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Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6046, pp. 1157 - 1160
Journal Article
by Lawrence, Michael S and Sougnez, Carrie and Lichtenstein, Lee and Cibulskis, Kristian and Lander, Eric and Gabriel, Stacey B and Getz, Gad and Ally, Adrian and Balasundaram, Miruna and Birol, Inanc and Bowlby, Reanne and Brooks, Denise and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Dean and Chu, Andy and Dhalla, Noreen and Guin, Ranabir and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Li, Haiyan I and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Robertson, A. Gordon and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Thiessen, Nina and Wong, Tina and Protopopov, Alexei and Santoso, Netty and Lee, Semin and Parfenov, Michael and Zhang, Jianhua and Mahadeshwar, Harshad S and Tang, Jiabin and Ren, Xiaojia and Seth, Sahil and Haseley, Psalm and Zeng, Dong and Yang, Lixing and Xu, Andrew W and Song, Xingzhi and Pantazi, Angeliki and Bristow, Christopher A and Hadjipanayis, Angela and Seidman, Jonathan and Chin, Lynda and Park, Peter J and Kucherlapati, Raju and Akbani, Rehan and Casasent, Tod and Liu, Wenbin and Lu, Yiling and Mills, Gordon and Motter, Thomas and Weinstein, John and Diao, Lixia and Wang, Jing and Hong Fan, You and Liu, Jinze and Wang, Kai and Auman, J. Todd and Balu, Saianand and Bodenheimer, Thomas and Buda, Elizabeth and Hayes, D. Neil and Hoadley, Katherine A and Hoyle, Alan P and Jefferys, Stuart R and Jones, Corbin D and Kimes, Patrick K and Liu, Yufeng and Marron, J.S and Meng, Shaowu and Mieczkowski, Piotr A and Mose, Lisle E and Parker, Joel S and Perou, Charles M and Prins, Jan F and Roach, Jeffrey and Shi, Yan and Simons, Janae V and Singh, Darshan and Soloway, Matthew G and Tan, Donghui and Veluvolu, Umadevi and Walter, Vonn and Waring, Scot and Wilkerson, Matthew D and Wu, Junyuan and Zhao, Ni and Cherniack, Andrew D and Hammerman, Peter S and Tward, Aaron D and Pedamallu, Chandra Sekhar and Saksena, Gordon and ... and Canc Genome Atlas Network and Cancer Genome Atlas Network and The Cancer Genome Atlas Network
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7536, pp. 576 - 582
Journal Article
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6046, pp. 1154 - 1157
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. To explore the genetic origins of this cancer, we used whole-exome... 
Head | REPORTS | Medical genetics | Nonsense | Tumor suppressor genes | Genetic mutation | Sequencing | Human genetics | Oncogenes | Tumors | Cancer | PROGNOSTIC IMPLICATIONS | GENE | PATHWAY | STATISTICS | MULTIDISCIPLINARY SCIENCES | OROPHARYNGEAL CANCER | TUMOR-SUPPRESSOR | HUMAN-PAPILLOMAVIRUS | LEUKEMIA | P53 | F-Box-WD Repeat-Containing Protein 7 | Head and Neck Neoplasms - virology | Oligonucleotide Array Sequence Analysis | Exons | Humans | Carcinoma - virology | Receptor, Notch1 - chemistry | Neoplasms, Squamous Cell - virology | Mutation, Missense | INDEL Mutation | Genes, p53 | Squamous Cell Carcinoma of Head and Neck | Neoplasms, Squamous Cell - drug therapy | Cell Cycle Proteins - genetics | Papillomavirus Infections - virology | Genes, Tumor Suppressor | Carcinoma - drug therapy | Head and Neck Neoplasms - drug therapy | Gene Dosage | Codon, Nonsense | Papillomaviridae - isolation & purification | Sequence Analysis, DNA | Carcinoma, Squamous Cell | Tobacco | Neoplasms, Squamous Cell - genetics | Carcinoma - genetics | Head and Neck Neoplasms - genetics | Mutation | Receptor, Notch1 - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Smoking | Squamous cell carcinoma | Genetic aspects | Research | Diagnosis | Gene mutations | Genetics | Head & neck cancer | Risk factors | Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2016, Volume 34, Issue 32, pp. 3838 - 3845
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54736 - e54736
Head and neck squamous cell carcinoma (HNSCC) represents more than 5% of all cancers diagnosed annually in United States and around the world. Despite advances... 
HSP90 | IN-VITRO | ACTIVATED PROTEIN-KINASE | CANCER CHEMOPREVENTIVE ACTIVITY | MULTIDISCIPLINARY SCIENCES | GROWTH | DOWN-REGULATION | AKT INHIBITOR | AMPK ACTIVATION | CERAMIDE | CONTRIBUTES | AMP-Activated Protein Kinases - metabolism | Apoptosis - drug effects | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Rotenone - analogs & derivatives | Antineoplastic Agents - administration & dosage | Autophagy | Ceramides - biosynthesis | Head and Neck Neoplasms - metabolism | Antineoplastic Agents - toxicity | Squamous Cell Carcinoma of Head and Neck | Rotenone - pharmacology | Rotenone - toxicity | Female | Antineoplastic Agents - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Tumor Cells, Cultured | Proto-Oncogene Proteins c-akt - metabolism | Rotenone - administration & dosage | Survivin | Cyclin-Dependent Kinase 4 - metabolism | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Fluorouracil - pharmacology | Mice | Heat shock proteins | Chemotherapy | Squamous cell carcinoma | Protein kinases | Cancer | Apoptosis | Reproductive health | Laboratories | Colorectal cancer | Otolaryngology | AKT protein | Kinases | AMP-activated protein kinase | Cancer therapies | Cyclin-dependent kinase 4 | Proteins | Cyclin-dependent kinase | Signal transduction | Xenografts | Ceramide | Neck | Enzymes | Immunoglobulins | AMP | Dermatology | Melanoma | Breast cancer | Disease control | Signaling | Cell death | Head and neck cancer | Phagocytosis | Heat shock | Index Medicus
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 07/2017, Volume 77, Issue 13, pp. 3540 - 3550
Antibody targeting of the immune checkpoint receptor PD1 produces therapeutic activity in a variety of solid tumors, but most patients exhibit partial or... 
BREAST-CANCER | BIOMARKERS | ANTI-PD-1 THERAPY | PEMBROLIZUMAB | ONCOLOGY | CLINICAL ONCOLOGY/COLLEGE | RECOMMENDATIONS | SENSITIVITY | MECHANISMS | TUMORS | AMERICAN SOCIETY | Gene Expression - drug effects | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Lung Neoplasms - pathology | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Squamous Cell Carcinoma of Head and Neck | Melanoma - genetics | Gene Expression - immunology | Aged, 80 and over | Adult | Female | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Non-Small-Cell Lung - genetics | Head and Neck Neoplasms - drug therapy | Gene Expression Profiling - methods | Melanoma - pathology | Head and Neck Neoplasms - pathology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Carcinoma, Squamous Cell - drug therapy | Melanoma - immunology | Melanoma - drug therapy | Nivolumab | Head and Neck Neoplasms - genetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | PD-1 protein | CD8 antigen | Lung | Antibodies | Activation | Lymphocytes T | Killer cells | Cell activation | Lymphocytes | Bioindicators | Neck | Natural killer cells | Signatures | Squamous cell carcinoma | Head | Immune response | Small cell lung carcinoma | Tumor-infiltrating lymphocytes | Melanoma | Lung carcinoma | Gene expression | Ribonucleic acid--RNA | Patients | CD4 antigen | Immune systems | Immune checkpoint | Reproducibility | PD-L1 protein | Biomarkers | Head and neck cancer | Interferon | Solid tumors | Cancer | Tumors | Index Medicus
Journal Article
Annals of oncology : official journal of the European Society for Medical Oncology, ISSN 0923-7534, 07/2017, Volume 28, Issue 7, pp. 1605 - 1611
Journal Article
Head & Neck, ISSN 1043-3074, 07/2016, Volume 38, Issue 7, pp. 1074 - 1084
Journal Article