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by Cohen, Ezra E W and Soulières, Denis and Le Tourneau, Christophe and Dinis, José and Licitra, Lisa and Ahn, Myung-Ju and Soria, Ainara and Machiels, Jean-Pascal and Mach, Nicolas and Mehra, Ranee and Burtness, Barbara and Zhang, Pingye and Cheng, Jonathan and Swaby, Ramona F and Harrington, Kevin J and Acosta-Rivera, Mirelis and Adkins, Douglas R and Aghmesheh, Morteza and Ahn, Myung-Ju and Airoldi, Mario and Aleknavicius, Eduardas and Al-Farhat, Yousuf and Algazi, Alain P and Almokadem, Salah and Alyasova, Anna and Bauman, Jessica R and Benasso, Marco and Berrocal, Alfonso and Bray, Victoria and Burtness, Barbara Ann and Caponigro, Francesco and Castro, Ana and Cescon, Terrence P and Chan, Kelvin and Chaudhry, Arvind and Chauffert, Bruno and Cohen, Ezra and Csoszi, Tibor and De Boer, J.P and Delord, Jean-Pierre and Dietz, Andreas and Dinis, Jose and Dupuis, Charlotte and Digue, Laurence and Erfan, Jozsef and Escobar Alvarez, Yolanda and Evans, Mererid and Fidler, Mary Jo and Forster, Martin David and Friesland, Signe and Ganti, Apar K and Geoffrois, Lionnel and Grant, Cliona and Gruenwald, Viktor and Harrington, Kevin and Hoffmann, Thomas and Horvai, Geza and Inciura, Arturas and Jang, Raymond and Jankowska, Petra and Jimeno, Antonio and Joseph, Mano and Juarez Ramiro, Alejandro and Karaszewska, Boguslawa and Kawecki, Andrzej and Keilholz, Ulrich and Keller, Ulrich and Kim, Sung-Bae and Kocsis, Judit and Kotecki, Nuria and Kozloff, Mark F and Lambea, Julio and Landherr, Laszlo and Lantsukhay, Yuri and Lazarev, Sergey Alexandrovich and Lee, Lip Way and Le Tourneau, Christophe and Licitra, Lisa and Lifirenko, Igor Dmitrievich and Mach, Nicolas and Martincic, Danko and Matorin, Oleg Vladmirovhich and McGrath, Margaret and Machiels, Jean-Pascal and Mehra, Ranee and Misiukiewicz, Krzysztof and Morris, John C and Mufazalov, Fagim Fanisovich and Niu, Jiaxin and Pamoorthy Srinivasan, Devraj and Perez Segura, Pedro and Rauch, Daniel and Ribeiro, Maria Leonor and Rodriguez, Cristina and Rolland, Frederic and Russo, Antonio and Ruzsa, Agnes and Sanches, Frederico and Shin, Sang-Won and Shtiveland, Mikhail and ... and KEYNOTE-040 investigators and Keynote-040 Investigators
The Lancet, ISSN 0140-6736, 01/2019, Volume 393, Issue 10167, pp. 156 - 167
There are few effective treatment options for patients with recurrent or metastatic head-and-neck squamous cell carcinoma. Pembrolizumab showed antitumour... 
CRITERIA | TRIAL | MEDICINE, GENERAL & INTERNAL | NIVOLUMAB | CANCER | CHEMOTHERAPY | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Docetaxel - adverse effects | Humans | Middle Aged | Squamous Cell Carcinoma of Head and Neck - pathology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | Cetuximab - therapeutic use | Cetuximab - adverse effects | Docetaxel - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Squamous Cell Carcinoma of Head and Neck - drug therapy | Female | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Drug Administration Schedule | Head and Neck Neoplasms - drug therapy | Kaplan-Meier Estimate | Disease Progression | Head and Neck Neoplasms - pathology | Methotrexate - adverse effects | Squamous Cell Carcinoma of Head and Neck - secondary | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cetuximab - administration & dosage | Methotrexate - administration & dosage | Aged | Methotrexate | Squamous cell carcinoma | Metastasis | Therapy | Toxicity | Perforation | Clinical trials | Oncology | Cancer therapies | Metastases | Skin cancer | Anticancer properties | Pembrolizumab | Randomization | Motivation | Platinum | Neck | Safety | Medical treatment | Fatigue | Hypothyroidism | Survival | Patients | Chemotherapy | Interactive systems | Large intestine | Head and neck cancer | Ligands | Tumors
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 5, pp. 583 - 594
Journal Article
2011, 2 ed., ISBN 1441994637, 699
This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading... 
Head | Clinical & internal medicine | Other branches of medicine | Radiotherapy | Oncology | Medicine & Public Health | Surgical Oncology | Squamous cell carcinoma | Neck
eBook
CANCER RESEARCH, ISSN 0008-5472, 07/2017, Volume 77, Issue 13, pp. 3540 - 3550
Antibody targeting of the immune checkpoint receptor PD1 produces therapeutic activity in a variety of solid tumors, but most patients exhibit partial or... 
BREAST-CANCER | BIOMARKERS | ANTI-PD-1 THERAPY | PEMBROLIZUMAB | ONCOLOGY | CLINICAL ONCOLOGY/COLLEGE | RECOMMENDATIONS | SENSITIVITY | MECHANISMS | TUMORS | AMERICAN SOCIETY | Gene Expression - drug effects | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Lung Neoplasms - pathology | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Squamous Cell Carcinoma of Head and Neck | Melanoma - genetics | Gene Expression - immunology | Aged, 80 and over | Adult | Female | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Non-Small-Cell Lung - genetics | Head and Neck Neoplasms - drug therapy | Gene Expression Profiling - methods | Melanoma - pathology | Head and Neck Neoplasms - pathology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Carcinoma, Squamous Cell - drug therapy | Melanoma - immunology | Melanoma - drug therapy | Nivolumab | Head and Neck Neoplasms - genetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | PD-1 protein | CD8 antigen | Antibodies | Activation | Lymphocytes T | Killer cells | Cell activation | Lymphocytes | Natural killer cells | Signatures | Immune system | Squamous cell carcinoma | Head | Immune response | Small cell lung carcinoma | Tumor-infiltrating lymphocytes | Melanoma | Lung carcinoma | Gene expression | Ribonucleic acid--RNA | Patients | CD4 antigen | Immune checkpoint | Reproducibility | PD-L1 protein | Biomarkers | Head and neck cancer | Interferon | Solid tumors | Cancer | Tumors
Journal Article
by Lacas, Benjamin and Bourhis, Jean and Overgaard, Jens and Zhang, Qiang and Grégoire, Vincent and Nankivell, Matthew and Zackrisson, Björn and Szutkowski, Zbigniew and Suwiński, Rafał and Poulsen, Michael and O'Sullivan, Brian and Corvò, Renzo and Laskar, Sarbani Ghosh and Fallai, Carlo and Yamazaki, Hideya and Dobrowsky, Werner and Cho, Kwan Ho and Beadle, Beth and Langendijk, Johannes A and Viegas, Celia Maria Pais and Hay, John and Lotayef, Mohamed and Parmar, Mahesh K B and Aupérin, Anne and van Herpen, Carla and Maingon, Philippe and Trotti, Andy M and Grau, Cai and Pignon, Jean-Pierre and Blanchard, Pierre and Blanchard, Pierre and Bourhis, Jean and Lacas, Benjamin and Pignon, Jean Pierre and Bernier, Jacques and Le, Quynh-Thu and Overgaard, Jens and Parmar, Masheh KB and Trotti, Andy and Agarwal, Jai Prakash and Aupérin, Anne and Ang, Kian K and Awwad, Hassan K and Bacigalupo, Almalina and Bartelink, Harry and Benhamou, Ellen and Budach, Wilfried and Chitapanarux, Imjai and Cho, Kwan Ho and Collette, Laurence and Corvò, Renzo and Dani, Carla and Dische, Stanley and Dobrowsky, Werner and Denham, James W and Driessen, Chantal ML and Fallai, Carlo and Beadle, Beth and Laskar, Sarbani Ghosh and Ghoshal, Sushmita and Grau, Cai and Gregoire, Vincent and Hay, John H and van Herpen, Carla and Hliniak, Andrzej and Johansen, Jørgen and Kristiansen, Claus Andrup and Krstevska, Valentina and Langendijk, Johannes A and Lapeyre, Michel and Lotayef, Mohamed and Maciejewski, Boguslaw and Maingon, Philippe and Michalski, Wojciech and Moon, Sung Ho and Nilsson, Per and Olmi, Patrizia and Nankivell, Matthew and Nishiyama, Kinji and O'Sullivan, Brian and Parmar, Mahesh KB and Pignon, Jean-Pierre and Poulsen, Michael G and Ramadas, Kunnambath and Rishi, Anupam and Rosenthal, David I and Sanguineti, Giuseppe and Saunders, Michele I and Sire, Christian and Skladowski, Krzysztof and Souhami, Luis and Suwinski, Rafal and Szutkowski, Zbigniew and Tandon, Nitin and van Tinteren, Harm and Torri, Valter and Tripcony, Lee and Viegas, Celia Maria Pais and Waldron, John and Widder, Joachim and ... and MARCH Collaborative Group and MARCH Collaborative Grp and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
The Lancet Oncology, ISSN 1470-2045, 09/2017, Volume 18, Issue 9, pp. 1221 - 1237
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 84, Issue 5, pp. 1198 - 1205
Journal Article
2005, Current clinical oncology., ISBN 9781588294739, x, 358
Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with... 
Head | Squamous cell carcinoma | Treatment | Neck | Cancer | Clinical & internal medicine | Medicine & Public Health | Oncology
Book
The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 19, pp. 1856 - 1867
Journal Article