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Science, ISSN 0036-8075, 8/2008, Volume 321, Issue 5889, pp. 691 - 696
MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to... 
Receptors | Phenotypes | Transfection | Cytokines | HEK293 cells | Genes | Cell lines | Fibroblasts | Agonists | Reports | Children | MYD88-DEFICIENT MICE | HERPES-SIMPLEX-VIRUS | PROTECTIVE IMMUNITY | MYELOID DIFFERENTIATION FACTOR-88 | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | HUMORAL IMMUNITY | STAPHYLOCOCCUS-AUREUS | AERUGINOSA LUNG INFECTION | HOST RESPONSE | CUTTING EDGE | Humans | Child, Preschool | Male | Mutation, Missense | Bacterial Infections - genetics | Pneumococcal Infections - immunology | Bacterial Infections - immunology | Gene Deletion | Pneumococcal Infections - genetics | Female | Toll-Like Receptors - metabolism | Child | Staphylococcal Infections - genetics | Disease Susceptibility | Cytokines - metabolism | Signal Transduction | Staphylococcal Infections - immunology | Receptors, Interleukin-1 - immunology | Toll-Like Receptors - immunology | Myeloid Differentiation Factor 88 - genetics | Immunity, Innate | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Receptors, Interleukin-1 - metabolism | Animals | Myeloid Differentiation Factor 88 - deficiency | Adolescent | Mice | Myeloid Differentiation Factor 88 - metabolism | Cell Line, Transformed | Genetic aspects | Bacterial infections | Pediatrics | Bacteria | Biomedical research | Genetic disorders | Immunology | Pneumococcal Infections | Life Sciences | Toll-Like Receptors | Bacterial Infections | Myeloid Differentiation Factor 88 | Bacteriology | Staphylococcal Infections | Microbiology and Parasitology | Pseudomonas Infections | Receptors, Interleukin-1
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 03/2016, Volume 193, Issue 5, pp. 504 - 515
Rationale: Cystic fibrosis (CF) is characterized by early structural lung disease caused by pulmonary infections. The nasopharynx of infants is a major... 
Healthy controls | Cystic fibrosis | Microbiota | Nasopharynx | Longitudinal | microbiota | SMALL-COLONY VARIANTS | CARRIAGE | HAEMOPHILUS-INFLUENZAE | COMMUNITIES | CHILDREN | STREPTOCOCCUS-PNEUMONIAE | INHIBITION | RESPIRATORY SYSTEM | cystic fibrosis | INFLAMMATION | LUNG-DISEASE | STAPHYLOCOCCUS-AUREUS | longitudinal | nasopharynx | healthy controls | CRITICAL CARE MEDICINE | Carrier State - epidemiology | Streptococcus mitis - genetics | Prospective Studies | Humans | Corynebacterium Infections - epidemiology | Carrier State - microbiology | Haemophilus Infections - epidemiology | Infant | Male | Corynebacterium Infections - microbiology | Case-Control Studies | Anti-Bacterial Agents - therapeutic use | Enterobacteriaceae Infections - epidemiology | Female | Staphylococcal Infections - microbiology | Nasopharynx - microbiology | Real-Time Polymerase Chain Reaction | Burkholderia Infections - microbiology | Haemophilus Infections - drug therapy | Infant, Newborn | Staphylococcus aureus - genetics | Moraxellaceae Infections - epidemiology | Streptococcal Infections - microbiology | Burkholderia - genetics | Staphylococcal Infections - drug therapy | Burkholderia Infections - epidemiology | Cystic Fibrosis - microbiology | Enterobacteriaceae Infections - microbiology | Enterobacteriaceae - genetics | Moraxellaceae Infections - microbiology | Streptococcal Infections - epidemiology | Haemophilus influenzae - genetics | Corynebacterium - genetics | Cystic Fibrosis - epidemiology | Moraxellaceae Infections - drug therapy | DNA, Bacterial - genetics | Staphylococcal Infections - epidemiology | Corynebacterium Infections - drug therapy | Microbiota - genetics | Burkholderia Infections - drug therapy | Haemophilus Infections - microbiology | RNA, Ribosomal, 16S - genetics | Streptococcal Infections - drug therapy | Moraxella - genetics | Cohort Studies | Enterobacteriaceae Infections - drug therapy
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 6/2008, Volume 46, Issue 5, pp. S344 - S349
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 7/2013, Volume 471, Issue 7, pp. 2383 - 2399
Staphylococcus aureus is the most common organism responsible for orthopaedic surgical site infections (SSIs). Patients who are carriers for... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Orthopedics | Surgery | Conservative Orthopedics | Medicine/Public Health, general | SURGERY | JOINT-REPLACEMENT SURGERY | COST-EFFECTIVENESS | HOSPITAL STAFF | ACTIVE SURVEILLANCE | INTENSIVE-CARE UNITS | SPINE SURGERY | ORTHOPEDICS | NASAL CARRIAGE | INTRANASAL MUPIROCIN | WOUND INFECTIONS | NOSOCOMIAL INFECTIONS | Community-Acquired Infections - diagnosis | Community-Acquired Infections - therapy | Community-Acquired Infections - transmission | Hospital Costs | Cross Infection - economics | Humans | Orthopedic Procedures - adverse effects | Infection Control - methods | Cost Savings | Cross Infection - transmission | Staphylococcal Infections - microbiology | Surgical Wound Infection - transmission | Cross Infection - prevention & control | Mass Screening - economics | Community-Acquired Infections - economics | Surgical Wound Infection - economics | Anti-Infective Agents - therapeutic use | Treatment Outcome | Staphylococcal Infections - therapy | Staphylococcal Infections - transmission | Surgical Wound Infection - prevention & control | Staphylococcal Infections - diagnosis | Staphylococcal Infections - economics | Cost-Benefit Analysis | Cross Infection - microbiology | Surgical Wound Infection - diagnosis | Cross Infection - diagnosis | Orthopedic Procedures - economics | Staphylococcal Infections - prevention & control | Methicillin-Resistant Staphylococcus aureus - isolation & purification | Program Evaluation | Surgical Wound Infection - microbiology | Community-Acquired Infections - microbiology | Infection Control - economics | Online health care information services | Orthopedic surgery | Health aspects | Analysis | Staphylococcal infections | Staphylococcus aureus | Survey
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 2014, Volume 210, Issue 9, pp. 1357 - 1366
Background. Limitations in treatment of biofilm-associated bacterial infections are often due to subpopulation of persistent bacteria (persisters) tolerant to... 
aminoglycoside | persister | catheter-related infections | biofilm | proton motive force | DIAGNOSIS | INFECTIOUS DISEASES | INFECTIONS | MANAGEMENT | TOLERANCE | SUSCEPTIBILITY | MICROBIOLOGY | IMMUNOLOGY | ANTIBIOTIC-LOCK THERAPY | GENTAMICIN | PSEUDOMONAS-AERUGINOSA | L-ARGININE | GROWTH | Escherichia coli Infections - prevention & control | Central Venous Catheters - microbiology | Escherichia coli - drug effects | Gentamicins - administration & dosage | Catheter-Related Infections - prevention & control | Pseudomonas Infections - prevention & control | Arginine - administration & dosage | Gentamicins - pharmacology | Drug Therapy, Combination | Biofilms - drug effects | Escherichia coli Infections - drug therapy | Staphylococcal Infections - drug therapy | Pseudomonas Infections - drug therapy | Rats | Central Venous Catheters - adverse effects | Pseudomonas aeruginosa - drug effects | Catheter-Related Infections - drug therapy | Drug Synergism | Animals | Arginine - pharmacology | Staphylococcal Infections - prevention & control | Anti-Bacterial Agents - pharmacology | In Vitro Techniques | Staphylococcus aureus - drug effects | Hydrogen-Ion Concentration | Aminoglycosides | Health aspects | Research | Index Medicus | Abridged Index Medicus | Biofilms/drug effects | Gentamicins/administration & dosage | Anti-Bacterial Agents/pharmacology | Staphylococcal Infections/drug therapy | Arginine/administration & dosage | Life Sciences | Escherichia coli Infections/drug therapy | Staphylococcus aureus/drug effects | Gentamicins/pharmacology | Catheter-Related Infections/prevention & control | Pseudomonas aeruginosa/drug effects | Staphylococcal Infections/prevention & control | Catheter-Related Infections/drug therapy | Central Venous Catheters/microbiology | Escherichia coli/drug effects | Bacteriology | Microbiology and Parasitology | Central Venous Catheters/adverse effects | Arginine/pharmacology | Pseudomonas Infections/prevention & control | Escherichia coli Infections/prevention & control | Pseudomonas Infections/drug therapy
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 09/2015, Volume 61, Issue suppl 2, pp. S69 - S78
Skin and soft-tissue infections (SSTIs) are an important cause of morbidity and mortality among hospitalized patients and a major therapeutic challenge for... 
telavancin | necrotizing infections | skin infections | cellulitis | soft-tissue infections | INFECTIOUS DISEASES | HOSPITALIZED-PATIENTS | RISK-FACTORS | NECROTIZING FASCIITIS | PRACTICE GUIDELINES | CARE-ASSOCIATED INFECTIONS | MICROBIOLOGY | IMMUNOLOGY | RESISTANT STAPHYLOCOCCUS-AUREUS | COMPLICATED SKIN | STREPTOCOCCAL INFECTIONS | INJECTION-DRUG USERS | SURGICAL SITE INFECTION | Skin Diseases, Bacterial - microbiology | Humans | Skin Diseases, Bacterial - drug therapy | Oxazolidinones - therapeutic use | Gram-Negative Bacterial Infections - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Skin Diseases, Bacterial - epidemiology | Gram-Positive Bacterial Infections - microbiology | Soft Tissue Infections - drug therapy | Staphylococcal Infections - microbiology | Daptomycin - therapeutic use | Staphylococcal Infections - drug therapy | Methicillin-Resistant Staphylococcus aureus - drug effects | Gram-Negative Bacterial Infections - drug therapy | Clinical Trials as Topic | Soft Tissue Infections - epidemiology | Gram-Positive Bacterial Infections - epidemiology | Daptomycin - pharmacology | Soft Tissue Infections - microbiology | Staphylococcal Infections - epidemiology | Oxazolidinones - pharmacology | Gram-Negative Bacterial Infections - epidemiology | Anti-Bacterial Agents - pharmacology | North America - epidemiology | Aminoglycosides - pharmacology | Gram-Positive Bacterial Infections - drug therapy | Aminoglycosides - therapeutic use
Journal Article
Veterinary Microbiology, ISSN 0378-1135, 02/2017, Volume 200, pp. 71 - 78
Although the problems associated with healthcare-associated infections (HAI) and the emergence of zoonotic and multidrug-resistant pathogens in companion... 
Companion animals | Healthcare-associated infection | Nosocomial | MRSP | MRSA | ESBL | Public health | Infection control | RISK-FACTORS | PUBLIC-HEALTH | ESCHERICHIA-COLI | MICROBIOLOGY | TO-DOG TRANSMISSION | ANTIMICROBIAL RESISTANCE | NOSOCOMIAL INFECTIONS | SALMONELLA-TYPHIMURIUM | STAPHYLOCOCCUS-AUREUS MRSA | VETERINARY SCIENCES | KLEBSIELLA-PNEUMONIAE | Dog Diseases - epidemiology | Escherichia coli Infections - prevention & control | Escherichia coli - drug effects | Humans | Dog Diseases - microbiology | Hospitals, Animal | Opportunistic Infections - prevention & control | Staphylococcal Infections - veterinary | Cat Diseases - prevention & control | Horse Diseases - epidemiology | Salmonella Infections, Animal - prevention & control | Drug Resistance, Multiple, Bacterial | Horse Diseases - prevention & control | Cat Diseases - epidemiology | Escherichia coli Infections - veterinary | Staphylococcal Infections - microbiology | Dog Diseases - prevention & control | Cats | Opportunistic Infections - epidemiology | Methicillin-Resistant Staphylococcus aureus - drug effects | Escherichia coli Infections - microbiology | Salmonella - drug effects | Staphylococcus - drug effects | Salmonella Infections, Animal - epidemiology | Opportunistic Infections - microbiology | Cat Diseases - microbiology | Escherichia coli Infections - epidemiology | Pets | Animals | Staphylococcal Infections - epidemiology | Cross Infection - veterinary | Dogs | Salmonella Infections, Animal - microbiology | Horses | Staphylococcal Infections - prevention & control | Anti-Bacterial Agents - pharmacology | Horse Diseases - microbiology | Drug resistance in microorganisms | Beta lactamases | Pathogenic microorganisms | Health aspects | Wildlife conservation | Staphylococcal infections | Escherichia coli
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2009, Volume 34, Issue 1, pp. S2 - S7
Abstract Skin and soft tissue infections (SSTIs) are common and range in severity from minor, self-limiting, superficial infections to life-threatening... 
Infectious Disease | Community-acquired infections | Hospital infections | Staphylococci | Skin and soft tissue infections | Meticillin-resistant Staphylococcus aureus | Risk factors | Aetiology | INFECTIOUS DISEASES | ANTIBIOTICS | MANAGEMENT | PASTEURELLA-MULTOCIDA | GUIDELINES | MICROBIOLOGY | RESISTANT STAPHYLOCOCCUS-AUREUS | WOUND INFECTIONS | COMMUNITY | PANTON-VALENTINE LEUKOCIDIN | SURVEILLANCE | PHARMACOLOGY & PHARMACY | TOXIC-SHOCK-SYNDROME | Streptococcal Infections - microbiology | Skin Diseases, Bacterial - microbiology | Community-Acquired Infections - epidemiology | Staphylococcal Skin Infections - epidemiology | Bacterial Infections - drug therapy | Humans | Streptococcal Infections - epidemiology | Soft Tissue Infections - epidemiology | Soft Tissue Infections - microbiology | Staphylococcal Infections - epidemiology | Skin Diseases, Bacterial - epidemiology | Streptococcus - isolation & purification | Cross Infection - microbiology | Bacterial Infections - epidemiology | Staphylococcal Infections - microbiology | Methicillin-Resistant Staphylococcus aureus - isolation & purification | Community-Acquired Infections - microbiology | Staphylococcal Skin Infections - microbiology | Bacterial Infections - microbiology | Cross Infection - epidemiology | Cross infection | Nosocomial infections | Microbiology | Health aspects | Epidemiology | Staphylococcus aureus infections
Journal Article
11. MRSA
Book
American Journal of Emergency Medicine, ISSN 0735-6757, 2016, Volume 35, Issue 4, pp. 579 - 583
Abstract Objective The aim of this study was to evaluate procalcitonin (PCT) diagnostic accuracy in discriminating gram-negative (GN) from gram-positive (GP)... 
Emergency | Positive blood culture | Procalcitonin | Bacterial species | Gram-positive bacteria | Sepsis | Gram-negative bacteria | Infection sites | DIAGNOSIS | MANAGEMENT | ANTIBIOTIC USE | GUIDELINES | MARKERS | CALCITONIN | EMERGENCY MEDICINE | SEPTIC SHOCK | SERUM PROCALCITONIN | RESPIRATORY-TRACT INFECTIONS | Enterococcus faecalis | Escherichia coli | Humans | Middle Aged | Escherichia coli Infections - blood | Male | Acinetobacter Infections - blood | Bacteremia - microbiology | Gram-Negative Bacterial Infections - microbiology | Endocarditis, Bacterial - blood | Staphylococcus haemolyticus | Burkholderia cepacia | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Bacteremia - blood | Endocarditis, Bacterial - microbiology | Female | Urinary Tract Infections - microbiology | Retrospective Studies | Staphylococcal Infections - microbiology | Klebsiella Infections - blood | Burkholderia Infections - microbiology | Staphylococcal Infections - blood | Staphylococcus aureus | Acinetobacter Infections - microbiology | Pneumonia, Bacterial - blood | Calcitonin - blood | Emergency Service, Hospital | Intensive Care Units | Pneumonia, Bacterial - microbiology | Escherichia coli Infections - microbiology | Biomarkers - blood | Klebsiella Infections - microbiology | Gram-Positive Bacterial Infections - blood | Enterococcus faecium | Staphylococcus hominis | Acinetobacter baumannii | Urinary Tract Infections - blood | Staphylococcus epidermidis | Catheter-Related Infections - blood | Catheter-Related Infections - microbiology | Gram-Negative Bacterial Infections - blood | Aged | Burkholderia Infections - blood | Klebsiella pneumoniae | Bacteria | Health aspects | Medical research | Medical examination | Microbiology | Emergency medicine | Analysis | Endocarditis | Medicine, Experimental | Urinary tract infections | Blood | Klebsiella | Multiple sclerosis | Intensive care | Pneumonia | Disease | Laboratories | Lung cancer | Infections | Arthritis | Family medical history | Urinary tract |