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1. Full Text Mite allergen–specific IgE is detectable in bronchial secretions of patients with nonatopic asthma and correlates with mucosal expression of periostin
by Mouthuy, Jonathan, PhD and Viart, Sophie, PhD and Ladjemi, Maha Z., PhD and Detry, Bruno, MSc and Henket, Monique, MSc and Bachert, Claus, MD, PhD and Louis, Renaud, MD, PhD and Pilette, Charles, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 6, pp. 1685 - 1688.e2
Allergy and Immunology | Skin Tests | Asthma - physiopathology | Humans | Middle Aged | Male | Cell Adhesion Molecules - immunology | Bronchi - immunology | Eosinophils - immunology | Immunoglobulin E - blood | Forced Expiratory Volume | Antigens, Dermatophagoides - immunology | Sputum - immunology | Animals | Immunoglobulin E - immunology | Allergens - immunology | Asthma - blood | Epithelial Cells - immunology | Respiratory Mucosa - immunology | Asthma - immunology | Adult | Female | Aged | Leukocyte Count | Eosinophils - cytology | Immunoglobulin E | Allergens | Asthma | Immunoglobulins | Gene expression | Rodents | Allergies | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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2. Full Text Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma
by Smith, Steven G., PhD and Gugilla, Akash, BSc and Mukherjee, Manali, PhD and Merim, Kayla, BSc and Irshad, Anam, BSc and Tang, Wei, MD and Kinoshita, Takashi, MD and Watson, Brittany, BSc and Oliveria, John-Paul, BSc and Comeau, Mike, PhD and O'Byrne, Paul M., MD and Gauvreau, Gail M., PhD and Sehmi, Roma, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1594 - 1602
Allergy and Immunology | Hematopoietic progenitor cells | thymic stromal lymphopoietin | asthma | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Interleukin-1 Receptor-Like 1 Protein | Sputum - cytology | Eosinophils - drug effects | Humans | Middle Aged | Hematopoietic Stem Cells - pathology | Interleukin-13 - immunology | Male | Interleukin-7 Receptor alpha Subunit - immunology | Interleukin-5 - genetics | Eosinophils - immunology | Forced Expiratory Volume | Interleukins - genetics | Hematopoietic Stem Cells - immunology | Interleukin-13 - genetics | Interleukin-13 Receptor alpha1 Subunit - immunology | Sputum - immunology | Chemokine CXCL12 - genetics | Interleukins - immunology | Methacholine Chloride - pharmacology | Asthma - immunology | Adult | Eosinophils - pathology | Interleukin-7 Receptor alpha Subunit - genetics | Cytokines - genetics | Receptors, Cytokine - genetics | Chemokine CXCL12 - immunology | Cytokines - immunology | Hematopoietic Stem Cells - drug effects | Interleukin-33 | Gene Expression Regulation | Administration, Inhalation | Immunity, Innate | Receptors, Cell Surface - immunology | Asthma - genetics | Interleukin-13 Receptor alpha1 Subunit - genetics | Interleukin-5 - immunology | Cell Movement - drug effects | Receptors, Cytokine - immunology | Allergens - pharmacology | Primary Cell Culture | Asthma - pathology | Receptors, Cell Surface - genetics | Care and treatment | Asthma | Studies | Flow cytometry | Airway management | Cytokines | Pathogenesis | Migration | Family medical history | Allergies | Index Medicus | Abridged Index Medicus
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3. Full Text CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation
by Allakhverdi, Zoulfia, PhD and Comeau, Michael R., BSc and Smith, Dirk E., MSc and Toy, Dean, MSc and Endam, Leandra Mfuna, MSc and Desrosiers, Martin, MD and Liu, Yong-Jun, MD, PhD and Howie, Karen J., MSc and Denburg, Judah A., MD and Gauvreau, Gail M., PhD and Delespesse, Guy, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2009, Volume 123, Issue 2, pp. 472 - 478.e1
Allergy and Immunology | Blood CD34 + cells | TSLP | airway epithelial cells | asthma | chemokines | rhinosinusitis | allergen inhalation challenge | IL-33 | T H2 cytokines | Blood CD34 | cells | 2 cytokines | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Medical sciences | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Hematopoietic Stem Cells - drug effects | Asthma - metabolism | Antigens, CD34 - metabolism | Interleukin-33 | Humans | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Sputum - metabolism | Allergens - metabolism | Cell Differentiation - immunology | Hematopoietic Stem Cells - immunology | Inflammation - metabolism | Sputum - immunology | Allergens - immunology | Antigens, CD34 - immunology | Interleukins - immunology | Asthma - immunology | Receptors, Cytokine - immunology | Receptors, Cytokine - metabolism | Cytokines - biosynthesis | Cytokines - immunology | Lymphatic system | Pathogenesis | Stem cells | Skin | Gene expression | Allergies | Chemokines | Immune system | Index Medicus | Abridged Index Medicus
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4. Full Text Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms
by Hinks, Timothy S.C., MD and Zhou, Xiaoying, PhD and Staples, Karl J., PhD and Dimitrov, Borislav D., MD and Manta, Alexander, PhD and Petrossian, Tanya, PhD and Lum, Pek Y., PhD and Smith, Caroline G., RN and Ward, Jon A., BSc and Howarth, Peter H., MD and Walls, Andrew F., PhD and Gadola, Stephan D., MD and Djukanović, Ratko, MD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 323 - 333
Allergy and Immunology | T lymphocytes | phenotype | mucosal-associated invariant T-cell | regulatory T | endotype | cytokines | mast cells | TH17 | Asthma | TH2 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Sputum - cytology | Anti-Asthmatic Agents - therapeutic use | Humans | Middle Aged | Interleukin-13 - immunology | Male | Receptors, Antigen, T-Cell, gamma-delta - genetics | Th2 Cells - immunology | Adrenal Cortex Hormones - therapeutic use | Case-Control Studies | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Interleukin-13 - genetics | Basophils - pathology | Asthma - immunology | Basophils - immunology | Adult | Female | Bronchoalveolar Lavage Fluid - cytology | Th2 Cells - pathology | Th17 Cells - pathology | Adaptive Immunity | Severity of Illness Index | Mast Cells - immunology | Gene Expression | Receptors, Antigen, T-Cell, gamma-delta - immunology | Immunity, Innate | Asthma - drug therapy | Asthma - genetics | Sputum - chemistry | Mast Cells - pathology | Adolescent | Bayes Theorem | Th17 Cells - immunology | Aged | Bronchoalveolar Lavage Fluid - chemistry | Asthma - pathology | T cells | Studies | Biomedical research | Disease | Cytokines | Biopsy | Lymphocytes | Software | Methods | Index Medicus | Abridged Index Medicus | FOXP3, Forkhead box protein 3 | Treg, Regulatory T | Tc, Cytotoxic T | eNO, Exhaled nitric oxide | BAL, Bronchoalveolar lavage | MAIT, Mucosal-associated invariant T | ACQ, Asthma Control Questionnaire | Asthma and Lower Airway Disease | TDA, Topological data analysis | IQR, Interquartile range | GINA, Global Initiative for Asthma | BNA, Bayesian network analysis | ICS, Inhaled corticosteroid
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5. Full Text Coexpression of type 2 immune targets in sputum-derived epithelial and dendritic cells from asthmatic subjects
by Bleck, Bertram, PhD and Kazeros, Angeliki, MD and Bakal, Keren, MD and Garcia-Medina, Lymaris, MD and Adams, Alexandra, MD and Liu, Mengling, PhD and Lee, Richard A., MD and Tse, Doris B., PhD and Chiu, Amanda, BA and Grunig, Gabriele, DVM, PhD and Egan, John P., MD and Reibman, Joan, MD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 619 - 627.e5
Allergy and Immunology | thymic stromal lymphopoietin | dendritic cells | OX40 ligand | bronchial epithelial cells | sputum | IL-33 | CCL17 | Asthma | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Sputum - cytology | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Epithelial Cells - metabolism | OX40 Ligand - genetics | Dendritic Cells - immunology | Humans | Middle Aged | Interleukin-17 - immunology | Dendritic Cells - pathology | Chemokine CCL17 - genetics | Male | Gene Expression Profiling | Interleukin-33 - immunology | Case-Control Studies | Signal Transduction - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | B7-2 Antigen - immunology | Dendritic Cells - metabolism | Phosphoprotein Phosphatases - immunology | Antigens, CD1 - immunology | Gene Expression | B7-1 Antigen - immunology | Cell Communication | Interleukin-17 - genetics | Epithelial Cells - pathology | Signal Transduction - genetics | Asthma - genetics | Interleukin-33 - genetics | OX40 Ligand - immunology | Phosphoprotein Phosphatases - genetics | Epithelial Cells - immunology | Antigens, CD1 - genetics | Asthma - pathology | Dendritic cells | Studies | Human subjects | Ethnicity | Cytokines | Laboratories | Inflammation | Index Medicus | Abridged Index Medicus
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6. Full Text Human asthma phenotypes: from the clinic, to cytokines, and back again
by Bhakta, Nirav R and Woodruff, Prescott G
Immunological reviews, ISSN 0105-2896, 07/2011, Volume 242, Issue 1, pp. 220 - 232
cytokine | phenotype | asthma | clinical trials | biomarker | Clinical trials | Biomarker | Phenotype | Cytokine | Asthma | Life Sciences & Biomedicine | Immunology | Science & Technology | Sputum - cytology | Asthma - metabolism | Humans | Interleukin-13 - immunology | Th2 Cells - immunology | Adrenal Cortex Hormones - therapeutic use | Eosinophils - immunology | Nitric Oxide - analysis | Airway Remodeling - immunology | Signal Transduction - immunology | Sputum - immunology | Allergens - immunology | Asthma - immunology | Adult | Asthma - classification | Child | Asthma - physiopathology | Biomarkers - analysis | Neutrophils - immunology | Administration, Inhalation | Inflammation - immunology | Immunity, Innate | Asthma - drug therapy | Th2 Cells - metabolism | Mice, Knockout | Randomized Controlled Trials as Topic | Animals | Mice | Nitrogen oxide | Inflammation | Cytokines | Analysis | Index Medicus | Animal models | Reviews | Nitric oxide | biomarkers | Helper cells | Sputum | Data processing | Respiratory tract diseases | Lymphocytes T
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7. Full Text Similar activation state of neutrophils in sputum of asthma patients irrespective of sputum eosinophilia
by Tak, T and Hilvering, B and Tesselaar, Kiki and Koenderman, L
Clinical and experimental immunology, ISSN 0009-9104, 11/2015, Volume 182, Issue 2, pp. 204 - 212
lung | Research Support, Non-U.S. Gov't | neutrophils | Journal Article | cell surface molecules | Cell surface molecules | Lung | Neutrophils | Life Sciences & Biomedicine | Immunology | Science & Technology | Antigens, CD - immunology | Eosinophils - metabolism | Eosinophilia - blood | Humans | Middle Aged | Lectins, C-Type - immunology | Male | Eosinophils - immunology | Antigens, CD - metabolism | L-Selectin - metabolism | Lectins, C-Type - metabolism | L-Selectin - immunology | Sputum - immunology | Flow Cytometry | Asthma - blood | Asthma - immunology | Adult | Female | Leukocyte Count | Neutrophils - metabolism | Principal Component Analysis | Neutrophil Activation - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | CD11b Antigen - immunology | Neutrophils - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | Cell Survival - immunology | B7-H1 Antigen - immunology | Sputum - metabolism | B7-H1 Antigen - metabolism | Eosinophilia - immunology | Asthma - complications | Aged | Eosinophilia - complications | CD11b Antigen - metabolism | Eosinophilia | Analysis | Asthma | Index Medicus | Translational
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8. Full Text Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma
by Rossios, Christos, PhD and Pavlidis, Stelios, PhD and Hoda, Uruj, MBBS and Kuo, Chih-Hsi, MBBS and Wiegman, Coen, PhD and Russell, Kirsty, PhD and Sun, Kai, PhD and Loza, Matthew J., PhD and Baribaud, Frederic, PhD and Durham, Andrew L., PhD and Ojo, Oluwaseun, PhD and Lutter, Rene, PhD and Rowe, Anthony, PhD and Bansal, Aruna, PhD and Auffray, Charles, PhD and Sousa, Ana, PhD and Corfield, Julie, MSc and Djukanovic, Ratko, MD and Guo, Yike, PhD and Sterk, Peter J., MD and Chung, Kian Fan, MD and Adcock, Ian M., PhD and Unbiased Biomarkers for the Prediction of Respiratory Diseases Outcomes (U-BIOPRED) Consortia Project Team and Unbiased Biomarkers Prediction Res
Journal of allergy and clinical immunology, ISSN 0091-6749, 2017, Volume 141, Issue 2, pp. 560 - 570
Allergy and Immunology | C-reactive protein | inflammasome | exhaled nitric oxide | Severe asthma | eosinophil | IL-1β | neutrophil | IL-1α | IL-33 receptor | TH2 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Receptors, Interleukin-1 - immunology | Humans | Middle Aged | Neutrophils - immunology | Male | Gene Expression Profiling | Th2 Cells - immunology | Eosinophils - immunology | Sputum - immunology | Animals | Up-Regulation - immunology | Asthma - immunology | Adult | Female | Eosinophils - pathology | Mice | Asthma - pathology | Th2 Cells - pathology | Neutrophils - pathology | Genes | Lymphocytes T | Leucine | Interleukin 1 receptors | Proteins | Cell activation | Interleukin 1 | Respiratory tract diseases | Binding | Data analysis | Oligomerization | Leukocytes (eosinophilic) | Neutrophils | Leukocytes (neutrophilic) | Inflammation | Interleukin 13 | Gene expression | Patients | Eosinophilia | Allergies | Asthma | Pyrin protein | DNA microarrays | Biopsy | Sputum | Neutrophilia | Biomarkers | Software | Smoking | Index Medicus | Abridged Index Medicus
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