X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1046) 1046
spermidine - analogs & derivatives (784) 784
spermidine - metabolism (577) 577
humans (542) 542
biochemistry & molecular biology (520) 520
polyamines (518) 518
spermidine (511) 511
index medicus (498) 498
spermidine - pharmacology (405) 405
polyamines - metabolism (379) 379
rats (329) 329
spermidine - chemistry (316) 316
male (305) 305
mice (294) 294
kinetics (260) 260
putrescine - metabolism (246) 246
spermine - metabolism (239) 239
spermine (235) 235
microbiology (222) 222
metabolism (212) 212
spermine - pharmacology (211) 211
putrescine (206) 206
spermine - analogs & derivatives (204) 204
female (193) 193
glutathione - analogs & derivatives (188) 188
molecular sequence data (181) 181
ornithine decarboxylase (171) 171
polyamines - pharmacology (164) 164
polyamine (160) 160
growth (158) 158
pharmacology & pharmacy (155) 155
phylogeny (152) 152
putrescine - pharmacology (151) 151
structure-activity relationship (146) 146
sequence analysis, dna (145) 145
cell division - drug effects (144) 144
dna, bacterial - genetics (139) 139
rna, ribosomal, 16s - genetics (139) 139
bacterial typing techniques (138) 138
glutathione - metabolism (137) 137
ornithine decarboxylase - metabolism (134) 134
analogs (133) 133
oncology (132) 132
cell line (131) 131
base composition (129) 129
ornithine - analogs & derivatives (127) 127
chemistry, medicinal (125) 125
ornithine decarboxylase inhibitors (123) 123
eflornithine - pharmacology (116) 116
fatty acids - chemistry (116) 116
ornithine - pharmacology (115) 115
enzymes (114) 114
spermidine - biosynthesis (114) 114
spermidine - analysis (111) 111
cells (110) 110
research article (110) 110
tumor cells, cultured (110) 110
antineoplastic agents - pharmacology (108) 108
substrate specificity (108) 108
cell biology (107) 107
cells, cultured (105) 105
dna (103) 103
dose-response relationship, drug (103) 103
inhibition (102) 102
acetyltransferases - metabolism (101) 101
chromatography, high pressure liquid (101) 101
biosynthesis (99) 99
eflornithine (99) 99
amino acid sequence (97) 97
putrescine - analogs & derivatives (95) 95
cancer (93) 93
derivatives (93) 93
research (92) 92
vitamin k 2 - analogs & derivatives (91) 91
polyamines - chemistry (90) 90
enzyme inhibitors - pharmacology (89) 89
molecular structure (89) 89
time factors (89) 89
life sciences (87) 87
spermidine spermine n1-acetyltransferase (86) 86
spermidine/spermine n-1-acetyltransferase (86) 86
chemistry, organic (84) 84
apoptosis (83) 83
escherichia-coli (82) 82
physiological aspects (82) 82
identification (81) 81
hydrogen-ion concentration (80) 80
oxidoreductases acting on ch-nh group donors - metabolism (79) 79
crithidia-fasciculata (78) 78
vitamin k 2 - chemistry (78) 78
proteins (76) 76
rats, inbred strains (76) 76
bacteria (74) 74
s-adenosylmethionine decarboxylase (74) 74
analysis (73) 73
binding sites (73) 73
cricetinae (73) 73
expression (73) 73
trypanothione (72) 72
gene expression (71) 71
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2079) 2079
Russian (13) 13
Japanese (11) 11
French (4) 4
German (4) 4
Chinese (2) 2
Italian (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Organic and Biomolecular Chemistry, ISSN 1477-0520, 2019, Volume 17, Issue 4, pp. 867 - 875
The synthesis of new N-1,N-8-diacetylspermidine (DiAcSpd) analogues having a linker with desired functional groups in the methylene skeleton, which have been... 
CHEMISTRY, ORGANIC | CROSS-METATHESIS | PHASE | POLYAMINE ANALOGS | SPERMIDINE | EFFICIENT PROTOCOL
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2018, Volume 475, Issue 3, pp. 663 - 676
Replacing protium with deuterium is an efficient method to modulate drug metabolism. N-alkylated polyamine analogues are polyamine antimetabolites with proven... 
CELLS | POLYAMINE OXIDASE | BIS(BENZYL)POLYAMINE ANALOGS | ALPHA-METHYLPOLYAMINES | LIQUID-CHROMATOGRAPHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORS | DERIVATIVES | CANCER-THERAPY | DEUTERIUM | SPERMIDINE/SPERMINE N-1-ACETYLTRANSFERASE
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2013, Volume 21, Issue 15, pp. 4530 - 4540
Polyamines are small essential polycations involved in many biological processes. Enzymes of polyamine metabolism have been extensively studied and are... 
Enzyme inhibitor | Polyamine deacetylase | Metalloenzyme | Polyamine analogues | Spermidine - chemistry | Spermidine - chemical synthesis | Aminohydrolases - antagonists & inhibitors | Aminohydrolases - chemistry | Spermidine - analogs & derivatives | Polyamines - metabolism
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0159494
The effects of spermidine analogues [norspermidine (NSPD, 33), spermidine (SPD, 34), homospermidine (HSPD, 44) and aminopropylcadaverine (APCAD, 35)] on cell... 
RAT-LIVER | TRANSPORT-SYSTEM | STIMULATION | RNA | HOMOSPERMIDINE | MULTIDISCIPLINARY SCIENCES | PREFERENTIAL UPTAKE SYSTEM | POTD | IDENTIFICATION | PROTEIN-SYNTHESIS | BINDING | Cadaverine - analogs & derivatives | Carrier Proteins - biosynthesis | Escherichia coli - drug effects | Mutant Proteins - genetics | Spermidine - analogs & derivatives | Cadaverine - pharmacology | Polyamines - metabolism | Lipoproteins - biosynthesis | RNA, Bacterial - drug effects | Escherichia coli - genetics | Escherichia coli Proteins - biosynthesis | Spermidine - pharmacology | Escherichia coli - metabolism | RNA, Bacterial - genetics | Sigma Factor - biosynthesis | Cell Proliferation - drug effects | Escherichia coli - growth & development | Gene Expression Regulation, Bacterial | DNA-Binding Proteins - biosynthesis | Molecular Chaperones - biosynthesis | Cell proliferation | Gene mutations | Growth | Analysis | Escherichia coli | Protein biosynthesis | Genetic aspects | Polyamines | Fourier transforms | Phosphorylation | Transcription factors | Laboratories | Stimulation | mRNA | Ribonucleic acid--RNA | Chromatography | Circular dichroism | Proteins | Cell growth | E coli | Protein synthesis | Pharmacy | Spermidine | Dichroism | Bacteria | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | Ribonucleic acid | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 04/2016, Volume 30, Issue 4, pp. 305 - 321
Chagas disease is a parasitic infection caused by the protozoa Trypanosoma cruzi that affects about 6 million people in Latin America. Despite its sanitary... 
Chagas disease | Drug repositioning | Paroxetine | Trypanosomatids virtual screening | Triclabendazole | Polyamines | TRYPANOSOMA-CRUZI EPIMASTIGOTES | TARGET | VIVO | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHAGAS-DISEASE | TRYPANOCIDAL ACTIVITY | TOXICITY | MOLECULES | IN-VITRO | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | BIOPHYSICS | TRYPANOTHIONE SYNTHETASE | BIOLOGICAL EVALUATION | Thiophenes - therapeutic use | User-Computer Interface | Chagas Disease - parasitology | Amide Synthases - antagonists & inhibitors | Humans | Imidazoles - chemistry | Spermidine - analogs & derivatives | Spermidine - chemistry | Polyamines - therapeutic use | Amide Synthases - chemistry | Trypanosoma cruzi - pathogenicity | Nitroimidazoles - therapeutic use | Computer Simulation | Imidazoles - therapeutic use | Nitroimidazoles - chemistry | Glutathione - therapeutic use | Glutathione - analogs & derivatives | Polyamines - chemistry | Antiprotozoal Agents - chemistry | Drug Repositioning | Spermidine - therapeutic use | Chagas Disease - drug therapy | Trypanosoma cruzi - drug effects | Glutathione - chemistry | Thiophenes - chemistry | Drugs | Parasitic diseases | Ligases | Antidepressants | Analysis | Physiological aspects | Nucleic acids | Chagas' disease | Cell differentiation | Parasitic protozoa | Molecular structure | Computer aided design--CAD | Pharmaceutical sciences | Analogs | Uptakes | Databases | Medical services | Mathematical models | Assaying | Life Sciences
Journal Article
Journal Article