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Science, ISSN 0036-8075, 8/2008, Volume 321, Issue 5889, pp. 691 - 696
MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to... 
Receptors | Phenotypes | Transfection | Cytokines | HEK293 cells | Genes | Cell lines | Fibroblasts | Agonists | Reports | Children | MYD88-DEFICIENT MICE | HERPES-SIMPLEX-VIRUS | PROTECTIVE IMMUNITY | MYELOID DIFFERENTIATION FACTOR-88 | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | HUMORAL IMMUNITY | STAPHYLOCOCCUS-AUREUS | AERUGINOSA LUNG INFECTION | HOST RESPONSE | CUTTING EDGE | Humans | Child, Preschool | Male | Mutation, Missense | Bacterial Infections - genetics | Pneumococcal Infections - immunology | Bacterial Infections - immunology | Gene Deletion | Pneumococcal Infections - genetics | Female | Toll-Like Receptors - metabolism | Child | Staphylococcal Infections - genetics | Disease Susceptibility | Cytokines - metabolism | Signal Transduction | Staphylococcal Infections - immunology | Receptors, Interleukin-1 - immunology | Toll-Like Receptors - immunology | Myeloid Differentiation Factor 88 - genetics | Immunity, Innate | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Receptors, Interleukin-1 - metabolism | Animals | Myeloid Differentiation Factor 88 - deficiency | Adolescent | Mice | Myeloid Differentiation Factor 88 - metabolism | Cell Line, Transformed | Genetic aspects | Bacterial infections | Pediatrics | Bacteria | Biomedical research | Genetic disorders | Immunology | Index Medicus | Pneumococcal Infections | Life Sciences | Toll-Like Receptors | Bacterial Infections | Myeloid Differentiation Factor 88 | Bacteriology | Staphylococcal Infections | Microbiology and Parasitology | Pseudomonas Infections | Receptors, Interleukin-1
Journal Article
Journal of Infection and Chemotherapy, ISSN 1341-321X, 2012, Volume 18, Issue 2, pp. 228 - 240
Abstract Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has become a major concern worldwide. In the United States, ST8 CA-MRSA with... 
Hematology, Oncology and Palliative Medicine | ST8 CA-MRSA/J | Medicine & Public Health | Diversity | Comparative genomics | Infectious Diseases | Internal Medicine | Oncology | Evolution | Infections | Toxic shock syndrome toxin-1 (TSST-1) | Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) | MOLECULAR CHARACTERIZATION | STRAINS | INFECTIOUS DISEASES | BULLOUS IMPETIGO | EMERGENCE | VIRULENCE DETERMINANTS | USA300 CLONE | IN-VITRO | MRSA | SEQUENCE | PHARMACOLOGY & PHARMACY | EXPRESSION | Community-Acquired Infections - transmission | Japan - epidemiology | Virulence Factors - genetics | Community-Acquired Infections - epidemiology | Genomics | Humans | Middle Aged | Methicillin-Resistant Staphylococcus aureus - classification | Child, Preschool | Infant | Male | Genetic Variation | Microbial Sensitivity Tests | Soft Tissue Infections | Young Adult | Aged, 80 and over | Adult | Female | Staphylococcal Infections - microbiology | Child | Methicillin-Resistant Staphylococcus aureus - genetics | Communicable Diseases, Emerging - microbiology | Methicillin-Resistant Staphylococcus aureus - drug effects | Bacterial Proteins - genetics | Communicable Diseases, Emerging - epidemiology | Staphylococcal Infections - transmission | Staphylococcal Infections - epidemiology | Molecular Epidemiology | Adolescent | Aged | Anti-Bacterial Agents - pharmacology | Communicable Diseases, Emerging - transmission | Methicillin-Resistant Staphylococcus aureus - isolation & purification | Community-Acquired Infections - microbiology | Drug resistance in microorganisms | Pneumonia | Peptides | Staphylococcal infections | Genes | Arginine | Cross infection | Nosocomial infections | Bacterial genetics | Health aspects | Staphylococcus aureus | Public health | Bacterial pneumonia | Cloning | Abscess | Septic shock | Respiratory agents | Biological diversity | Anopheles | Disease transmission | Influenza | Genetic research | Skin | Colitis | Universities and colleges | Index Medicus | Mosaics | Recombination | Phages | Virulence | Data processing | Evolutionary genetics | Genetic diversity | Drug resistance | leukocidin | Soft tissues | Toxic shock syndrome | Infection | Pulsed-field gel electrophoresis | Abscesses | Sepsis | genomics | Genotypes
Journal Article
Infection, Genetics and Evolution, ISSN 1567-1348, 09/2019, Volume 73, pp. 255 - 260
is a major human pathogen causing infections with high morbidity and mortality in both healthcare and community settings. The accessory gene regulator (Agr) is... 
Pediatrics | Staphylococcus aureus | Agr functionality | Wound infections | SYSTEM | INFECTIOUS DISEASES | TOXIN | AGR GROUP | RESISTANCE | PREVALENCE | EXPRESSION | Medical colleges | Staphylococcal infections | Mortality | Genes | Antibacterial agents | Analysis | Genetic research | Genetic aspects | Virulence (Microbiology) | Bacterial genetics | Health aspects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e18617 - e18617
Staphylococcus aureus is a leading cause of bloodstream infections worldwide. In the United States, many of these infections are caused by a strain known as... 
GAMMA-HEMOLYSIN | VIRULENCE DETERMINANT | PHAGOCYTOSIS | PANTON-VALENTINE LEUKOCIDIN | MULTIDISCIPLINARY SCIENCES | STREAM INFECTIONS | IRON | SIDEROPHORE | USA300 | MODEL | IDENTIFICATION | Neutrophils - cytology | Hemolysin Proteins - genetics | Humans | Cell Membrane Permeability | Gene Expression Profiling | RNA, Messenger - metabolism | Exotoxins - metabolism | Virulence - genetics | Gene Deletion | Serum - microbiology | Bacterial Toxins - genetics | Staphylococcal Infections - microbiology | Neutrophils - microbiology | Disease Models, Animal | Staphylococcus aureus - genetics | Staphylococcal Infections - genetics | RNA, Messenger - genetics | Bacterial Proteins - genetics | Microbial Viability | Staphylococcus aureus - pathogenicity | Bacterial Toxins - metabolism | Animals | Exotoxins - genetics | Bacterial Proteins - metabolism | Mice | Porosity | Gene Expression Regulation, Bacterial | Hemolysin Proteins - metabolism | Infection | Analysis | Staphylococcal infections | Genes | Genetic aspects | Bacterial genetics | Gene expression | Health aspects | Staphylococcus aureus | Soybeans | Media (culture) | Laboratories | Genomics | Virulence | Infections | Blood | Metastases | Clonal deletion | Deletion | Bacteria | Strains (organisms) | Culture | Growth conditions | Immunization | Laboratory culture | Cell survival | Redundancy | Staphylococcus infections | Leukocytes (neutrophilic) | Survival | Bacteremia | Abscesses | Lysis | Culture media | Skin | Toxins | Phagocytosis | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 06/2010, Volume 6, Issue 6, pp. e1000944 - e1000944
Staphylococcus aureus frequently invades the human bloodstream, leading to life threatening bacteremia and often secondary foci of infection. Failure of... 
SMALL-COLONY VARIANTS | UNITED-STATES | LONG-TERM | ALARMONE (P)PPGPP | VANCOMYCIN RESISTANCE | MICROBIOLOGY | HEMB MUTANTS | METHICILLIN-RESISTANT | VIROLOGY | 23S RIBOSOMAL-RNA | ENDOTHELIAL-CELLS | MULTIDRUG-RESISTANCE | PARASITOLOGY | Linezolid | Oligonucleotide Array Sequence Analysis | Humans | Ligases - genetics | Methyltransferases - genetics | Molecular Sequence Data | Acetamides - pharmacology | Male | Gene Expression Profiling | Microbial Sensitivity Tests | Point Mutation - genetics | RNA, Ribosomal, 23S - genetics | Virulence - genetics | Staphylococcal Infections - microbiology | Drug Resistance, Bacterial - genetics | Biomarkers - metabolism | Staphylococcus aureus - genetics | Amino Acid Sequence | Staphylococcal Infections - drug therapy | Staphylococcal Infections - genetics | Staphylococcus aureus - isolation & purification | RNA, Messenger - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Sequence Homology, Amino Acid | Oxazolidinones - pharmacology | Aged | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Drug resistance in microorganisms | Genetic aspects | Research | Health aspects | Staphylococcus aureus | Microbial mutation | Index Medicus | Medical research | Microbiology | Mortality | Genes | Staphylococcus infections | Mutation | Bacteriology
Journal Article
Blood, ISSN 0006-4971, 03/2007, Volume 109, Issue 5, pp. 2066 - 2077
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2012, Volume 8, Issue 11, pp. e1003047 - e1003047
Neutrophil abscess formation is critical in innate immunity against many pathogens. Here, the mechanism of neutrophil abscess formation was investigated using... 
MYD88 DEFICIENCY | MICROBIOLOGY | NLRP3 INFLAMMASOME | IL-1 RECEPTOR | HYPER-IGE SYNDROME | GREEN FLUORESCENT PROTEIN | T(H)17 CELLS | VIROLOGY | PYOGENIC BACTERIAL-INFECTIONS | IN-VIVO | IL-17-PRODUCING T-CELLS | HOST-DEFENSE | PARASITOLOGY | Abscess - microbiology | Inflammasomes - metabolism | Toll-Like Receptor 2 - genetics | Abscess - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Staphylococcal Skin Infections - metabolism | Nod2 Signaling Adaptor Protein - genetics | Receptors, Formyl Peptide - immunology | Abscess - genetics | Adoptive Transfer | Interleukin-1beta - genetics | Mice, Mutant Strains | Staphylococcal Skin Infections - immunology | Receptors, Formyl Peptide - metabolism | Interleukin-1beta - biosynthesis | Neutrophils - metabolism | Carrier Proteins - immunology | Neutrophils - pathology | Neutrophils - immunology | Interleukin-1beta - immunology | Nod2 Signaling Adaptor Protein - immunology | Toll-Like Receptor 2 - metabolism | Staphylococcal Skin Infections - pathology | Inflammasomes - genetics | Carrier Proteins - genetics | Abscess - pathology | Animals | Carrier Proteins - metabolism | Nod2 Signaling Adaptor Protein - metabolism | Inflammasomes - immunology | Toll-Like Receptor 2 - immunology | Staphylococcus aureus - immunology | Mice | Abscess - immunology | Staphylococcal Skin Infections - microbiology | Receptors, Formyl Peptide - genetics | Staphylococcal Skin Infections - genetics | Index Medicus
Journal Article
Lancet Infectious Diseases, The, ISSN 1473-3099, 2011, Volume 11, Issue 8, pp. 595 - 603
Journal Article
Journal Article