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1. Full Text A view on sphingolipids and disease
by Kolter, Thomas
Chemistry and physics of lipids, ISSN 0009-3084, 2011, Volume 164, Issue 6, pp. 590 - 606
Metabolic disease | Sphingolipidoses | Lipids | Sphingolipids | Gangliosides | Carbohydrate Sequence | Sphingolipidoses - chemically induced | Sphingolipidoses - pathology | Sphingolipids - biosynthesis | Sphingolipids - chemistry | Disease - genetics | Glycosphingolipids - biosynthesis | Humans | Molecular Sequence Data | Sphingolipids - metabolism | Sphingolipidoses - enzymology | Animals | Lysosomes - metabolism | Glycosphingolipids - metabolism | Sphingolipidoses - metabolism | Glycosphingolipids - chemistry | Drug resistance in microorganisms | Atherosclerosis | Index Medicus
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2. Full Text Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses
by Baixauli, Francesc and Acín-Pérez, Rebeca and Villarroya-Beltrí, Carolina and Mazzeo, Carla and Nuñez-Andrade, Norman and Gabandé-Rodriguez, Enrique and Ledesma, Maria Dolores and Blázquez, Alberto and Martin, Miguel Angel and Falcón-Pérez, Juan Manuel and Redondo, Juan Miguel and Enríquez, Jose Antonio and Mittelbrunn, Maria
Cell metabolism, ISSN 1550-4131, 09/2015, Volume 22, Issue 3, pp. 485 - 498
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Sphingolipidoses - pathology | Lysosomes - genetics | Mitochondria - immunology | Mitochondrial Proteins - genetics | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Cell Respiration | Lysosomal Storage Diseases - immunology | Mitochondria - genetics | T-Lymphocytes - metabolism | Gene Deletion | Lysosomes - pathology | Sphingolipidoses - immunology | T-Lymphocytes - pathology | Transcription Factors - immunology | DNA-Binding Proteins - immunology | CD4-Positive T-Lymphocytes - metabolism | Lysosomal Storage Diseases - genetics | Mitochondria - pathology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Lysosomal Storage Diseases - pathology | Sphingolipidoses - genetics | Animals | T-Lymphocytes - immunology | Mice | Immunity, Cellular | Lysosomes - immunology | Mitochondrial Proteins - immunology | Inflammation | Mitochondrial DNA | T cells | Cell differentiation | Analysis | Neurophysiology | Index Medicus | autophagy | lysosome storage disorder | inflammation | mitochondria | T cell differentiation | glycolysis | TFEB | TFAM | sphingomyelin | metabolism | fatty acid oxidation
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3. Full Text Dysregulation of autophagy as a common mechanism in lysosomal storage diseases
by Seranova, Elena and Connolly, Kyle J and Zatyka, Malgorzata and Rosenstock, Tatiana R and Barrett, Timothy and Tuxworth, Richard I and Sarkar, Sovan
Essays in biochemistry, ISSN 0071-1365, 12/2017, Volume 61, Issue 6, pp. 733 - 749
Animals | Lysosomes - metabolism | Humans | Lysosomal Storage Diseases - genetics | Lysosomal Storage Diseases - metabolism | Autophagy - physiology | Autophagy - genetics | Sphingolipidoses - metabolism | Index Medicus
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4. Full Text The sphingolipid salvage pathway in ceramide metabolism and signaling
by Kitatani, Kazuyuki and Idkowiak-Baldys, Jolanta and Hannun, Yusuf A
Cellular signalling, ISSN 0898-6568, 2008, Volume 20, Issue 6, pp. 1010 - 1018
Fumonisin B1 | Protein kinase C | Salvage pathway | Sphingosine | Ceramide | Sphingolipid | Ceramide signal | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Sphingolipids - metabolism | Animals | Ceramides - metabolism | Signal Transduction | Sphingolipidoses - enzymology | Sphingolipidoses - genetics | Physiological aspects | Enzymes | Lipids | Metabolites | RNA | Index Medicus | salvage pathway | ceramide | sphingolipid | fumonisin B1 | ceramide signal | sphingosine | protein kinase C
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5. Full Text Advances in Sphingolipidoses: CRISPR-Cas9 Editing as an Option for Modelling and Therapy
by Santos, Renato and Amaral, Olga
International journal of molecular sciences, ISSN 1422-0067, 12/2019, Volume 20, Issue 23, p. 5897
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Enzyme Replacement Therapy | Animals | Gaucher Disease - genetics | beta-Glucosidase - genetics | Humans | Gene Editing - methods | Gaucher Disease - therapy | CRISPR-Cas Systems - genetics | Sphingolipidoses - therapy | Sphingolipidoses - genetics | Disease Models, Animal | Index Medicus
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6. Full Text DNA Nanostructures as Smart Drug-Delivery Vehicles and Molecular Devices
by Linko, Veikko and Ora, Ari and Kostiainen, Mauri A
Trends in biotechnology (Regular ed.), ISSN 0167-7799, 2015, Volume 33, Issue 10, pp. 586 - 594
Internal Medicine | self-assembly | biocomputing | cell uptake | immunostimulation | biosensing | DNA nanotechnology | enzymatic payloads | DNA origami | drug delivery | Cell uptake | Self-assembly | Immunostimulation | Biocomputing | Drug delivery | Biosensing | Enzymatic payloads | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Sphingolipidoses - pathology | Drug Delivery Systems - instrumentation | Signal Transduction | Nanotechnology - methods | Humans | Nanotechnology - instrumentation | DNA - metabolism | Sphingolipidoses - therapy | Enzyme Replacement Therapy - methods | DNA - chemistry | Neoplasms - therapy | Base Pairing | Nanostructures - chemistry | Neoplasms - pathology | Nucleic Acid Conformation | Drug Delivery Systems - methods | Drugs | Drug delivery systems | DNA | Smart drugs and nutrients | Vehicles | Design | Proteins | Medical research | Ligands | Nanotechnology | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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7. Full Text Fluid levity of the cell: Role of membrane lipid architecture in genetic sphingolipidoses
by D'Auria, Ludovic and Bongarzone, Ernesto R
Journal of neuroscience research, ISSN 0360-4012, 11/2016, Volume 94, Issue 11, pp. 1019 - 1024
lipid rafts | psychosine | Krabbe's disease | fluidity | sphingolipids | neurodegeneration | caveolin | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Sphingolipidoses - pathology | Animals | Membrane Lipids - genetics | Humans | Membrane Fluidity - physiology | Membrane Lipids - deficiency | Sphingolipidoses - genetics | Sphingolipidoses | Physiological aspects | Lipids | Nervous system diseases | Index Medicus | Krabbe’s disease
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8. Recent advances and novel treatments for sphingolipidoses
by Arenz, Christoph
Future medicinal chemistry, ISSN 1756-8919, 09/2017, Volume 9, Issue 14, pp. 1685 - 1698
lysosomal storage diseases | enzyme replacement therapy | sphingolipids | Morbus Fabry | protein misfolding | substrate reduction therapy | pharmacological chaperones | Morbus Gaucher | sphingolipidoses | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Recombinant Proteins - therapeutic use | Sphingolipidoses - pathology | alpha-Galactosidase - genetics | Enzyme Replacement Therapy | alpha-Galactosidase - therapeutic use | Glucosylceramidase - genetics | Humans | Sphingolipids - metabolism | alpha-Galactosidase - metabolism | Glucosylceramidase - metabolism | Recombinant Proteins - biosynthesis | Sphingolipidoses - genetics | Recombinant Proteins - isolation & purification | Lysosomes - metabolism | Glucosylceramidase - therapeutic use | Enzymes - genetics | Fabry Disease - drug therapy | Enzymes - therapeutic use | Enzymes - metabolism | Gaucher Disease - drug therapy | Sphingolipidoses - drug therapy
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