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1. Full Text Contribution of the Suppressor of Variegation 3-9 Homolog 1 in Dorsal Root Ganglia and Spinal Cord Dorsal Horn to Nerve Injury–induced Nociceptive Hypersensitivity
by Zhang, Jun and Liang, Lingli and Miao, Xuerong and Wu, Shaogen and Cao, Jing and Tao, Bo and Mao, Qingxiang and Mo, Kai and Xiong, Ming and Lutz, Brianna Marie and Bekker, Alex and Tao, Yuan-Xiang
Anesthesiology (Philadelphia), ISSN 0003-3022, 10/2016, Volume 125, Issue 4, pp. 765 - 778
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Immunohistochemistry | Neuralgia - genetics | Spinal Cord Dorsal Horn - metabolism | Hyperalgesia - metabolism | Methyltransferases - metabolism | Methyltransferases - genetics | Neuralgia - metabolism | Rats | Repressor Proteins - genetics | Male | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | Down-Regulation - genetics | Animals | Hyperalgesia - genetics | Peripheral Nerve Injuries - metabolism | Peripheral Nerve Injuries - genetics | Repressor Proteins - metabolism | Disease Models, Animal | Ganglia, Spinal - metabolism | Index Medicus | Abridged Index Medicus
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2. Full Text Dorsal Horn Circuits for Persistent Mechanical Pain
by Peirs, Cedric and Williams, Sean-Paul G and Zhao, Xinyi and Walsh, Claire E and Gedeon, Jeremy Y and Cagle, Natalie E and Goldring, Adam C and Hioki, Hiroyuki and Liu, Zheng and Marell, Paulina S and Seal, Rebecca P
Neuron (Cambridge, Mass.), ISSN 0896-6273, 08/2015, Volume 87, Issue 4, pp. 797 - 812
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Spinal Cord Dorsal Horn - metabolism | Hyperalgesia - metabolism | Pain - metabolism | Touch | Nerve Net - pathology | Pain - pathology | Hyperalgesia - pathology | Mice, Knockout | Animals | Spinal Cord Dorsal Horn - pathology | Nerve Net - metabolism | Mice | Amino Acid Transport Systems, Acidic - biosynthesis | Organ Culture Techniques | Medical colleges | Neural circuitry | Analysis | Neurophysiology | Spinal cord | Pain | Neurons | Rodents | Morphology | Colleges & universities | Behavior | Control theory | Defects | Index Medicus
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3. Full Text The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn
by Abraira, Victoria E and Kuehn, Emily D and Chirila, Anda M and Springel, Mark W and Toliver, Alexis A and Zimmerman, Amanda L and Orefice, Lauren L and Boyle, Kieran A and Bai, Ling and Song, Bryan J and Bashista, Karleena A and O'Neill, Thomas G and Zhuo, Justin and Tsan, Connie and Hoynoski, Jessica and Rutlin, Michael and Kus, Laura and Niederkofler, Vera and Watanabe, Masahiko and Dymecki, Susan M and Nelson, Sacha B and Heintz, Nathaniel and Hughes, David I and Ginty, David D
Cell (Cambridge), ISSN 0092-8674, 01/2017, Volume 168, Issue 1-2, pp. 295 - 310.e19
somatosensation | synaptic connectivity | low-threshold mechanoreceptors | mouse molecular genetics | spinal cord interneurons | spinal cord dorsal horn | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Touch Perception | Dendrites - metabolism | Spinal Cord - metabolism | Axons - metabolism | Molecular Biology - methods | Neural Pathways | Animals | Interneurons - metabolism | Interneurons - cytology | Mice | Spinal Cord - cytology | Mechanoreceptors - metabolism | Synapses | Animal genetics | Physiological aspects | Medical colleges | Neurons | Neurophysiology | Molecular genetics | Index Medicus
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4. Full Text Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord
by Kardon, Adam P and Polgár, Erika and Hachisuka, Junichi and Snyder, Lindsey M and Cameron, Darren and Savage, Sinead and Cai, Xiaoyun and Karnup, Sergei and Fan, Christopher R and Hemenway, Gregory M and Bernard, Carcha S and Schwartz, Erica S and Nagase, Hiroshi and Schwarzer, Christoph and Watanabe, Masahiko and Furuta, Takahiro and Kaneko, Takeshi and Koerber, H. Richard and Todd, Andrew J and Ross, Sarah E
Neuron (Cambridge, Mass.), ISSN 0896-6273, 05/2014, Volume 82, Issue 3, pp. 573 - 586
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Posterior Horn Cells - metabolism | Spinal Cord - metabolism | Capsaicin - pharmacology | Mice, Inbred C57BL | Receptors, Opioid, kappa - agonists | Analgesics, Opioid - pharmacology | Analgesics, Opioid - therapeutic use | Dynorphins - physiology | Male | Octreotide - pharmacology | Mice, Knockout | Neural Inhibition - physiology | Pruritus - metabolism | Animals | Interneurons - metabolism | Pruritus - prevention & control | Mice | Dynorphins - metabolism | Organ Culture Techniques | Dermatologic agents | Dermatology | Formulae, receipts, prescriptions | Spinal cord | Neurons | Experiments | Rodents | Supervision | Colleges & universities | Index Medicus
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5. Full Text Loss of GABAergic interneurons in laminae I-III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury
by Meisner, Jason G and Marsh, Adam D and Marsh, Daniel R
Journal of neurotrauma, ISSN 0897-7151, 04/2010, Volume 27, Issue 4, pp. 729 - 737
Allodynia | Glutamate decarboxylase | GABA transporter | Thermal hyperalgesia | γ-aminobutyric acid | Neurosciences | Clinical Neurology | Life Sciences & Biomedicine | Critical Care Medicine | Neurosciences & Neurology | General & Internal Medicine | Science & Technology | Pain Threshold - physiology | Posterior Horn Cells - metabolism | Spinal Cord Injuries - complications | Cell Count | Caspase 3 - metabolism | Nerve Degeneration - physiopathology | Neuralgia - metabolism | Apoptosis - genetics | Male | Green Fluorescent Proteins - genetics | Promoter Regions, Genetic - genetics | Nerve Degeneration - metabolism | GABA Plasma Membrane Transport Proteins - metabolism | Neuralgia - etiology | Neuralgia - physiopathology | Nipecotic Acids - pharmacology | GABA Uptake Inhibitors | Disease Models, Animal | Neural Inhibition - genetics | Green Fluorescent Proteins - metabolism | Spinal Cord Injuries - metabolism | Glutamate Decarboxylase - genetics | Mice, Transgenic | Down-Regulation - genetics | Interneurons - pathology | Animals | Interneurons - metabolism | gamma-Aminobutyric Acid - deficiency | GABA Agonists - pharmacology | Posterior Horn Cells - pathology | Glutamate Decarboxylase - metabolism | Mice | Spinal Cord Injuries - physiopathology | Nerve Degeneration - etiology | Pain Measurement | Neural Inhibition - drug effects | Physiological aspects | GABA | Care and treatment | Spinal cord injuries | Neurons | Patient outcomes | Neurotransmitters | Pain | Cellular biology | Index Medicus
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6. Full Text GLT1 overexpression reverses established neuropathic pain‐related behavior and attenuates chronic dorsal horn neuron activation following cervical spinal cord injury
by Falnikar, Aditi and Hala, Tamara J and Poulsen, David J and Lepore, Angelo C
Glia, ISSN 0894-1491, 03/2016, Volume 64, Issue 3, pp. 396 - 406
adeno‐associated virus | neuropathic pain | glutamate transporter | astrocyte | contusion | Contusion | Adeno-associated virus | Astrocyte | Glutamate transporter | Neuropathic pain | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Oncogene Proteins v-fos - metabolism | Pain Threshold - physiology | Posterior Horn Cells - metabolism | Muscle Strength - genetics | Gene Expression Regulation - genetics | Spinal Cord Injuries - complications | Mice, Inbred C57BL | Male | Phosphopyruvate Hydratase - metabolism | Oligodendrocyte Transcription Factor 2 | Functional Laterality | Excitatory Amino Acid Transporter 2 - metabolism | Glial Fibrillary Acidic Protein - metabolism | Motor Neurons - pathology | Spinal Cord Injuries - pathology | Cervical Cord | Nerve Tissue Proteins - metabolism | Tubulin - metabolism | Animals | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neuralgia - etiology | Excitatory Amino Acid Transporter 2 - genetics | Mice | Disease Models, Animal | Care and treatment | Spinal cord injuries | Pain | Glutamate | Neurons | Analysis | Rodents | Index Medicus | adeno-associated virus
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7. Full Text Astrocyte–neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor‐mediated release of glutamate and reactive oxygen species
by Ficker, Christoph and Rozmer, Katalin and Kató, Erzsébet and Andó, Rómeó D and Schumann, Luisa and Krügel, Ute and Franke, Heike and Sperlágh, Beáta and Riedel, Thomas and Illes, Peter
Glia, ISSN 0894-1491, 10/2014, Volume 62, Issue 10, pp. 1671 - 1686
P2X7 receptors | astrocytes | substantia gelatinosa | neurons | ATP | amino acid transmitters | Amino acid transmitters | Astrocytes | Neurons | Substantia gelatinosa | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Microglia - metabolism | Reactive Oxygen Species - metabolism | Spinal Cord Dorsal Horn - metabolism | Rats, Wistar | gamma-Aminobutyric Acid - metabolism | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | CA1 Region, Hippocampal - drug effects | CA1 Region, Hippocampal - metabolism | Neurons - metabolism | Neurons - drug effects | Substantia Gelatinosa - drug effects | Receptors, AMPA - metabolism | Astrocytes - drug effects | Microelectrodes | Tissue Culture Techniques | Substantia Gelatinosa - metabolism | Mice, Transgenic | Hydrogen Peroxide - metabolism | Spinal Cord Dorsal Horn - drug effects | Patch-Clamp Techniques | Animals | Receptors, Purinergic P2X7 - metabolism | Glutamic Acid - metabolism | Astrocytes - metabolism | Methyl aspartate | Muscle proteins | Glutamate | Adenosine triphosphate | Spinal cord | Oxygen | Index Medicus
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8. Full Text Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury
by Petitjean, Hugues and Pawlowski, Sophie Anne and Fraine, Steven Li and Sharif, Behrang and Hamad, Doulia and Fatima, Tarheen and Berg, Jim and Brown, Claire M and Jan, Lily-Yeh and Ribeiro-da-Silva, Alfredo and Braz, Joao M and Basbaum, Allan I and Sharif-Naeini, Reza
Cell reports (Cambridge), ISSN 2211-1247, 11/2015, Volume 13, Issue 6, pp. 1246 - 1257
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Interneurons - physiology | Synapses - physiology | Cells, Cultured | Parvalbumins - metabolism | Neuralgia - pathology | Touch | Spinal Cord Dorsal Horn - physiology | Interneurons - pathology | Spinal Cord Dorsal Horn - physiopathology | Hyperalgesia - pathology | Hyperalgesia - physiopathology | Animals | Interneurons - metabolism | Spinal Cord Dorsal Horn - pathology | Synapses - metabolism | Protein Kinase C - metabolism | Parvalbumins - genetics | Mice | Neuralgia - physiopathology | Index Medicus
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