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Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 7, pp. 726 - 733
Altered gap junction coupling of cardiac myocytes during ischemia may contribute to development of lethal arrhythmias. The phosphoprotein connexin 43 (Cx43) is... 
Ischemia | Gap junctions | Glycolysis | Okadaic acid | Protein phosphatases | Connexin43 | Protein phosphorylation | AMP kinase | gap junctions | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | connexin43 | PHOSPHORYLATION | GAP JUNCTIONAL COMMUNICATION | glycolysis | CARDIAC MYOCYTES | ACTIN GENE | protein phosphorylation | okadaic acid | ischemia | IN-VITRO | INTERCELLULAR COMMUNICATION | PERIPHERAL VASCULAR DISEASE | JUN KINASE | protein phosphatases | RAT VENTRICULAR MYOCYTES | HEMATOLOGY | ADRENERGIC REGULATION | Okadaic Acid - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Recombinant Fusion Proteins - physiology | Myocardial Contraction - drug effects | Brefeldin A - pharmacology | Phenanthridines - pharmacology | Antimycin A - pharmacology | Aminoimidazole Carboxamide - pharmacology | Cell Hypoxia | Ribonucleotides - pharmacology | Alkaloids | Protein Processing, Post-Translational - drug effects | Adenosine Triphosphate - metabolism | Deoxyglucose - pharmacology | Tacrolimus - pharmacology | Indoles - pharmacology | Flavonoids - pharmacology | Potassium Cyanide - pharmacology | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Ouabain - pharmacology | Cells, Cultured - drug effects | Connexin 43 - metabolism | Rats | Imidazoles - pharmacology | Cycloheximide - pharmacology | Pyrroles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Benzophenanthridines | JNK Mitogen-Activated Protein Kinases - physiology | Myocytes, Cardiac - metabolism | Cells, Cultured - metabolism | Pyridines - pharmacology | Carbazoles - pharmacology | Staurosporine - pharmacology
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 05/2005, Volume 25, Issue 9, pp. 3553 - 3562
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
EARLY EMBRYONIC LETHALITY | DAMAGE CHECKPOINT | CELL-DIVISION | XENOPUS EGG EXTRACTS | ACTIVATION | COMPLEX | CYCLIN-E | BIOCHEMISTRY & MOLECULAR BIOLOGY | IONIZING-RADIATION | S-PHASE CHECKPOINT | CDC25A | CELL BIOLOGY | RNA, Small Interfering - genetics | Phosphorylation | Protein Kinases - genetics | DNA Replication - drug effects | Humans | Staurosporine - analogs & derivatives | DNA-Binding Proteins - metabolism | DNA Damage - physiology | Caffeine - pharmacology | Cell Cycle Proteins - genetics | Roscovitine | Replication Protein A | Protein Kinases - pharmacology | Chromosomal Proteins, Non-Histone - metabolism | Protein-Serine-Threonine Kinases - physiology | Purines - pharmacology | DNA, Single-Stranded - metabolism | RNA, Small Interfering - pharmacology | Cell Cycle Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA Replication - physiology | Protein Kinases - physiology | Protein-Serine-Threonine Kinases - drug effects | Checkpoint Kinase 2 | Checkpoint Kinase 1 | Protein Kinase Inhibitors - pharmacology | Histones - metabolism | Cell Cycle Proteins - physiology | Staurosporine - pharmacology | Index Medicus | Gene Expression | RNA; Small Interfering/genetics/pharmacology | Caffeine/pharmacology | Protein Kinases/genetics/pharmacology/physiology | Protein-Serine-Threonine Kinases/drug effects/physiology | Purines/pharmacology | Tumor Suppressor Protein p53/metabolism | DNA Replication/drug effects/physiology | DNA-Binding Proteins/metabolism | Histones/metabolism | Cell Cycle Proteins/genetics/metabolism/physiology | DNA; Single-Stranded/metabolism | Chromosomal Proteins; Non-Histone/metabolism | Protein Kinase Inhibitors/pharmacology | Staurosporine/analogs & derivatives/pharmacology | DNA Damage/physiology
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 14, pp. 2984 - 2992
Journal Article
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 06/1998, Volume 20, Issue 6, pp. 1211 - 1218
The mechanism through which kainate receptors downregulate the release of GABA in the hippocampus is not known. We have found that the action of kainate on the... 
PROTEIN-KINASE-C | GLUTAMATE RECEPTORS | INHIBITION | CA2+ CHANNELS | RAT HIPPOCAMPUS | SYNAPTIC TRANSMISSION | CURRENTS | HIPPOCAMPAL-NEURONS | EXPRESSION | NEUROSCIENCES | BRAIN | Tetraethylammonium - pharmacology | Rats, Wistar | Hippocampus - chemistry | gamma-Aminobutyric Acid - metabolism | Receptors, Metabotropic Glutamate - physiology | Type C Phospholipases - metabolism | Phorbol 12,13-Dibutyrate - pharmacology | Calcium - physiology | Carcinogens - pharmacology | Isoquinolines - pharmacology | Cyclic AMP - analogs & derivatives | Protein Kinase C - metabolism | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Hippocampus - enzymology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Tetrodotoxin - pharmacology | Virulence Factors, Bordetella | Membrane Potentials - drug effects | Sodium - pharmacology | Calcium - pharmacology | Kainic Acid - pharmacology | Enzyme Inhibitors - pharmacology | Pertussis Toxin | Phosphodiesterase Inhibitors - pharmacology | Rats | Excitatory Amino Acid Agonists - pharmacology | Thionucleotides - pharmacology | Enzyme Activation - drug effects | Cyclic AMP - pharmacology | Receptors, Kainic Acid - metabolism | Animals | Sulfonamides | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Second Messenger Systems - physiology | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism | Staurosporine - pharmacology | Phorbol esters | GABA | Protein kinases
Journal Article
American Journal of Pathology, ISSN 0002-9440, 07/2004, Volume 165, Issue 1, pp. 219 - 226
Journal Article
Blood, ISSN 0006-4971, 03/2011, Volume 117, Issue 12, pp. 3286 - 3293
We examined in vivo FLT3 inhibition in acute myeloid leukemia patients treated with chemotherapy followed by the FLT3 inhibitor lestaurtinib, comparing newly... 
AML | YOUNGER PATIENTS | INTENSIVE CHEMOTHERAPY | SERUM-LEVELS | TYROSINE KINASE INHIBITOR | ACUTE MYELOID-LEUKEMIA | MUTATIONS | HEMATOLOGY | CLINICAL-RESPONSE | APLASTIC-ANEMIA | STEM-CELL MOBILIZATION | Niacinamide - analogs & derivatives | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Humans | Staurosporine - analogs & derivatives | Antineoplastic Agents - therapeutic use | Benzenesulfonates - therapeutic use | Membrane Proteins - pharmacology | Phenylurea Compounds | Benzenesulfonates - pharmacology | Multicenter Studies as Topic | Protein Kinase Inhibitors - antagonists & inhibitors | Membrane Proteins - physiology | Inhibitory Concentration 50 | Leukemia, Myeloid, Acute - drug therapy | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Membrane Proteins - blood | Pyridines - therapeutic use | Antineoplastic Agents - antagonists & inhibitors | Leukemia, Myeloid, Acute - pathology | Cells, Cultured | Treatment Outcome | Leukemia, Myeloid, Acute - blood | Piperazines - therapeutic use | Piperazines - pharmacology | Randomized Controlled Trials as Topic | Indazoles - pharmacology | Drug Antagonism | Protein Kinase Inhibitors - therapeutic use | Staurosporine - therapeutic use | Carbazoles - therapeutic use | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Carbazoles - pharmacology | Indazoles - therapeutic use | Staurosporine - pharmacology | Clinical Trials and Observations
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 02/2012, Volume 11, Issue 2, pp. 427 - 438
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2000, Volume 97, Issue 3, pp. 1293 - 1298
Consistent with the epileptogenic and deleterious effects of the potent neurotoxin kainate, the activation of kainate receptors reduces the synaptic inhibition... 
Depolarization | Kainic acid receptors | Brain | Biological Sciences | Receptors | Neuroscience | Interneurons | Low concentrations | Neurons | Pyramidal cells | Agonists | ACTIVATION | INHIBITION | TEMPORAL-LOBE EPILEPSY | GLUTAMATE | DESENSITIZATION | MULTIDISCIPLINARY SCIENCES | KAINIC ACID | ANTAGONISM | CHANNELS | EXPRESSION | BRAIN | Amino acids | Research | Glutamate | Analysis | Cells | Neurotoxic agents
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 34, pp. 20841 - 20855
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 06/2004, Volume 18, Issue 9, pp. 1309 - 1309
Accumulation of inflammatory mononuclear phagocytes in Alzheimer's senile plaques, a hallmark of the innate immune response to beta-amyloid fibrils, can... 
ACTIVATION | G-protein coupled receptors | Alzheimer disease | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | immunosuppression | NEUTROPHILS | sphingosine-1-phosphate receptors | MESSENGER | PEPTIDE | CELL BIOLOGY | FIBRILS | MICROGLIA | SPHINGOSINE-1-PHOSPHATE | BIOLOGY | leukocytes | T-CELL CHEMOTAXIS | 1-PHOSPHATE | Phosphotransferases (Alcohol Group Acceptor) - physiology | Amyloid beta-Peptides - pharmacology | Humans | Maleimides - pharmacology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | RNA, Messenger - biosynthesis | Bombesin - pharmacology | Chemotaxis, Leukocyte - drug effects | Protein Processing, Post-Translational - drug effects | Vasoactive Intestinal Peptide - pharmacology | Neuropeptides - pharmacology | N-Formylmethionine Leucyl-Phenylalanine - pharmacology | Receptors, Lysosphingolipid - genetics | Indoles - pharmacology | Cholera Toxin - pharmacology | Heterotrimeric GTP-Binding Proteins - physiology | Phosphorylation - drug effects | Drug Evaluation, Preclinical | Pertussis Toxin - pharmacology | Propylene Glycols - pharmacology | Leukocytes, Mononuclear - drug effects | Calcitonin Gene-Related Peptide - pharmacology | Enzyme Inhibitors - pharmacology | Secretogranin II | Fingolimod Hydrochloride | Receptors, Lysosphingolipid - physiology | Tyrphostins - pharmacology | 1-Methyl-3-isobutylxanthine - pharmacology | Gene Expression Regulation - drug effects | Sphingosine - pharmacology | Cell Movement - drug effects | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Sphingosine - analogs & derivatives | Androstadienes - pharmacology | Receptors, Lysosphingolipid - agonists | Leukocytes, Mononuclear - cytology | Protein Kinase Inhibitors - pharmacology | Immunologic Factors - pharmacology | Receptors, Lysosphingolipid - biosynthesis | Staurosporine - pharmacology | Amyloid beta-Protein Precursor - pharmacology
Journal Article