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Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2017, Volume 102, Issue 8, pp. 2701 - 2710
Context: Patients with 21-hydroxylase deficiency (21OHD) have long-term complications, resulting from poor disease control and/or glucocorticoid overtreatment.... 
ADRENOGENITAL SYNDROME | STIMULATION | FINAL HEIGHT | ADULT MALES | TISSUE | ENDOCRINOLOGY & METABOLISM | PATIENT | PREVALENCE | LONGITUDINAL ANALYSIS | 19-CARBON STEROIDS | HYPERPLASIA | Adrenal Glands - pathology | Hydroxytestosterones - metabolism | 17-alpha-Hydroxypregnenolone - analogs & derivatives | Adrenal Rest Tumor - metabolism | Humans | Middle Aged | Child, Preschool | Male | Hirsutism - metabolism | Testosterone - analogs & derivatives | Age Determination by Skeleton | Androstenedione - metabolism | Pregnenolone - metabolism | Young Adult | Androstenedione - analogs & derivatives | Menstruation Disturbances - metabolism | Testosterone - metabolism | Adult | Female | Child | 17-alpha-Hydroxypregnenolone - metabolism | Cross-Sectional Studies | Adrenal Hyperplasia, Congenital - metabolism | Testicular Neoplasms - metabolism | Organ Size | Cortodoxone - metabolism | Adolescent | Androstenes - metabolism | Aged | Androgens - metabolism | Drugs | Correlation | Glucocorticoids | Disorders | Bone tumors | Hormones | Males | Sulfates | Pregnenolone | Spectrometry | Children | Pituitary hormones | Menstruation | Complications | Hydroxylase | Hirsutism | Disease control | Patients | Testosterone | Androgens | Pregnenolone sulfate | Pituitary | Biomarkers | Adults | Sulfate | Females | Testes | Oxygenation | Steroid hormones | Tumors | Steroids
Journal Article
Hepatology, ISSN 0270-9139, 12/2012, Volume 56, Issue 6, pp. 2288 - 2296
Nuclear receptors (NRs) play crucial roles in the regulation of hepatic cholesterol synthesis, metabolism, and conversion to bile acids, but their actions in... 
NPC1L1 | PATHWAY | CELLULAR CHOLESTEROL | MACROPHAGES | GENE-EXPRESSION | ALPHA | MICE | ABSORPTION | SECRETION | GASTROENTEROLOGY & HEPATOLOGY | MODULATION | RNA-Binding Proteins - genetics | Steroid Hydroxylases - metabolism | Receptors, Estrogen - metabolism | Receptors, Steroid - metabolism | Bile Ducts - metabolism | Gene Expression Profiling | Hepatocytes - metabolism | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Calcitriol - genetics | Bile Ducts - cytology | Receptors, Thyroid Hormone - genetics | Liver X Receptors | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | ATP Binding Cassette Transporter 1 | Retinoid X Receptors - genetics | Retinoid X Receptors - metabolism | Steroid Hydroxylases - genetics | PPAR delta - genetics | PPAR gamma - genetics | Hepatocyte Nuclear Factor 4 - metabolism | Receptors, Estrogen - genetics | Cells, Cultured | Rats | Hepatocyte Nuclear Factor 4 - genetics | Receptors, Calcitriol - metabolism | Transcription Factors - genetics | Cholesterol - metabolism | Orphan Nuclear Receptors - genetics | Receptors, Thyroid Hormone - metabolism | Transcription Factors - metabolism | Animals | Receptors, Steroid - genetics | PPAR delta - metabolism | Homeostasis - genetics | RNA-Binding Proteins - metabolism
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 10/2013, Volume 379, Issue 1-2, pp. 62 - 73
Mitochondria are essential sites for steroid hormone biosynthesis. Mitochondria in the steroidogenic cells of the adrenal, gonad, placenta and brain contain... 
Cholesterol transport | Steroidogenesis | Steroidogenic acute regulatory protein | Cholesterol side chain cleavage | Vitamin D | Outer mitochondrial membrane | VITAMIN-D 1-ALPHA-HYDROXYLASE | CYTOCHROME P450(SCC) | CHAIN CLEAVAGE ENZYME | LIPOID ADRENAL-HYPERPLASIA | CHOLESTEROL-BINDING | ACUTE-REGULATORY-PROTEIN | LEYDIG TUMOR-CELLS | CELL BIOLOGY | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | ADRENODOXIN REDUCTASE | PERIPHERAL BENZODIAZEPINE-RECEPTOR | ENDOCRINOLOGY & METABOLISM | Mitochondria - enzymology | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Humans | Gonadal Steroid Hormones - biosynthesis | Voltage-Dependent Anion Channel 1 - metabolism | Mitochondria - metabolism | Cholesterol - metabolism | Phosphoproteins - metabolism | Mitochondrial Membranes - metabolism | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - metabolism | Adrenal Cortex Hormones - biosynthesis | Receptors, GABA - metabolism | Vitamin D - metabolism | Biological Transport - physiology | Membrane Proteins - metabolism | Mitochondrial Membranes - enzymology | Placental Hormones - biosynthesis | Adaptor Proteins, Signal Transducing - metabolism | Pregnenolone - biosynthesis | Enzymes | Physiological aspects | Calcifediol | Mitochondrial DNA | Alfacalcidol | Steroid hormones | Proteins | Regulators | Mitochondria | Hormones | Kinases | Cholesterol | Steroids
Journal Article
European Urology, ISSN 0302-2838, 2014, Volume 67, Issue 1, pp. 53 - 60
Abstract Background Enzalutamide is a novel antiandrogen with proven efficacy in metastatic castration-resistant prostate cancer (mCRPC). Objective To evaluate... 
Urology | Castration-resistant prostate cancer | Primary resistance to enzalutamide | Androgen signaling inhibition | Bone metastasis | Bone tumor microenvironment | Adaptive feedback mechanism | Androgen receptor | Predictors of outcome | Enzalutamide | Tissue-based research | TESTOSTERONE | CHEMOTHERAPY | RECEPTOR SPLICE VARIANTS | THERAPY | DEPRIVATION | CLINICAL-TRIALS | UROLOGY & NEPHROLOGY | INCREASED SURVIVAL | PROGRESSION | ABIRATERONE | Prospective Studies | Phenylthiohydantoin - therapeutic use | Humans | Middle Aged | Receptors, Androgen - metabolism | Retroviridae Proteins, Oncogenic - metabolism | Bone Neoplasms - secondary | Cytoplasm - metabolism | Drug Resistance, Neoplasm | Ki-67 Antigen - metabolism | Male | Antineoplastic Agents - therapeutic use | Receptors, Glucocorticoid - metabolism | Prostatic Neoplasms, Castration-Resistant - pathology | Bone Neoplasms - metabolism | Cell Nucleus - metabolism | Protein Isoforms - metabolism | Bone Marrow - metabolism | Aged, 80 and over | Adult | Bone Neoplasms - drug therapy | Testosterone - blood | Gene Dosage | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostatic Neoplasms, Castration-Resistant - metabolism | Bone Marrow Neoplasms - secondary | Phenylthiohydantoin - analogs & derivatives | Prostate-Specific Antigen - blood | Receptors, Androgen - genetics | Signal Transduction - drug effects | Bone Marrow Neoplasms - metabolism | Aged | Bone Marrow Neoplasms - drug therapy | Steroid 17-alpha-Hydroxylase - metabolism | Prostate cancer | Metastasis | Bone marrow biopsy | Androgen | Antiandrogens
Journal Article
Life Sciences, ISSN 0024-3205, 07/2011, Volume 89, Issue 1-2, pp. 57 - 64
Journal Article
1969, His Perspectives in cell biology, 176
Book
2009, ISBN 9780470086797, xxii, 330 p., [8] p. of plates
Providing an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development, this book equips drug development scientists... 
Drugs | Genetic regulation | Metabolism | Nuclear receptors (Biochemistry) | Chemistry | SCIENCE | Industrial & Technical
Book
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 2005, Volume 37, Issue 10, pp. 2047 - 2063
Skeletal muscle is a major mass peripheral tissue that accounts for ∼40% of the total body mass and a major player in energy balance. It accounts for >30% of... 
LIPID-METABOLISM | UNCOUPLING PROTEIN-3 GENE |