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The Journal of clinical investigation, ISSN 0021-9738, 2006, Volume 116, Issue 4, pp. 916 - 928
Journal Article
American Journal of Physiology: Cell Physiology, ISSN 1522-1563, 2007, Volume 293, Issue 2, pp. C641 - C649
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 9/2009, Volume 106, Issue 38, pp. 16381 - 16386
We used the muscle creatine kinase (MCK) conditional frataxin knockout mouse to elucidate how frataxin deficiency alters iron metabolism... 
Up regulation | Molecules | Mitochondria | Energy metabolism | Messenger RNA | Reverse transcriptase polymerase chain reaction | Lead | Iron | Friedreich ataxia | Down regulation | Frataxin | Iron transferrin | Heme synthesis | heme synthesis | FRATAXIN EXPRESSION | HEME-SYNTHESIS | MULTIDISCIPLINARY SCIENCES | transferrin | HOMOLOG | INTERLEUKIN-6 | MATURATION | DEFICIENCY | frataxin | CLUSTER SYNTHESIS | METABOLISM | iron | MICE | PROTEINS | Heme - metabolism | Oligonucleotide Array Sequence Analysis | Friedreich Ataxia - pathology | Humans | Gene Expression Profiling | Antimicrobial Cationic Peptides - metabolism | Iron-Binding Proteins - metabolism | Friedreich Ataxia - genetics | Kidney - metabolism | Carbon-Sulfur Lyases - genetics | Hepcidins | Myocardium - metabolism | Antimicrobial Cationic Peptides - genetics | Disease Models, Animal | Friedreich Ataxia - metabolism | Liver - metabolism | Uroporphyrinogen III Synthetase - genetics | Uroporphyrinogen III Synthetase - metabolism | Mitochondria - metabolism | Coproporphyrinogen Oxidase - genetics | Reverse Transcriptase Polymerase Chain Reaction | Carbon-Sulfur Lyases - metabolism | Iron - metabolism | Blotting, Western | Mice, Knockout | Myocardium - cytology | Animals | Spleen - metabolism | Ferrochelatase - metabolism | Ferrochelatase - genetics | Iron-Binding Proteins - genetics | Mice | Coproporphyrinogen Oxidase - metabolism | Biological Sciences
Journal Article
The Journal of infectious diseases, ISSN 1537-6613, 2011, Volume 204, Issue 5, pp. 731 - 740
Microbial pathogens have evolved mechanisms to overcome immune responses and successfully infect their host. Here, we studied how Listeria monocytogenes evades... 
Spleen | Listeria | Cytokines | Cell walls | Liver | Virulence | Listeria monocytogenes | Bacteria | Infections | Macrophages | INFECTIOUS DISEASES | IFN-GAMMA | NEUTROPHILS | MICROBIOLOGY | IMMUNOLOGY | RESPONSES | TUMOR-NECROSIS-FACTOR | INTERFERON | DEFICIENT | RESISTANCE | INTERLEUKIN-6-DEFICIENT MICE | STAPHYLOCOCCUS-AUREUS | INFECTION | Virulence Factors - genetics | Humans | Peptidoglycan - chemistry | Liver - microbiology | Virulence Factors - immunology | Listeria monocytogenes - immunology | Peptidoglycan - immunology | Acetyltransferases - genetics | Spleen - microbiology | Microbial Sensitivity Tests | Th1 Cells - metabolism | Listeriosis - immunology | Female | Acetylation | Macrophages - immunology | Cell Line | Cytokines - metabolism | Listeriosis - genetics | Liver - metabolism | Listeria monocytogenes - growth & development | Lethal Dose 50 | Immunity, Innate | Th2 Cells - metabolism | Listeria monocytogenes - pathogenicity | Macrophages - metabolism | Animals | Listeria monocytogenes - genetics | Mice | Mice, Inbred BALB C | Acetyltransferases - immunology | Muramic Acids - metabolism | Causes of | Genetic aspects | Bacterial infections | Research | Peptidoglycans | Macrophages/metabolism | Th1 Cells/metabolism | Macrophages/immunology | Listeria monocytogenes/genetics | Virulence Factors/genetics | Listeriosis/immunology | Life Sciences | Immunology | Liver/metabolism | Acetyltransferases/immunology | Listeria monocytogenes/pathogenicity | Listeria monocytogenes/growth & development | Listeria monocytogenes/immunology | Cytokines/metabolism | Spleen/microbiology | Liver/microbiology | Muramic Acids/metabolism | Peptidoglycan/chemistry | Th2 Cells/metabolism | Listeriosis/genetics | Peptidoglycan/immunology | Virulence Factors/immunology | Acetyltransferases/genetics | Major and Brief Reports
Journal Article
Nature medicine, ISSN 1546-170X, 2002, Volume 8, Issue 10, pp. 1089 - 1097
The intracellular signaling mechanisms that specify tissue-specific responses to the interleukin-6 (IL-6) family of cytokines are not well understood. Here, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | HEPATIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | INTESTINAL INFLAMMATION | RESPONSES | INTERLEUKIN-6 FAMILY | COLITIS | IN-VIVO | DISEASE | CYTOKINE RECEPTORS | TRANSGENIC MICE | SIGNAL TRANSDUCER | Protein Tyrosine Phosphatase, Non-Receptor Type 11 | Membrane Glycoproteins - metabolism | Transcriptional Activation | Peptides - genetics | Neuropeptides | Protein Tyrosine Phosphatases - metabolism | Wound Healing | Antigens, CD - genetics | Antigens, CD - metabolism | Growth Substances - genetics | Peptides - metabolism | Digestive System Physiological Phenomena | Protein Phosphatase 2 | Interleukin-6 - metabolism | Cytokine Receptor gp130 | Colon - pathology | Interleukin-11 - metabolism | Mice, Transgenic | Spleen - cytology | Colon - metabolism | STAT1 Transcription Factor | Mice | Intestinal Mucosa - pathology | Intestinal Mucosa - metabolism | Homeostasis | Stomach Neoplasms - metabolism | Stomach Neoplasms - pathology | Stomach - metabolism | Adenoma - metabolism | DNA-Binding Proteins - metabolism | Muscle Proteins | Trefoil Factor-3 | Trefoil Factor-2 | Cell Line | Stomach - pathology | Gene Expression Regulation | Intracellular Signaling Peptides and Proteins | Membrane Glycoproteins - genetics | Proteins - genetics | Animals | Proteins - metabolism | Spleen - metabolism | Mucins | Stomach - cytology | Adenoma - pathology | Signal Transduction - physiology | Trans-Activators - metabolism | Growth Substances - metabolism | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Brain, behavior, and immunity, ISSN 0889-1591, 2015, Volume 44, pp. 221 - 234
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2003, Volume 278, Issue 44, pp. 42906 - 42912
Journal Article
PloS one, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e31469
Background: Several activities of the transmembrane form of TNF (memTNF) in immune responses to intracellular bacterial infection have been shown to be... 
TUMOR-NECROSIS-FACTOR | SECRETED TNF | CALMETTE-GUERIN INFECTION | TRANSMEMBRANE TNF | LIVER-INJURY | CELL-MEDIATED-IMMUNITY | IN-VIVO | BIOLOGY | MICE | MYCOBACTERIAL INFECTION | FACTOR-ALPHA | Tumor Necrosis Factor-alpha - metabolism | Mycobacterium bovis - immunology | Receptors, Tumor Necrosis Factor, Type II - chemistry | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - metabolism | Disease Resistance - immunology | Interferon-gamma - metabolism | Receptors, Tumor Necrosis Factor, Type II - metabolism | Cell Membrane - metabolism | Mycobacterium bovis - pathogenicity | Macrophages - immunology | Macrophages - microbiology | Intracellular Space - immunology | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Solubility | Tuberculosis - veterinary | Gene Knock-In Techniques | Tuberculosis - immunology | Macrophages - metabolism | Animals | Intracellular Space - microbiology | Interferon-gamma - immunology | Intracellular Space - metabolism | Chemokines - metabolism | Mice | Nitric Oxide - metabolism | Nitric Oxide Synthase Type II - metabolism | Infection | Immune response | Bacterial infections | Tumor necrosis factor | Genetic engineering | Comparative analysis | Health aspects | Tumor necrosis factor receptors | Phosphorylation | Liver | Arthritis | Infections | Macrophages | Antiinfectives and antibacterials | Receptors | Microorganisms | Immunology | Transgenic animals | Rodents | Bone marrow | Bacteria | Tumor necrosis factor-TNF | Spleen | NF-κB protein | Cytokines | Dermatology | Immune response (cell-mediated) | BCG | Transgenic mice | Inflammation | Nitric-oxide synthase | Studies | Herbal medicine | Pathology | Tuberculosis | Lungs | γ-Interferon | Regulatory mechanisms (biology) | Ligands | In vivo methods and tests | Interferon | Mutation | Chemokines | Tumors | Apoptosis
Journal Article
Amino acids, ISSN 1438-2199, 2016, Volume 49, Issue 1, pp. 161 - 172
Journal Article