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science & technology (506) 506
life sciences & biomedicine (459) 459
cell biology (345) 345
animals (319) 319
mitosis (242) 242
humans (238) 238
spindle apparatus - enzymology (208) 208
spindle apparatus - metabolism (202) 202
protein-serine-threonine kinases - metabolism (157) 157
cell cycle (141) 141
cell cycle proteins - metabolism (130) 130
cell division (127) 127
biochemistry & molecular biology (125) 125
research (111) 111
phosphorylation (106) 106
proteins (105) 105
spindle apparatus - drug effects (99) 99
hela cells (97) 97
aurora kinases (92) 92
female (90) 90
mice (89) 89
microtubules (83) 83
protein-serine-threonine kinases - genetics (83) 83
chromosomes (82) 82
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physiological aspects (80) 80
microtubules - metabolism (77) 77
mitosis - physiology (71) 71
molecular sequence data (70) 70
mutation (70) 70
protein kinases - metabolism (69) 69
anaphase (64) 64
cell cycle proteins - genetics (64) 64
spindle (63) 63
spindle apparatus - physiology (63) 63
kinases (62) 62
meiosis (61) 61
fundamental and applied biological sciences. psychology (59) 59
mitotic spindle apparatus (57) 57
protein binding (57) 57
signal transduction (57) 57
centrosome - enzymology (56) 56
oocytes - enzymology (56) 56
saccharomyces cerevisiae - enzymology (55) 55
amino acid sequence (54) 54
genetic aspects (54) 54
spindle apparatus - ultrastructure (54) 54
developmental biology (53) 53
enzyme activation (52) 52
protein transport (52) 52
cytokinesis (51) 51
macromolecular substances (51) 51
mitosis - drug effects (51) 51
metaphase (50) 50
microtubules - enzymology (49) 49
spindle apparatus (49) 49
cell line (48) 48
chromosome segregation (48) 48
microtubule-associated proteins - metabolism (48) 48
yeast (48) 48
cellular biology (47) 47
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saccharomyces cerevisiae - genetics (47) 47
multidisciplinary sciences (46) 46
oncology (46) 46
saccharomyces cerevisiae proteins - metabolism (46) 46
science & technology - other topics (46) 46
kinetochores - metabolism (45) 45
nuclear proteins - metabolism (44) 44
cancer (42) 42
cell line, tumor (41) 41
cells (41) 41
models, biological (41) 41
mitosis - genetics (40) 40
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tubulin - metabolism (40) 40
time factors (39) 39
cell cycle proteins (38) 38
male (38) 38
molecular and cellular biology (38) 38
mutation - genetics (38) 38
proto-oncogene proteins - metabolism (37) 37
research articles (37) 37
schizosaccharomyces - enzymology (37) 37
biology (36) 36
antibodies (35) 35
recombinant fusion proteins - metabolism (34) 34
saccharomyces cerevisiae - cytology (34) 34
cell cycle - physiology (33) 33
cells, cultured (33) 33
phenotype (33) 33
cell physiology (32) 32
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1. Full Text HDAC3 inhibition disrupts the assembly of meiotic apparatus during porcine oocyte maturation
by Gu, Ling and Li, Xiaoyan and Liu, Xiaohui and Gao, Min and He, Yongfu and Xiong, Bo and Liu, Honglin
Journal of cellular physiology, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 10178 - 10183
oocyte | meiosis | HDAC | pig | reproduction | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Meiosis - physiology | Oogenesis - physiology | Histone Deacetylases - metabolism | Meiosis - drug effects | Oocytes - enzymology | Animals | Microtubules - drug effects | Swine | Microtubules - enzymology | Oocytes - drug effects | Female | Histone Deacetylase Inhibitors - pharmacology | Oogenesis - drug effects | Spindle Apparatus - drug effects | Spindle Apparatus - enzymology | Tubulin | Maturation | Microscopy | Deacetylation | Metaphase | Confocal microscopy | Meiosis | Control stability | Inhibition | Assembly | Oocytes | Biological activity | Index Medicus
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2. Full Text Katanin Controls Mitotic and Meiotic Spindle Length
by Karen McNally and Anjon Audhya and Karen Oegema and Francis J. McNally
The Journal of cell biology, ISSN 0021-9525, 12/2006, Volume 175, Issue 6, pp. 881 - 891
Depolymerization | Microtubules | Metaphase | Fluorescence | Embryos | Rotation | Chromosomes | Anaphase | Oocytes | Mitotic spindle apparatus | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Meiosis - physiology | Embryo, Nonmammalian - cytology | Fibroblasts - enzymology | Nocodazole - pharmacology | Caenorhabditis elegans Proteins - metabolism | Caenorhabditis elegans - embryology | Tubulin - metabolism | Animals | Caenorhabditis elegans - cytology | Embryo, Nonmammalian - enzymology | Microtubules - drug effects | Fibroblasts - drug effects | Microtubules - enzymology | Female | Katanin | Fibroblasts - cytology | Spindle Apparatus - ultrastructure | Adenosine Triphosphatases - physiology | Caenorhabditis elegans - enzymology | Spindle Apparatus - enzymology | Cell division | Physiological aspects | Eukaryotes | Cellular biology | Cells | Index Medicus
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3. Full Text The Small Molecule Hesperadin Reveals a Role for Aurora B in Correcting Kinetochore-Microtubule Attachment and in Maintaining the Spindle Assembly Checkpoint
by Silke Hauf and Richard W. Cole and Sabrina LaTerra and Christine Zimmer and Gisela Schnapp and Rainer Walter and Armin Heckel and Jacques van Meel and Conly L. Rieder and Jan-Michael Peters
The Journal of cell biology, ISSN 0021-9525, 4/2003, Volume 161, Issue 2, pp. 281 - 294
Mitosis | Kinetochores | Chromatids | Microtubules | HeLa cells | Cellular immunity | Chromosomes | Anaphase | Cells | Mitotic spindle apparatus | Chemical biology | Spindle assembly checkpoint | Chromosome segregation | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Cycle Proteins - drug effects | Protein Kinases - metabolism | RNA, Small Interfering - genetics | Paclitaxel - pharmacology | Humans | Nocodazole - pharmacology | Chromosome Segregation - drug effects | Mitosis - genetics | Aurora Kinase B | Microtubules - drug effects | Spindle Apparatus - genetics | Cell Cycle Proteins - genetics | Genes, cdc - physiology | Indoles - pharmacology | Kinetochores - enzymology | Protein-Serine-Threonine Kinases - metabolism | Aneugens - pharmacology | Eukaryotic Cells - enzymology | Polyploidy | Protein Kinases - drug effects | Separase | Protein-Serine-Threonine Kinases - genetics | Genes, cdc - drug effects | Aurora Kinases | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Anaphase - drug effects | Phenotype | Anaphase - genetics | Animals | Eukaryotic Cells - drug effects | Mitosis - drug effects | Microtubules - genetics | Microtubules - enzymology | Protein-Serine-Threonine Kinases - drug effects | Eukaryotic Cells - cytology | Kinetochores - drug effects | Spindle Apparatus - drug effects | HeLa Cells | Thiones - pharmacology | Endopeptidases | Chromosome Segregation - genetics | Spindle Apparatus - enzymology | Research | Molecules | Genes | Index Medicus | mitosis; chromosome segregation; kinetochores; spindle assembly checkpoint; chemical biology
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4. Full Text PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells
by Jiang, Yuhui and Li, Xinjian and Yang, Weiwei and Hawke, David H and Zheng, Yanhua and Xia, Yan and Aldape, Kenneth and Wei, Chongyang and Guo, Fang and Chen, Yan and Lu, Zhimin
Molecular cell, ISSN 1097-2765, 01/2014, Volume 53, Issue 1, pp. 75 - 87
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Glioblastoma - enzymology | Mitosis | Humans | Neoplasm Proteins - metabolism | Poly-ADP-Ribose Binding Proteins | Glioblastoma - genetics | Spindle Apparatus - genetics | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Kinetochores - enzymology | Brain Neoplasms - enzymology | Chromosome Segregation | Membrane Proteins - genetics | Chromosomes, Human - genetics | Cell Cycle Proteins - metabolism | Brain Neoplasms - genetics | Chromosomes, Human - metabolism | Thyroid Hormones - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Mice, Nude | Thyroid Hormones - metabolism | Mice | HeLa Cells | Spindle Apparatus - enzymology | Genetic research | Glucose metabolism | Epidermal growth factor | Genetic transcription | Gliomas | Protein binding | Brain tumors | Chromosomes | Protein kinases | Index Medicus | spindle-assembly checkpoint | PKM2 | kinetochore | Bub3 | tumorigenesis | phosphorylation | EGFR
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5. Full Text Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells
by Ertych, Norman and Stolz, Ailine and Stenzinger, Albrecht and Weichert, Wilko and Kaulfuß, Silke and Burfeind, Peter and Aigner, Achim and Wordeman, Linda and Bastians, Holger
Nature cell biology, ISSN 1465-7392, 2014, Volume 16, Issue 8, pp. 779 - 791
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Caco-2 Cells | Colorectal Neoplasms - enzymology | Gene Expression | Colorectal Neoplasms - genetics | HCT116 Cells | Humans | Spindle Apparatus - pathology | Microtubules - pathology | HT29 Cells | BRCA1 Protein - genetics | Checkpoint Kinase 2 - genetics | Microtubules - genetics | Models, Biological | Microtubules - enzymology | Spindle Apparatus - genetics | Cell Line, Tumor | Colorectal Neoplasms - pathology | Chromosomal Instability | Genes, Tumor Suppressor | Aurora Kinase A - genetics | Oncogenes | Chromosome Segregation - genetics | Spindle Apparatus - enzymology | Development and progression | Genetic aspects | Properties | Chromosomes | Microtubules | Colorectal cancer | Index Medicus
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6. Full Text Moesin and Its Activating Kinase Slik Are Required for Cortical Stability and Microtubule Organization in Mitotic Cells
by Sébastien Carreno and Ilektra Kouranti and Edith Szafer Glusman and Margaret T. Fuller and Arnaud Echard and François Payre
The Journal of cell biology, ISSN 0021-9525, 2/2008, Volume 180, Issue 4, pp. 739 - 746
Phosphorylation | Double stranded RNA | Mitosis | Report | Metaphase | Microtubules | Drosophila | Cell division | Actins | Cytokinesis | Mitotic spindle apparatus | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Prometaphase - physiology | Cytoskeleton - enzymology | Cytokinesis - physiology | Microtubules - ultrastructure | Membrane Proteins - metabolism | Spindle Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Cytoskeleton - pathology | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Cell Membrane - ultrastructure | Cytoskeleton - ultrastructure | Drosophila melanogaster - ultrastructure | Microtubules - pathology | Mutation - genetics | Actomyosin - metabolism | Down-Regulation - genetics | Cell Membrane - enzymology | Animals | Membrane Proteins - antagonists & inhibitors | Mitosis - physiology | Microtubules - enzymology | Drosophila melanogaster - enzymology | Drosophila Proteins - genetics | Enzyme Activation - genetics | Spindle Apparatus - enzymology | Evaluation | Cell research | Physiological aspects | Properties | Biochemistry | Insects | Kinases | Chromosomes | Index Medicus | s
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7. Full Text The multifaceted allosteric regulation of Aurora kinase A
by Levinson, Nicholas Mark
Biochemical journal, ISSN 0264-6021, 06/2018, Volume 475, Issue 12, pp. 2025 - 2042
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Neuroblastoma - enzymology | Melanoma - enzymology | Male | Neoplasm Proteins - antagonists & inhibitors | Aurora Kinase A - antagonists & inhibitors | Neoplasm Proteins - metabolism | Aurora Kinase A - metabolism | Phosphorylation - genetics | Prostatic Neoplasms - genetics | Melanoma - genetics | Spindle Apparatus - genetics | Protein Domains | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Aurora Kinase A - genetics | Prostatic Neoplasms - drug therapy | Allosteric Regulation - drug effects | Allosteric Regulation - genetics | Centromere - enzymology | Neuroblastoma - genetics | Enzyme Activation - drug effects | Animals | Centromere - genetics | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Neuroblastoma - drug therapy | Prostatic Neoplasms - enzymology | Enzyme Activation - genetics | Spindle Apparatus - enzymology | Index Medicus | Review | allosteric regulation | aurora kinases | protein dynamics
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8. Full Text MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway
by Gruber, Ralph and Zhou, Zhongwei and Sukchev, Mikhail and Joerss, Tjard and Frappart, Pierre-Olivier and Wang, Zhao-Qi
Nature cell biology, ISSN 1465-7392, 11/2011, Volume 13, Issue 11, pp. 1325 - 1334
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neocortex - pathology | Protein Kinases - metabolism | Protein Kinases - genetics | Cell Proliferation | Microcephaly - genetics | Mitosis | Neocortex - enzymology | Microcephaly - enzymology | Transfection | RNA Interference | Microcephaly - pathology | Cell Differentiation | cdc25 Phosphatases - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Signal Transduction | Cells, Cultured | Organ Size | cdc25 Phosphatases - genetics | Neural Stem Cells - enzymology | Neural Stem Cells - pathology | Chromosomal Proteins, Non-Histone - deficiency | Chromosomal Proteins, Non-Histone - genetics | Mice, Knockout | Animals | Centrosome - enzymology | Checkpoint Kinase 1 | Mice | Spindle Apparatus - enzymology | DNA damage | Centrosomes | Physiological aspects | Genetic aspects | Research | Microcephaly | Risk factors | Index Medicus
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9. Full Text Antibodies to mitotic apparatus: New association with cholestatic liver disease
by Pascual, Virginia and Perez, Irene and Sánchez-Ramón, Silvia and Sánchez-Pobre, Pilar
The American journal of gastroenterology, ISSN 0002-9270, 12/2015, Volume 110, Issue 12, pp. 1736 - 1737
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Autoimmunity | Cholestasis - immunology | Liver Diseases - immunology | Liver Diseases - genetics | Cholestasis - enzymology | Autoantibodies - blood | Humans | Liver Diseases - enzymology | Medical Records | Transaminases - blood | Retrospective Studies | Spindle Apparatus - immunology | Index Medicus
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10. Full Text The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis
by Vazquez-Martin, Alejandro and Oliveras-Ferraros, Cristina and Menendez, Javier A
Cell cycle (Georgetown, Tex.), ISSN 1538-4101, 08/2009, Volume 8, Issue 15, pp. 2385 - 2398
Genome instability | AMPK | Cytokinesis | Mitosis | Tumor suppressor | Life Sciences & Biomedicine | Science & Technology | Cell Biology | AMP-Activated Protein Kinases - metabolism | Chromosome Segregation | Humans | Anaphase - physiology | Aurora Kinases | Aurora Kinase A | Aurora Kinase B | Tubulin - metabolism | Animals | Centrosome - enzymology | Cell Line, Tumor | Mice | Telophase - physiology | Spindle Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | Spindle Apparatus - enzymology | Index Medicus
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