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1. Full Text A brain-spine interface alleviating gait deficits after spinal cord injury in primates
by Capogrosso, Marco and Capogrosso, Marco and Milekovic, Tomislav and Milekovic, Tomislav and Borton, David and Borton, David and Wagner, Fabien and Wagner, Fabien and Moraud, Eduardo Martin and Moraud, Eduardo Martin and Mignardot, Jean-Baptiste and Mignardot, Jean-Baptiste and Buse, Nicolas and Buse, Nicolas and Gandar, Jerome and Gandar, Jerome and Barraud, Quentin and Barraud, Quentin and Xing, David and Xing, David and Rey, Elodie and Rey, Elodie and Duis, Simone and Duis, Simone and Jianzhong, Yang and Jianzhong, Yang and Ko, Wai Kin D and Ko, Wai Kin D and Li, Qin and Li, Qin and Detemple, Peter and Detemple, Peter and Denison, Tim and Denison, Tim and Micera, Silvestro and Micera, Silvestro and Bezard, Erwan and Bezard, Erwan and Bloch, Jocelyne and Bloch, Jocelyne and Courtine, Grégoire and Courtine, Grégoire
Nature, ISSN 0028-0836, 11/2016, Volume 539, Issue 7628, pp. 284 - 288
Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer... 
MOTOR CONTROL | PARALYSIS | MULTIDISCIPLINARY SCIENCES | NEUROMODULATION | MOVEMENT | LOCOMOTION | FREE BEHAVIOR | MECHANISMS | TRANSLATION | FUNCTIONAL ELECTRICAL-STIMULATION | PROSTHESIS | Studies | Brain research | Transplants & implants | Spinal cord injuries | Muscle function | Paralysis | Monkeys & apes | Index Medicus
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2. Full Text Restoration of grasp following paralysis through brain-controlled stimulation of muscles
by Ethier, C and Oby, E.R and Bauman, M.J and Miller, L.E
Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7398, pp. 368 - 371
Patients with spinal cord injury lack the connections between brain and spinal cord circuits that are essential for voluntary movement. Clinical systems that... 
RECOVERY | IMPLANTED NEUROPROSTHESIS | MULTIDISCIPLINARY SCIENCES | CORD-INJURED POPULATION | MOTOR | MOVEMENT | TETRAPLEGIA | FUNCTIONAL ELECTRICAL-STIMULATION | HAND | PREDICTION | Microelectrodes | Motor Cortex - physiology | Electric Stimulation | Muscles - physiology | Nerve Block | Prostheses and Implants | Electrodes, Implanted | Macaca mulatta | Paralysis - rehabilitation | Quadriplegia - rehabilitation | Hand - physiopathology | Animals | Movement - physiology | Quadriplegia - physiopathology | Paralysis - physiopathology | Spinal Cord Injuries - rehabilitation | Spinal Cord Injuries - physiopathology | Hand - physiology | Hand Strength - physiology | Motor Cortex - cytology | Studies | Electrodes | Spinal cord injuries | Fixed rates | Injuries | Index Medicus
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3. Full Text Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
by Kigerl, Kristina A and Gensel, John C and Ankeny, Daniel P and Alexander, Jessica K and Donnelly, Dustin J and Popovich, Phillip G
Journal of Neuroscience, ISSN 0270-6474, 10/2009, Volume 29, Issue 43, pp. 13435 - 13444
Macrophages dominate sites of CNS injury in which they promote both injury and repair. These divergent effects may be caused by distinct macrophage subsets,... 
FUNCTIONAL RECOVERY | TUMOR-NECROSIS-FACTOR | AUTONOMIC DYSREFLEXIA | COLONY-STIMULATING FACTOR | TRAUMATIC BRAIN-INJURY | TOLL-LIKE RECEPTORS | AXON REGENERATION | NEUROSCIENCES | GROUP BOX-1 PROTEIN | ALTERNATIVE ACTIVATION | MONONUCLEAR PHAGOCYTES | Macrophages - physiology | Cell Survival | Mice, Inbred C57BL | Nerve Regeneration - physiology | Wallerian Degeneration - physiopathology | Cells, Cultured | Chondroitin Sulfate Proteoglycans - metabolism | Axons - physiology | Ganglia, Spinal - physiopathology | Cerebral Cortex - physiopathology | Myelin Sheath - metabolism | Animals | Microglia - physiology | Sensory Receptor Cells - physiology | Time Factors | Mice | Spinal Cord - physiopathology | Spinal Cord Injuries - physiopathology | Monocytes - physiology | Index Medicus | interleukin-4 | spinal cord injury | interferon-γ | neurotoxicity | regeneration | dorsal root ganglion
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4. Full Text Restoring cortical control of functional movement in a human with quadriplegia
by Bouton, Chad E and Shaikhouni, Ammar and Annetta, Nicholas V and Bockbrader, Marcia A and Friedenberg, David A and Nielson, Dylan M and Sharma, Gaurav and Sederberg, Per B and Glenn, Bradley C and Mysiw, W. Jerry and Morgan, Austin G and Deogaonkar, Milind and Rezai, Ali R
Nature, ISSN 0028-0836, 04/2016, Volume 533, Issue 7602, pp. 247 - 250
Millions of people worldwide suffer from diseases that lead to paralysis through disruption of signal pathways between the brain and the muscles.... 
NEUROPROSTHESIS | STIMULATION | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | NEURONS | MOTOR CORTEX | RESTORATION | TETRAPLEGIA | ARM | GRASP | HAND | Microelectrodes | Motor Cortex - physiology | Electric Stimulation | Spinal Cord Injuries - complications | Humans | Male | Electrodes, Implanted | Muscle, Skeletal - physiology | Machine Learning | Cervical Cord - physiopathology | Activities of Daily Living | Quadriplegia - etiology | Young Adult | Magnetic Resonance Imaging | Algorithms | Movement - physiology | Quadriplegia - physiopathology | Imagination | Spinal Cord Injuries - physiopathology | Forearm - physiology | Cervical Cord - physiology | Hand - physiology | Hand Strength - physiology | Cervical Cord - injuries | Human mechanics | Physiological aspects | Quadriplegia | Health aspects | Index Medicus
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5. Full Text Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration
by Ajiboye, A Bolu, Dr and Willett, Francis R, BS and Young, Daniel R, BS and Memberg, William D, MS and Murphy, Brian A, PhD and Miller, Jonathan P, MD and Walter, Benjamin L, MD and Sweet, Jennifer A, MD and Hoyen, Harry A, MD and Keith, Michael W, MD and Peckham, P Hunter, Prof and Simeral, John D, PhD and Donoghue, John P, Prof and Hochberg, Leigh R, Prof and Kirsch, Robert F, Prof
Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10081, pp. 1821 - 1830
Summary Background People with chronic tetraplegia, due to high-cervical spinal cord injury, can regain limb movements through coordinated electrical... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | IMPLANTED NEUROPROSTHESIS | HIGH-LEVEL TETRAPLEGIA | HAND GRASP | DEVICES | SPINAL-CORD-INJURY | PEOPLE | ARM | FUNCTIONAL ELECTRICAL-STIMULATION | CORTICAL CONTROL | Electrodes, Implanted - standards | User-Computer Interface | Self-Help Devices - statistics & numerical data | United States | Brain - physiopathology | Humans | Middle Aged | Male | Motor Cortex - physiopathology | Quadriplegia - surgery | Feasibility Studies | Movement - physiology | Electric Stimulation Therapy - methods | Quadriplegia - physiopathology | Brain-Computer Interfaces - statistics & numerical data | Microelectrodes - adverse effects | Muscle, Skeletal - physiopathology | Quadriplegia - diagnosis | Brain - surgery | United States Department of Veterans Affairs | Spinal Cord Injuries - physiopathology | Spinal Cord Injuries - therapy | Hand - physiology | Hand Strength - physiology | Medical colleges | Neurosciences | Ohio | Quadriplegia | Hospitals | Biomedical engineering | Analysis | Brain | Salts | Fluid flow | pH effects | Eye | Visual system | Restoration | Technology | Surgery | Baclofen | Head and neck | Biocompatibility | Activation analysis | Limbs | Activities of daily living | Motor ability | Medical procedures | Arms | Hand | Appendix | Body mass | Computer applications | Spinal cord injuries | Skin | Added value | Arrays | Viability | Arm | Transplants & implants | Antibodies | Stimulation | Activation | Cortex (somatosensory) | Feedback control | Wrist | Electrodes | Shoulder | pH | Primates | Reliability analysis | Paralysis | Elbow | Hands | Gravitation | Finger | Feasibility studies | Muscles | Imagery | Interfaces | Musculoskeletal system | Algorithms | Control theory | Position (location) | Brain injury | Index Medicus | Abridged Index Medicus
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6. Full Text AOSpine Thoracolumbar Spine Injury Classification System: Fracture Description, Neurological Status, and Key Modifiers
by Vaccaro, Alexander R and Oner, Cumhur and Kepler, Christopher K and Dvorak, Marcel and Schnake, Klaus and Bellabarba, Carlo and Reinhold, Max and Aarabi, Bizhan and Kandziora, Frank and Chapman, Jens and Shanmuganathan, Rajasekaran and Fehlings, Michael and Vialle, Luiz and AOSpine Spinal Cord Injury Trauma and AOSpine Spinal Cord Injury & Trauma Knowledge Forum
Spine, ISSN 0362-2436, 11/2013, Volume 38, Issue 23, pp. 2028 - 2037
STUDY DESIGN.Reliability and agreement study, retrospective case series. OBJECTIVE.To develop a widely accepted, comprehensive yet simple classification system... 
thoracolumbar | accuracy | consensus development | agreement study | spinal injury classification | reliability | POSTERIOR LIGAMENTOUS COMPLEX | MANAGEMENT | PROPOSAL | AGREEMENT | CLINICAL NEUROLOGY | INTEGRITY | ORTHOPEDICS | MORPHOLOGY | Predictive Value of Tests | Spinal Fractures - diagnosis | Reproducibility of Results | Thoracic Vertebrae - diagnostic imaging | Lumbar Vertebrae - injuries | Lumbar Vertebrae - diagnostic imaging | Humans | Terminology as Topic | Consensus | Spinal Fractures - physiopathology | Injury Severity Score | Radiography | Spinal Fractures - classification | Spinal Cord Injuries - classification | Lumbar Vertebrae - pathology | Retrospective Studies | Spinal Cord Injuries - physiopathology | Thoracic Vertebrae - pathology | Observer Variation | Spinal Cord Injuries - diagnosis | Thoracic Vertebrae - injuries | Index Medicus
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7. Full Text Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study
by Harkema, Susan, Prof and Gerasimenko, Yury, PhD and Hodes, Jonathan, MD and Burdick, Joel, Prof and Angeli, Claudia, PhD and Chen, Yangsheng, PhD and Ferreira, Christie, BSc and Willhite, Andrea, BA and Rejc, Enrico, MSc and Grossman, Robert G, Prof and Edgerton, V Reggie, Prof
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9781, pp. 1938 - 1947
Summary Background Repeated periods of stimulation of the spinal cord and training increased the ability to control movement in animal models of spinal cord... 
Internal Medicine | LUMBAR CORD | SPINALIZATION | MEDICINE, GENERAL & INTERNAL | CAT | INJURY | HUMANS | VERTEBRATES | LOCOMOTION | NETWORKS | GENERATE | PLASTICITY | Movement | Spinal Cord Injuries - complications | Humans | Male | Electrodes, Implanted | Paraplegia - etiology | Electric Stimulation Therapy | Leg | Posture | Young Adult | Lumbosacral Region | Paraplegia - therapy | Spinal Cord | Paraplegia - physiopathology | Muscle, Skeletal - physiopathology | Weight-Bearing | Electromyography | Spinal Cord Injuries - physiopathology | Physiological aspects | Paraplegia | Spinal cord | Neural stimulation | Research | Electrodes | Data collection | Legs | Spinal cord injuries | Animal models | Preservation | Proprioception | Recovery of function | Motor vehicles | Spinal cord injury | Electrical stimuli | Plasticity (neural) | Neural networks | Paralysis | Accidents | Index Medicus | Abridged Index Medicus
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8. Full Text Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury
by Wenger, N and Moraud, E.M and Gandar, J and Musienko, P and Capogrosso, M and Baud, L and Le Goff, C.G and Barraud, Q and Pavlova, N and Dominici, N and Minev, I.R and Asboth, L and Hirsch, A and Duis, S and Kreider, J and Mortera, A and Haverbeck, O and Kraus, S and Schmitz, F and DiGiovanna, J and van den Brand, R and Bloch, J and Detemple, P and Lacour, S.P and Bézard, E and Micera, S and Courtine, G
Nature Medicine, ISSN 1078-8956, 2016, Volume 22, Issue 2, pp. 138 - 145
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in animal models and humans. However, the physiological... 
MEDICINE, RESEARCH & EXPERIMENTAL | PRIMITIVES | BIOCHEMISTRY & MOLECULAR BIOLOGY | RATS | POTENTIALS | IDENTIFICATION | LUMBAR | CELL BIOLOGY | CIRCUITS | EPIDURAL ELECTRICAL-STIMULATION | FUNCTIONAL WALKING | LOCOMOTOR NETWORKS | MODULATION | Feedback, Sensory - physiology | Motor Neurons - physiology | Evoked Potentials, Motor - physiology | Rats, Inbred Lew | Rats | Hindlimb - innervation | Muscle, Skeletal - innervation | X-Ray Microtomography | Spinal Cord Injuries - pathology | Hindlimb - physiopathology | Spinal Cord Stimulation | Biomechanical Phenomena | Animals | Spinal Nerve Roots - physiopathology | Time Factors | Computer Simulation | Muscle, Skeletal - physiopathology | Spinal Cord - physiology | Female | Spinal Cord Injuries - rehabilitation | Spinal Cord Injuries - physiopathology | Kinetics | Locomotion - physiology | Physiological aspects | Care and treatment | Neural stimulation | Spinal cord injuries | Cellular biology | Neurons | Motor ability | Medical treatment | Index Medicus | Life Sciences
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9. Full Text A new classification of thoracolumbar injuries: The importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status
by Vaccaro, Alexander R and Lehman Jr, Ronald A and Hurlbert, R. John and Anderson, Paul A and Harris, Mitchel and Hedlund, Rune and Harrop, James and Dvorak, Marcel and Wood, Kirkham and Fehlings, Michael G and Fisher, Charles and Zeiller, Steven C and Anderson, D. Greg and Bono, Christopher M and Stock, Gordon H and Brown, Andrew K and Kuklo, Timothy and Öner, F.C
Spine, ISSN 0362-2436, 10/2005, Volume 30, Issue 20, pp. 2325 - 2333
Study Design. A new proposed classification system for thoracolumbar (TL) spine injuries, including injury severity assessment, designed to assist in clinical... 
Spine trauma | Clinical pathways | Thoracolumbar fractures | Classification | spine trauma | SPINE | thoracolumbar fractures | FRACTURE-DISLOCATIONS | classification | clinical pathways | ORTHOPEDICS | CLINICAL NEUROLOGY | Severity of Illness Index | Lumbar Vertebrae - injuries | Humans | Tomography, X-Ray Computed | Spinal Injuries - physiopathology | Nervous System - physiopathology | Magnetic Resonance Imaging | Spinal Injuries - classification | Longitudinal Ligaments - diagnostic imaging | Spinal Injuries - diagnosis | Longitudinal Ligaments - pathology | Spinal Injuries - diagnostic imaging | Thoracic Vertebrae - injuries | Index Medicus
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10. Full Text Ageing in spinal cord injuries
by Singhal, Raj and Anthony, Angelo and Xiong, Xianghu and Acland, Rick
The New Zealand medical journal, ISSN 0028-8446, 07/2016, Volume 129, Issue 1438, pp. 8 - 11
Witnesses the increase in the post-onset life expectancy of people with a spinal cord injury (SCI) over the past 50 years. Discusses clinical aspects of ageing... 
Spinal cord | Health and hygiene | Wounds and injuries | Patients | Older people | Quality of life | Spasm - physiopathology | Megacolon - physiopathology | Sleep Apnea Syndromes - physiopathology | Humans | Hypotension, Orthostatic - physiopathology | Male | Infertility, Male - physiopathology | Upper Extremity - physiopathology | Urinary Bladder, Neurogenic - physiopathology | Autonomic Dysreflexia - physiopathology | Inappropriate ADH Syndrome - physiopathology | Aging - physiology | Pressure Ulcer - physiopathology | Cumulative Trauma Disorders - physiopathology | Diabetes Mellitus - physiopathology | Scoliosis - physiopathology | Hyponatremia - physiopathology | Metabolic Syndrome - physiopathology | Quality of Life | Spinal Cord Injuries - physiopathology | Neuralgia - physiopathology | Index Medicus
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11. Full Text Targeted neurotechnology restores walking in humans with spinal cord injury
by Wagner, Fabien B and Mignardot, Jean-Baptiste and Le Goff-Mignardot, Camille G and Demesmaeker, Robin and Komi, Salif and Capogrosso, Marco and Rowald, Andreas and Seáñez, Ismael and Caban, Miroslav and Pirondini, Elvira and Vat, Molywan and McCracken, Laura A and Heimgartner, Roman and Fodor, Isabelle and Watrin, Anne and Seguin, Perrine and Paoles, Edoardo and Van Den Keybus, Katrien and Eberle, Grégoire and Schurch, Brigitte and Pralong, Etienne and Becce, Fabio and Prior, John and Buse, Nicholas and Buschman, Rik and Neufeld, Esra and Kuster, Niels and Carda, Stefano and von Zitzewitz, Joachim and Delattre, Vincent and Denison, Tim and Lambert, Hendrik and Minassian, Karen and Bloch, Jocelyne and Courtine, Grégoire
Nature, ISSN 0028-0836, 11/2018, Volume 563, Issue 7729, pp. 65 - 71
Spinal cord injury leads to severe locomotor deficits or even complete leg paralysis. Here we introduce targeted spinal cord stimulation neurotechnologies that... 
EPIDURAL ELECTRICAL-STIMULATION | RECOVERY | EXCITABILITY | MULTIDISCIPLINARY SCIENCES | RANDOMIZED CLINICAL-TRIAL | CIRCUIT REORGANIZATION | MOTOR FUNCTION | NEUROMODULATION | LOCOMOTION | ACTIVITY-BASED THERAPY | PLASTICITY | Humans | Male | Muscle, Skeletal - innervation | Paralysis - rehabilitation | Walking - physiology | Activities of Daily Living | Computer Simulation | Electromyography | Spinal Cord - cytology | Epidural Space | Motor Neurons - physiology | Leg - physiology | Spinal Cord Injuries - surgery | Muscle, Skeletal - physiology | Electric Stimulation Therapy | Leg - innervation | Biomedical Technology | Muscle, Skeletal - physiopathology | Spinal Cord - physiology | Paralysis - physiopathology | Spinal Cord Injuries - rehabilitation | Spinal Cord - physiopathology | Spinal Cord Injuries - physiopathology | Leg - physiopathology | Locomotion - physiology | Paralysis - surgery | Walking | Care and treatment | Spinal cord injuries | Health aspects | Legs | Spinal cord | Nuclear magnetic resonance--NMR | Medical imaging | Activities of daily living | Neurons | Muscles | Pulse generators | Clinical trials | Stimulation | Spinal cord injury | Adaptive control | Electrodes | Ecological effects | Brain research | Simulation | Paralysis | Rehabilitation | Injuries | Index Medicus
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