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Nature immunology, ISSN 1529-2908, 05/2013, Volume 14, Issue 5, pp. 489 - 499
Life Sciences & Biomedicine | Immunology | Science & Technology | RNA, Small Interfering - genetics | Cell Proliferation | Mice, Inbred C57BL | Transgenes - genetics | Cells, Cultured | Signal Transduction - genetics | Adaptive Immunity - genetics | Cell Differentiation - genetics | Signal Transduction - immunology | Lymphocyte Activation - genetics | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Mice, Mutant Strains | CD8-Positive T-Lymphocytes - metabolism | Mice | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | CD8-Positive T-Lymphocytes - immunology | Sterol Regulatory Element Binding Protein 1 - metabolism | Physiological aspects | Genetic aspects | Immune response | Research | Binding proteins | T cells | Index Medicus | lipids | metabolism | SREBP | LCMV | proliferation | CD8+ T cell
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 17, pp. 6623 - 6634
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | Multiprotein Complexes - genetics | Neoplasm Proteins - metabolism | Multiprotein Complexes - metabolism | MCF-7 Cells | Carcinoma, Hepatocellular - genetics | HEK293 Cells | Membrane Proteins - metabolism | Lipogenesis | Neoplasm Proteins - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | A549 Cells | Liver Neoplasms - genetics | Membrane Proteins - genetics | Thyroid Hormones - genetics | Hep G2 Cells | Carrier Proteins - genetics | Carrier Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - genetics | Thyroid Hormones - metabolism | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Carcinoma, Hepatocellular - metabolism | Index Medicus | Editors' Picks | gene transcription | lipid synthesis | cell proliferation | PKM2 | lipid metabolism | pyruvate kinase | lipogenesis | liver cancer | sterol regulatory element–binding protein | hepatocellular carcinoma | SREBP-1a
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2010, Volume 328, Issue 5985, pp. 1566 - 1569
MicroRNA | Genes | HDL lipoproteins | REPORTS | Cell lines | Stem cells | Journalism | Gene expression regulation | Mice | Macrophages | Cholesterols | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Up-Regulation | Humans | Homeostasis | MicroRNAs - metabolism | Sterol Regulatory Element Binding Proteins - genetics | ATP-Binding Cassette Transporters - genetics | RNA Interference | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | 3' Untranslated Regions | ATP Binding Cassette Transporter 1 | Sterol Regulatory Element Binding Protein 1 - metabolism | Cell Line | Oligonucleotides, Antisense - pharmacology | Introns | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Sterol Regulatory Element Binding Proteins - metabolism | Cholesterol - metabolism | Macrophages - metabolism | Animals | Diet | Sterol Regulatory Element Binding Protein 1 - genetics | Cholesterol, HDL - blood | MicroRNAs - genetics | Physiological aspects | Genetic aspects | Binding proteins | Cholesterol | Biosynthesis | Cellular biology | Ribonucleic acid--RNA | Gene expression | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 07/2010, Volume 39, Issue 2, pp. 171 - 183
CELLBIO | SIGNALING | Signaling | Cellbio | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Lipids - genetics | Cell Proliferation | Humans | Multiprotein Complexes | Protein Biosynthesis - physiology | Lipids - biosynthesis | Obesity - genetics | Mechanistic Target of Rapamycin Complex 1 | Proteins | Glycolysis - physiology | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Genomics - methods | Sterol Regulatory Element Binding Protein 1 - metabolism | Pentose Phosphate Pathway - physiology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Gene Expression Regulation - physiology | Transcription Factors - genetics | Metabolomics - methods | Obesity - metabolism | Transcription Factors - metabolism | Transcription, Genetic - physiology | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Mice | TOR Serine-Threonine Kinases | Cell Line, Transformed | Phosphates | Metabolites | Oncology, Experimental | Protein biosynthesis | Research | DNA binding proteins | Sugars | Public health | Cancer | Monosaccharides | Index Medicus | Bioenergetics
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 03/2020, Volume 295, Issue 12, pp. 3918 - 3928
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Endoplasmic Reticulum - metabolism | Ubiquitin-Protein Ligases - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | Ubiquitination | RNA Interference | Protein Domains | Membrane Proteins - metabolism | Sterol Regulatory Element Binding Protein 2 - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Amino Acid Sequence | Cell Line | DNA-Binding Proteins - antagonists & inhibitors | Mutagenesis, Site-Directed | Membrane Proteins - genetics | Ubiquitin-Protein Ligases - metabolism | DNA-Binding Proteins - genetics | Membrane Proteins - chemistry | Intracellular Signaling Peptides and Proteins - chemistry | Protein Binding | Golgi Apparatus - metabolism | Cholesterol - biosynthesis | Ubiquitin-Protein Ligases - genetics | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Cell metabolism, ISSN 1550-4131, 04/2011, Volume 13, Issue 4, pp. 376 - 388
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptors, LDL - genetics | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Atherosclerosis - drug therapy | Benzopyrans - therapeutic use | Metformin - therapeutic use | Humans | Insulin Resistance | Sterol Regulatory Element Binding Protein 2 - antagonists & inhibitors | Receptors, LDL - metabolism | Male | Fatty Liver - drug therapy | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Dietary Fats - pharmacology | Sterol Regulatory Element Binding Protein 1 - antagonists & inhibitors | Transcription, Genetic | Mice | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Lipogenesis | Sterol Regulatory Element Binding Protein 1 - metabolism | Disease Models, Animal | Type 2 diabetes | Liver diseases | Low density lipoproteins | Alcoholism | Oncology, Experimental | Research | Glucose | Gene expression | Dextrose | Atherosclerosis | Polyphenols | Insulin resistance | Binding proteins | Cancer | Protein binding | Medical colleges | Insulin | Cells | Index Medicus | Life Sciences
Journal Article
Cell metabolism, ISSN 1550-4131, 2011, Volume 13, Issue 5, pp. 540 - 549
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Salmonella Infections - immunology | Caspase 1 - metabolism | Male | Salmonella Infections - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Apoptosis Regulatory Proteins - genetics | Bone Marrow | Macrophages - immunology | Interleukin-1beta - secretion | Salmonella Infections - pathology | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Inflammasomes | Salmonella typhimurium - immunology | Mice, Inbred C57BL | RNA, Messenger - genetics | Lipid Metabolism | Macrophages - cytology | Sterol Regulatory Element Binding Protein 1 - physiology | Enzyme Activation - drug effects | Immunity, Innate | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Synthesis | Molecular genetics | Genes | Physiological aspects | Septic shock | Chemical properties | Genetic transcription | Macrophages | Mitogens | Fatty acids | Protein binding | Steroids | Index Medicus | Nlrp1 | SREBP-1a deficiency | Nalp1 | Inflammasome | lipogenesis | Macrophage
Journal Article
Biochemical journal, ISSN 0264-6021, 01/2010, Volume 425, Issue 1, pp. 215 - 223
Adipocyte | CCAAT/enhancer-binding protein(C/EBP) | Sterol-regulatory-element-binding protein 1c(SREBP1c) | Transcription | Lipid | Adipogenesis | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Humans | Adipocytes - cytology | DNA-Binding Proteins - metabolism | Chromatin Immunoprecipitation | RNA Interference | CCAAT-Enhancer-Binding Protein-delta - metabolism | CCAAT-Enhancer-Binding Proteins - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Promoter Regions, Genetic | CCAAT-Enhancer-Binding Protein-beta - genetics | Cells, Cultured | Gene Expression Regulation | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | 3T3-L1 Cells | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | CCAAT-Enhancer-Binding Protein-beta - metabolism | RUNX1 Translocation Partner 1 Protein | Transcription Factors - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | CCAAT-Enhancer-Binding Protein-delta - genetics | Adipocytes - metabolism | CCAAT-Enhancer-Binding Protein-alpha - genetics | Protein Binding | Mice | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 02/2016, Volume 35, Issue 5, pp. 642 - 650
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | F-Box-WD Repeat-Containing Protein 7 | TOR Serine-Threonine Kinases - metabolism | Humans | Maleimides - pharmacology | Mechanistic Target of Rapamycin Complex 2 | Gene Knockdown Techniques | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Transfection | Cell Cycle Proteins - genetics | Indoles - pharmacology | Lipogenesis | Sterol Regulatory Element Binding Protein 1 - metabolism | F-Box Proteins - metabolism | HCT116 Cells | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | Ubiquitin-Protein Ligases - metabolism | Glycogen Synthase Kinase 3 - metabolism | Neoplasms - drug therapy | Cell Line, Tumor | Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Enzymes | Cancer cells | Regulation | Genetic aspects | Gene expression | Binding proteins | Health aspects | Transcription factors | Cellular signal transduction | Carcinogenesis | Signal transduction | Protein expression | Cellular biology | Cancer | Index Medicus | degradation | SREBP1 | mTORC2 | GSK3 | FBXW7 | mTOR kinase inhibitors
Journal Article