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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 09/2010, Volume 107, Issue 40, pp. 17321 - 17326
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 03/2015, Volume 131, Issue 9, pp. 805 - 814
Journal Article
Journal Article
Human molecular genetics, ISSN 1460-2083, 10/2016, Volume 25, Issue 20, pp. 4556 - 4565
... (SREBF1, SREBF2, PHOSPHO1, SYNGAP1, ABCG1, CPT1A, MYLIP, TXNIP and SLC7A11) and 2 intergenic regions showed differential methylation in association with lipid traits... 
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Carnitine O-Palmitoyltransferase - genetics | Cholesterol - blood | Epigenesis, Genetic | Humans | Amino Acid Transport System y+ - genetics | Male | Genetic Loci | ATP Binding Cassette Transporter, Subfamily G, Member 1 - metabolism | Cardiovascular Diseases - enzymology | Cardiovascular Diseases - genetics | Cholesterol - chemistry | ras GTPase-Activating Proteins - genetics | DNA Methylation | Amino Acid Transport System y+ - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Carnitine O-Palmitoyltransferase - metabolism | Female | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Genetic Predisposition to Disease | Phosphoric Monoester Hydrolases - genetics | ras GTPase-Activating Proteins - metabolism | Cardiovascular Diseases - metabolism | Genetic Association Studies | Ubiquitin-Protein Ligases - metabolism | Cholesterol - metabolism | Sequence Analysis, DNA | Triglycerides - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - genetics | Triglycerides - blood | CpG Islands | Triglycerides - genetics | Phosphoric Monoester Hydrolases - metabolism | Ubiquitin-Protein Ligases - genetics | Index Medicus | Epigènesi | ADN
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 02/2016, Volume 291, Issue 7, pp. 3254 - 3267
.... One way by which HCV promotes the accumulation of intracellular lipids is through enhancing de novo lipogenesis by activating the sterol regulatory element-binding proteins (SREBPs... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Hepatitis C, Chronic - pathology | Inflammasomes - metabolism | Cytoskeletal Proteins - antagonists & inhibitors | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Golgi Apparatus - drug effects | Humans | Hepatitis C, Chronic - virology | Non-alcoholic Fatty Liver Disease - etiology | Caspase 1 - metabolism | Host-Pathogen Interactions - drug effects | Intracellular Signaling Peptides and Proteins - metabolism | Protein Transport - drug effects | Sterol Regulatory Element Binding Protein 1 - agonists | RNA Interference | Hepacivirus - physiology | Sterol Regulatory Element Binding Protein 2 - metabolism | Endopeptidases - metabolism | Carrier Proteins - antagonists & inhibitors | Serine Endopeptidases - chemistry | Cysteine Proteinase Inhibitors - pharmacology | Cell Line, Tumor | Hepatocytes - virology | Sterol Regulatory Element Binding Protein 2 - agonists | Hepatitis C, Chronic - metabolism | Hepatitis C, Chronic - physiopathology | Hepatocytes - pathology | Golgi Apparatus - pathology | Hepatocytes - metabolism | Golgi Apparatus - virology | Caspase 1 - chemistry | Proteolysis - drug effects | Endopeptidases - chemistry | Inflammasomes - drug effects | Enzyme Induction - drug effects | Cytoskeletal Proteins - metabolism | Membrane Proteins - metabolism | Hepatocytes - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Hepacivirus - drug effects | Proprotein Convertases - metabolism | Proprotein Convertases - chemistry | Carrier Proteins - genetics | Carrier Proteins - metabolism | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Lipogenesis - drug effects | Golgi Apparatus - metabolism | Serine Endopeptidases - metabolism | Index Medicus | liver injury | SREBP | Microbiology | hepatitis virus | inflammation | inflammasome | lipid metabolism | NLRP3 inflammasome
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 06/2016, Volume 291, Issue 23, pp. 12171 - 12183
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 05/2010, Volume 328, Issue 5985, pp. 1570 - 1573
...) located within the gene encoding sterol-regulatory element-binding factor–2 (SREBF-2), a transcriptional regulator of cholesterol synthesis, modulates the expression of genes involved in cellular cholesterol transport... 
MicroRNA | Hepatocytes | HDL lipoproteins | Liver | Genes | REPORTS | Homeostasis | Gene expression regulation | Macrophages | Cholesterols | Endothelial cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Membrane Glycoproteins - metabolism | Cholesterol, Dietary - administration & dosage | Lipoproteins - genetics | Lipoproteins, HDL - blood | Humans | Lipoproteins, HDL - metabolism | MicroRNAs - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Dietary Fats - administration & dosage | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | ATP Binding Cassette Transporter 1 | Cell Line | Introns | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Membrane Glycoproteins - genetics | Proteins - genetics | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Mice | MicroRNAs - genetics | Hypercholesterolemia - genetics | Macrophages, Peritoneal - metabolism | Hypercholesterolemia - metabolism | Physiological aspects | Control | Research | High density lipoproteins | Cholesterol metabolism | Lipoproteins | Cellular biology | Ribonucleic acid--RNA | Gene expression | Cholesterol | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, pp. e70987 - e70987
.... We recently demonstrated that a key transcription factor for lipogenesis, sterol regulatory element-binding protein-1 (SREBP-1... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fatty Acid Synthase, Type I - genetics | Neoplasm Transplantation | Prostatic Neoplasms - metabolism | Epithelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Male | MicroRNAs - metabolism | Prostate - metabolism | Prostate - pathology | Caspases - metabolism | Prostatic Neoplasms - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Lipogenesis - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Epithelial Cells - cytology | Sterol Regulatory Element Binding Protein 1 - metabolism | Prostatic Neoplasms - pathology | Signal Transduction | Caspases - genetics | Cells, Cultured | Tumor Burden | Fatty Acid Synthase, Type I - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Cell Line, Tumor | Mice | MicroRNAs - genetics | Hydroxymethylglutaryl CoA Reductases - genetics | MicroRNA | Synthesis | Genes | Cancer cells | B cells | Health aspects | Fatty acids | Protein binding | Apoptosis | Cell culture | Epithelial cells | Oncology | Biosynthesis | Biology | Metastasis | Cell growth | Restoration | Castration | Surgery | Xenografts | Sterol regulatory element-binding protein | miRNA | Inhibition | Lipid metabolism | Trends | Lipogenesis | Departments | Caspase | Tumorigenicity | Metabolism | Gene expression | Ribonucleic acid--RNA | Fatty-acid synthase | Cholesterol | Medicine | Androgens | MicroRNAs | Hydroxymethylglutaryl-CoA reductase | Aberration | Prostate cancer | Prostate | Cell migration | Cancer | Index Medicus | RNA | Ribonucleic acid
Journal Article