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Blood, ISSN 0006-4971, 02/2015, Volume 125, Issue 9, pp. 1427 - 1434
The impairment of cytotoxic activity of lymphocytes disturbs immune surveillance and leads to the development of hemophagocytic lymphohistiocytic syndrome... 
ACTIVATION | DISRUPTION | GENE | SUSCEPTIBILITY | FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | PERFORIN | MUTATIONS | IDENTIFICATION | HEMATOLOGY | CD8(+) T-CELLS | EXHAUSTION | Lymphocytic choriomeningitis virus - immunology | Spleen - virology | T-Lymphocytes, Cytotoxic - immunology | Lymphocytic Choriomeningitis - virology | Lymphohistiocytosis, Hemophagocytic - pathology | Cell Proliferation | Spleen - immunology | Killer Cells, Natural - virology | Lymphocytic Choriomeningitis - pathology | Interferon-gamma - secretion | Mice, Inbred C57BL | Cells, Cultured | Killer Cells, Natural - pathology | Lymphocytic Choriomeningitis - immunology | Viral Load | Lymphohistiocytosis, Hemophagocytic - virology | Animals | Killer Cells, Natural - immunology | Mice | Cytotoxicity, Immunologic - immunology | Spleen - pathology | Lymphohistiocytosis, Hemophagocytic - immunology | Killer Cells, Natural/immunology | Lymphocytic Choriomeningitis/pathology | Lymphohistiocytosis, Hemophagocytic/virology | Lymphocytic Choriomeningitis/immunology | Innate immunity | Lymphohistiocytosis, Hemophagocytic/immunology | Killer Cells, Natural/pathology | Spleen/pathology | Life Sciences | Immunology | Lymphocytic Choriomeningitis/virology | Spleen/virology | Lymphocytic choriomeningitis virus/immunology | Spleen/immunology | Killer Cells, Natural/virology | Lymphohistiocytosis, Hemophagocytic/pathology | Cytotoxicity, Immunologic/immunology | T-Lymphocytes, Cytotoxic/immunology | Interferon-gamma/secretion
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2016, Volume 6, Issue 1, p. 23513
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47542
Background: Mortality in the first months of antiretroviral therapy (ART) is a significant clinical problem in sub-Saharan Africa. To date, no post-mortem... 
AUTOPSY | RECONSTITUTION INFLAMMATORY SYNDROME | SUB-SAHARAN AFRICA | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | HIV-POSITIVE PATIENTS | DISEASE | ADULTS | COHORT | EARLY MORTALITY | PATHOLOGY | Liver - virology | Tuberculosis, Pulmonary - microbiology | Liver - pathology | Kidney - pathology | Humans | Middle Aged | Male | Tuberculosis, Pulmonary - drug therapy | Bacterial Infections - virology | Liver - drug effects | Autopsy | HIV Infections - mortality | Lymph Nodes - drug effects | Bacterial Infections - microbiology | Bone Marrow - drug effects | Bone Marrow - virology | Kidney - drug effects | Bacterial Infections - drug therapy | HIV Infections - virology | Tuberculosis, Pulmonary - pathology | Tuberculosis, Pulmonary - mortality | Bacterial Infections - pathology | Lung - drug effects | Biopsy, Needle | Kidney - virology | Bacterial Infections - mortality | Mycobacterium tuberculosis - growth & development | Lymph Nodes - pathology | Mycobacterium tuberculosis - drug effects | Cause of Death | HIV - drug effects | Lung - virology | Immune Reconstitution Inflammatory Syndrome - virology | HIV Infections - pathology | Adult | Female | Skin - virology | Skin - pathology | Lung - pathology | South Africa - epidemiology | Lymph Nodes - virology | Immune Reconstitution Inflammatory Syndrome - mortality | HIV - growth & development | Antiretroviral Therapy, Highly Active | Immune Reconstitution Inflammatory Syndrome - pathology | Bone Marrow - pathology | Immune Reconstitution Inflammatory Syndrome - drug therapy | HIV Infections - drug therapy | Skin - drug effects | Tuberculosis, Pulmonary - virology | Antiviral agents | Bacterial infections | Mycobacterium tuberculosis | Dosage and administration | Diagnosis | Research | Drug therapy | Risk factors | Reproductive health | Health sciences | Therapy | Laboratories | Liver | Systematic review | Infections | Cerebrospinal fluid | Drug resistance | Lymph nodes | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Human immunodeficiency virus--HIV | Bone marrow | Bacteria | Ultrasound | Spleen | Autopsies | Kidneys | Internal medicine | Mortality | Immune reconstitution | Inflammation | Patients | Antiretroviral therapy | Medicine | Hospitals | Tuberculosis | Infectious diseases | Lungs | Biopsy | Death | Fatalities | Adults | Skin | Bone | Kidney transplantation | Lymph | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2017, Volume 13, Issue 5, p. e1006378
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2015, Volume 195, Issue 9, pp. 4378 - 4386
Studies of influenza-specific immune responses in humans have largely assessed systemic responses involving serum Ab and peripheral blood T cell responses.... 
Spleen - immunology | Humans | Influenza A Virus, H1N1 Subtype - physiology | Macaca mulatta - immunology | Interferon-gamma - metabolism | T-Lymphocytes - virology | Antigens, CD - metabolism | Host-Pathogen Interactions - immunology | Lectins, C-Type - metabolism | T-Lymphocytes - metabolism | Time Factors | Bone Marrow - metabolism | Integrin alpha Chains - immunology | B-Lymphocytes - virology | CD8-Positive T-Lymphocytes - metabolism | B-Lymphocytes - metabolism | Bone Marrow - virology | Antigens, Differentiation, T-Lymphocyte - metabolism | Lymph Nodes - metabolism | Lymph Nodes - immunology | B-Lymphocytes - immunology | T-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - immunology | Orthomyxoviridae Infections - virology | Influenza A Virus, H1N1 Subtype - immunology | Spleen - virology | Antigens, CD - immunology | Bone Marrow - immunology | Age Factors | Lectins, C-Type - immunology | Macaca mulatta - virology | Lung - virology | Macaca mulatta - metabolism | Interleukin-2 - immunology | Lung - metabolism | Immunologic Memory - immunology | Interleukin-2 - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Orthomyxoviridae Infections - metabolism | Cells, Cultured | Integrin alpha Chains - metabolism | Lymph Nodes - virology | Mediastinum - virology | Animals | Spleen - metabolism | CD8-Positive T-Lymphocytes - virology | Interferon-gamma - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology | Infectious Disease and Host Response
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 12/2017, Volume 23, Issue 12, pp. 2038 - 2041
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 04/2013, Volume 19, Issue 4, pp. 534 - 541
We characterized the complete genome of a novel dog circovirus (DogCV) from the liver of a dog with severe hemorrhagic gastroenteritis, vasculitis, and... 
PORCINE CIRCOVIRUS | PIGS | DIAGNOSIS | INFECTIOUS DISEASES | DISEASE | CANINE CALICIVIRUS | IMMUNOLOGY | MULTISYSTEMIC WASTING SYNDROME | COMPLETE NUCLEOTIDE-SEQUENCE | TYPE-2 | DISCOVERY | VIRUSES | Liver - virology | Spleen - virology | Dog Diseases - epidemiology | Vasculitis - veterinary | Circoviridae Infections - veterinary | Liver - pathology | Lymph Nodes - pathology | Vasculitis - epidemiology | Humans | DNA, Viral - isolation & purification | Diarrhea - epidemiology | Male | Vasculitis - virology | Phylogeny | Gastrointestinal Hemorrhage - epidemiology | Vasculitis - complications | Feces - virology | In Situ Hybridization | Gastrointestinal Hemorrhage - veterinary | Circovirus - genetics | Female | Spleen - pathology | Diarrhea - complications | Dog Diseases - virology | Genome, Viral | Circoviridae Infections - complications | California - epidemiology | Circoviridae Infections - virology | Diarrhea - virology | Diarrhea - veterinary | Lymph Nodes - virology | Circovirus - isolation & purification | Gastrointestinal Hemorrhage - complications | Animals | Polymerase Chain Reaction - veterinary | Circoviridae Infections - epidemiology | Dogs | DNA, Viral - genetics | Circovirus - classification | DNA, Viral - classification | Gastrointestinal Hemorrhage - virology | Infection | Vasculitis | Gastroenteritis | Genomics | Diarrhea | Genomes | Health aspects | canine vascular disease | viruses | circovirus | vasculitis | deep sequencing | dogs | necrotizing vasculitis | hemorrhagic gastroenteritis | Research | granulomatous lymphadenitis
Journal Article
Journal Article
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