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Clinical Cancer Research, ISSN 1078-0432, 05/2013, Volume 19, Issue 9, pp. 2368 - 2380
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 22, pp. 8882 - 8887
Journal Article
Oncogene, ISSN 0950-9232, 2017, Volume 36, Issue 32, pp. 4573 - 4584
Recent evidences suggest that stearoyl-CoA-desaturase 1 (SCD1), the enzyme involved in monounsaturated fatty acids synthesis, has a role in several cancers. We... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CENTER STAGE | YAP | FATTY-ACIDS | TAZ | CELL-DEATH | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | PATHWAY | THERAPEUTIC TARGET | GENETICS & HEREDITY | EXPRESSION | TUMORIGENESIS | Immunohistochemistry | Wnt3A Protein - metabolism | Adenocarcinoma - pathology | Prognosis | Adenocarcinoma of Lung | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Neoplasm Proteins - metabolism | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Adenocarcinoma - metabolism | Cell Nucleus - metabolism | Neoplastic Stem Cells - metabolism | HEK293 Cells | Female | Inhibitor of Apoptosis Proteins - metabolism | Protein Stability | Fatty Acids - metabolism | Protein-Serine-Threonine Kinases - metabolism | Down-Regulation | Stearoyl-CoA Desaturase - antagonists & inhibitors | Survivin | Stearoyl-CoA Desaturase - genetics | Axin Signaling Complex - metabolism | Stearoyl-CoA Desaturase - metabolism | Primary Cell Culture | Adaptor Proteins, Signal Transducing - metabolism | Adenocarcinoma - mortality | Care and treatment | Monounsaturated fatty acids | Research | Gene expression | Lung cancer | Stem cells | Adenocarcinoma | Cell survival | Transcription | Data processing | Desaturase | Fatty acids | Survival | Yes-associated protein | β-catenin | Localization | Bioinformatics | Index Medicus
Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 06/2010, Volume 9, Issue 6, pp. 1740 - 1754
Journal Article
Circulation, ISSN 0009-7322, 09/2008, Volume 118, Issue 14, pp. 1467 - 1475
Journal Article
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 04/2016, Volume 12, Issue 4, pp. 218 - 225
Journal Article
The FEBS Journal, ISSN 1742-464X, 02/2018, Volume 285, Issue 3, pp. 432 - 443
Metabolic activity of malignant cells is very different from that of their nontransformed equivalents, which establishes metabolic reprogramming as an... 
cancer | lysophosphatidic acid | metabolic reprogramming | lipid metabolism | TARGET | DE-NOVO LIPOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNTHESIS PATHWAY | STEAROYL-COA DESATURASE | INHIBITION | PROSTATE-CANCER | OVARIAN | FATTY-ACID SYNTHASE | EXPRESSION | Neoplasms - metabolism | Receptors, Lysophosphatidic Acid - metabolism | Lysophospholipids - metabolism | Drugs, Investigational - pharmacology | Humans | Drugs, Investigational - therapeutic use | Neoplasm Proteins - antagonists & inhibitors | Receptors, Lysophosphatidic Acid - genetics | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - agonists | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasms - blood | Lipids - blood | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Lysophosphatidic Acid - antagonists & inhibitors | Neoplasm Proteins - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | Lysophospholipids - antagonists & inhibitors | Phosphoric Diester Hydrolases - metabolism | Lipids - antagonists & inhibitors | Lysophospholipids - blood | Phosphoric Diester Hydrolases - genetics | Stearoyl-CoA Desaturase - antagonists & inhibitors | Fatty Acid Synthase, Type I - metabolism | Stearoyl-CoA Desaturase - genetics | Fatty Acid Synthase, Type I - antagonists & inhibitors | Neoplasms - drug therapy | Phosphoric Diester Hydrolases - chemistry | Animals | Neoplasm Proteins - agonists | Signal Transduction - drug effects | Sterol Regulatory Element Binding Protein 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Models, Biological | Lipogenesis - drug effects | Lipid Metabolism - drug effects | Stearoyl-CoA Desaturase - metabolism | Neoplasms - pathology | Physiological aspects | Cancer | Protein binding | Lipids | Biosynthesis | Metabolism | Signal transduction | Signaling | Lysophosphatidic acid | Rewiring | Transformed cells | Sterol regulatory element-binding protein | Stadiums | Lipid metabolism | Aberration
Journal Article
Cancer Letters, ISSN 0304-3835, 10/2017, Volume 406, pp. 93 - 104
Poor prognosis in lung cancer has been attributed to the presence of lung cancer stem cells (CSCs) which resist chemotherapy and cause disease recurrence.... 
MF-438 inhibitor | Lipid metabolism | Lung cancer stem cells | Fatty acids | Cisplatin | SURVIVAL | TARGET | PROGNOSIS | ADENOCARCINOMA | AUTOPHAGY | ONCOLOGY | EXPRESSION | CARCINOMA | REGISTRY | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Prognosis | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - pathology | Pyridazines - pharmacology | Case-Control Studies | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Drug Therapy, Combination | Thiadiazoles - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Squamous Cell - enzymology | Lung Neoplasms - enzymology | Endoplasmic Reticulum Stress - drug effects | Adenocarcinoma - enzymology | Survival Rate | Cisplatin - pharmacology | Stearoyl-CoA Desaturase - antagonists & inhibitors | Adenocarcinoma - drug therapy | Carcinoma, Squamous Cell - drug therapy | Cell Proliferation - drug effects | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Neoplasm Staging | Neoplastic Stem Cells - enzymology | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Relapse | Chemotherapy | Monounsaturated fatty acids | Lung cancer | Stem cells | Antineoplastic agents | Diseases | Cancer | Physiological aspects | Saturated fatty acids | Adenocarcinoma | Cell culture | Chemoresistance | Desaturase | Drug resistance | Cancer therapies | Autophagy | β-catenin | Immunotherapy | New combinations | Cell cycle | Inhibition | Enzymes | Cultures | Gene expression | Spheroids | Yes-associated protein | Studies | Biomarkers | Endoplasmic reticulum | Phagocytosis | Apoptosis | Index Medicus
Journal Article