X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (415) 415
steroid 17-alpha-hydroxylase - antagonists & inhibitors (410) 410
male (386) 386
animals (303) 303
index medicus (279) 279
steroid 17-alpha-hydroxylase - metabolism (211) 211
prostatic neoplasms - drug therapy (143) 143
endocrinology & metabolism (140) 140
rats (139) 139
female (125) 125
enzyme inhibitors - pharmacology (119) 119
prostate cancer (115) 115
steroid 17-alpha-hydroxylase - genetics (110) 110
biochemistry & molecular biology (85) 85
oncology (84) 84
abiraterone acetate (79) 79
structure-activity relationship (74) 74
testis - enzymology (68) 68
chemistry, medicinal (66) 66
androgens (63) 63
cytochrome p-450 (63) 63
steroidogenesis (63) 63
testosterone (61) 61
enzyme inhibitors - chemistry (60) 60
microsomes - enzymology (60) 60
pharmacology & pharmacy (59) 59
abiraterone (58) 58
mice (58) 58
androgens - biosynthesis (56) 56
article (56) 56
cells, cultured (56) 56
androgen antagonists - therapeutic use (55) 55
cytochrome p-450 enzyme inhibitors (53) 53
prostatic neoplasms - pathology (53) 53
aged (52) 52
androstenes (52) 52
cyp17 (51) 51
expression (51) 51
kinetics (51) 51
middle aged (51) 51
prostatic neoplasms, castration-resistant - drug therapy (51) 51
androgen receptor (49) 49
cell line, tumor (49) 49
cancer (48) 48
rats, sprague-dawley (48) 48
enzyme inhibitors - chemical synthesis (47) 47
antineoplastic agents - therapeutic use (44) 44
receptors, androgen - metabolism (44) 44
aldehyde-lyases - antagonists & inhibitors (43) 43
enzyme inhibitors - therapeutic use (43) 43
ketoconazole (43) 43
enzymes (42) 42
testis - drug effects (42) 42
testosterone - blood (42) 42
imidazoles - pharmacology (41) 41
research (40) 40
androgens - metabolism (39) 39
antineoplastic agents - pharmacology (39) 39
androstenols - therapeutic use (38) 38
chemotherapy (38) 38
endocrine system (38) 38
physiological aspects (38) 38
aromatase - metabolism (37) 37
models, molecular (37) 37
prostatic neoplasms - enzymology (37) 37
testis - metabolism (37) 37
testosterone - biosynthesis (37) 37
treatment outcome (37) 37
antitumor-activity (36) 36
biosynthesis (36) 36
ketoconazole - pharmacology (36) 36
rna, messenger - metabolism (36) 36
steroid 17-alpha-hydroxylase (36) 36
urology & nephrology (36) 36
aromatase inhibitors (35) 35
orchiectomy (35) 35
progesterone - metabolism (35) 35
prostatic neoplasms - metabolism (35) 35
adult (34) 34
dose-response relationship, drug (34) 34
in-vitro (34) 34
prostate-cancer (34) 34
docetaxel (33) 33
androgen antagonists - pharmacology (32) 32
molecular structure (32) 32
steroids - biosynthesis (32) 32
aged, 80 and over (31) 31
drug design (31) 31
in vitro techniques (31) 31
androstadienes - therapeutic use (30) 30
cytochrome p-450 enzyme system - metabolism (30) 30
3-hydroxysteroid dehydrogenases - metabolism (29) 29
antineoplastic combined chemotherapy protocols - therapeutic use (29) 29
care and treatment (29) 29
gene-expression (29) 29
abridged index medicus (28) 28
imidazoles - chemistry (28) 28
androstenols - pharmacology (27) 27
gene expression (27) 27
increased survival (27) 27
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (575) 575
Japanese (11) 11
French (7) 7
German (3) 3
Russian (3) 3
Chinese (2) 2
Danish (1) 1
Italian (1) 1
Polish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 4, pp. 352 - 360
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 4, pp. 338 - 351
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2011, Volume 364, Issue 21, pp. 1995 - 2005
Journal Article
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7560, pp. 347 - 351
Prostate cancer resistance to castration occurs because tumours acquire the metabolic capability of converting precursor steroids to 5... 
ANDROGEN RECEPTOR | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | CYP17A1 INHIBITION | MECHANISM | TESTOSTERONE | RATIONALE | MULTIDISCIPLINARY SCIENCES | INCREASED SURVIVAL | CHEMOTHERAPY | EXPOSURE | ENZALUTAMIDE | Chromatin - metabolism | Prostatic Neoplasms - metabolism | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Androgen Receptor Antagonists - therapeutic use | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Androgens - biosynthesis | Male | Androstenes - pharmacology | Androgen Receptor Antagonists - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Biotransformation | Cell Division | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Prostatic Neoplasms - drug therapy | Dihydrotestosterone - metabolism | Phenylthiohydantoin - pharmacology | Prostatic Neoplasms - pathology | Androstenes - therapeutic use | 5-alpha Reductase Inhibitors - therapeutic use | Prostatic Neoplasms, Castration-Resistant - drug therapy | Phenylthiohydantoin - analogs & derivatives | Androgen Receptor Antagonists - metabolism | Xenograft Model Antitumor Assays | Androstenes - chemistry | Animals | Biosynthetic Pathways - drug effects | Survival Analysis | 5-alpha Reductase Inhibitors - pharmacology | Androstenes - metabolism | Prostatic Neoplasms - enzymology | Mice | Steroid 17-alpha-Hydroxylase - metabolism | 5-alpha Reductase Inhibitors - metabolism | Androgens - metabolism | Enzymes | Testosterone | Androgens | Metabolites | Ligands | Gene expression | Prostate cancer | Tumors
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 12, pp. 1210 - 1217
Journal Article