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Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 21, pp. 9683 - 9692
RNA viruses present an extraordinary threat to human health, given their sudden and unpredictable appearance, the potential for rapid spread among the human... 
DRUG | EFLORNITHINE | REPLICATION | VIROLOGY | ALPHA-DIFLUOROMETHYLORNITHINE | DEPLETION | INFECTION | TRANSLATION | MAMMALIAN-CELLS | RESPIRATORY SYNDROME CORONAVIRUS | SPERMIDINE | Zika Virus Infection - drug therapy | Acetyltransferases - metabolism | Ebolavirus - metabolism | Chikungunya virus - metabolism | Humans | Eflornithine - pharmacology | Ebolavirus - drug effects | Zika Virus Infection - virology | Disease Outbreaks | RNA Viruses - drug effects | Hemorrhagic Fever, Ebola - virology | Hemorrhagic Fever, Ebola - drug therapy | Spermine - analogs & derivatives | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Mice, Inbred C57BL | Chikungunya Fever - drug therapy | Zika Virus - drug effects | Chikungunya Fever - virology | Polyamines - metabolism | Chikungunya virus - drug effects | Animals | Spermine - pharmacology | Mice | Spermine/analogs & derivatives | Virus Replication/drug effects | Hemorrhagic Fever, Ebola/virology | Life Sciences | Zika Virus/drug effects | Immunology | Chikungunya virus/metabolism | Chikungunya Fever/drug therapy | Zika Virus Infection/drug therapy | Ebolavirus/drug effects | Acetyltransferases/metabolism | Chikungunya virus/drug effects | Eflornithine/pharmacology | Spermine/pharmacology | Polyamines/metabolism | Chikungunya Fever/virology | Hemorrhagic Fever, Ebola/drug therapy | Virology | Microbiology and Parasitology | Zika Virus Infection/virology | Ebolavirus/metabolism | Antiviral Agents/pharmacology | RNA Viruses/drug effects
Journal Article
Plant Molecular Biology, ISSN 0167-4412, 1/2013, Volume 81, Issue 1, pp. 27 - 40
Here, α-Amy2/54 gene expression was used as a molecular probe to investigate the interrelationship among nitric oxide (NO), cyclic GMP (cGMP), and heme... 
Life Sciences | Biochemistry, general | Plant Pathology | α - Amy2/54 gene expression | Nitric oxide | Heme oxygenase-1 | cGMP | Aleurone layers | Plant Sciences | Triticum aestivum | α-Amy2/54 gene expression | ARABIDOPSIS-THALIANA | SEED-GERMINATION | ADVENTITIOUS ROOTING PROCESS | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUANYLYL CYCLASE ACTIVITY | GIBBERELLIN-RESPONSE MUTANT | BARLEY ALEURONE | PLANT SCIENCES | PROGRAMMED CELL-DEATH | INHIBITS APOPTOSIS | alpha-Amy2/54 gene expression | ABSCISIC-ACID | Cyclic GMP - pharmacology | Heme Oxygenase-1 - metabolism | Gene Expression - drug effects | Nitric Oxide - pharmacology | Protoporphyrins - pharmacology | Guanylate Cyclase - antagonists & inhibitors | Nitroprusside - pharmacology | alpha-Amylases - genetics | Heme Oxygenase-1 - genetics | Carbon Monoxide - pharmacology | Cyclic GMP - analogs & derivatives | Plant Proteins - antagonists & inhibitors | Plant Proteins - metabolism | Nitric Oxide Donors - pharmacology | Triticum - enzymology | Aminoquinolines - pharmacology | Genes, Plant - drug effects | Spermine - analogs & derivatives | Signal Transduction | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | alpha-Amylases - metabolism | Heme Oxygenase-1 - antagonists & inhibitors | Triticum - genetics | Plant Proteins - genetics | Spermine - pharmacology | Benzoates - pharmacology | Gibberellins - pharmacology | Nitric Oxide - metabolism | Plant Growth Regulators - pharmacology | Triticum - drug effects
Journal Article
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 06/2012, Volume 90, Issue 6, pp. 1218 - 1229
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2015, Volume 172, Issue 13, pp. 3341 - 3352
Journal Article
International Journal of Neuropsychopharmacology, ISSN 1461-1457, 05/2014, Volume 17, Issue 8, pp. 1321 - 1326
Several lines of evidence indicate that ketamine has a rapid antidepressant-like effect in rodents and humans, but underlying mechanisms are unclear. In the... 
Ketamine | AMPA receptors | Serotonin | nicotinic acetylcholine receptors | Dorsal raphe nucleus | α 4 β 2 -nicotinic acetylcholine receptors | α 4 β 2-nicotinic acetylcholine receptors | Key words AMPA receptors | PSYCHIATRY | DORSAL RAPHE | MECHANISMS | NEUROSCIENCES | CLINICAL NEUROLOGY | alphabeta-nicotinic acetylcholine receptors | NUCLEUS | 5-HT NEURONAL-ACTIVITY | PHARMACOLOGY & PHARMACY | PROJECTIONS | BLOCKADE | Nicotinic Antagonists - administration & dosage | Dihydro-beta-Erythroidine - pharmacology | Male | Ketamine - antagonists & inhibitors | Nicotinic Antagonists - pharmacology | Ketamine - administration & dosage | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Prefrontal Cortex - drug effects | Injections, Subcutaneous | Antidepressive Agents - pharmacology | Receptors, AMPA - metabolism | Spermine - analogs & derivatives | Receptors, Nicotinic - metabolism | Microinjections | Quinoxalines - administration & dosage | Spermine - administration & dosage | Rats | Benzothiadiazines - pharmacology | Animals | Dorsal Raphe Nucleus - metabolism | Microdialysis | Spermine - pharmacology | Receptors, AMPA - agonists | Dorsal Raphe Nucleus - drug effects | Prefrontal Cortex - secretion | Antidepressive Agents - administration & dosage | Serotonin - secretion | Benzothiadiazines - administration & dosage | Ketamine - pharmacology | Dihydro-beta-Erythroidine - administration & dosage | Receptors, AMPA - antagonists & inhibitors
Journal Article
Cardiovascular Research, ISSN 0008-6363, 06/2007, Volume 74, Issue 3, pp. 515 - 525
Objective: C-type natriuretic peptide (CNP) has recently been suggested to represent an endothelium-derived hyperpolarising factor (EDHF) in the mammalian... 
Microcirculation | Natriuretic peptide | Vasodilation | Blood flow | Endothelium-derived hyperpolarising factor | CARDIAC & CARDIOVASCULAR SYSTEMS | vasodilation | POTASSIUM CHANNELS | DEPENDENT HYPERPOLARIZATION | natriuretic peptide | CA2+-ACTIVATED K+ CHANNEL | RAT MESENTERIC-ARTERY | microcirculation | G-PROTEIN | HEPATIC-ARTERY | endothelium-derived hyperpolarising factor | NITRIC-OXIDE | RESISTANCE VESSELS | FACTOR EDHF | blood flow | SMALL-CONDUCTANCE | Male | Receptors, Atrial Natriuretic Factor - antagonists & inhibitors | Quinoxalines - pharmacology | Aorta | Atrial Natriuretic Factor - pharmacology | Biological Factors - metabolism | Natriuretic Peptide, C-Type - pharmacology | Ouabain - pharmacology | Spermine - analogs & derivatives | Pyrazoles - pharmacology | Membrane Potentials - drug effects | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Receptors, Atrial Natriuretic Factor - metabolism | Rats | Barium - pharmacology | Potassium Channels - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Patch-Clamp Techniques | Animals | Spermine - pharmacology | Mesenteric Arteries | Vasodilation - drug effects | In Vitro Techniques | Oligopeptides - pharmacology | Peptides | endothelium-derived hyperpolarizing factor
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2011, Volume 301, Issue 3, pp. 587 - 600
Transient receptor potential (TRP) ankyrin 1 (TRPA1) is a Ca2+-permeant, nonselective cationic channel. It is predominantly expressed in the C afferent sensory... 
Transient receptor potential vanilloid 1 | Synaptic transmission | Patchclamp | COLD HYPERALGESIA | PROTEIN-KINASE-C | PHYSIOLOGY | ION-CHANNEL TRPA1 | GLUTAMATERGIC SYNAPTIC-TRANSMISSION | GENE-RELATED PEPTIDE | patch-clamp | transient receptor potential vanilloid 1 | SPINAL-CORD | SENSORY NEURONS | DIRECT PHOSPHORYLATION | CELL BIOLOGY | SUBSTANTIA-GELATINOSA NEURONS | COVALENT MODIFICATION | synaptic transmission | Hyperalgesia - chemically induced | Calcium - metabolism | Capsaicin - pharmacology | Nociception - physiology | Ganglia, Spinal - cytology | Nociceptive Pain - chemically induced | Calcium Channels - physiology | Protein Kinase C - metabolism | Oocytes - drug effects | Behavior, Animal - drug effects | Synaptic Transmission - drug effects | Ankyrins - agonists | Membrane Potentials - drug effects | Calcium - pharmacology | TRPC Cation Channels | Colforsin - pharmacology | Oocytes - metabolism | Rats | Rats, Sprague-Dawley | 1-Methyl-3-isobutylxanthine - pharmacology | Tachyphylaxis - physiology | Mice, Knockout | Nociceptive Pain - physiopathology | Spermine - pharmacology | Mice | Inhibitory Postsynaptic Potentials - drug effects | Electrophysiological Phenomena - drug effects | Hydrogen-Ion Concentration | Maleimides - pharmacology | Phorbol 12,13-Dibutyrate - pharmacology | Isocyanates - pharmacology | Miniature Postsynaptic Potentials - drug effects | Excitatory Postsynaptic Potentials - drug effects | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Trigeminal Caudal Nucleus - cytology | Neurons - physiology | Transient Receptor Potential Channels - physiology | Neurons - drug effects | Action Potentials - drug effects | Miniature Postsynaptic Potentials - physiology | Cyclic AMP-Dependent Protein Kinases - metabolism | Xenopus laevis | Electrophysiological Phenomena - physiology | Inhibitory Postsynaptic Potentials - physiology | Ankyrins - physiology | Allyl Compounds - pharmacology | Membrane Potentials - physiology | Mice, Inbred Strains | Transient Receptor Potential Channels - agonists | TRPV Cation Channels - genetics | Hyperalgesia - physiopathology | Action Potentials - physiology | Animals | TRPA1 Cation Channel | Ion Channel Gating - drug effects | Nociception | Neural transmission | Ion channels | Research | Properties | Nervous System Cell Biology
Journal Article
Journal Article
Human Gene Therapy, ISSN 1043-0342, 08/1996, Volume 7, Issue 12, pp. 1437 - 1446
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65806
Polyamines decrease the permeability of the outer membrane of Escherichia coli to fluoroquinolones and beta-lactams. In this study, we tested the effect of... 
MULTIDRUG EFFLUX PUMP | TUBERCULOSIS H37RV | SMEGMATIS | GENE | CHANNEL | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | PROTEIN EXPRESSION | OUTER-MEMBRANE PERMEABILITY | STARVATION | DIFFUSION | Porins - metabolism | Cadaverine - pharmacology | Mycobacterium tuberculosis - drug effects | Dose-Response Relationship, Drug | Mycobacterium bovis - drug effects | Putrescine - pharmacology | Culture Media - chemistry | Mycobacterium tuberculosis - metabolism | Mycobacterium bovis - genetics | Porins - genetics | Biological Transport, Active - drug effects | Fluoroquinolones - antagonists & inhibitors | Bacterial Proteins | Polyamines - pharmacology | beta-Lactams - pharmacology | Mycobacterium bovis - metabolism | Spermine - pharmacology | Cell Membrane Permeability - drug effects | Fluoroquinolones - pharmacology | Spermidine - pharmacology | Culture Media - pharmacology | Anti-Bacterial Agents - pharmacology | Mycobacterium bovis - growth & development | Gene Expression Regulation, Bacterial | Hydrogen-Ion Concentration | Mycobacterium tuberculosis - genetics | Mycobacterium tuberculosis - growth & development | Mycobacterium | Complications and side effects | Mycobacteria | Physiological aspects | Quinolone antibacterial agents | Genetic aspects | Dosage and administration | Research | Polyamines | Drug resistance | Quinolones | Fluoroquinolones | Membrane permeability | Putrescine | pH effects | Accumulation | Tropical diseases | Proteins | Replicating | E coli | Spermidine | Inhibition | Public health | Cadaverine | Medical research | Outer membrane proteins | BCG | Glycerol | Cultures | Permeability | Gene expression | Membrane proteins | Disease prevention | Tuberculosis | Spermine | Antibiotics | Ciprofloxacin
Journal Article