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1. Full Text Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
by Walls, Alexandra C and Xiong, Xiaoli and Park, Young-Jun and Tortorici, M. Alejandra and Snijder, Joost and Quispe, Joel and Cameroni, Elisabetta and Gopal, Robin and Dai, Mian and Lanzavecchia, Antonio and Zambon, Maria and Rey, Félix A and Corti, Davide and Veesler, David
Cell (Cambridge), ISSN 0092-8674, 02/2019, Volume 176, Issue 5, pp. 1026 - 1039.e15
glycoproteomics | spike glycoprotein | SARS-CoV | coronavirus | neutralizing antibodies | MERS-CoV | N-linked glycosylation | class I fusion protein | membrane fusion | Biochemistry, Genetics and Molecular Biology(all) | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | SARS Virus - immunology | Chlorocebus aethiops | Spike Glycoprotein, Coronavirus - metabolism | Immunity, Humoral - immunology | Receptors, Virus - metabolism | Humans | Molecular Mimicry - immunology | Coronavirus Infections - immunology | Middle East Respiratory Syndrome Coronavirus - immunology | SARS Virus - metabolism | Virus Internalization | Coronavirus - immunology | Middle East Respiratory Syndrome Coronavirus - metabolism | Spike Glycoprotein, Coronavirus - physiology | Antibodies, Neutralizing - immunology | Animals | Coronavirus - metabolism | HEK293 Cells | Protein Binding | Antibodies, Viral - immunology | Vero Cells | Antibodies, Monoclonal - immunology | Spike Glycoprotein, Coronavirus - ultrastructure | Viral antibodies | Respiratory tract infections | Analysis | Physiological aspects | Antibodies | Glycoproteins | Mass spectrometry | Health aspects | Index Medicus | Antibodies, Neutralizing | Coronavirus Infections | Antibodies, Monoclonal | Antibodies, Viral | Middle East Respiratory Syndrome Coronavirus | Spike Glycoprotein, Coronavirus | Life Sciences | SARS Virus | Molecular Mimicry | Coronavirus | Immunity, Humoral | Receptors, Virus
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2. Full Text SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
by Hoffmann, Markus and Kleine-Weber, Hannah and Schroeder, Simon and Krüger, Nadine and Herrler, Tanja and Erichsen, Sandra and Schiergens, Tobias S and Herrler, Georg and Wu, Nai-Huei and Nitsche, Andreas and Müller, Marcel A and Drosten, Christian and Pöhlmann, Stefan
Cell (Cambridge), ISSN 0092-8674, 04/2020, Volume 181, Issue 2, pp. 271 - 280.e8
COVID-19 | ACE2 | entry | priming | SARS-CoV-2 | neutralization | TMPRSS2 | coronavirus | spike | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Leucine - pharmacology | Pandemics | Receptors, Virus - metabolism | Coronavirus Infections - drug therapy | Humans | Pneumonia, Viral - drug therapy | Gabexate - pharmacology | Virus Internalization - drug effects | Protease Inhibitors - pharmacology | Ammonium Chloride - pharmacology | Antibodies, Neutralizing - immunology | Betacoronavirus - chemistry | Peptidyl-Dipeptidase A - metabolism | Vesiculovirus - genetics | SARS Virus - physiology | Leucine - analogs & derivatives | Coronavirus - physiology | Cell Line | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Gabexate - analogs & derivatives | Betacoronavirus - metabolism | Coronavirus Infections - immunology | Animals | Peptidyl-Dipeptidase A - chemistry | Receptors, Virus - chemistry | Coronavirus - chemistry | Coronavirus Infections - therapy | Coronavirus - genetics | Immunization, Passive | Antibodies, Viral - immunology | Serine Endopeptidases - metabolism | Drug Development | Betacoronavirus - genetics | Spike Glycoprotein, Coronavirus - chemistry | Viral antibodies | Medical research | Protease inhibitors | Proteases | World health | Resveratrol | Antibodies | Medicine, Experimental | Coronaviruses | Health aspects | Index Medicus
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3. Full Text Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26
by Wang, Qihui and Qi, Jianxun and Yuan, Yuan and Xuan, Yifang and Han, Pengcheng and Wan, Yuhua and Ji, Wei and Li, Yan and Wu, Ying and Wang, Jianwei and Iwamoto, Aikichi and Woo, Patrick C.Y and Yuen, Kwok-Yung and Yan, Jinghua and Lu, Guangwen and Gao, George F
Cell host & microbe, ISSN 1931-3128, 09/2014, Volume 16, Issue 3, pp. 328 - 337
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Chiroptera - virology | Coronavirus - classification | Dipeptidyl Peptidase 4 - metabolism | Receptors, Virus - metabolism | Humans | Molecular Sequence Data | Phylogeny | Receptors, Virus - genetics | Coronavirus Infections - metabolism | Coronavirus - metabolism | Coronavirus - isolation & purification | Amino Acid Sequence | Middle East Respiratory Syndrome Coronavirus - classification | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Coronavirus Infections - genetics | Dipeptidyl Peptidase 4 - genetics | Middle East Respiratory Syndrome Coronavirus - metabolism | Sequence Alignment | Animals | Receptors, Virus - chemistry | Coronavirus Infections - virology | Middle East Respiratory Syndrome Coronavirus - genetics | Coronavirus - genetics | Protein Binding | Spike Glycoprotein, Coronavirus - chemistry | Bats | Yuan (China) | Index Medicus
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4. Full Text Cross‐species transmission of the newly identified coronavirus 2019‐nCoV
by Ji, Wei and Wang, Wei and Zhao, Xiaofang and Zai, Junjie and Li, Xingguang
Journal of medical virology, ISSN 0146-6615, 04/2020, Volume 92, Issue 4, pp. 433 - 440
cross‐species transmission | phylogenetic analysis | recombination | 2019‐nCoV | codon usage bias | Life Sciences & Biomedicine | Science & Technology | Virology | Bungarus - genetics | Chiroptera - virology | Naja naja - virology | Bungarus - virology | Humans | Homologous Recombination | Phylogeny | Betacoronavirus - classification | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | SARS-CoV-2 | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Disease Outbreaks | Betacoronavirus - physiology | Snakes - virology | Disease Reservoirs | Naja naja - genetics | Genome, Viral | Spike Glycoprotein, Coronavirus - genetics | Codon Usage | Host Specificity | Zoonoses | Snakes - genetics | Animals | Coronavirus Infections - virology | Betacoronavirus - genetics | Chiroptera - genetics | Pneumonia, Viral - virology | Evolution, Molecular | Animal species | Bias | Homologous recombination | Seafood | Homology | Viruses | Genomes | Glycoproteins | Coronaviruses | Ribonucleic acid--RNA | Snakes | Cell surface | Gene sequencing | Disease transmission | Wildlife | Spike glycoprotein | Species | Index Medicus
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5. Full Text Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach
by Bhattacharya, Manojit and Sharma, Ashish R and Patra, Prasanta and Ghosh, Pratik and Sharma, Garima and Patra, Bidhan C and Lee, Sang‐Soo and Chakraborty, Chiranjib
Journal of medical virology, ISSN 0146-6615, 06/2020, Volume 92, Issue 6, pp. 618 - 631
epitopes | vaccine | immunoinformatics | SARS‐COV‐2 | Life Sciences & Biomedicine | Science & Technology | Virology | Betacoronavirus - pathogenicity | Toll-Like Receptor 5 - genetics | Epitopes, B-Lymphocyte - chemistry | Humans | Pandemics - prevention & control | Epitopes, T-Lymphocyte - genetics | Epitopes, B-Lymphocyte - immunology | Middle East Respiratory Syndrome Coronavirus - immunology | Betacoronavirus - immunology | COVID-19 | Epitopes - immunology | SARS-CoV-2 | Epitopes, B-Lymphocyte - genetics | Binding Sites | Amino Acid Sequence | Computational Biology - methods | Spike Glycoprotein, Coronavirus - genetics | Coronavirus Infections - immunology | SARS Virus - pathogenicity | Toll-Like Receptor 5 - immunology | Epitopes, T-Lymphocyte - chemistry | Histocompatibility Antigens Class II - immunology | Coronavirus Infections - virology | Middle East Respiratory Syndrome Coronavirus - genetics | COVID-19 Vaccines | Epitopes - chemistry | Molecular Docking Simulation | Betacoronavirus - genetics | Spike Glycoprotein, Coronavirus - chemistry | Coronavirus Infections - prevention & control | SARS Virus - immunology | SARS Virus - genetics | Spike Glycoprotein, Coronavirus - immunology | Protein Interaction Domains and Motifs | Epitopes, T-Lymphocyte - immunology | Protein Structure, Tertiary | Vaccines, Subunit | Histocompatibility Antigens Class I - immunology | Histocompatibility Antigens Class I - genetics | Histocompatibility Antigens Class II - chemistry | Epitopes - genetics | Histocompatibility Antigens Class I - chemistry | Toll-Like Receptor 5 - chemistry | Pneumonia, Viral - immunology | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Pneumonia, Viral - prevention & control | Viral Vaccines - chemistry | Protein Binding | Histocompatibility Antigens Class II - genetics | Pneumonia, Viral - virology | Viral Vaccines - immunology | Antigens | TLR5 protein | Peptides | Severe acute respiratory syndrome | Viral diseases | Glycoproteins | Coronaviruses | Vaccines | Epitopes | Major histocompatibility complex | Immunogenicity | Toll-like receptors | Spike glycoprotein | Index Medicus
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6. Full Text COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles’ heel conserved region to minimize probability of escape mutations and drug resistance
by Robson, B
Computers in biology and medicine, ISSN 0010-4825, 06/2020, Volume 121, pp. 103749 - 103749
COVID-19 | SARS-CoV-2 | Coronavirus | Peptidomimetic | Synthetic vaccine | Retroinverso | 2019-nCoV | Bionformatics | Q-UEL language | Wuhan seafood market coronavirus | Engineering | Computer Science, Interdisciplinary Applications | Life Sciences & Biomedicine | Technology | Engineering, Biomedical | Computer Science | Biology | Life Sciences & Biomedicine - Other Topics | Science & Technology | Mathematical & Computational Biology | Coronavirus Infections - prevention & control | Host Microbial Interactions - genetics | Coronavirus Infections - drug therapy | Humans | Pandemics - prevention & control | Pneumonia, Viral - drug therapy | Viral Vaccines - genetics | Vaccines, Synthetic - immunology | Betacoronavirus - immunology | Peptidyl-Dipeptidase A - genetics | Betacoronavirus - chemistry | Drug Design | Peptidyl-Dipeptidase A - metabolism | Spike Glycoprotein, Coronavirus - immunology | Host Microbial Interactions - immunology | Binding Sites | Amino Acid Sequence | Antiviral Agents - pharmacology | Peptidomimetics - pharmacology | Spike Glycoprotein, Coronavirus - genetics | Vaccines, Synthetic - genetics | Computational Biology | Coronavirus Infections - genetics | Models, Molecular | Coronavirus Infections - immunology | Coronavirus - immunology | Sequence Homology, Amino Acid | Angiotensin-Converting Enzyme 2 | Drug Resistance, Viral - genetics | Animals | Peptidyl-Dipeptidase A - chemistry | Coronavirus - chemistry | Coronavirus Infections - virology | Pneumonia, Viral - prevention & control | COVID-19 Vaccines | Coronavirus - genetics | Mutation | Betacoronavirus - genetics | Pneumonia, Viral - virology | Spike Glycoprotein, Coronavirus - chemistry | Viral Vaccines - immunology | Reptiles | Conformational analysis | Viral diseases | Viruses | Inflammatory response | Vaccines | Drug resistance | Dehydrogenase | Proteins | Prevention | Proteolysis | 11β-Hydroxysteroid dehydrogenase | Hydroxysteroids | Bioinformatics | Digestive tract | Medical research | Spike protein | Severe acute respiratory syndrome | Amino acid sequence | Common cold | Inflammation | Glycoproteins | Coronaviruses | Emodin | Severe acute respiratory syndrome coronavirus 2 | Computer applications | Spike glycoprotein | Binding sites | Index Medicus
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7. Full Text Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2
by Liu, Zhixin and Xiao, Xiao and Wei, Xiuli and Li, Jian and Yang, Jing and Tan, Huabing and Zhu, Jianyong and Zhang, Qiwei and Wu, Jianguo and Liu, Long
Journal of medical virology, ISSN 0146-6615, 06/2020, Volume 92, Issue 6, pp. 595 - 601
receptor‐binding domain (RBD) of coronavirus | SARS‐CoV‐2 spike protein (S) | SARS‐CoV‐2 | Coronavirus Disease 2019 (COVID‐19) | angiotensin‐converting enzyme 2 (ACE2) | Life Sciences & Biomedicine | Science & Technology | Virology | Betacoronavirus - pathogenicity | Chiroptera - virology | Pandemics | Receptors, Virus - metabolism | Humans | Phylogeny | Receptors, Virus - genetics | Betacoronavirus - classification | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | Peptidyl-Dipeptidase A - genetics | SARS-CoV-2 | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Snakes - virology | Peptidyl-Dipeptidase A - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Amino Acid Sequence | Protein Conformation, alpha-Helical | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Models, Molecular | China - epidemiology | Turtles - virology | Protein Interaction Mapping | Sequence Homology, Amino Acid | Angiotensin-Converting Enzyme 2 | Sequence Alignment | Animals | Peptidyl-Dipeptidase A - chemistry | Receptors, Virus - chemistry | Coronavirus Infections - virology | Protein Conformation, beta-Strand | Protein Binding | Spike Glycoprotein, Coronavirus - classification | Betacoronavirus - genetics | Eutheria - virology | Pneumonia, Viral - virology | Spike Glycoprotein, Coronavirus - chemistry | Binding | Epidemics | Aquatic reptiles | Divergence | Spike protein | Severe acute respiratory syndrome | Viral diseases | Transmission | Amino acids | Coronaviruses | Proteins | Receptors | Disease transmission | Respiratory diseases | Angiotensin | Turtles | Fatalities | Index Medicus
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8. Full Text Return of the Coronavirus: 2019-nCoV
by Gralinski, Lisa E and Menachery, Vineet D
Viruses, ISSN 1999-4915, 02/2020, Volume 12, Issue 2, p. 135
Life Sciences & Biomedicine | Science & Technology | Virology | Severe Acute Respiratory Syndrome - epidemiology | Severe Acute Respiratory Syndrome - virology | Social Media | Humans | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | SARS-CoV-2 | SARS Virus - genetics | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Disease Outbreaks | China | Disease Reservoirs | Communicable Diseases, Emerging | Genome, Viral | Disease Susceptibility | Spike Glycoprotein, Coronavirus - metabolism | Betacoronavirus - isolation & purification | Nucleocapsid Proteins - chemistry | SARS Virus - chemistry | Zoonoses | Animals | Coronavirus Infections - virology | Betacoronavirus - genetics | Pneumonia, Viral - virology | Spike Glycoprotein, Coronavirus - chemistry | Index Medicus | novel cov | wuhan | emerging viruses | wuhan pneumonia | coronavirus | 2019-ncov | sars-cov | mers-cov
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9. Full Text Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
by Paul A. Rota and M. Steven Oberste and Stephan S. Monroe and W. Allan Nix and Ray Campagnoli and Joseph P. Icenogle and Silvia Peñaranda and Bettina Bankamp and Kaija Maher and Min-hsin Chen and Suxiong Tong and Azaibi Tamin and Luis Lowe and Michael Frace and Joseph L. DeRisi and Qi Chen and David Wang and Dean D. Erdman and Teresa C. T. Peret and Cara Burns and Thomas G. Ksiazek and Pierre E. Rollin and Anthony Sanchez and Stephanie Liffick and Brian Holloway and Josef Limor and Karen McCaustland and Melissa Olsen-Rasmussen and Ron Fouchier and Stephan Günther and Albert D. M. E. Osterhaus and Christian Drosten and Mark A. Pallansch and Larry J. Anderson and William J. Bellini
Science (American Association for the Advancement of Science), ISSN 0036-8075, 5/2003, Volume 300, Issue 5624, pp. 1394 - 1399
Proteins | Coronavirus | Messenger RNA | RNA | Genomics | Viruses | Amino acids | Genomes | Research Articles | Open reading frames | SARS virus | SARS Virus/chemistry/classification/genetics/isolation & purification | Genome, Viral | Amino Acid Sequence | Nucleocapsid Proteins/chemistry/genetics | Humans | Membrane Glycoproteins/chemistry/genetics | Open Reading Frames | RNA, Viral/genetics | Regulatory Sequences, Nucleic Acid | Molecular Sequence Data | RNA, Messenger/genetics/metabolism | Viral Matrix Proteins/chemistry/genetics | Coronavirus/classification/genetics | Viral Envelope Proteins/chemistry/genetics | RNA Replicase/chemistry/genetics | Severe Acute Respiratory Syndrome/virology | Endopeptidases/chemistry/genetics | Phylogeny | Sequence Analysis, DNA | Conserved Sequence | Polyproteins/chemistry/genetics | Transcription, Genetic | Viral Proteins/chemistry/genetics | DNA, Complementary | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics | Microbiology | Virology | Coronavirus - classification | Viral Matrix Proteins - genetics | Severe Acute Respiratory Syndrome - virology | Membrane Glycoproteins - chemistry | RNA, Messenger - metabolism | SARS Virus - classification | Endopeptidases - chemistry | RNA, Viral - genetics | SARS Virus - genetics | SARS Virus - isolation & purification | Viral Envelope Proteins - genetics | RNA Replicase - genetics | Viral Proteins - chemistry | RNA, Messenger - genetics | Polyproteins - chemistry | Viral Proteins - genetics | Nucleocapsid Proteins - chemistry | Polyproteins - genetics | SARS Virus - chemistry | Membrane Glycoproteins - genetics | Spike Glycoprotein, Coronavirus | Endopeptidases - genetics | Nucleocapsid Proteins - genetics | Viral Matrix Proteins - chemistry | RNA Replicase - chemistry | Viral Envelope Proteins - chemistry | Coronavirus - genetics | Epidemics | Control | Hong Kong | DNA | Severe acute respiratory syndrome | China | Causes of | Development and progression | Coronaviruses | Research | Observations | Index Medicus
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