis
by Campo, P and Rondón, C and Gould, H. J and Barrionuevo, E and Gevaert, P and Blanca, M
Clinical & Experimental Allergy, ISSN 0954-7894, 05/2015, Volume 45, Issue 5, pp. 872 - 881
Summary Local allergic rhinitis (LAR) is characterized by the presence of a nasal Th2 inflammatory response with local production of specific IgE antibodies... 
NONATOPIC INTRINSIC ASTHMATICS | ALLERGEN-SPECIFIC IGE | CLASS SWITCH RECOMBINATION | BRONCHIAL BIOPSIES | NASAL PROVOCATION TEST | ALLERGY | IL-5 MESSENGER-RNA | GRASS-POLLEN | IMMUNOLOGY | IDIOPATHIC RHINITIS | IMMUNOGLOBULIN-E | CHRONIC RHINOSINUSITIS | Rhinitis - immunology | Diagnosis, Differential | Prevalence | Rhinitis, Allergic - immunology | Humans | Rhinitis - diagnosis | Th2 Cells - immunology | Rhinitis, Allergic - diagnosis | Th2 Cells - metabolism | Nasal Provocation Tests | Phenotype | Immunoglobulin E - immunology | Rhinitis - therapy | Rhinitis - epidemiology | Rhinitis | Immunoglobulin E | Allergens | Drug therapy | Nose | Allergies
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6. Full Text The Human IgE Repertoire
by Gadermaier, Elisabeth and Levin, Mattias and Flicker, Sabine and Ohlin, Mats and Institutionen för Immunteknologi and Lund University and Department of Immunotechnology and Lunds universitet
International Archives of Allergy and Immunology, ISSN 1018-2438, 02/2014, Volume 163, Issue 2, pp. 77 - 91
IgE is a key mediator in allergic diseases. However, in strong contrast to other antibody isotypes, many details of the composition of the human IgE repertoire... 
Review | Phage display | Antigen-specific IgE | Antigen specificity | IgE epitopes | Monoclonal antibodies | Specific human IgE | Combinatorial antibody library | Genetic engineering | IgE antibody specificity | IgE repertoire | Epitopes | Basic/clinical immunology | DUST MITE ALLERGEN | PHAGE DISPLAY LIBRARIES | CLASS SWITCH RECOMBINATION | EFFECTOR CELL DEGRANULATION | GRASS-POLLEN ALLERGEN | IMMUNOLOGY | COMPLEMENTARITY-DETERMINING REGION-3 | BET V 1 | MEMORY B-CELLS | ALLERGY | PHL P 5 | HUMAN MONOCLONAL-ANTIBODIES | Immunotherapy - methods | Humans | Transcriptome | Hypersensitivity - immunology | Animals | B-Lymphocytes - immunology | Combinatorial Chemistry Techniques | Genetic Engineering | Immunoglobulin E - immunology | Allergens - immunology | Immunity, Humoral | Immunoglobulin E - genetics | Immunotherapy - trends | B-Lymphocyte Subsets - immunology | Hypersensitivity - genetics | Receptors, Antigen, B-Cell - genetics | High-Throughput Nucleotide Sequencing | Allergies | Cells | Basic | clinical immunology | Clinical Medicine | Lungmedicin och allergi | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Respiratory Medicine and Allergy
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7. Full Text IgE-mediated allergy to chlorhexidine
by Garvey, Lene Heise, MD and Krøigaard, Mogens, MD and Poulsen, Lars K., DMSc and Skov, Per Stahl, PhD and Mosbech, Holger, DMSc and Venemalm, Lennart, PhD and Degerbeck, Fredrik, MSc and Husum, Bent, DMSc
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2007, Volume 120, Issue 2, pp. 409 - 415
Background Investigations at the Danish Anesthesia Allergy Centre have included testing for allergy to chlorhexidine since 1999. Objective To investigate... 
Allergy and Immunology | intradermal testing | drug allergy | histamine release | allergy | Chlorhexidine | anaphylaxis | skin prick testing | specific IgE | anesthesia | ANTIBODIES | HAPTENIC DRUG CHLORHEXIDINE | DERMATITIS | IMMUNOLOGY | IMMEDIATE | DIGLUCONATE | chlorhexidine | TRYPTASE | HYPERSENSITIVITY | Drug Hypersensitivity - metabolism | Tryptases - blood | Humans | Middle Aged | Male | Chlorhexidine - immunology | Immunoglobulin E - blood | Histamine Release | Aged, 80 and over | Drug Hypersensitivity - diagnosis | Adult | Female | Hypotension - etiology | Retrospective Studies | Disinfectants - immunology | Hypersensitivity, Immediate - diagnosis | Drug Hypersensitivity - etiology | Skin Tests | Urologic Surgical Procedures | Disinfectants - adverse effects | Hypersensitivity, Immediate - etiology | Hypersensitivity, Immediate - metabolism | Drug Hypersensitivity - immunology | Aged | Chlorhexidine - adverse effects | Allergy | Allergic reaction | Studies | Health services | Heart surgery | Blood banks | Disinfection & disinfectants | Patients | Allergies | Skin cancer
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8. Full Text The production and regulation of IgE by the immune system
by Wu, Lawren C and Zarrin, Ali A
Nature Reviews Immunology, ISSN 1474-1733, 2014, Volume 14, Issue 4, pp. 247 - 259
IgE not only provides protective immunity against helminth parasites but can also mediate the type I hypersensitivity reactions that contribute to the... 
ALLERGEN-SPECIFIC IGE | ANTIBODY CLASS SWITCH | FC-EPSILON-RI | BONE-MARROW-TRANSPLANTATION | CIRCULAR DNA | HUMAN B-CELLS | CLASS-SWITCH RECOMBINATION | IMMUNOLOGY | SECRETING CELLS | PLASMA-CELLS | IMMUNOGLOBULIN-E | Immunologic Surveillance | Receptors, IgE - physiology | Immune System - physiology | Humans | Immunoglobulin E - biosynthesis | Mice, Transgenic | Hypersensitivity, Immediate - etiology | Models, Immunological | Animals | B-Lymphocytes - immunology | Immunoglobulin E - genetics | Hypersensitivity, Immediate - immunology | Immunologic Memory | Mice | Immunoglobulin E - physiology | Immunoglobulin Class Switching | Immunoglobulin E | Physiological research | Research | Properties | Immune system
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9. Full Text Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production
by Gauvreau, Gail M and Harris, Jeffrey M and Boulet, Louis-Philippe and Scheerens, Heleen and Fitzgerald, J. Mark and Putnam, Wendy S and Cockcroft, Donald W and Davis, Beth E and Leigh, Richard and Zheng, Yanan and Dahlén, Barbro and Wang, Yehong and Maciuca, Romeo and Mayers, Irvin and Liao, X. Charlene and Wu, Lawren C and Matthews, John G and O'Byrne, Paul M
Science Translational Medicine, ISSN 1946-6234, 07/2014, Volume 6, Issue 243, pp. 243ra85 - 243ra85
Elevated serum levels of both total and allergen-specific immunoglobulin E (IgE) correlate with atopic diseases such as allergic rhinitis and allergic asthma.... 
MEDICINE, RESEARCH & EXPERIMENTAL | MESSENGER-RNAS | ALLERGEN-SPECIFIC IGE | SENSITIZATION | ALTERNATIVE RNA | NATIONAL-HEALTH | MONOCLONAL-ANTIBODY | ASTHMA MORBIDITY | SECRETING CELLS | PLASMA-CELLS | IMMUNOGLOBULIN-E | CELL BIOLOGY | Epitopes - immunology | Humans | Immunoglobulin E - metabolism | Middle Aged | Antibodies, Anti-Idiotypic - immunology | Receptors, IgE - antagonists & inhibitors | Adult | Female | Male | Receptors, IgE - immunology | Antibodies, Anti-Idiotypic - therapeutic use
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10. Full Text Quantitative in vitro and in vivo models to assess human IgE B cell receptor crosslinking by IgE and EMPD IgE targeting antibodies
by Vigl, Benjamin and Salhat, Nina and Parth, Michela and Pankevych, Halyna and Mairhofer, Andreas and Bartl, Stefan and Smrzka, Oskar W
Journal of Immunological Methods, ISSN 0022-1759, 10/2017, Volume 449, pp. 28 - 36
Targeting plasma IgE by therapeutic mABs like Omalizumab (Xolair ) is current clinical practice for severe allergic conditions or other IgE related diseases... 
Migis (mIg isotype-specific sequence) | M1 | Membrane IgE | Receptor crosslinking | IgE + B cell | Human EMPD (Extracellular Membrane Proximal Domain) | Migis (mlg isotype-specific sequence) | BIOCHEMICAL RESEARCH METHODS | IMMUNOLOGY | IgE plus B cell | C-EPSILON-MX | STRATEGIES | MEMBRANE-PROXIMAL DOMAIN | ASTHMA | ALLERGIC DISEASES | BOUND IGE | ANTI-IGE | LYMPHOCYTES | Cross-Linking Reagents | Omalizumab - chemistry | Humans | Immunoglobulin E - biosynthesis | Immunoglobulin E - metabolism | Omalizumab - metabolism | Antibodies, Anti-Idiotypic - immunology | Receptors, Antigen, B-Cell - metabolism | Receptors, Antigen, B-Cell - immunology | Antibodies, Anti-Idiotypic - metabolism | Immunoglobulin E - chemistry | Animals | Immunoglobulin E - immunology | Anti-Allergic Agents - metabolism | Receptors, Antigen, B-Cell - chemistry | Anti-Allergic Agents - chemistry | Antibodies, Anti-Idiotypic - chemistry | Mice | Immunoglobulin E | Monoclonal antibodies | Crosslinked polymers | Models | B cells | Analysis
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