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Journal Article
by Evans, David M and Spencer, Chris C. A and Pointon, Jennifer J and Su, Zhan and Harvey, David and Kochan, Grazyna and Opperman, Udo and Dilthey, Alexander and Pirinen, Matti and Stone, Millicent A and Appleton, Louise and Moutsianis, Loukas and Leslie, Stephen and Wordsworth, Tom and Kenna, Tony J and Karaderi, Tugce and Thomas, Gethin P and Ward, Michael M and Weisman, Michael H and Farrar, Claire and Bradbury, Linda A and Danoy, Patrick and Inman, Robert D and Maksymowych, Walter and Gladman, Dafna and Rahman, Proton and Morgan, Ann and Marzo-Ortega, Helena and Bowness, Paul and Gaffney, Karl and Gaston, J. S. Hill and Smith, Malcolm and Bruges-Armas, Jacome and Couto, Ana-Rita and Sorrentino, Rosa and Paladini, Fabiana and Ferreira, Manuel A and Xu, Huji and Liu, Yu and Jiang, Lei and Lopez-Larrea, Carlos and Díaz-Peña, Roberto and Lóepez-Vázquez, Antonio and Zayats, Tetyana and Band, Gavin and Bellenguez, Céline and Blackburn, Hannah and Blackwell, Jenefer M and Bramon, Elvira and Bumpstead, Suzannah J and Casas, Juan P and Corvin, Aiden and Craddock, Nicholas and Deloukas, Panos and Dronov, Serge and Duncanson, Audrey and Edkins, Sarah and Freeman, Colin and Gillman, Matthew and Gray, Emma and Gwilliam, Rhian and Hammond, Naomi and Hunt, Sarah E and Jankowski, Janusz and Jayakumar, Alagurevathi and Langford, Cordelia and Liddle, Jennifer and Markus, Hugh S and Mathew, Christopher G and McCann, Owen T and McCarthy, Mark I and Palmer, Colin N. A and Peltonen, Leena and Plomin, Robert and Potter, Simon C and Rautanen, Anna and Ravindrarajah, Radhi and Ricketts, Michelle and Samani, Nilesh and Sawcer, Stephen J and Strange, Amy and Trembath, Richard C and Viswanathan, Ananth C and Waller, Matthew and Weston, Paul and Whittaker, Pamela and Widaa, Sara and Wood, Nicholas W and McVean, Gilean and Reveille, John D and Wordsworth, B. Paul and Brown, Matthew A and Donnelly, Peter and Australo-Anglo-Amer Spondyloarthri and Wellcome Trust Case Control Consor and Spondyloarthrit Res Consortium Can and Wellcome Trust Case Control Consortium 2 (WTCCC2) and Spondyloarthritis Research Consortium of Canada (SPARCC) and Australo-Anglo-American Spondyloarthritis Consortium (TASC) and The Australo-Anglo-American Spondyloarthritis Consortium (TASC) and the Wellcome Trust Case Control Consortium 2 (WTCCC2)
Nature Genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 761 - 767
Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the spine and pelvis that occurs in approximately 5 out of 1,000... 
POPULATION | CELLS | INFLAMMATORY-BOWEL-DISEASE | GENETIC ASSOCIATION | GENETICS & HEREDITY | RISK | TRIMS PRECURSORS | AMINOPEPTIDASE | HLA | PROMOTES | GENOME-WIDE ASSOCIATION | Receptors, Prostaglandin E, EP4 Subtype - genetics | Interleukin-12 Subunit p40 - genetics | Aminopeptidases - genetics | Genome-Wide Association Study | Meta-Analysis as Topic | Peptide Fragments - metabolism | Disease Susceptibility | Spondylitis, Ankylosing - genetics | Membrane Proteins - genetics | Minor Histocompatibility Antigens | Humans | European Continental Ancestry Group | Receptors, Tumor Necrosis Factor, Type I - genetics | Spondylitis, Ankylosing - metabolism | Case-Control Studies | CARD Signaling Adaptor Proteins - genetics | Latent TGF-beta Binding Proteins - genetics | Receptors, Peptide | CD8-Positive T-Lymphocytes - metabolism | Core Binding Factor Alpha 3 Subunit - genetics | Polymorphism, Genetic - genetics | Aminopeptidases - metabolism | HLA-B27 Antigen - genetics | Histocompatibility antigens | HLA histocompatibility antigens | Physiological aspects | Disease susceptibility | Genetic aspects | Research | Single nucleotide polymorphisms | Ankylosing spondylitis | Risk factors | Inflammatory bowel disease | Medical research | Biomedical research | Lymphocytes | Immunotherapy | Quality control | Genomes | Gene expression | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
Journal Article
Journal Article
Pharmacological Reviews, ISSN 0031-6997, 02/2015, Volume 67, Issue 2, pp. 280 - 309
The human immune system involves highly complex and coordinated processes in which small proteins named cytokines play a key role. Cytokines have been... 
TUMOR-NECROSIS-FACTOR | MODIFYING ANTIRHEUMATIC DRUGS | COLONY-STIMULATING FACTOR | JUVENILE IDIOPATHIC ARTHRITIS | SEVERE PLAQUE PSORIASIS | ANTI-TNF THERAPY | PHARMACOLOGY & PHARMACY | PLACEBO-CONTROLLED TRIAL | LONG-TERM TREATMENT | ACTIVE ANKYLOSING-SPONDYLITIS | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | Drugs, Investigational - adverse effects | Interleukin-6 - antagonists & inhibitors | Humans | Crohn Disease - metabolism | Drugs, Investigational - therapeutic use | Spondylitis, Ankylosing - immunology | Arthritis, Rheumatoid - metabolism | Anti-Inflammatory Agents - adverse effects | Arthritis, Rheumatoid - drug therapy | Arthritis, Psoriatic - drug therapy | Psoriasis - metabolism | Anti-Inflammatory Agents - therapeutic use | Antirheumatic Agents - adverse effects | Interleukin-1 - antagonists & inhibitors | Interleukin-6 - metabolism | Arthritis, Psoriatic - metabolism | Antirheumatic Agents - therapeutic use | Psoriasis - immunology | Interleukin-1 - metabolism | Molecular Targeted Therapy - adverse effects | Psoriasis - drug therapy | Cytokines - metabolism | Spondylitis, Ankylosing - drug therapy | Tumor Necrosis Factors - metabolism | Spondylitis, Ankylosing - metabolism | Crohn Disease - immunology | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Arthritis, Psoriatic - immunology | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Models, Biological | Crohn Disease - drug therapy | Cytokines - antagonists & inhibitors | Arthritis, Rheumatoid - immunology | Tumor Necrosis Factors - antagonists & inhibitors
Journal Article
Journal Article
Clinical Rheumatology, ISSN 0770-3198, 6/2015, Volume 34, Issue 6, pp. 1009 - 1018
Journal Article