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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 03/2015, Volume 23, Issue 5, p. 1011
Display Omitted 
Sphingosine
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 10/2014, Volume 63, p. 147
Journal Article
Cancer Cell, ISSN 1535-6108, 01/2013, Volume 23, Issue 1, pp. 107 - 120
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2012, Volume 444, Issue 1, pp. 79 - 88
Journal Article
Science, ISSN 0036-8075, 4/2007, Volume 316, Issue 5822, pp. 295 - 298
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2011, Volume 17, Issue 8, pp. 2484 - 2492
Journal Article
International Journal of Cancer, ISSN 0020-7136, 02/2013, Volume 132, Issue 3, pp. 605 - 616
Sphingosine kinase is an enzyme that catalyses the phosphorylation of sphingosine to form sphingosine 1‐phosphate. Sphingosine 1‐phosphate is a bioactive... 
c‐SRC | SRC family kinases | sphingosine kinase | disease‐specific survival and recurrence | nuclear factor kappa B | sphingosine 1‐phosphate | extracelluar signal regulated kinase | AKT | c‐RAF‐1 | sphingosine 1‐phosphate receptor | c-SRC | c-RAF-1 | disease-specific survival and recurrence | sphingosine 1-phosphate receptor | sphingosine 1-phosphate | AKT ACTIVATION | PHOSPHORYLATION | TAMOXIFEN | CELL-PROLIFERATION | SPHINGOLIPID METABOLISM | GROWTH-FACTOR RECEPTOR | REGULATED KINASE-1/2 | ONCOLOGY | SPHINGOSINE-1-PHOSPHATE | LYN KINASE | EXPRESSION | Lysophospholipids - metabolism | Phosphorylation | Receptors, Estrogen - metabolism | Prognosis | Humans | Middle Aged | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Biomarkers, Tumor | Breast Neoplasms - metabolism | Cell Nucleus - metabolism | Lysophospholipids - biosynthesis | src-Family Kinases - metabolism | Female | Cell Membrane - metabolism | Sphingosine - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptors, Lysosphingolipid - metabolism | Signal Transduction | Breast Neoplasms - drug therapy | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Breast Neoplasms - radiotherapy | Sphingosine - analogs & derivatives | Sphingosine - biosynthesis | Tamoxifen - therapeutic use | Aged | Care and treatment | Analysis | Estrogen | Sphingosine | Phenols | Development and progression | Breast cancer | Phosphotransferases | Cells | Cancer | Proteins | Biomarkers | Kinases | Tumors | Index Medicus
Journal Article
2012, Methods in molecular biology, ISBN 1617798002, Volume 874.
Web Resource
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7560, pp. 342 - 346
Lipid mediators influence immunity in myriad ways. For example, circulating sphingosine-1-phosphate (S1P) is a key regulator of lymphocyte egress(1,2).... 
SPHINGOSINE 1-PHOSPHATE RECEPTOR | PROGENITOR | S1P | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | APOLIPOPROTEIN-M | CHOLESTEROL EFFLUX | LYMPHOCYTE EGRESS | EXPRESSION | SERUM-LIPID PROFILES | BLOOD | Fingolimod Hydrochloride - pharmacology | Inflammation - pathology | Lysophospholipids - metabolism | Lymphopoiesis | Central Nervous System - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Lipoproteins, HDL - metabolism | Central Nervous System - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Central Nervous System - immunology | Apolipoproteins - deficiency | Apolipoproteins M | Inflammation - metabolism | Lysophospholipids - agonists | Lymphocytes - immunology | Apolipoproteins - genetics | Sphingosine - agonists | Female | Sphingosine - metabolism | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Lysosphingolipid - metabolism | Lymphocytes - metabolism | Cell Proliferation - genetics | Encephalomyelitis, Autoimmune, Experimental - pathology | Signal Transduction | Lymphoid Progenitor Cells - metabolism | Apolipoproteins - metabolism | Mice, Inbred C57BL | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Lymphocytes - cytology | Lymphoid Progenitor Cells - cytology | Lysophospholipids - blood | Blood-Brain Barrier - pathology | Lysophospholipids - genetics | Sphingosine - analogs & derivatives | Animals | Hematopoietic Stem Cells - cytology | Protein Binding | Sphingosine - blood | Sphingosine - genetics | Mice | Cell Movement | Spleen | Plasma | Lymphatic system | Lymphocytes | Bone marrow | Homeostasis | Physiology | Index Medicus
Journal Article
Cellular Signalling, ISSN 0898-6568, 10/2010, Volume 22, Issue 10, pp. 1536 - 1542
Sphingosine kinase 1 (SK1) is an enzyme that catalyses the phosphorylation of sphingosine to produce the bioactive lipid sphingosine 1-phosphate (S1P). We... 
Sphingosine 1-phosphate signalling | Sphingosine kinase 1 | Fingolimod | Cancer | Proteasome | Apoptosis | IMMUNOSUPPRESSIVE AGENT FTY720 | PROTEIN-COUPLED RECEPTORS | FUNCTIONAL-CHARACTERIZATION | SPHINGOSINE-1-PHOSPHATE RECEPTORS | MAMMALIAN-CELLS | CELL BIOLOGY | LYMPHOCYTIC-LEUKEMIA | IN-VITRO | MOLECULAR-CLONING | TUMOR-GROWTH | Vinyl Compounds - chemistry | Stereoisomerism | Humans | Drug Resistance, Neoplasm | Male | Vinyl Compounds - pharmacology | Breast Neoplasms - enzymology | Enzyme Inhibitors - chemistry | Female | Antineoplastic Agents - pharmacology | Muscle, Smooth, Vascular - drug effects | Propylene Glycols - pharmacology | Androgens - physiology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Fingolimod Hydrochloride | Antineoplastic Agents - chemistry | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Pulmonary Artery - cytology | Organophosphonates | Sphingosine - pharmacology | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Sphingosine - analogs & derivatives | Propylene Glycols - chemistry | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Proteasome Endopeptidase Complex - metabolism | Muscle, Smooth, Vascular - enzymology | Sphingosine - chemistry | Phosphates | Enzymes | Phosphatases | Pharmacy | Cancer cells | Sphingosine | Physiological aspects | Breast cancer | Prostate cancer | Smooth muscle | Index Medicus | Degradation | Receptors | Inhibitors | Breast | Kinases | Arteries | Sphingosine kinase
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2010, Volume 362, Issue 5, pp. 387 - 401
In this 24-month, randomized trial involving patients with relapsing–remitting multiple sclerosis, oral fingolimod reduced the rates of relapse and disability... 
IMMUNE | SPHINGOSINE 1-PHOSPHATE RECEPTORS | MEDICINE, GENERAL & INTERNAL | FTY720 | CENTRAL-NERVOUS-SYSTEM | PHASE-II EXTENSION | AGONISTS | Arrhythmias, Cardiac - chemically induced | Herpesviridae Infections - etiology | Sphingosine - adverse effects | Herpesviridae Infections - mortality | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Young Adult | Propylene Glycols - adverse effects | Sphingosine - administration & dosage | Propylene Glycols - therapeutic use | Adult | Female | Immunosuppressive Agents - administration & dosage | Disability Evaluation | Liver Function Tests | Multiple Sclerosis, Relapsing-Remitting - pathology | Macular Edema - chemically induced | Double-Blind Method | Administration, Oral | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Kaplan-Meier Estimate | Fingolimod Hydrochloride | Disease Progression | Magnetic Resonance Imaging | Sphingosine - analogs & derivatives | Propylene Glycols - administration & dosage | Adolescent | Brain - pathology | Immunosuppressive Agents - adverse effects | Sphingosine - therapeutic use | Multiple sclerosis | Usage | Magnetic resonance imaging | Placebos | Dosage and administration | Diagnosis | Drug therapy | Comparative analysis | Immunosuppressive agents | Interferon | Manuscripts | Index Medicus | Abridged Index Medicus
Journal Article