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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2724 - 13
Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that... 
TGF-BETA | MELANOMA | THERAPY | MEMORY | CANCER REGRESSION | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | PD-1 | EXPRESSION | EXHAUSTION | ANTIGEN | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Adenocarcinoma of Lung - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Squamous Cell Carcinoma of Head and Neck - pathology | Ovarian Neoplasms - pathology | Transcriptome | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Squamous Cell Carcinoma of Head and Neck - mortality | Ovarian Neoplasms - mortality | Antigens, CD - genetics | Squamous Cell Carcinoma of Head and Neck - immunology | Ovarian Neoplasms - genetics | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Carcinoma, Squamous Cell - mortality | Melanoma - genetics | Integrin alpha Chains - immunology | Female | Adenocarcinoma of Lung - immunology | Apyrase - immunology | Immunophenotyping | Melanoma - pathology | Carcinoma, Squamous Cell - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8 Antigens - immunology | Squamous Cell Carcinoma of Head and Neck - genetics | Lymphocytes, Tumor-Infiltrating - pathology | Melanoma - immunology | Apyrase - genetics | CD8 Antigens - genetics | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Melanoma - mortality | Ovarian Neoplasms - immunology | Head | Phenotypes | Tumor cells | CD8 antigen | T cell receptors | Lymphocytes T | Patients | Metastases | T-cell receptor | CD103 antigen | Major histocompatibility complex | Lymphocytes | Immunotherapy | Head and neck cancer | Solid tumors | Cancer | Tumors | BASIC BIOLOGICAL SCIENCES
Journal Article
International Journal of Cancer, ISSN 0020-7136, 05/2018, Volume 142, Issue 9, pp. 1911 - 1925
Tumor cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface, where it can be recognized by pre‐activated NK cells. In... 
SCCHN | prognostic biomarker | Hsp70 | NK cells | IHC | retrospective trial | MEMBRANE EXPRESSION | UNITED-STATES | NATURAL-KILLER-CELLS | SEVERE COMBINED IMMUNODEFICIENCY | SHOCK PROTEINS | MOLECULAR CHAPERONES | MARKER EXPRESSION | HUMAN-PAPILLOMAVIRUS | ONCOLOGY | OROPHARYNGEAL CANCER | POSTOPERATIVE RADIOCHEMOTHERAPY | Immunohistochemistry | Squamous Cell Carcinoma of Head and Neck - metabolism | Head and Neck Neoplasms - virology | Prognosis | Humans | Middle Aged | DNA, Viral - metabolism | Head and Neck Neoplasms - therapy | Tumor Suppressor Protein p53 - metabolism | Male | Squamous Cell Carcinoma of Head and Neck - immunology | Head and Neck Neoplasms - metabolism | Squamous Cell Carcinoma of Head and Neck - virology | HSP70 Heat-Shock Proteins - metabolism | Head and Neck Neoplasms - immunology | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Killer Cells, Natural - immunology | Female | Retrospective Studies | Squamous Cell Carcinoma of Head and Neck - therapy | Neoplasm Staging | Human papillomavirus 16 - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Squamous cell carcinoma | Care and treatment | Relapse | Killer cells | Oncology, Experimental | Radiation | Heat shock proteins | Research | Tumor proteins | Cancer | Diseases | Lymphocyte receptors | Tumor cells | p53 Protein | Hsp70 protein | Paraffin | Tissues | Survival | Patients | Cell surface | Cisplatin | Metastases | Consortia | Surgery | Medical prognosis | Neck | CD56 antigen | Indicators | Deoxyribonucleic acid--DNA | Tumors | Heat shock | Tumor Markers and Signatures
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3220 - 13
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 01/2018, Volume 16, Issue 1, pp. 90 - 102
Journal Article
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 7/2019, Volume 68, Issue 7, pp. 1133 - 1141
Advanced oral squamous cell carcinomas (OSCC) have limited therapeutic options. Although immune therapies are emerging as a potentially effective alternative... 
Chemotherapy | Immunology | Medicine & Public Health | Vaccination | Oncology | Cancer Research | Oral squamous cell carcinoma | Carcinogenesis | 4NQO model | A 2A R inhibition | HEAD | DENDRITIC CELLS | ANGIOGENESIS | IMMUNOTHERAPY FACTS | ADENOSINE | IMMUNOLOGY | IDENTIFICATION | RESPONSES | ONCOLOGY | REGULATORY T-CELLS | A(2A)R inhibition | SUPPRESSOR-CELLS | EXPRESSION | Immunotherapy - methods | Triazines - therapeutic use | Squamous Cell Carcinoma of Head and Neck - pathology | Neoplasms, Experimental - chemically induced | Squamous Cell Carcinoma of Head and Neck - immunology | Neoplasms, Experimental - pathology | Cancer Vaccines - therapeutic use | Mouth Neoplasms - chemically induced | Vaccines, Subunit - therapeutic use | Neoplasms, Experimental - immunology | Female | Triazoles - therapeutic use | 4-Nitroquinoline-1-oxide - toxicity | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Treatment Outcome | Mouth Neoplasms - therapy | Mouth Neoplasms - immunology | Animals | Cisplatin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Squamous Cell Carcinoma of Head and Neck - chemically induced | Mouth Neoplasms - pathology | Combined Modality Therapy - methods | Mice | Squamous Cell Carcinoma of Head and Neck - therapy | Medical colleges | Squamous cell carcinoma | Analysis | Development and progression | T cells | Health aspects | Antigenic determinants | Cancer | Oral carcinoma | Immunoregulation | CD8 antigen | Combined vaccines | Lymphocytes T | Cisplatin | Index Medicus
Journal Article
Radiation Oncology, ISSN 1748-717X, 11/2018, Volume 13, Issue 1, pp. 216 - 9
BackgroundA high neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation and together with the platelet-to-lymphocyte ratio (PLR) is... 
Head and neck | Platelet-to-lymphocyte ratio | Squamous cell carcinoma | Inflammation | Neutrophil-to-lymphocyte ratio | Toxicity | MORTALITY | TUMOR ANGIOGENESIS | PROGNOSTIC VALUE | DELINEATION | THERAPY | ONCOLOGY | COLORECTAL-CANCER | RELEVANCE | SQUAMOUS-CELL CARCINOMA | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Chemoradiotherapy - adverse effects | Chemoradiotherapy - methods | Prognosis | Humans | Middle Aged | Kaplan-Meier Estimate | Neutrophils | Proportional Hazards Models | Male | Squamous Cell Carcinoma of Head and Neck - mortality | Squamous Cell Carcinoma of Head and Neck - immunology | Biomarkers, Tumor - blood | Lymphocytes | Progression-Free Survival | Aged, 80 and over | Lymphocyte Count | Adult | Female | Aged | Retrospective Studies | Squamous Cell Carcinoma of Head and Neck - therapy | Biomarkers, Tumor - immunology | Measurement | Care and treatment | Usage | Physiological aspects | Head and neck cancer | Research | Radiotherapy | Colorectal cancer | Radiation | Cancer therapies | Hypopharynx | Human papillomavirus | Blood platelets | Larynx | Bioindicators | Toxic diseases | Pretreatment | Background radiation | Continuity (mathematics) | Head | Cell survival | Cytokines | Mortality | Oropharynx | Radiation therapy | Regression analysis | Patients | Survival | Oral cavity | Chemotherapy | Medical prognosis | Biomarkers | Head & neck cancer | Solid tumors | Cancer | Acute toxicity
Journal Article
by Yu, D and Qi, X M and Zhao, X and Liu, Y and Xue, K and Jin, C S and Wen, L J
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, ISSN 1673-0860, 09/2017, Volume 52, Issue 9, p. 717
T cell immune checkpoint pathways contribute to tumor immune escape. Many studies have shown that immune checkpoint is demonstrably correlated with tumor grade... 
Squamous Cell Carcinoma of Head and Neck - genetics | Prognosis | Tumor Escape - genetics | Humans | Immunotherapy | T-Lymphocytes - immunology | Squamous Cell Carcinoma of Head and Neck - therapy | Squamous Cell Carcinoma of Head and Neck - immunology | Tumor Escape - immunology
Journal Article