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1. Pathology in practice
by Scruggs, Jennifer L and Weber, Katherine A
Journal of the American Veterinary Medical Association, ISSN 0003-1488, 12/2017, Volume 251, Issue 12, pp. 1391 - 1393
VETERINARY SCIENCES | VISCERAL LEISHMANIASIS | DOGS | Afghanistan | Diagnosis, Differential | Leishmania infantum | Nose - pathology | Ear, External - pathology | Male | Leishmaniasis, Visceral - pathology | Dog Diseases - pathology | Macrophages - parasitology | Spleen - parasitology | Travel | Leishmaniasis, Visceral - veterinary | Animals | Biopsy, Fine-Needle - veterinary | Dogs | Splenomegaly - veterinary | Foot - pathology | Dog Diseases - diagnosis | Spleen - pathology | Leishmaniasis, Visceral - diagnosis
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2. Full Text Negative role of colony-stimulating factor-1 in macrophage T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice
by Lenda, DM and Stanley, ER and Kelley, VR
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2004, Volume 173, Issue 7, pp. 4744 - 4754
Inflammation in the kidney and other tissues (lung, and salivary and lacrimal glands) is characteristic of MRL-Fas(lpr) mice with features of lupus.... 
MRL-LPR MICE | OP OP MOUSE | M-CSF | IFN-GAMMA | MRL/LPR MICE | OSTEOPETROTIC OP/OP MICE | MESANGIAL CELLS | ACUTE-RENAL-FAILURE | TNF-ALPHA | IMMUNOLOGY | SYSTEMIC AUTOIMMUNITY | Salivary Glands - immunology | Leukocytes - pathology | Salivary Glands - pathology | Spleen - immunology | Apoptosis - genetics | Cell Migration Inhibition | Cytokines - physiology | Lymphatic Diseases - genetics | Mice, Inbred MRL lpr | Chemokines - antagonists & inhibitors | B-Lymphocytes - pathology | Kidney Tubules - pathology | Growth Inhibitors - genetics | Macrophage Colony-Stimulating Factor - genetics | Lupus Nephritis - pathology | Epithelium - pathology | Macrophages - pathology | Splenomegaly - genetics | Complement C3 - metabolism | Macrophage Activation - immunology | Lymphatic Diseases - immunology | Splenomegaly - immunology | Chemokines - physiology | Lacrimal Apparatus - immunology | Splenomegaly - prevention & control | Mice, Transgenic | Lupus Nephritis - immunology | Kidney Glomerulus - pathology | Down-Regulation - genetics | Mice, Knockout | Immunoglobulin Isotypes - biosynthesis | B-Lymphocytes - immunology | Growth Inhibitors - physiology | Lymphatic Diseases - pathology | T-Lymphocytes - immunology | Mice | Kidney Glomerulus - immunology | Immunoglobulin G - metabolism | Lupus Nephritis - prevention & control | Bone Marrow - immunology | Leukopenia - immunology | Macrophage Activation - genetics | Leukopenia - genetics | Macrophage Colony-Stimulating Factor - deficiency | Epithelium - immunology | Kidney Glomerulus - metabolism | T-Lymphocytes - pathology | Lacrimal Apparatus - pathology | Spleen - pathology | Macrophages - immunology | Skin - pathology | Skin - immunology | Kidney Tubules - immunology | Severity of Illness Index | Lung - pathology | Lupus Nephritis - genetics | Growth Inhibitors - deficiency | Mice, Inbred C57BL | Lymphatic Diseases - prevention & control | Leukopenia - pathology | Mice, Inbred C3H | Animals | Apoptosis - immunology | Down-Regulation - immunology | Bone Marrow - pathology | Cytokines - antagonists & inhibitors | Macrophage Colony-Stimulating Factor - physiology | Lung - immunology
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3. Full Text Role of blood and bone marrow examination in the diagnosis of mature lymphoid neoplasms in patients presenting with isolated splenomegaly
by Sreedharanunni, Sreejesh and Singh Sachdeva, Man Updesh and Malhotra, Pankaj and Ahluwalia, Jasmina and Naseem, Shano and Prakash, Gaurav and Khadwal, Alka and Sharma, Prashant and Kumar, Narender and Varma, Neelam and Varma, Subhash and Das, Reena
Hematology, ISSN 1024-5332, 10/2015, Volume 20, Issue 9, pp. 530 - 537
Objectives Mature lymphoid neoplasms presenting with 'prominent splenomegaly without significant lymphadenopathy' are uncommon and pose unique diagnostic... 
Splenomegaly | Immunophenotype | Mature lymphoid neoplasms | Splenic lymphoma | MANAGEMENT | MALIGNANT-LYMPHOMA | DISORDERS | SPLENIC MARGINAL-ZONE | INFILTRATION | B-CELL LYMPHOMA | SPLEEN | CHRONIC LYMPHOCYTIC-LEUKEMIA | NON-HODGKINS-LYMPHOMA | HEMATOLOGY | CLINICOPATHOLOGICAL FEATURES | Immunohistochemistry | Pancytopenia - pathology | Humans | Middle Aged | Lymphoma, Follicular - diagnosis | Lymphoma, Mantle-Cell - pathology | Lymphocytosis - pathology | Male | Splenomegaly - pathology | Lymphoma, Mantle-Cell - diagnosis | Splenomegaly - diagnosis | Flow Cytometry | Lymphatic Diseases - diagnosis | Lymphocytosis - diagnosis | Adult | Female | Lymphoma, B-Cell, Marginal Zone - pathology | Retrospective Studies | Leukemia, Hairy Cell - pathology | Diagnosis, Differential | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphoma, Follicular - pathology | Pancytopenia - diagnosis | Immunophenotyping | Splenic Neoplasms - diagnosis | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Leukemia, Hairy Cell - diagnosis | Leukocytes, Mononuclear - pathology | Lymphoma, Large B-Cell, Diffuse - diagnosis | Lymphoma, B-Cell, Marginal Zone - diagnosis | Splenic Neoplasms - pathology | Bone Marrow - pathology | Adolescent | Lymphatic Diseases - pathology | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis
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4. Full Text Hairy cell leukemia: Uncommon clinical features, unusual sites of involvement and some rare associations
by Tadmor, Tamar and Polliack, Aaron
Best Practice & Research: Clinical Haematology, ISSN 1521-6926, 2015, Volume 28, Issue 4, pp. 193 - 199
Abstract Unusual clinical manifestations and associations with auto-immunity or other systemic disorders are uncommon clinical features of hairy cell leukemia... 
Hematology, Oncology and Palliative Medicine | Rare manifestations | Clinical features | Hairy cell leukemia (HCL) | DIAGNOSIS | LYMPHADENOPATHY | COMPLICATIONS | HEMATOLOGY | Bone and Bones - pathology | Liver - pathology | Lymph Nodes - pathology | Humans | Male | Behcet Syndrome - pathology | Splenomegaly - pathology | Antiphospholipid Syndrome - complications | Thrombocytopenia - complications | Splenomegaly - complications | Splenomegaly - diagnosis | Liver - immunology | Anemia, Hemolytic, Autoimmune - pathology | Lymphatic Diseases - diagnosis | Anemia, Hemolytic, Autoimmune - diagnosis | Female | B-Lymphocytes - pathology | Leukemia, Hairy Cell - pathology | Skin - pathology | Skin - immunology | Leukemia, Hairy Cell - immunology | Antiphospholipid Syndrome - diagnosis | Lymphatic Diseases - immunology | Splenomegaly - immunology | Thrombocytopenia - immunology | Behcet Syndrome - complications | Lymphatic Diseases - complications | Anemia, Hemolytic, Autoimmune - complications | Lymph Nodes - immunology | Thrombocytopenia - pathology | Leukemia, Hairy Cell - diagnosis | Antiphospholipid Syndrome - immunology | B-Lymphocytes - drug effects | Leukemia, Hairy Cell - complications | Antiphospholipid Syndrome - pathology | Anemia, Hemolytic, Autoimmune - immunology | Sex Factors | Lymphatic Diseases - pathology | Thrombocytopenia - diagnosis | Behcet Syndrome - diagnosis | Bone and Bones - immunology | Behcet Syndrome - immunology | Leukemia, Hairy cell
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5. Full Text Chronic myeloid leukemia patients in Tunisia: epidemiology and outcome in the imatinib era (a multicentric experience)
by Ben Lakhal, Raihane and Ghedira, Hela and Bellaaj, Hatem and Ben Youssef, Yosra and Menif, Samia and Manai, Zeineb and Bedoui, Manel and Lakhal, Amel and M’Sadek, Fehmi and Elloumi, Moez and Khélif, Abderrahmane and Ben Romdhane, Neila and Laatiri, Mohamed Adnène and Ben Othmen, Tarek and Meddeb, Balkis
Annals of Hematology, ISSN 0939-5555, 4/2018, Volume 97, Issue 4, pp. 597 - 604
Data are limited in developing countries regarding the clinicopathologic features and response to therapy of chronic myeloid leukemia (CML) in the era of... 
Imatinib | Survey | CML | Medicine & Public Health | Hematology | Oncology | Management | Tunisia | Clinical practice | SURVIVAL | INTERFERON | CHRONIC-PHASE | RECOMMENDATIONS | HEMATOLOGY | EUROPEAN-LEUKEMIANET | Prognosis | Follow-Up Studies | Humans | Leukemia, Myeloid, Chronic-Phase - pathology | Middle Aged | Child, Preschool | Male | Antineoplastic Agents - therapeutic use | Practice Patterns, Physicians | Protein Kinase Inhibitors - adverse effects | Splenomegaly - pathology | Leukemia, Myeloid, Accelerated Phase - epidemiology | Young Adult | Imatinib Mesylate - therapeutic use | Leukemia, Myeloid, Accelerated Phase - pathology | Antineoplastic Agents - adverse effects | Imatinib Mesylate - adverse effects | Leukemia, Myeloid, Accelerated Phase - diagnosis | Splenomegaly - etiology | Aged, 80 and over | Adult | Female | Retrospective Studies | Child | Leukemia, Myeloid, Accelerated Phase - drug therapy | Leukemia, Myeloid, Chronic-Phase - drug therapy | Splenomegaly - prevention & control | Leukemia, Myeloid, Chronic-Phase - diagnosis | Leukemia, Myeloid, Chronic-Phase - epidemiology | Tumor Burden - drug effects | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Aged | Tunisia - epidemiology | Antimitotic agents | Chronic myeloid leukemia | Antineoplastic agents | Epidemiology | Patient outcomes | Analysis | Multivariate analysis | Medical prognosis | Leukemia | Developing countries--LDCs | Index Medicus | Tumor Burden/drug effects | Leukemia, Myeloid, Chronic-Phase/epidemiology | Splenomegaly/prevention & control | Leukemia, Myeloid, Accelerated Phase/epidemiology | Antineoplastic Agents/therapeutic use | Splenomegaly/pathology | Life Sciences | Leukemia, Myeloid, Chronic-Phase/pathology | Antineoplastic Agents/adverse effects | Tunisia/epidemiology | Leukemia, Myeloid, Accelerated Phase/pathology | Leukemia, Myeloid, Chronic-Phase/diagnosis | Leukemia, Myeloid, Chronic-Phase/drug therapy | Splenomegaly/etiology | Human health and pathology | Protein Kinase Inhibitors/adverse effects | Leukemia, Myeloid, Accelerated Phase/drug therapy | Imatinib Mesylate/therapeutic use | Leukemia, Myeloid, Accelerated Phase/diagnosis | Protein Kinase Inhibitors/therapeutic use | Imatinib Mesylate/adverse effects
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6. Full Text Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model
by Li, Li and Piloto, Obdulio and Nguyen, Ho Bao and Greenberg, Kathleen and Takamiya, Kogo and Racke, Frederick and Huso, David and Small, Donald
Blood, ISSN 0006-4971, 04/2008, Volume 111, Issue 7, pp. 3849 - 3858
Constitutive activation of FMS-like tyrosine kinase 3 (FLT3) by internal tandem duplication (ITD) mutations is one of the most common molecular alterations... 
PROGENITOR CELLS | DENDRITIC CELLS | INDUCE | CONSTITUTIVE ACTIVATION | 32D CELLS | HEMATOPOIETIC STEM-CELLS | GENE-EXPRESSION | TYROSINE KINASE INHIBITOR | BONE-MARROW-CELLS | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | Leukocytes, Mononuclear - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Myelopoiesis - genetics | Hematopoietic Stem Cells - pathology | Cell Membrane - genetics | Myeloproliferative Disorders - pathology | Splenomegaly - pathology | Myeloproliferative Disorders - genetics | fms-Like Tyrosine Kinase 3 - genetics | Leukocytosis - metabolism | Time Factors | Bone Marrow - metabolism | Myeloproliferative Disorders - metabolism | Cell Membrane - pathology | Cell Membrane - metabolism | Colony-Forming Units Assay | Spleen - pathology | Disease Models, Animal | Leukocytosis - pathology | Splenomegaly - genetics | Leukemia, Myeloid, Acute - pathology | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | Protein Structure, Tertiary - genetics | Splenomegaly - metabolism | fms-Like Tyrosine Kinase 3 - metabolism | Leukocytes, Mononuclear - pathology | Animals | Spleen - metabolism | Bone Marrow - pathology | Mice | Mutation | Leukocytosis - genetics | Leukemia, Myeloid, Acute - genetics | Neoplasia
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7. Full Text The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice
by Cui, Shuaiying and Lim, Kim-Chew and Shi, Lihong and Lee, Mary and Jearawiriyapaisarn, Natee and Myers, Greggory and Campbell, Andrew and Harro, David and Iwase, Shigeki and Trievel, Raymond C and Rivers, Angela and DeSimone, Joseph and Lavelle, Donald and Saunthararajah, Yogen and Engel, James Douglas
Blood, ISSN 0006-4971, 07/2015, Volume 126, Issue 3, pp. 386 - 396
Inhibition of lysine-specific demethylase 1 (LSD1) has been shown to induce fetal hemoglobin (HbF) levels in cultured human erythroid cells in vitro. Here we... 
NUCLEAR RECEPTORS TR2 | GAMMA-GLOBIN | DECITABINE | ERYTHROPOIESIS | HYDROXYUREA | ANEMIA | INDUCTION | HEMATOLOGY | ORAL SODIUM PHENYLBUTYRATE | HISTONE DEMETHYLATION | CHILDREN | Anemia, Sickle Cell - pathology | Fetal Hemoglobin - biosynthesis | Rhodamines - pharmacology | Histone Demethylases - antagonists & inhibitors | Humans | Splenomegaly - pathology | Promoter Regions, Genetic - genetics | Anemia, Sickle Cell - prevention & control | Immunoenzyme Techniques | Flow Cytometry | Splenomegaly - blood | Real-Time Polymerase Chain Reaction | Disease Models, Animal | RNA, Messenger - genetics | Cells, Cultured | Splenomegaly - prevention & control | Thiophenes - pharmacology | Fetal Hemoglobin - drug effects | Reverse Transcriptase Polymerase Chain Reaction | beta-Globins - genetics | Blotting, Western | Animals | beta-Globins - metabolism | Mice | Anemia, Sickle Cell - blood | Spiro Compounds - pharmacology | 103 | Red Cells, Iron, and Erythropoiesis
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8. Full Text JAK2 V617F‐positive acute myeloid leukaemia (AML): a comparison between de novo AML and secondary AML transformed from an underlying myeloproliferative neoplasm. A study from the Bone Marrow Pathology Group
by Aynardi, Jason and Manur, Rashmi and Hess, Paul R and Chekol, Seble and Morrissette, Jennifer J. D and Babushok, Daria and Hexner, Elizabeth and Rogers, Heesun J and Hsi, Eric D and Margolskee, Elizabeth and Orazi, Attilio and Hasserjian, Robert and Bagg, Adam
British Journal of Haematology, ISSN 0007-1048, 07/2018, Volume 182, Issue 1, pp. 78 - 85
The JAK2 V617F mutation is characteristic of most Philadelphia chromosome‐negative myeloproliferative neoplasms (MPNs) and occurs rarely in de novo acute... 
JAK2 | acute myeloid leukaemia | V617F | myeloproliferative | JAK2 V617F | HEMATOLOGY | PROGNOSIS | MUTATION | Medicine, Experimental | Medical research | Analysis | Tumors | Splenomegaly | Transformation | Leukemia | Histology | Patients | Neoplasms | Philadelphia chromosome | Chemotherapy | Janus kinase 2 | DNA methylation | Bone marrow | Megakaryocytes | Mutation | Methylation | Deoxyribonucleic acid--DNA
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9. Full Text Chronic myelomonocytic leukemia masquerading as cutaneous indeterminate dendritic cell tumor: Expanding the spectrum of skin lesions in chronic myelomonocytic leukemia
by Loghavi, Sanam and Curry, Jonathan L and Garcia‐Manero, Guillermo and Patel, Keyur P and Xu, Jie and Khoury, Joseph D and Torres‐Cabala, Carlos A and Nagarajan, Priyadharsini and Aung, Phyu P and Gibson, Bernard R and Goodwin, Brandon P and Kelly, Brent C and Korivi, Brinda R and Medeiros, L. Jeffrey and Prieto, Victor G and Kantarjian, Hagop M and Bueso‐Ramos, Carlos E and Tetzlaff, Michael T
Journal of Cutaneous Pathology, ISSN 0303-6987, 12/2017, Volume 44, Issue 12, pp. 1075 - 1079
Chronic myelomonocytic leukemia (CMML) is a hematopoietic stem cell neoplasm exhibiting both myelodysplastic and myeloproliferative features. Cutaneous... 
cutaneous | KRAS | indeterminate cell | CMML | HISTIOCYTOSIS | PATHOLOGY | LANGERHANS | DERMATOLOGY | Skin Diseases - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Leukemia, Myelomonocytic, Chronic - genetics | Dendritic Cells - pathology | Hematopoietic Stem Cells - pathology | Male | Positron-Emission Tomography | Lymphoma, Non-Hodgkin - genetics | Skin Diseases - pathology | Splenomegaly - pathology | Splenomegaly - diagnostic imaging | Disease Progression | Lymphoma, Non-Hodgkin - pathology | Biopsy | Bone Marrow - pathology | Lymphoma, Non-Hodgkin - metabolism | Aged | Leukemia, Myelomonocytic, Chronic - pathology | Mutation | Leukemia, Myelomonocytic, Chronic - diagnostic imaging | Skin - pathology | Development and progression | Skin | Dendritic cells | Leukemia | Hematopoietic stem cells | Splenomegaly | Myelomonocytic leukemia | Vigilance | Transformation | Myeloid leukemia | Histiocytosis | Hemopoiesis | K-Ras protein | Chronic myelomonocytic leukemia | Stem cells | Skin diseases | Acute myeloid leukemia
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10. Full Text Compartment-Specific Remodeling of Splenic Micro-Architecture during Experimental Visceral Leishmaniasis
by Yurdakul, Pinar and Dalton, Jane and Beattie, Lynette and Brown, Najmeeyah and Erguven, Sibel and Maroof, Asher and Kaye, Paul M
American Journal of Pathology, The, ISSN 0002-9440, 2011, Volume 179, Issue 1, pp. 23 - 29
Progressive splenomegaly is a hallmark of visceral leishmaniasis in humans, canids, and rodents. In experimental murine visceral leishmaniasis, splenomegaly is... 
Pathology | RESERVOIR | DENDRITIC CELLS | ANGIOGENESIS | MACROPHAGES | INFLAMMATION | DEFICIENT | NEUTROPHILS | MICE | PATHOLOGY | DONOVANI INFECTION | Splenomegaly | Spleen - immunology | Dendritic Cells - immunology | Neovascularization, Pathologic | B-Lymphocytes - parasitology | Dendritic Cells - pathology | Leishmaniasis, Visceral - immunology | Monocytes - immunology | Immunoenzyme Techniques | Macrophages - parasitology | Neutrophils - parasitology | Flow Cytometry | Fibroblasts - parasitology | Mesocricetus | Monocytes - pathology | Antigens, Ly - metabolism | Female | Monocytes - parasitology | Leishmaniasis, Visceral - parasitology | B-Lymphocytes - pathology | Spleen - pathology | Macrophages - immunology | Neutrophils - pathology | Cricetinae | Dendritic Cells - parasitology | Macrophages - pathology | Mice, Inbred C57BL | Cells, Cultured | Neutrophils - immunology | Leishmania donovani - pathogenicity | Fibroblasts - pathology | Leishmaniasis, Visceral - pathology | Blotting, Western | Spleen - parasitology | Animals | B-Lymphocytes - immunology | Antibodies, Monoclonal - administration & dosage | Fibroblasts - immunology | Mice | Short Communication
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11. Full Text Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice
by Cattoretti, Giorgio and Pasqualucci, Laura and Ballon, Gianna and Tam, Wayne and Nandula, Subhadra V and Shen, Qiong and Mo, Tongwei and Murty, Vundavalli V and Dalla-Favera, Riccardo
Cancer Cell, ISSN 1535-6108, 2005, Volume 7, Issue 5, pp. 445 - 455
Diffuse large B cell lymphomas (DLBCL) derive from germinal center (GC) B cells and display chromosomal alterations deregulating the expression of BCL6, a... 
CHROMOSOMAL TRANSLOCATIONS | GERMINAL-CENTER FORMATION | SOMATIC HYPERMUTATION | ONCOLOGY | INFLAMMATION | NEGATIVE AUTOREGULATION | FINGER ENCODING GENE | TRANSCRIPTIONAL REPRESSION | NON-HODGKINS-LYMPHOMA | AFFECTING BAND 3Q27 | DIFFERENTIATION | Gene Expression - genetics | Germinal Center - chemistry | Humans | Splenomegaly - pathology | Lymphoma, B-Cell - genetics | Promoter Regions, Genetic - genetics | Lymphoma, Non-Hodgkin - pathology | Plasma Cells - pathology | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | Time Factors | Plasma Cells - metabolism | Plasma Cells - chemistry | Spleen - pathology | Disease Models, Animal | Genes, Immunoglobulin - genetics | Lymphoma, Large B-Cell, Diffuse - pathology | Mice, Inbred C57BL | Mice, Transgenic | Lymphoproliferative Disorders - genetics | Germinal Center - pathology | Lymphoma, Non-Hodgkin - genetics | DNA-Binding Proteins - genetics | Mice, Inbred Strains | Lymphoproliferative Disorders - pathology | Mice, Knockout | Spleen - chemistry | Hemagglutinins - genetics | Animals | Germinal Center - metabolism | Spleen - metabolism | Chromosome Aberrations | Lymphoma, B-Cell - pathology | Survival Analysis | Mice | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-6 | Analysis | Lymphomas
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12. Full Text Lenalidomide therapy in myelofibrosis with myeloid metaplasia
by Tefferi, Ayalew and Cortes, Jorge and Verstovsek, Srdan and Mesa, Ruben A and Thomas, Deborah and Lasho, Terra L and Hogan, William J and Litzow, Mark R and Allred, Jacob B and Jones, Dan and Byrne, Catriona and Zeldis, Jerome B and Ketterling, Rhett P and McClure, Rebecca F and Giles, Francis and Kantarjian, Hagop M
Blood, ISSN 0006-4971, 08/2006, Volume 108, Issue 4, pp. 1158 - 1164
We present results of 2 similarly designed but separate phase 2 studies involving single-agent lenalidomide (CC-5013, Revlimid) in a total of 68 patients with... 
MULTIPLE-MYELOMA | GROWTH-FACTOR-BETA | LOW-DOSE THALIDOMIDE | CC-5013 | MYELOPROLIFERATIVE-DISORDERS | ANGIOGENESIS | ANALOGS | MUTATION | CELL TRANSPLANTATION | MYELODYSPLASTIC-SYNDROMES | HEMATOLOGY | Humans | Male | Primary Myelofibrosis - pathology | Neovascularization, Pathologic - complications | Primary Myelofibrosis - blood | Thrombocytopenia - genetics | Thalidomide - analogs & derivatives | Anemia - genetics | Anemia - drug therapy | Anemia, Myelophthisic - genetics | Time Factors | Splenomegaly - blood | Neutropenia - blood | Thalidomide - adverse effects | Primary Myelofibrosis - complications | Splenomegaly - genetics | Administration, Oral | Anemia, Myelophthisic - pathology | Thrombocytopenia - chemically induced | Thalidomide - administration & dosage | Thrombocytopenia - pathology | Remission Induction | Neovascularization, Pathologic - drug therapy | Anemia, Myelophthisic - complications | Sequence Deletion | Splenomegaly - drug therapy | Anemia - blood | Anemia - pathology | Splenomegaly - pathology | Anemia, Myelophthisic - blood | Neovascularization, Pathologic - blood | Neovascularization, Pathologic - pathology | Janus Kinase 2 | Splenomegaly - complications | Protein-Tyrosine Kinases - genetics | Thrombocytopenia - drug therapy | Neutropenia - pathology | Adult | Female | Neutropenia - chemically induced | Neutropenia - genetics | Primary Myelofibrosis - drug therapy | Proto-Oncogene Proteins - genetics | Thrombocytopenia - blood | Anemia, Myelophthisic - drug therapy | Point Mutation | Anemia - complications | Primary Myelofibrosis - genetics | Platelet Count | Neovascularization, Pathologic - genetics | Aged | Hemoglobins - analysis
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13. Full Text TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
by Rickard, James A and Anderton, Holly and Etemadi, Nima and Nachbur, Ueli and Darding, Maurice and Peltzer, Nieves and Lalaoui, Najoua and Lawlor, Kate E and Vanyai, Hannah and Hall, Cathrine and Bankovacki, Aleks and Gangoda, Lahiru and Wong, Wendy W.ei-Lynn and Corbin, Jason and Huang, Chunzi and Mocarski, Edward S and Murphy, James M and Alexander, Warren S and Voss, Anne K and Vaux, David L and Kaiser, William J and Walczak, Henning and Silke, John
eLife, ISSN 2050-084X, 2014, Volume 3
SHARPIN regulates immune signaling and contributes to full transcriptional activity and prevention of cell death in response to TNF in vitro. The inactivating... 
mouse | stem cells | cell biology | dermatitis | inflammation | developmental biology | apoptosis | TNF signaling | LUBAC | ubiquitin | APOPTOSIS | CHRONIC PROLIFERATIVE DERMATITIS | RIP3 KINASE | BIOLOGY | MIXED LINEAGE KINASE | CHAIN ASSEMBLY COMPLEX | DOMAIN-LIKE | LYMPHOTOXIN-ALPHA | NLRP3 INFLAMMASOME | KAPPA-B ACTIVITY | CUTTING EDGE | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Liver - pathology | Nerve Tissue Proteins - deficiency | Caspase 3 - metabolism | Caspase 8 - metabolism | Spleen - drug effects | Receptors, Tumor Necrosis Factor, Type I - metabolism | Inflammation - metabolism | Ubiquitination - drug effects | Liver - drug effects | Receptors, Tumor Necrosis Factor, Type II - metabolism | Cytoprotection - drug effects | Cell Death - drug effects | Spleen - pathology | Fibroblasts - metabolism | Mice, Inbred C57BL | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Fibroblasts - pathology | Receptors, Interleukin-1 - metabolism | Nerve Tissue Proteins - metabolism | Dermatitis - pathology | Tumor Necrosis Factor-alpha - pharmacology | Keratinocytes - pathology | Macrophages - metabolism | Animals | Keratinocytes - drug effects | Keratinocytes - metabolism | Fibroblasts - drug effects | Myeloid Cells - metabolism | Heterozygote | Macrophages - drug effects | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Myeloid Cells - pathology | Chronic Disease | Dermatitis - metabolism | Tumor necrosis factor receptors | Splenomegaly | Transcription | Liver | Lethality | Kinases | Dermatitis | Inflammatory diseases | Proteins | Genotype & phenotype | Immunology | Clonal deletion | Interleukin 1 | Tumor necrosis factor-TNF | Peyer's patches | Medical research | Cytokines | Glycerol | Caspase | Inflammation | Heterozygosity | Caspase-8 | Tumor necrosis factor | Cell death | Cancer | Apoptosis
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14. Full Text Measurement of Spleen Stiffness to Evaluate Portal Hypertension and the Presence of Esophageal Varices in Patients With HCV-Related Cirrhosis
by Colecchia, Antonio and Montrone, Lucia and Scaioli, Eleonora and Bacchi–Reggiani, Maria Letizia and Colli, Agostino and Casazza, Giovanni and Schiumerini, Ramona and Turco, Laura and Di Biase, Anna Rita and Mazzella, Giuseppe and Marzi, Luca and Arena, Umberto and Pinzani, Massimo and Festi, Davide
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 3, pp. 646 - 654
Background & Aims The hepatic vein pressure gradient (HVPG) is the standard used to determine the degree of portal hypertension (PH) and an important... 
Gastroenterology and Hepatology | Splenomegaly | Diagnosis | Liver Disease | Prognostic Factor | LIVER STIFFNESS | VALIDATION | COUNT/SPLEEN DIAMETER RATIO | CLASSIFICATION | ENLARGEMENT | FIBROSCAN | ACCURACY | TRANSIENT ELASTOGRAPHY | VENOUS-PRESSURE GRADIENT | GASTROENTEROLOGY & HEPATOLOGY | Liver - virology | Predictive Value of Tests | Liver - pathology | Hypertension, Portal - physiopathology | Prognosis | Humans | Middle Aged | Male | Splenomegaly - pathology | Hypertension, Portal - diagnosis | Splenomegaly - diagnosis | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Hepatitis C - complications | Splenomegaly - virology | Spleen - pathology | Esophageal and Gastric Varices - diagnosis | Hypertension, Portal - virology | Blood Pressure Determination | Severity of Illness Index | Hypertension, Portal - pathology | Endoscopy, Gastrointestinal | Linear Models | Esophageal and Gastric Varices - pathology | Chi-Square Distribution | Liver - blood supply | Liver Cirrhosis - virology | Platelet Count | Portal Pressure | Biopsy | Italy | Aged | Esophageal and Gastric Varices - virology | Elasticity Imaging Techniques | Measurement | Liver cirrhosis | Venous pressure | Varicose veins | Esophageal varices | Medical research | Analysis | Liver | Medicine, Experimental | Hepatitis C virus | Hepatitis C
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