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Journal Article
Advanced Materials, ISSN 0935-9648, 11/2014, Volume 26, Issue 41, pp. 7043 - 7050
Journal Article
European Journal of Neurology, ISSN 1351-5101, 01/2018, Volume 25, Issue 1, pp. 142 - 147
Background and purposeTo establish and validate diagnostic criteria for adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) due to... 
alanyl‐transfer | diagnostic criteria | adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia | RNA | colony‐stimulating factor 1 receptor | leukoencephalopathy | pigmented orthochromatic leukodystrophy | hereditary diffuse leukoencephalopathy with spheroids | synthetase 2 | adult-onset leukoencephalopathy with axonal spheroids and pigmented glia | colony-stimulating factor 1 receptor | alanyl-transfer RNA synthetase 2 | HDLS | LEUKODYSTROPHY | NEUROSCIENCES | CLINICAL NEUROLOGY | Leukoencephalopathies - pathology | Diagnosis, Differential | Leukoencephalopathies - genetics | Reproducibility of Results | CADASIL - pathology | Neuroglia - pathology | Humans | Middle Aged | Spheroids, Cellular - pathology | Male | Tomography, X-Ray Computed | CADASIL - genetics | Young Adult | Magnetic Resonance Imaging | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Axons - pathology | Cognition Disorders - etiology | Leukoencephalopathies - diagnosis | Adolescent | CADASIL - diagnosis | Adult | Female | Receptor, Notch3 - genetics | Aged | Genetic aspects | Diagnosis | Ligases | Leukoencephalopathy | Analysis | Transfer RNA | Sensitivity | Macrophage colony-stimulating factor | Colony-stimulating factor | Diagnostic systems | Mutation | Criteria | Spheroids | Genetic screening | Index Medicus | Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) | pigmented orthochromatic leukodystrophy (POLD) | colony stimulating factor 1 receptor (CSF1R) | alanyl-transfer (t)RNA synthetase 2 (AARS2) | hereditary diffuse leukoencephalopathy with spheroids (HDLS)
Journal Article
AIP Conference Proceedings, ISSN 0094-243X, 11/2016, Volume 1786, Issue 1
Thermophoretic force acting on spheroids with an equivalent volume to a sphere with a 2.54 cm radius is measured and compared to a theoretical result based on... 
Prolate spheroids | Spheroids | Oblate spheroids
Journal Article
eLife, ISSN 2050-084X, 03/2015, Volume 2015, Issue 4, pp. 1 - 25
Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human... 
EXPRESSION PATTERNS | PROGENITOR CELLS | HUMAN AIRWAY EPITHELIUM | VENTRAL FOREGUT | BIOLOGY | BRANCHING MORPHOGENESIS | DEFINITIVE ENDODERM | EXTRACELLULAR-MATRIX | MOUSE LUNG | CLUSTER-ANALYSIS | BASAL-CELLS | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Humans | Gene Expression Profiling | Spheroids, Cellular - cytology | Lung - cytology | Cell Culture Techniques - methods | Cell Differentiation - genetics | Endoderm - cytology | Organoids - metabolism | Organoids - ultrastructure | Lung - metabolism | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Cell Line | Microscopy, Electron, Transmission | Reproducibility of Results | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Spheroids, Cellular - metabolism | Cells, Cultured | Organoids - cytology | Reverse Transcriptase Polymerase Chain Reaction | Endoderm - metabolism | Organogenesis | Pluripotent Stem Cells - metabolism | Microscopy, Confocal | Lung - embryology | Cluster analysis | Mesenchyme | Transcription | Developmental biology | Lung | Lung diseases | Fetuses | Embryo cells | Basal cells | Principal components analysis | Smooth muscle | Genomes | Epithelium | Ribonucleic acid--RNA | Spheroids | Children & youth | Respiratory tract | Hospitals | Organoids | Stem cells | Alveoli | Pluripotency | Foregut | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2012, Volume 164, Issue 1, pp. 95 - 102
We describe the evaluation of doxorubicin-loaded PEG–PE micelles targeting using an ovarian cancer cell spheroid model. Most ovarian cancer patients present at... 
Cancer cell spheroids | Targeting | Immunomicelles | Doxorubicin | SOLID TUMORS | MONOCLONAL-ANTIBODY | TUMOR-CELLS | DRUG-RESISTANCE | HUMAN BREAST-CANCER | POLYMERIC MICELLES | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | MULTICELLULAR SPHEROIDS | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | ANTITUMOR EFFICACY | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Humans | Ovarian Neoplasms - pathology | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Flow Cytometry | Micelles | Female | Ovarian Neoplasms - metabolism | Spheroids, Cellular - drug effects | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - administration & dosage | In Situ Nick-End Labeling | Cell Survival - drug effects | Antibodies, Monoclonal - pharmacology | Spheroids, Cellular - metabolism | Antibodies, Monoclonal - pharmacokinetics | Spheroids, Cellular - ultrastructure | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Doxorubicin - pharmacokinetics | Antibiotics, Antineoplastic - administration & dosage | Microscopy, Confocal | Antibodies, Monoclonal - administration & dosage | Cell Line, Tumor | Phosphatidylethanolamines - chemistry | Doxorubicin - pharmacology | Drugs | Anthracyclines | Drug delivery systems | Care and treatment | Analysis | Ovarian cancer | Cancer | Vehicles | Index Medicus | Life Sciences | targeting | doxorubicin | immunomicelles
Journal Article
Oncogene, ISSN 0950-9232, 8/2018, Volume 37, Issue 32, pp. 4372 - 4384
The RAS proteins are the most frequently mutated oncogenes in cancer, with highest frequency found in pancreatic, lung, and colon tumors. Moreover, the... 
Ras | Synthetic Lethal | Spheroid | Proscillaridin A
Journal Article
Journal Article