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Journal Article
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 03/2008, Volume 73, Issue 3, pp. 789 - 800
In addition to being an important receptor in leukocyte activation and mobilization, CCR5 is the essential coreceptor for human immunodeficiency virus (HIV). A... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Anti-HIV Agents - pharmacology | Benzoates - metabolism | Humans | Receptors, CCR5 - genetics | Piperazines - chemistry | Pyrimidines - metabolism | Receptors, CCR5 - metabolism | Piperidines - pharmacology | Amides - metabolism | Anti-HIV Agents - metabolism | Radioligand Assay | Binding Sites | Amides - pharmacology | Anti-HIV Agents - classification | Amino Acid Sequence | Piperidines - metabolism | Models, Molecular | Pyrimidines - pharmacology | HIV Fusion Inhibitors - pharmacology | Piperazines - pharmacology | Triazoles - metabolism | Anti-HIV Agents - chemistry | Amides - chemistry | Benzoates - pharmacology | Hydrophobic and Hydrophilic Interactions | Receptors, CCR5 - chemistry | Quaternary Ammonium Compounds - pharmacology | Cricetulus | Triazoles - chemistry | Benzoates - chemistry | Cyclohexanes - pharmacology | Molecular Sequence Data | Piperazines - metabolism | Quaternary Ammonium Compounds - chemistry | Pyrimidines - chemistry | Cyclohexanes - metabolism | Transfection | Inhibitory Concentration 50 | Cyclohexanes - chemistry | Molecular Structure | Membrane Fusion - drug effects | Spiro Compounds - chemistry | CCR5 Receptor Antagonists | CHO Cells | Protein Structure, Tertiary | Cricetinae | Piperidines - chemistry | Mutagenesis, Site-Directed | Protein Structure, Secondary | HIV-1 - drug effects | Static Electricity | Sequence Homology, Amino Acid | Triazoles - pharmacology | Animals | Quaternary Ammonium Compounds - metabolism | Spiro Compounds - pharmacology | Spiro Compounds - metabolism | Index Medicus
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 08/2014, Volume 24, Issue 16, pp. 3673 - 3682
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 3/2010, Volume 107, Issue 13, pp. 6076 - 6081
Spirolide and gymnodimine macrocyclic imine phycotoxins belong to an emerging class of chemical agents associated with marine algal blooms and shelfish... 
Receptors | Imines | Shellfish | Ligands | Agonists | Toxins | Pharmacology | Nicotinic receptors | Nitrogen | Oocytes | Pharmacological and structural analyses | Seafood poisoning | Acetylcholine binding protein | Nicotinic acetylcholine receptor | Marine phycotoxins | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Heterocyclic Compounds, 3-Ring - metabolism | Heterocyclic Compounds, 3-Ring - pharmacology | Nicotinic Antagonists - metabolism | Humans | Aplysia - metabolism | Crystallography, X-Ray | Acetylcholine - metabolism | Nicotinic Antagonists - pharmacology | Hydrocarbons, Cyclic - pharmacology | Imines - chemistry | Oocytes - drug effects | Carrier Proteins - chemistry | Female | Molecular Structure | Spiro Compounds - chemistry | Receptors, Nicotinic - metabolism | Marine Toxins - metabolism | Oocytes - metabolism | Imines - metabolism | Models, Molecular | Electric Organ - metabolism | Marine Toxins - pharmacology | Imines - pharmacology | Macromolecular Substances | Animals | Carrier Proteins - metabolism | Xenopus - metabolism | Marine Toxins - chemistry | Nicotinic Antagonists - chemistry | Heterocyclic Compounds, 3-Ring - chemistry | Torpedo - metabolism | Kinetics | In Vitro Techniques | Hydrocarbons, Cyclic - chemistry | Spiro Compounds - pharmacology | Hydrocarbons, Cyclic - metabolism | Spiro Compounds - metabolism | Marine toxins | Crystals | Physiological aspects | Acetylcholine | Structure | Properties | Protein binding | Proteins | Neurons | Chemical compounds | Binding sites | Crystal structure | Index Medicus | Life Sciences | Neurons and Cognition | Biological Sciences | acetylcholine binding protein | seafood poisoning | marine phycotoxins | pharmacological and structural analyses | nicotinic acetylcholine receptor
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 03/2009, Volume 324, Issue 5928, pp. 801 - 804
... lysis and bacterial death. The most advanced compound, BTZ043, is a candidate for inclusion in combination therapies for both drug-sensitive and extensively drug-resistant TB. 
Enzymes | Antibacterials | Tuberculosis | Mycobacterium tuberculosis | Cell walls | Antituberculars | Bacteria | Reports | Biochemistry | Enantiomers | Codons | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antitubercular Agents - chemical synthesis | Antitubercular Agents - chemistry | Thiazines - therapeutic use | Ethambutol - pharmacology | Drug Resistance, Bacterial | Molecular Sequence Data | Spiro Compounds - therapeutic use | Tuberculosis - microbiology | Mycobacterium tuberculosis - drug effects | Polysaccharides - biosynthesis | Microbial Sensitivity Tests | Racemases and Epimerases - metabolism | Enzyme Inhibitors - chemistry | Spiro Compounds - chemical synthesis | Tuberculosis - drug therapy | Arabinose - metabolism | Thiazines - pharmacology | Molecular Structure | Mycobacterium tuberculosis - metabolism | Spiro Compounds - chemistry | Antitubercular Agents - therapeutic use | Amino Acid Sequence | Genes, Bacterial | Antitubercular Agents - pharmacology | Enzyme Inhibitors - pharmacology | Racemases and Epimerases - antagonists & inhibitors | Enzyme Inhibitors - therapeutic use | Thiazines - chemical synthesis | Thiazines - chemistry | Mycobacterium - genetics | Mycobacterium - drug effects | Gene Expression Regulation, Bacterial - drug effects | Animals | Cell Wall - metabolism | Enzyme Inhibitors - cerebrospinal fluid | Mice | Mice, Inbred BALB C | Spiro Compounds - pharmacology | Mycobacterium tuberculosis - genetics | Antitubercular agents | Dosage and administration | Drug therapy | Genetics | Pharmacology | Chemical synthesis | Index Medicus
Journal Article
PLoS neglected tropical diseases, ISSN 1935-2735, 08/2019, Volume 13, Issue 8, pp. e0007573 - e0007573
... with: Shunyu Li, Jin-Ho Song Roles Formal analysis, Writing – review & editing Affiliation: Department of Pharmacology, Chung-Ang University College of Medicine, Seoul... 
Infectious Diseases | Parasitology | Life Sciences & Biomedicine | Science & Technology | Tropical Medicine | Peptide YY - pharmacology | Sulpiride - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Dopamine - pharmacology | Fluorenes - pharmacology | Neuropeptide Y - pharmacology | Chemotaxis - drug effects | Clonorchis sinensis - drug effects | Piperazines - pharmacology | Fasciola hepatica - drug effects | Animals | Chemotaxis - physiology | Serotonin Agents - pharmacology | Biphenyl Compounds - pharmacology | Neurotransmitter Agents - pharmacology | Excitatory Amino Acid Agents - pharmacology | Clonorchis sinensis - physiology | Benzamides - pharmacology | Cholic Acid | FMRFamide - pharmacology | Spiro Compounds - pharmacology | Neurosciences | Motility | Peptides | Leukocyte migration | Nervous system | Neuropeptides | Biology | Parasites | Cholic acid | Juveniles | Sulpiride | Neuromodulation | Modulators | FMRFamide | Proteins | Receptors | Dopamine D2 receptors | Minors | University colleges | Neuropeptide Y | Dopamine | Serotonin | Duodenum | Neurons | Fluoxetine | Immunomodulation | Cloning | Dopamine D3 receptors | Muscles | Chemotaxis | Bile duct | Cholinergics | Medicine | Inhibitors | Dopamine D1 receptors | Acids | Glutamatergic transmission | Laboratory animals | Immunofluorescence | Cell migration | Bile | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 08/2004, Volume 430, Issue 7002, pp. 900 - 904
Journal Article
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 12/2018, Volume 63, Issue 1
Artesunate (AS), a semisynthetic artemisinin approved for malaria therapy, inhibits human cytomegalovirus (HCMV) replication , but therapeutic success in... 
Half-life | Artemisinins | Pharmacokinetics | Mouse cytomegalovirus | Ozonides | Human cytomegalovirus | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Antiviral Agents - pharmacokinetics | Humans | Male | Host-Pathogen Interactions - drug effects | CDC2 Protein Kinase - metabolism | Microbial Sensitivity Tests | Heterocyclic Compounds, 1-Ring - chemistry | Antiviral Agents - chemistry | Heterocyclic Compounds, 1-Ring - pharmacology | Isoenzymes - metabolism | Cytomegalovirus Infections - virology | Female | Ganciclovir - pharmacology | Drug Evaluation, Preclinical | Spiro Compounds - chemistry | Fibroblasts - virology | Cell Line | Cytomegalovirus - genetics | Virus Replication - drug effects | Antiviral Agents - pharmacology | CDC2 Protein Kinase - genetics | Drug Administration Schedule | Signal Transduction | Antiviral Agents - blood | Heterocyclic Compounds, 1-Ring - pharmacokinetics | Isoenzymes - genetics | Cytomegalovirus - metabolism | Retinoblastoma Protein - metabolism | Gene Expression Regulation | E2F1 Transcription Factor - metabolism | Fibroblasts - pathology | Spiro Compounds - pharmacokinetics | Drug Resistance, Viral - genetics | Animals | Cytomegalovirus Infections - drug therapy | Retinoblastoma Protein - genetics | Fibroblasts - drug effects | Spiro Compounds - blood | Drug Resistance, Viral - drug effects | Mice | Mice, Inbred BALB C | Heterocyclic Compounds, 1-Ring - blood | E2F1 Transcription Factor - genetics | Spiro Compounds - pharmacology | Cytomegalovirus - drug effects | Index Medicus
Journal Article