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Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 11/2015, Volume 407, Issue 28, pp. 8533 - 8542
Sphingosine 1-phosphate (S1P) is a signalling sphingolipid affecting multiple cellular functions of vascular and immune systems. It circulates at submicromolar... 
Biochemistry, general | Chemistry | Analytical Chemistry | Food Science | Sphingolipid | Characterization and Evaluation of Materials | Liquid chromatography | Laboratory Medicine | Apolipoprotein | Mass spectrometry | Environmental Monitoring/Analysis | CHEMISTRY, ANALYTICAL | BIOLOGICAL SAMPLES | BIOCHEMICAL RESEARCH METHODS | TANDEM MASS-SPECTROMETRY | LIQUID-CHROMATOGRAPHIC METHOD | QUANTITATIVE-ANALYSIS | LYSOPHOSPHATIDIC ACID | ERYTHROCYTES | INFLAMMATION | SPHINGOSINE-1-PHOSPHATE | BIOACTIVE SPHINGOLIPIDS | LIPOPROTEINS | Tandem Mass Spectrometry - standards | Blood Platelets - chemistry | Chromatography, Liquid - standards | Humans | Platelet Activation - physiology | Lysophospholipids - blood | Apolipoproteins M | Sphingosine - analogs & derivatives | Sphingosine - biosynthesis | Blood Platelets - metabolism | Plasma - chemistry | Lysophospholipids - biosynthesis | Lipoproteins, HDL - chemistry | Protein Binding | Sphingosine - blood | Apolipoproteins - chemistry | Blood Coagulation - physiology | Liquid-Liquid Extraction - methods | Chromatography, Liquid - methods | Lipocalins - chemistry | Serum Albumin - chemistry | Tandem Mass Spectrometry - methods | Serum - chemistry | Chemical properties | Research | Apolipoproteins | Analysis | Sphingosine | Correlation | Albumins | Methyl alcohol | Platelets | Sampling | Serums | Blood | Biological materials | Research Paper | Medical Biotechnology | Biomedical Laboratory Science/Technology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Biomedicinsk laboratorievetenskap/teknologi
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2012, Volume 55, Issue 11, pp. 5311 - 5325
Journal Article
Tetrahedron, ISSN 0040-4020, 2005, Volume 61, Issue 20, pp. 4715 - 4733
This review focuses on the bio- and chemical synthesis of sphingolipids, the cell surface receptor discoveries, and recent drug discovery effort targeting this... 
Lysophosphatidic acid | Sphingosine | Sphingosine-1-phosphate | PENARESIDIN-B | PROTEIN-KINASE-C | ASYMMETRIC-SYNTHESIS | DIASTEREOSELECTIVE SYNTHESIS | SPHINGOFUNGIN-F | D-ERYTHRO-SPHINGOSINE | L-SERINE | CHEMISTRY, ORGANIC | D-THREO-SPHINGOSINE | STEREOSELECTIVE-SYNTHESIS | COUPLED RECEPTOR EDG-1 | Lipids
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9613 - 9618
Protection of the endothelium is provided by circulating sphingosine-1-phosphate (S1P), which maintains vascular integrity. We show that HDL-associated S1P is... 
Receptors | Lipoproteins | Lungs | HDL lipoproteins | Lipids | Mice | Cholesterols | Endothelial cells | Endothelium | Crystal structure | Sphingolipids | Endothelial function | Vascular permeability | Atherosclerosis | endothelial function | atherosclerosis | EDG-1 | CELLS | CHOLESTEROL | sphingolipids | MULTIDISCIPLINARY SCIENCES | RECEPTOR | QUANTITATIVE-ANALYSIS | SPHINGOSINE 1-PHOSPHATE | PLASMA | crystal structure | vascular permeability | LIPOPROTEINS | BLOOD | Endothelium, Vascular - cytology | Lysophospholipids - metabolism | Humans | Lipoproteins, HDL - metabolism | Crystallography, X-Ray | Apolipoproteins M | Endocytosis | Apolipoproteins - genetics | Lipocalins - genetics | HEK293 Cells | Lipoproteins, HDL - chemistry | Sphingosine - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptors, Lysosphingolipid - metabolism | Lipocalins - metabolism | Protein Structure, Tertiary | Endothelial Cells - metabolism | Lysophospholipids - chemistry | Apolipoproteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Models, Molecular | Mice, Transgenic | Blotting, Western | Mice, Knockout | Sphingosine - analogs & derivatives | Animals | Endothelium, Vascular - metabolism | Protein Binding | Apolipoproteins - chemistry | Protein Conformation | Enzyme Activation | Lipocalins - chemistry | Sphingosine - chemistry | Mitogen-Activated Protein Kinases - metabolism | Biological Sciences | Medicinal Chemistry | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | permeability | Medicinska och farmaceutiska grundvetenskaper | vascular | Läkemedelskemi
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 09/2016, Volume 57, Issue 9, pp. 1737 - 1747
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2005, Volume 48, Issue 6, pp. 2036 - 2044
Journal Article