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The Journal of biological chemistry, ISSN 1083-351X, 02/2016, Volume 291, Issue 7, pp. 3254 - 3267
.... One way by which HCV promotes the accumulation of intracellular lipids is through enhancing de novo lipogenesis by activating the sterol regulatory element-binding proteins (SREBPs... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Hepatitis C, Chronic - pathology | Inflammasomes - metabolism | Cytoskeletal Proteins - antagonists & inhibitors | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Golgi Apparatus - drug effects | Humans | Hepatitis C, Chronic - virology | Non-alcoholic Fatty Liver Disease - etiology | Caspase 1 - metabolism | Host-Pathogen Interactions - drug effects | Intracellular Signaling Peptides and Proteins - metabolism | Protein Transport - drug effects | Sterol Regulatory Element Binding Protein 1 - agonists | RNA Interference | Hepacivirus - physiology | Sterol Regulatory Element Binding Protein 2 - metabolism | Endopeptidases - metabolism | Carrier Proteins - antagonists & inhibitors | Serine Endopeptidases - chemistry | Cysteine Proteinase Inhibitors - pharmacology | Cell Line, Tumor | Hepatocytes - virology | Sterol Regulatory Element Binding Protein 2 - agonists | Hepatitis C, Chronic - metabolism | Hepatitis C, Chronic - physiopathology | Hepatocytes - pathology | Golgi Apparatus - pathology | Hepatocytes - metabolism | Golgi Apparatus - virology | Caspase 1 - chemistry | Proteolysis - drug effects | Endopeptidases - chemistry | Inflammasomes - drug effects | Enzyme Induction - drug effects | Cytoskeletal Proteins - metabolism | Membrane Proteins - metabolism | Hepatocytes - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Hepacivirus - drug effects | Proprotein Convertases - metabolism | Proprotein Convertases - chemistry | Carrier Proteins - genetics | Carrier Proteins - metabolism | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Lipogenesis - drug effects | Golgi Apparatus - metabolism | Serine Endopeptidases - metabolism | Index Medicus | liver injury | SREBP | Microbiology | hepatitis virus | inflammation | inflammasome | lipid metabolism | NLRP3 inflammasome
Journal Article
Journal Article
The FEBS journal, ISSN 1742-464X, 02/2014, Volume 281, Issue 3, pp. 970 - 982
...‐binding cassette transporter A1, ATP‐binding cassette transporter G1, and sterol response element binding protein 1c... 
human leukocytes | liver X receptor α | extracellular signal‐related kinase (ERK)1/2 | inflammation | platelet‐activating factor | Extracellular signal-related kinase (ERK)1/2 | Liver X receptor α | Inflammation | Human leukocytes | Platelet-activating factor | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neutrophils - cytology | Oxidants - pharmacology | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Receptors, G-Protein-Coupled - metabolism | Humans | Platelet Activating Factor - antagonists & inhibitors | Orphan Nuclear Receptors - metabolism | Sterol Regulatory Element Binding Protein 1 - agonists | Platelet Membrane Glycoproteins - antagonists & inhibitors | ATP-Binding Cassette Transporters - genetics | Platelet Membrane Glycoproteins - metabolism | ATP Binding Cassette Transporter 1 - agonists | Phosphorylation - drug effects | Neutrophils - metabolism | Lymphocytes - metabolism | Neutrophils - drug effects | Orphan Nuclear Receptors - agonists | Lymphocytes - cytology | Orphan Nuclear Receptors - genetics | Platelet Activating Factor - metabolism | Macrophages - metabolism | Signal Transduction - drug effects | Receptors, G-Protein-Coupled - antagonists & inhibitors | Anticholesteremic Agents - antagonists & inhibitors | Oxidative Stress - drug effects | ATP Binding Cassette Transporter 1 - genetics | ATP-Binding Cassette Transporters - antagonists & inhibitors | Neutrophil Activation - drug effects | Receptors, G-Protein-Coupled - agonists | ATP Binding Cassette Transporter 1 - metabolism | ATP-Binding Cassette Transporters - agonists | Lymphocytes - immunology | Protein Isoforms - metabolism | Protein Processing, Post-Translational - drug effects | Liver X Receptors | ATP-Binding Cassette Transporters - metabolism | Platelet Membrane Glycoproteins - agonists | Macrophages - immunology | Sterol Regulatory Element Binding Protein 1 - metabolism | Cells, Cultured | Neutrophils - immunology | Platelet Activating Factor - agonists | Antioxidants - pharmacology | Macrophages - cytology | Down-Regulation - drug effects | Orphan Nuclear Receptors - antagonists & inhibitors | Protein Isoforms - biosynthesis | Sterol Regulatory Element Binding Protein 1 - genetics | Sterol Regulatory Element Binding Protein 1 - antagonists & inhibitors | ATP Binding Cassette Transporter 1 - antagonists & inhibitors | Anticholesteremic Agents - pharmacology | Protein Isoforms - genetics | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 03/2006, Volume 281, Issue 10, pp. 6211 - 6218
Journal Article
The FEBS journal, ISSN 1742-4658, 10/2017, Volume 285, Issue 3, pp. 432 - 443
.... In particular, the current arena of research in this field aims to understand the regulatory effect of oncogenic signaling on metabolic rewiring in transformed cells in order to exploit this for therapeutic benefit... 
cancer | lysophosphatidic acid | metabolic reprogramming | lipid metabolism | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neoplasms - metabolism | Receptors, Lysophosphatidic Acid - metabolism | Lysophospholipids - metabolism | Drugs, Investigational - pharmacology | Humans | Drugs, Investigational - therapeutic use | Neoplasm Proteins - antagonists & inhibitors | Receptors, Lysophosphatidic Acid - genetics | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - agonists | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasms - blood | Lipids - blood | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Lysophosphatidic Acid - antagonists & inhibitors | Neoplasm Proteins - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | Lysophospholipids - antagonists & inhibitors | Phosphoric Diester Hydrolases - metabolism | Lipids - antagonists & inhibitors | Lysophospholipids - blood | Phosphoric Diester Hydrolases - genetics | Stearoyl-CoA Desaturase - antagonists & inhibitors | Fatty Acid Synthase, Type I - metabolism | Stearoyl-CoA Desaturase - genetics | Fatty Acid Synthase, Type I - antagonists & inhibitors | Neoplasms - drug therapy | Phosphoric Diester Hydrolases - chemistry | Animals | Neoplasm Proteins - agonists | Signal Transduction - drug effects | Sterol Regulatory Element Binding Protein 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Models, Biological | Lipogenesis - drug effects | Lipid Metabolism - drug effects | Stearoyl-CoA Desaturase - metabolism | Neoplasms - pathology | Physiological aspects | Cancer | Protein binding | Lipids | Biosynthesis | Metabolism | Signal transduction | Signaling | Lysophosphatidic acid | Rewiring | Transformed cells | Sterol regulatory element-binding protein | Stadiums | Lipid metabolism | Aberration | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 03/2013, Volume 288, Issue 12, pp. 8505 - 8518
.... The steroidogenic acute regulatory protein (StAR) controls the rate-limiting step in steroid biosynthesis... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | RNA, Small Interfering - genetics | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Leydig Cells - enzymology | Cholesterol - blood | Sterol Esterase - metabolism | Male | Orphan Nuclear Receptors - metabolism | Phosphoproteins - metabolism | Cholesterol Esters - blood | Gene Knockdown Techniques | Cholesterol Side-Chain Cleavage Enzyme - genetics | Cyclic AMP - physiology | ATP-Binding Cassette Transporters - genetics | Leydig Cells - metabolism | Oxadiazoles - pharmacology | Liver X Receptors | ATP-Binding Cassette Transporters - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Progesterone - biosynthesis | ATP Binding Cassette Transporter 1 | Cyclic AMP - metabolism | Retinoid X Receptors - metabolism | Second Messenger Systems | Sterol Regulatory Element Binding Protein 1 - metabolism | Carbamates - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Promoter Regions, Genetic | Orphan Nuclear Receptors - agonists | Cells, Cultured | Gene Expression Regulation | Scavenger Receptors, Class B - genetics | Nicotinic Acids - pharmacology | Phosphoproteins - genetics | Orphan Nuclear Receptors - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Sterol Esterase - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Retinoid X Receptors - agonists | Tetrahydronaphthalenes - pharmacology | Sterol Esterase - physiology | Bucladesine - pharmacology | Mice | Scavenger Receptors, Class B - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Perilipin-1 | Index Medicus | Testis | Signal Transduction | Molecular Cell Biology | Cell Signaling | StAR Protein | Steroidogenesis | Steroidogenic Tissues | Cyclic AMP (cAMP)
Journal Article
Journal Article
Journal Article