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chemistry, organic (60) 60
spiropyrrolidines (44) 44
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1,3-dipolar cycloaddition (32) 32
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azomethine ylide (26) 26
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Tetrahedron, ISSN 0040-4020, 02/2017, Volume 73, Issue 7, pp. 923 - 930
Here, we report a convenient access to diastereoselective synthesis of polysubstituted pyrrolidines bearing a unique spiro quaternary center at the C-2... 
1, 3-Dipolar cycloaddition | Quaternary center | Spiropyrrolidine | Spirolactone
Journal Article
Tetrahedron, ISSN 0040-4020, 2010, Volume 66, Issue 34, pp. 6744 - 6748
A facile one-pot synthesis of chromene bearing novel spiropyrrolidine-oxindoles has been accomplished by the [3+‏2]-cycloaddition reaction of 3-acetyl-2... 
Chromeno[3,4- c]spiropyrrolidine-oxindole | 1,3-Dipolar cycloaddition | Azomethine ylide | Chromeno[3,4-c]spiropyrrolidine- oxindole | Chromeno[3,4-c]spiropyrrolidine-oxindole | RECEPTOR ANTAGONISTS | CONSTRUCTION | AZOMETHINE YLIDES | CHEMISTRY, ORGANIC | DERIVATIVES | INTRAMOLECULAR CYCLOADDITION | Schiff bases
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 11/2019, p. 126789
Journal Article
Synthetic Communications, ISSN 0039-7911, 10/2016, Volume 46, Issue 20, pp. 1643 - 1664
Spirocyclic compounds isolated from plant and animal origins have important applications in medicinal chemistry. Spiro compounds having cyclic structures fused... 
spirocyclic | oxindole | spiropyrrolidines | Azomethine ylide | 1,3-dipolar cycloaddition | 1, 3-dipolar cycloaddition | 1,3-DIPOLAR CYCLOADDITIONS | AZOMETHINE YLIDES | CHEMISTRY, ORGANIC | SARCOSINE | DISCOVERY | ACETYLCHOLINESTERASE | INHIBITORS | FACILE | DERIVATIVES
Journal Article
Asian Journal of Chemistry, ISSN 0970-7077, 04/2016, Volume 28, Issue 4, pp. 765 - 770
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 08/2018, Volume 59, Issue 35, pp. 3336 - 3340
Stereoselective syntheses of novel dispiro acenaphthylene-indolizine-pyridinone hybrid heterocycles have been achieved for the first time through one-pot... 
X-ray studies | 1,3-Dipolar cycloaddition | Dihydropyridinones | Spiro heterocyclic hybrids | Domino reaction | CHOLINESTERASE INHIBITORY-ACTIVITY | CHEMISTRY, ORGANIC | MOLECULAR DOCKING | SPIROPYRROLIDINES | DISCOVERY | EXPEDIENT | STEREOSELECTIVE-SYNTHESIS | AMARYLLIDACEAE | DERIVATIVES | ALKALOIDS
Journal Article
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 04/2019, Volume 84, Issue 7, pp. 4273 - 4281
A regio- and diastereoselective 1,3-dipolar cycloaddition of 2H-azirines with azomethine ylides generated in situ from isatins and alpha-amino acids has been... 
PYRROLIDINE | POTENT | AQUEOUS-MEDIUM | CHEMISTRY, ORGANIC | DIVERSITY | ENANTIOSELECTIVE CONSTRUCTION | DERIVATIVES | CYCLIZATION | DISCOVERY | FUSED SPIROPYRROLIDINE OXINDOLES | IMIDAZOLIDINES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 03/2015, Volume 56, Issue 12, pp. 1539 - 1544
A facile one-pot synthesis of carbohydrate derived spiro heterocycles via [3+2] cycloaddition reaction of azomethine ylides is described. A unique... 
1,3-Dipolar cycloaddition | Carbohydrates | Spirooxindoles | Spiropyrrolidines | Azomethine ylide | ROUTE | ENANTIOSELECTIVE SYNTHESIS | MIMICS | EXPEDIENT SYNTHESIS | AZOMETHINE YLIDES | CHEMISTRY, ORGANIC | NITRONE | CONSTRUCTION | (+/-)-HORSFILINE | REGIOSELECTIVE SYNTHESIS | STRUCTURE-BASED DESIGN
Journal Article
RSC Advances, 12/2013, Volume 4, Issue 5, pp. 2263 - 2266
Structurally complex spiro analogues of indenoquinoxaline have been synthesized via the cycloaddition reaction of azomethine ylides with alkyl... 
Acetates
Journal Article
RSC Advances, ISSN 2046-2069, 2014, Volume 4, Issue 5, pp. 2263 - 2266
Structurally complex spiro analogues of indenoquinoxaline have been synthesized via the cycloaddition reaction of azomethine ylides with alkyl... 
1,3-DIPOLAR CYCLOADDITION REACTION | ECHINOMYCIN | MULTICOMPONENT | FACILE SYNTHESIS | CONSTRUCTION | SEQUENCE | STEREOSELECTIVE-SYNTHESIS | INHIBITORS | PYRROLIZIDINES | CHEMISTRY, MULTIDISCIPLINARY | SPIROPYRROLIDINES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 08/2015, Volume 56, Issue 35, pp. 4980 - 4983
A convenient one-pot synthesis of 2-benzoxepines generated from ( )-2-nitro-3-arylprop-2-en-1-ols with paraformaldehyde via oxa-Pictet–Spengler cyclization is... 
Benzoxepinopyrrolidines/spiropyrrolidines | 1,3-Dipolar cycloaddition | Regioselectivity | Nitrobenzoxepines | TRANSFORMATION | ASPERGILLUS-FUMIGATUS | CHEMISTRY, ORGANIC | OXINDOLE | CARBONYL YLIDES | BAYLIS-HILLMAN ADDUCTS | TANDEM CONSTRUCTION | FACILE SYNTHESIS | HETEROCYCLES | CELL CYCLE INHIBITORS | DERIVATIVES | Oxalic acid | Schiff bases
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2010, Volume 51, Issue 7, pp. 1064 - 1068
A series of dispiropyrrolidine bisoxindoles were synthesized via a multicomponent 1,3-dipolar cycloaddition reaction of isatin, sarcosine and isatylidene... 
Isatylidene malononitrile | Dipolarophile | Spiropyrrolidine oxindoles | 3-Diones | Spiroindane-1 | Multi-component reaction | ISATIN | ONE-POT | AZOMETHINE YLIDES | CHEMISTRY, ORGANIC | DIPOLAROPHILES | SYSTEMS | FACILE | DERIVATIVES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2007, Volume 48, Issue 40, pp. 7164 - 7168
One-pot, three-component tandem reactions of cyclic mono ketones, isatin and sarcosine affording dispiropyrrolidines stereoselectively are reported for the... 
Spiropyrrolidines | Ketones | Tandem reactions | Isatin | Sarcosine | Azomethine ylide | ORGANIC-SYNTHESIS | azomethine ylide | DOMINO REACTIONS | sarcosine | CHEMISTRY, ORGANIC | ketones | isatin | spiropyrrolidines | CYCLOADDITION | PYRROLIDINES | HETEROCYCLES | INHIBITORS | tandem reactions | Schiff bases
Journal Article
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