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Cell Stem Cell, ISSN 1934-5909, 09/2012, Volume 11, Issue 3, pp. 401 - 414
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and... 
MAMMALIAN TARGET | CANCER PATIENTS | RAPAMYCIN | HEAD | AGING PHENOTYPES | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RESPONSE | TUMOR | NECK | SKIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Death - radiation effects | TOR Serine-Threonine Kinases - metabolism | Keratinocytes - radiation effects | Carcinoma, Squamous Cell - pathology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cell Compartmentation - radiation effects | Mucositis - prevention & control | Mouth Mucosa - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mouth Mucosa - radiation effects | Mucositis - pathology | Stem Cells - enzymology | Mucositis - enzymology | Cellular Senescence - radiation effects | Cytoprotection - drug effects | Clone Cells | Oxidative Stress - radiation effects | Cell Death - drug effects | Head and Neck Neoplasms - enzymology | Mouth Mucosa - pathology | Keratinocytes - enzymology | Superoxide Dismutase - metabolism | Radiation, Ionizing | Carcinoma, Squamous Cell - enzymology | Epithelial Cells - radiation effects | Cells, Cultured | Stem Cells - radiation effects | Epithelial Cells - pathology | Radiation Injuries - enzymology | Sirolimus - pharmacology | Head and Neck Neoplasms - pathology | Keratinocytes - pathology | Animals | Keratinocytes - drug effects | Radiation Injuries - prevention & control | Epithelial Cells - enzymology | Cell Compartmentation - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Radiation Injuries - pathology | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Cell Proliferation - radiation effects
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2014, Volume 32, Issue 34, pp. 3810 - 3816
Journal Article
STEM CELLS, ISSN 1066-5099, 02/2013, Volume 31, Issue 2, pp. 372 - 383
Hematopoietic stem and progenitor cells (HSPCs), which continuously maintain all mature blood cells, are regulated within the marrow microenvironment. We... 
Bone marrow | Irradiation | Prostaglandin E2 | Hematopoietic stem cells | Apoptosis | PROGENITOR CELLS | OSTEOBLASTIC MC3T3-E1 CELLS | WHOLE-BODY IRRADIATION | DUODENAL-ULCER | 16,16-DIMETHYL PROSTAGLANDIN-E2 | MACROPHAGES | BONE-MARROW | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CYCLOOXYGENASE-2 EXPRESSION | HEMATOLOGY | EXPOSURE | MEGAKARYOCYTE MATURATION | Whole-Body Irradiation | Gene Expression - drug effects | Apoptosis - drug effects | Apoptosis - radiation effects | Radiation Injuries, Experimental - immunology | Hematopoietic Stem Cells - pathology | Male | Actins - immunology | Actins - genetics | Cellular Microenvironment - radiation effects | Cyclooxygenase 2 - genetics | Radiation Injuries, Experimental - drug therapy | Radiation-Protective Agents - pharmacology | Bone Marrow Cells - drug effects | Macrophages - radiation effects | Cyclooxygenase 2 - immunology | Hematopoietic Stem Cells - radiation effects | Cell Differentiation - radiation effects | Hematopoietic Stem Cells - drug effects | Cell Survival - drug effects | Dinoprostone - pharmacology | Macrophages - pathology | Bone Marrow Cells - pathology | Mice, Transgenic | Bone Marrow Cells - radiation effects | Radiation Injuries, Experimental - pathology | Cell Survival - radiation effects | Gene Expression - radiation effects | Animals | Cell Differentiation - drug effects | Dinoprostone - analogs & derivatives | Macrophages - drug effects | Cell Proliferation - drug effects | Mice | Cellular Microenvironment - drug effects | Cell Proliferation - radiation effects | Medical colleges | Nuclear radiation | Analysis | Prostaglandins E | Information management | Macrophages
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1609 - 1614
Radiation therapy can result in bone injury with the development of fractures and often can lead to delayed and nonunion of bone. There is no prevention or... 
Femur | Free radicals | Stem cells | Irradiation | Bone marrow | Bones | Physical trauma | Bone marrow cells | Radiation damage | Mesenchymal stem cells | CFU-fibroblast | Self-renewal | Angiography | Repopulation | Differentiation | MIGRATION | CAPACITY | differentiation | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | OSTEOGENESIS | self-renewal | angiography | CHEMOTHERAPY | TRANSPLANTATION | ORIGIN | ENGRAFTMENT | THERAPY | repopulation | Femur - pathology | Leukocyte Common Antigens - metabolism | Mesenchymal Stromal Cells - radiation effects | Blood Vessels - pathology | Bone Marrow - radiation effects | Blood Vessels - radiation effects | Radiation Injuries, Experimental - etiology | Free Radicals - metabolism | Antigens, Ly - metabolism | Colony-Forming Units Assay | Membrane Proteins - metabolism | Radiation Injuries, Experimental - metabolism | Osteoblasts - radiation effects | Femur - metabolism | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Mesenchymal Stromal Cells - metabolism | Thiobarbituric Acid Reactive Substances - metabolism | Bone Marrow Cells - radiation effects | Radiation Injuries, Experimental - pathology | Fibroblasts - pathology | Femur - radiation effects | Integrin beta1 - metabolism | Osteoblasts - pathology | Animals | Fibroblasts - radiation effects | Bone Marrow - pathology | Mice | Mesenchymal Stromal Cells - pathology | Bone Marrow Cells - metabolism | Physiological aspects | Complications and side effects | Stem cell research | Care and treatment | Radiotherapy | Biological Sciences
Journal Article
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2017, Volume 19, Issue 8, pp. 891 - 903
Endothelial cells and leptin receptor(+) (LepR(+)) stromal cells are critical sources of haematopoietic stem cell (HSC) niche factors, including stem cell... 
PROGENITOR CELLS | MAINTENANCE | MESENCHYMAL STROMAL CELLS | SINUSOIDAL ENDOTHELIAL-CELLS | CRE | QUIESCENCE | NICHE | MAINTAIN | MICE | EXPRESSION | CELL BIOLOGY | Whole-Body Irradiation | Cell Proliferation | Receptors, Leptin - genetics | Humans | Adipocytes - drug effects | Time Factors | Hematopoiesis | Adiponectin - genetics | Bone Marrow Transplantation | Bone Marrow Cells - drug effects | Child | Hematopoietic Stem Cells - radiation effects | Hematopoietic Stem Cells - drug effects | Stem Cell Factor - metabolism | Stem Cell Niche | Paracrine Communication | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Genotype | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | Bone Marrow Cells - radiation effects | Cell Lineage | Regeneration | Phenotype | Animals | Adipocytes - metabolism | Adipocytes - radiation effects | Adolescent | Fluorouracil - pharmacology | Receptors, Leptin - metabolism | Bone Marrow Cells - metabolism | 5-Fluorouracil | Spine | Radiation | Stem cell transplantation | Vertebra | Adipocytes | Osteoblasts | Stem cell factor | Vascularization | Biomedical materials | Allografts | Clonal deletion | Bone marrow | Deletion | Bones | Biocompatibility | Inhibition | Vertebrae | Cell survival | Endothelial cells | Chemotherapy | Depletion | Stromal cells | Stem cells | Irradiation | Mice | Bone
Journal Article
Nature Neuroscience, ISSN 1097-6256, 06/2006, Volume 9, Issue 6, pp. 729 - 731
Environmental enrichment increases adult hippocampal neurogenesis and alters hippocampal-dependent behavior in rodents. To investigate a causal link between... 
NEURONS | MICE | LONG-TERM-MEMORY | DENTATE GYRUS | EXPRESSION | NEUROSCIENCES | Memory Disorders - physiopathology | Maze Learning - radiation effects | Neuronal Plasticity - drug effects | Bromodeoxyuridine | Anxiety - drug therapy | Behavior, Animal - radiation effects | Environment, Controlled | Habituation, Psychophysiologic - drug effects | Neuronal Plasticity - physiology | Dentate Gyrus - drug effects | Neurons - physiology | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Habituation, Psychophysiologic - radiation effects | Neurons - drug effects | Neuronal Plasticity - radiation effects | Maze Learning - physiology | Stem Cells - radiation effects | Anxiety - physiopathology | Cell Division - radiation effects | Behavior, Animal - physiology | Dentate Gyrus - radiation effects | Maze Learning - drug effects | Cell Division - drug effects | Feeding Behavior - physiology | Feeding Behavior - drug effects | Cell Division - physiology | Animals | Dentate Gyrus - physiology | Habituation, Psychophysiologic - physiology | X-Rays | Feeding Behavior - radiation effects | Stem Cells - drug effects | Stem Cells - physiology | Mice | Neurons - radiation effects | Cell Proliferation - radiation effects | Neural transmission | Regulation | Behavioral assessment | Research | Hippocampus (Brain) | Neurons
Journal Article