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1. Full Text STAT3 the oncogene – still eluding therapy?
by Wake, Matthew S and Watson, Christine J
The FEBS journal, ISSN 1742-464X, 07/2015, Volume 282, Issue 14, pp. 2600 - 2611
cancer therapeutics | inhibitors | cancer | tumourigenesis | signalling | STAT3 | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neoplasms - metabolism | Protein Structure, Tertiary | STAT3 Transcription Factor - physiology | Humans | Gene Expression Regulation, Neoplastic | Neoplasms - pathology | STAT3 Transcription Factor - antagonists & inhibitors | Molecular Targeted Therapy - methods | Oncogenes | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Neoplasms - drug therapy | Oncology | Transcription factors | Tumorigenesis | Cancer therapies | Apoptosis | Index Medicus
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2. Full Text Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression
by Chalmin, Fanny and Mignot, Grégoire and Bruchard, Mélanie and Chevriaux, Angélique and Végran, Frédérique and Hichami, Aziz and Ladoire, Sylvain and Derangère, Valentin and Vincent, Julie and Masson, David and Robson, Simon C and Eberl, Gerard and Pallandre, Jean René and Borg, Christophe and Ryffel, Bernhard and Apetoh, Lionel and Rébé, Cédric and Ghiringhelli, Francois
Immunity (Cambridge, Mass.), ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 362 - 373
Life Sciences & Biomedicine | Immunology | Science & Technology | 5'-Nucleotidase - genetics | RNA, Small Interfering - genetics | Antigens, CD - genetics | DNA-Binding Proteins - metabolism | Th17 Cells - drug effects | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Transcription Factors - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Promoter Regions, Genetic | DNA-Binding Proteins - immunology | Mice, Inbred C57BL | Gene Expression Regulation | Mice, Transgenic | Binding Sites - genetics | Mice, Knockout | Transcription Factors - metabolism | Transforming Growth Factor beta - pharmacology | Animals | Interleukin-6 - pharmacology | Apyrase - genetics | Th17 Cells - immunology | T-Lymphocytes - immunology | Mice | STAT3 Transcription Factor - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - immunology | Autoimmunity | DNA binding proteins | T cells | Transforming growth factors | Proteins | Transcription factors | Statistical analysis | Plasmids | Rodents | Cytotoxicity | Deoxyribonucleic acid--DNA | Immune system | Cancer | Adenosine | CD8 antigen | Helper cells | Stat3 protein | Interleukin 23 | Inflammation | Lymphocytes T | Transforming growth factor- beta | Adoptive transfer | Immunosuppressive agents | Promoters | CD4 antigen | Interleukin 6 | Interleukin 1 | CD73 antigen | Ectonucleotidase | Differentiation | Tumors | Index Medicus | 5'-Nucleotidase | T-Lymphocytes | Interleukin-6 | Life Sciences | Lymphocytes, Tumor-Infiltrating | Apyrase | RNA, Small Interfering | STAT3 Transcription Factor | Th17 Cells | Transcription Factors | Binding Sites | Transforming Growth Factor beta | Antigens, CD | DNA-Binding Proteins
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3. Full Text The role of STAT3 in leading the crosstalk between human cancers and the immune system
by Wang, Yu and Shen, Yicheng and Wang, Sinan and Shen, Qiang and Zhou, Xuan
Cancer letters, ISSN 0304-3835, 02/2018, Volume 415, pp. 117 - 128
Immunosuppression | Immunity | STAT3 | Treg | Cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | T-Lymphocyte Subsets - immunology | Dendritic Cells - immunology | Humans | Immunity - immunology | Gene Expression Regulation, Neoplastic - immunology | Macrophages - metabolism | Models, Immunological | Neoplasms - genetics | Immune System - metabolism | Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | Immune System - immunology | STAT3 Transcription Factor - immunology | Immunity - genetics | Dendritic Cells - metabolism | Macrophages - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Prevention | Medical colleges | Immune response | Genes | Immunotherapy | Development and progression | Gene expression | Index Medicus | immunosuppression | cancer | immunity
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4. STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (Review)
by Wang, Xiaochun and Crowe, Philip J and Goldstein, David and Yang, Jia-Lin
International journal of oncology, ISSN 1019-6439, 10/2012, Volume 41, Issue 4, pp. 1181 - 1191
Constitutive activation of STAT3 | STAT3 inhibition | STAT3 inhibitor clinical trials | Cancer therapy | STAT3-related microRNA | Life Sciences & Biomedicine | Oncology | Science & Technology | RNA, Small Interfering - genetics | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | RNA, Antisense - therapeutic use | Signal Transduction - genetics | Molecular Targeted Therapy | Neoplasms - therapy | Neoplasms - pathology | STAT3 Transcription Factor - antagonists & inhibitors | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - therapeutic use
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5. Full Text Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors
by Siveen, Kodappully Sivaraman and Sikka, Sakshi and Surana, Rohit and Dai, Xiaoyun and Zhang, Jingwen and Kumar, Alan Prem and Tan, Benny K.H and Sethi, Gautam and Bishayee, Anupam
Biochimica et biophysica acta. Reviews on cancer, ISSN 0304-419X, 04/2014, Volume 1845, Issue 2, pp. 136 - 154
Tumorigenesis | Inflammation | Inhibitors | Proliferation | Metastasis | STAT3 | Biochemistry & Molecular Biology | Oncology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Apoptosis - drug effects | Humans | Small Molecule Libraries - therapeutic use | Molecular Targeted Therapy | Carcinogenesis - drug effects | STAT3 Transcription Factor - biosynthesis | Neoplasm Metastasis | Neoplasms - genetics | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Neoplasm Invasiveness - genetics | Neoplasms - pathology | STAT3 Transcription Factor - antagonists & inhibitors | STAT3 Transcription Factor - genetics | Proteins | Development and progression | Lymphomas | Cancer
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