Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (31) 31
index medicus (29) 29
humans (20) 20
spike protein (19) 19
virology (19) 19
spike glycoprotein, coronavirus (17) 17
viruses (17) 17
mouse hepatitis-virus (13) 13
viral envelope proteins - metabolism (12) 12
coronavirus (11) 11
membrane fusion (11) 11
molecular sequence data (10) 10
spike glycoprotein, coronavirus - chemistry (10) 10
spike glycoprotein, coronavirus - ultrastructure (10) 10
viral envelope proteins - genetics (10) 10
acute respiratory syndrome (9) 9
article (9) 9
cell line (9) 9
crystal-structure (9) 9
membrane glycoproteins - metabolism (9) 9
microbiology (9) 9
protein binding (9) 9
respiratory syndrome coronavirus (9) 9
coronavirus infections - virology (8) 8
cryoelectron microscopy (8) 8
microscopy, electron (8) 8
models, molecular (8) 8
proteins (8) 8
receptors, virus - metabolism (8) 8
spike glycoprotein, coronavirus - metabolism (8) 8
virus internalization (8) 8
sars-coronavirus (7) 7
virus (7) 7
amino acid sequence (6) 6
analysis (6) 6
biochemistry & molecular biology (6) 6
cell biology (6) 6
coronavirus infections - veterinary (6) 6
coronaviruses (6) 6
health aspects (6) 6
multidisciplinary sciences (6) 6
protein multimerization (6) 6
spike glycoprotein (6) 6
viral envelope proteins - ultrastructure (6) 6
virion - ultrastructure (6) 6
base sequence (5) 5
cercopithecus aethiops (5) 5
coronavirus - ultrastructure (5) 5
glycoprotein (5) 5
glycoproteins (5) 5
membrane glycoproteins - genetics (5) 5
membrane-fusion (5) 5
mice (5) 5
protein conformation (5) 5
protein structure, tertiary (5) 5
receptor-binding domain (5) 5
sars coronavirus (5) 5
sars virus - metabolism (5) 5
sars virus - physiology (5) 5
sars virus - ultrastructure (5) 5
sars-cov (5) 5
spike glycoprotein, coronavirus - genetics (5) 5
vero cells (5) 5
veterinary sciences (5) 5
viral envelope proteins - chemistry (5) 5
virus diseases (5) 5
angiotensin-converting enzyme-2 (4) 4
coronavirus spike protein (4) 4
endocytosis (4) 4
feline infectious peritonitis (4) 4
functional receptor (4) 4
infectious diseases (4) 4
life sciences (4) 4
membrane glycoproteins - ultrastructure (4) 4
middle east respiratory syndrome coronavirus - ultrastructure (4) 4
murine coronavirus (4) 4
phylogeny (4) 4
proteolysis (4) 4
replication (4) 4
respiratory diseases (4) 4
sequence (4) 4
sequence homology, amino acid (4) 4
structure and assembly (4) 4
swine (4) 4
transmissible gastroenteritis coronavirus (4) 4
virion - metabolism (4) 4
[chim.cris]chemical sciences/cristallography (3) 3
antibodies (3) 3
antibodies, neutralizing - immunology (3) 3
antiviral agents - pharmacology (3) 3
biotechnology & applied microbiology (3) 3
bronchitis (3) 3
cell membrane - metabolism (3) 3
cell membrane - virology (3) 3
cells (3) 3
chemical sciences (3) 3
chickens (3) 3
china - epidemiology (3) 3
coronavirus infections - immunology (3) 3
cristallography (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer
by Walls, Alexana C and Tortorici, M Alejana and Bosch, Berend-Jan and Frenz, Brandon and Rottier, Peter J M and DiMaio, Frank and Rey, Félix A and Veesler, David
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 114 - 117
The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. Entry of... 
electron microscopy | antibodies | viral vaccines | Coronavirus spike glycoprotein | MURINE CORONAVIRUS | MEMBRANE-FUSION | ELECTRON CRYOMICROSCOPY | PARTICLE CRYO-EM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | FUSION PROTEIN | EM STRUCTURE DETERMINATION | HUMAN RECEPTOR | S2 DOMAIN | RESPIRATORY SYNDROME CORONAVIRUS | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Protein Multimerization | Models, Molecular | Molecular Sequence Data | Coronavirus Infections - immunology | Virus Internalization | Cryoelectron Microscopy | Murine hepatitis virus - immunology | Antibodies, Neutralizing - immunology | Murine hepatitis virus - chemistry | Animals | Coronavirus Infections - virology | Viral Vaccines - chemistry | Spike Glycoprotein, Coronavirus - immunology | Mice | Drosophila melanogaster | Spike Glycoprotein, Coronavirus - chemistry | Viral Vaccines - immunology | Murine hepatitis virus - ultrastructure | Spike Glycoprotein, Coronavirus - ultrastructure | Physiological aspects | Glycoproteins | Coronaviruses | Electron microscopy | Structure | Methods | Immunoglobulins | Peptides | Microscopy | Respiratory diseases | Viruses | Biochemistry | Cristallography | Chemical Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy
by Walls, Alexana C and Tortorici, M Alejana and Frenz, Brandon and Snijder, Joost and Li, Wentao and Rey, Félix A and DiMaio, Frank and Bosch, Berend-Jan and Veesler, David
Nature Structural and Molecular Biology, ISSN 1545-9993, 10/2016, Volume 23, Issue 10, pp. 899 - 905
The threat of a major coronavirus pandemic urges the development of strategies to combat these pathogens. Human coronavirus NL63 (HCoV-NL63) is an... 
Glycoproteins | Immunology | Cryoelectron microscopy | Viral membrane fusion | NEUTRALIZING ANTIBODY | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SARS CORONAVIRUS | BINDING DOMAIN | ENVELOPE GLYCOPROTEIN | CRYO-EM | TO-HUMAN TRANSMISSION | ACUTE RESPIRATORY SYNDROME | CELL BIOLOGY | ELECTRON CRYOMICROSCOPY | BIOPHYSICS | CD209L L-SIGN | Cell Line | Coronavirus NL63, Human - immunology | Coronavirus NL63, Human - chemistry | Drosophila | Humans | Protein Multimerization | Models, Molecular | Polysaccharides - immunology | Coronavirus Infections - immunology | Polysaccharides - analysis | Cryoelectron Microscopy | Epitopes - immunology | Antibodies, Neutralizing - immunology | Animals | Coronavirus Infections - virology | Protein Conformation | Spike Glycoprotein, Coronavirus - immunology | Epitopes - chemistry | Spike Glycoprotein, Coronavirus - chemistry | Spike Glycoprotein, Coronavirus - ultrastructure | Polysaccharides | Usage | Analysis | Research | Coronaviruses | Electron microscopy | Antigenic determinants | Viruses | Respiratory system | Immune system | Virology | Antibodies, Neutralizing | Coronavirus Infections | Biochemistry, Molecular Biology | Epitopes | Cristallography | Chemical Sciences | Spike Glycoprotein, Coronavirus | Life Sciences | Biomolecules | Coronavirus NL63, Human
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Pre-fusion structure of a human coronavirus spike protein
by Kirchdoerfer, Robert N and Cottrell, Christopher A and Wang, Nianshuang and Pallesen, Jesper and Yassine, Hadi M and Turner, Hannah L and Corbett, Kizzmekia S and Graham, Barney S and McLellan, Jason S and Ward, Andrew B
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 118 - 121
HKU1 is a human betacoronavirus that causes mild yet prevalent respiratory disease1, and is related to the zoonotic SARS(2) and MERS3 betacoronaviruses, which... 
VISUALIZATION | VIRUS | HEMAGGLUTININ | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | VALIDATION | MECHANISMS | GLYCOPROTEIN | CRYO-EM STRUCTURE | ELECTRON-MICROSCOPE | RECEPTOR-BINDING DOMAIN | Protein Structure, Tertiary | Cell Line | Coronavirus - ultrastructure | Spike Glycoprotein, Coronavirus - metabolism | Membrane Fusion | Receptors, Virus - metabolism | Humans | Protein Multimerization | Models, Molecular | Protein Subunits - metabolism | Virus Internalization | Cryoelectron Microscopy | Coronavirus - chemistry | Proteolysis | Protein Structure, Quaternary | Viral Vaccines - chemistry | Protein Binding | Protein Subunits - chemistry | Spike Glycoprotein, Coronavirus - chemistry | Viral Vaccines - immunology | Spike Glycoprotein, Coronavirus - ultrastructure | Physiological aspects | Coronaviruses | Viral proteins | Structure | Proteins | Viruses | Microscopy | Molecular structure | Binding sites
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
by Yuan, Yuan and Cao, Duanfang and Zhang, Yanfang and Ma, Jun and Qi, Jianxun and Wang, Qihui and Lu, Guangwen and Wu, Ying and Yan, Jinghua and Shi, Yi and Zhang, Xinzheng and Gao, George F
Nature Communications, ISSN 2041-1723, 04/2017, Volume 8, Issue 1, p. 15092
The envelope spike (S) proteins of MERS-CoV and SARS-CoV determine the virus host tropism and entry into host cells, and constitute a promising target for the... 
FUSION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | VACCINE | SIALIC-ACID | S-PROTEIN | CORONAVIRUS | NEUTRALIZATION | FEATURES | TOOLS | Antibodies, Neutralizing | Antiviral Agents - pharmacology | Middle East Respiratory Syndrome Coronavirus - ultrastructure | Receptors, Virus - metabolism | Protein Multimerization | Models, Molecular | Glycosylation | Cryoelectron Microscopy | SARS Virus - ultrastructure | Protein Binding | Protein Domains | Glycoproteins - chemistry | Glycoproteins - ultrastructure | Spike Glycoprotein, Coronavirus - chemistry | Membrane Fusion - drug effects | Spike Glycoprotein, Coronavirus - ultrastructure
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
by Walls, Alexandra C and Xiong, Xiaoli and Park, Young-Jun and Tortorici, M. Alejandra and Snijder, Joost and Quispe, Joel and Cameroni, Elisabetta and Gopal, Robin and Dai, Mian and Lanzavecchia, Antonio and Zambon, Maria and Rey, Félix A and Corti, Davide and Veesler, David
Cell, ISSN 0092-8674, 02/2019, Volume 176, Issue 5, pp. 1026 - 1039.e15
Recent outbreaks of severe acute respiratory syndrome and Middle East respiratory syndrome, along with the threat of a future coronavirus-mediated pandemic,... 
glycoproteomics | spike glycoprotein | SARS-CoV | coronavirus | neutralizing antibodies | MERS-CoV | N-linked glycosylation | class I fusion protein | membrane fusion | Biochemistry, Genetics and Molecular Biology(all) | GLYCAN SHIELD | MAXIMUM-LIKELIHOOD | IMMUNOGENICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN MONOCLONAL-ANTIBODY | SPIKE PROTEIN | MERS-COV | BEAM-INDUCED MOTION | BINDING | RESPIRATORY SYNDROME CORONAVIRUS | SARS-CORONAVIRUS | CELL BIOLOGY | SARS Virus - immunology | Chlorocebus aethiops | Spike Glycoprotein, Coronavirus - metabolism | Immunity, Humoral - immunology | Receptors, Virus - metabolism | Humans | Molecular Mimicry - immunology | Coronavirus Infections - immunology | Middle East Respiratory Syndrome Coronavirus - immunology | SARS Virus - metabolism | Virus Internalization | Coronavirus - immunology | Middle East Respiratory Syndrome Coronavirus - metabolism | Spike Glycoprotein, Coronavirus - physiology | Antibodies, Neutralizing - immunology | Animals | Coronavirus - metabolism | HEK293 Cells | Protein Binding | Antibodies, Viral - immunology | Vero Cells | Antibodies, Monoclonal - immunology | Spike Glycoprotein, Coronavirus - ultrastructure | Viral antibodies | Respiratory tract infections | Analysis | Physiological aspects | Antibodies | Glycoproteins | Mass spectrometry | Health aspects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Coronavirus Spike Protein and Tropism Changes
by Hulswit, R J G and de Haan, C A M and Bosch, B-J
Advances in Virus Research, ISSN 0065-3527, 2016, Volume 96, pp. 29 - 57
Coronaviruses (CoVs) have a remarkable potential to change tropism. This is particularly illustrated over the last 15 years by the emergence of two zoonotic... 
Tropism | Receptor interaction | Membrane fusion | Coronavirus spike | Cryo-EM structure | Cross-species transmission | FELINE INFECTIOUS PERITONITIS | MURINE CORONAVIRUS | SARS-LIKE CORONAVIRUS | VIROLOGY | MOUSE HEPATITIS-VIRUS | TRANSMISSIBLE GASTROENTERITIS CORONAVIRUS | RESPIRATORY-SYNDROME-CORONAVIRUS | AMINO-ACID SUBSTITUTIONS | TO-HUMAN TRANSMISSION | PORCINE EPIDEMIC DIARRHEA | RECEPTOR-BINDING DOMAIN | Humans | Virion - genetics | Receptors, Virus - genetics | SARS Virus - metabolism | Virus Internalization | Genetic Variation | SARS Virus - ultrastructure | SARS Virus - genetics | Proteolysis | Protein Domains | Viral Tropism | Protein Subunits - genetics | Gene Expression | Middle East Respiratory Syndrome Coronavirus - ultrastructure | Spike Glycoprotein, Coronavirus - genetics | Models, Molecular | Virion - metabolism | Receptors, Virus - ultrastructure | Middle East Respiratory Syndrome Coronavirus - metabolism | Animals | Receptors, Virus - chemistry | Middle East Respiratory Syndrome Coronavirus - genetics | Virion - ultrastructure | Protein Conformation | Protein Subunits - chemistry | Spike Glycoprotein, Coronavirus - chemistry | Spike Glycoprotein, Coronavirus - ultrastructure
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo‐electron microscopy
by Walls, Alexandra and Tortorici, M. Alejandra and Bosch, Berend‐Jan and Frenz, Brandon and Rottier, Peter J. M and DiMaio, Frank and Rey, Felix A and Veesler, David
Protein Science, ISSN 0961-8368, 01/2017, Volume 26, Issue 1, pp. 113 - 121
The tremendous pandemic potential of coronaviruses was demonstrated twice in the last 15 years by two global outbreaks of deadly pneumonia. Entry of... 
rational vaccine design | cryo‐electron microscopy | coronavirus spike protein | relion | rosetta | cryo-electron microscopy | PARTICLE CRYO-EM | PROTEIN | NEUTRALIZING ANTIBODY | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | EM STRUCTURE DETERMINATION | RECEPTOR | RESPIRATORY SYNDROME CORONAVIRUS | MEMBRANE-FUSION | ELECTRON CRYOMICROSCOPY | Middle East Respiratory Syndrome Coronavirus - ultrastructure | Protein Multimerization | Protein Structure, Quaternary | Models, Molecular | Cryoelectron Microscopy - methods | Middle East Respiratory Syndrome Coronavirus - chemistry | Spike Glycoprotein, Coronavirus - chemistry | Spike Glycoprotein, Coronavirus - ultrastructure | Electron microscopy | Health aspects | Glycoproteins | Microscopy | Cryoelectron Microscopy | Spike Glycoprotein, Coronavirus | Life Sciences | Biochemistry, Molecular Biology | Biomolecules | Cristallography | Chemical Sciences | Middle East Respiratory Syndrome Coronavirus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Cryo-electron microscopy structure of porcine deltacoronavirus spike protein in the prefusion state
by Shang, Jian and Zheng, Yuan and Yang, Yang and Liu, Chang and Geng, Qibin and Tai, Wanbo and Du, Lanying and Zhou, Yusen and Zhang, Wei and Li, Fang
Journal of Virology, ISSN 0022-538X, 02/2018, Volume 92, Issue 4
Coronavirus spike proteins from different genera are divergent, although they all mediate coronavirus entry into cells by binding to host receptors and fusing... 
Membrane fusion | Viral spike glycoprotein | Prefusion | Single-particle reconstruction | Immune evasion | Receptor binding | Cryo-electron microscopy | MOUSE HEPATITIS-VIRUS | CRYSTAL-STRUCTURE | prefusion | SARS-COV | FUSION PEPTIDES | SIALIC-ACID | RESPIRATORY SYNDROME CORONAVIRUS | membrane fusion | viral spike glycoprotein | VIROLOGY | immune evasion | BOVINE CORONAVIRUS | receptor binding | FUNCTIONAL RECEPTOR | CELL ENTRY | RECEPTOR-BINDING | cryo-electron microscopy | single-particle reconstruction | Cryoelectron Microscopy | Coronavirus - ultrastructure | Sf9 Cells | Animals | Swine | Humans | Spike Glycoprotein, Coronavirus - ultrastructure | Spodoptera
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding
by Miao Gui Wenfei Song Haixia Zhou Jingwei Xu Silian Chen Ye Xiang XinquanWang
细胞研究：英文版, ISSN 1001-0602, 2017, Volume 27, Issue 1, pp. 119 - 129
The global outbreak of SARS in 2002-2003 was caused by the infection of a new human coronavirus SARS- CoV. The infection of SARS-CoV is mediated mainly through... 
受体结合位点 | 低温 | 构象状态 | 结构域 | 电子显微镜 | SARS-CoV | 糖蛋白 | SARS冠状病毒 | receptor-binding active state | spike glycoprotein | cryo-EM | RECOMBINATION | S PROTEIN | FUSION | RECOGNITION | BAT CORONAVIRUS | MERS-COV | MECHANISMS | RESPIRATORY SYNDROME CORONAVIRUS | CELL BIOLOGY | REFINEMENT | FUNCTIONAL RECEPTOR | Cryoelectron Microscopy | SARS Virus - ultrastructure | Models, Biological | Humans | Protein Multimerization | Antibodies, Neutralizing - metabolism | Models, Molecular | Protein Binding | Receptors, Cell Surface - metabolism | Protein Conformation | Spike Glycoprotein, Coronavirus - chemistry | Spike Glycoprotein, Coronavirus - ultrastructure | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Structure, Function, and Evolution of Coronavirus Spike Proteins
by Li, Fang
Annual Review of Virology, ISSN 2327-056X, 9/2016, Volume 3, Issue 1, pp. 237 - 261
The coronavirus spike protein is a multifunctional molecular machine that mediates coronavirus entry into host cells. It first binds to a receptor on the host... 
virus origin | coronavirus spike protein | virus evolution | prefusion conformation | receptor binding | postfusion conformation | membrane fusion | Membrane fusion | Prefusion conformation | Postfusion conformation | Virus evolution | Receptor binding | Coronavirus spike protein | Virus origin | MOUSE HEPATITIS-VIRUS | TO-HUMAN TRANSMISSION | RECEPTOR-BINDING DOMAIN | RAY CRYSTAL-STRUCTURE | ANGIOTENSIN-CONVERTING ENZYME-2 | NEUROTROPIC MURINE CORONAVIRUS | VIROLOGY | RESPIRATORY-SYNDROME-CORONAVIRUS | CARCINOEMBRYONIC ANTIGEN FAMILY | SARS-CORONAVIRUS | DIPEPTIDYL PEPTIDASE 4 | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Coronavirus - metabolism | Coronavirus Infections - virology | Membrane Glycoproteins - metabolism | Receptors, Virus - metabolism | Humans | Viral Envelope Proteins - metabolism | Virus Attachment | Membrane Fusion - physiology | Spike Glycoprotein, Coronavirus - ultrastructure | Virus Internalization
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights