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British Journal of Cancer, ISSN 0007-0920, 02/2018, Volume 118, Issue 3, pp. 428 - 434
Background: Periodontal pathogens have been linked to oral and gastrointestinal (orodigestive) carcinogenesis. However, the exact mechanisms remain unknown.... 
chymotrypsin-like proteinase | Treponema denticola | periodontopathogen | COLLAGENASE-2 MMP-8 | PORPHYROMONAS-GINGIVALIS | PANCREATIC-CANCER | TISSUE INHIBITORS | PERIODONTAL-DISEASE | METALLOPROTEINASES | ONCOLOGY | gastrointestinal cancer | ALPHA-1-ANTITRYPSIN | EXPRESSION | oral cancer | HUMAN NEUTROPHIL | PROGRESSION | Digestive System Neoplasms - metabolism | Pancreatic Neoplasms - chemistry | Adenocarcinoma - pathology | Pancreatic Neoplasms - metabolism | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Treponema denticola - enzymology | Mouth Neoplasms - metabolism | Stomach Neoplasms - pathology | Tonsillar Neoplasms - chemistry | Complement C1q - metabolism | Colonic Neoplasms - metabolism | Head and Neck Neoplasms - metabolism | Esophageal Neoplasms - pathology | Tonsillar Neoplasms - metabolism | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Head and Neck Neoplasms - chemistry | Matrix Metalloproteinase 9 - metabolism | Adenocarcinoma - metabolism | Matrix Metalloproteinase 8 - metabolism | Esophageal Neoplasms - metabolism | Digestive System Neoplasms - pathology | Colonic Neoplasms - chemistry | Stomach Neoplasms - chemistry | Adenocarcinoma - chemistry | Esophageal Neoplasms - chemistry | Tonsillar Neoplasms - pathology | Pancreatic Neoplasms - pathology | Carcinoma, Squamous Cell - chemistry | Mouth Neoplasms - chemistry | Head and Neck Neoplasms - pathology | Cell Transformation, Neoplastic - immunology | Digestive System Neoplasms - chemistry | alpha 1-Antichymotrypsin - metabolism | Colonic Neoplasms - pathology | Chymases - analysis | Mouth Neoplasms - pathology | Immunohistochemistry | Proteinase | Virulence | Tissue inhibitor of metalloproteinase 2 | Tissues | Tissue inhibitor of metalloproteinase 1 | Carcinogenesis | Proteins | Carcinogens | Pancreatic carcinoma | Bacteria | Colon | Pancreas | Gastric cancer | Squamous cell carcinoma | Tonsil | Immunomodulation | Teeth | Proteinase inhibitors | Esophagus | Complement component C1q | Chymotrypsin | Periodontitis | Neutrophil collagenase | Tumors | Index Medicus | Molecular Diagnostics
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2015, Volume 21, Issue 4, pp. 1329 - 1333
Mixed adenoneuroendocrine carcinoma(MANEC) is a rare tumor of the gastrointestinal tract that consists of a dual adenocarcinomatous and neuroendocrine... 
adenoneuroendocrine | Mixed | carcinoma;Composite | tumo | Carcinoembryonic antigen | Stomach | Composite tumor | Colorectal | Keratin 7 | Maspin | Mixed adenoneuroendocrine carcinoma | Cecum | Keratin 20 | Mixed tumor | COLORECTAL-CARCINOMA | NEUROENDOCRINE NEOPLASMS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | CD133 | Immunohistochemistry | Lymph Node Excision | Neoplasms, Complex and Mixed - genetics | Neoplasms, Complex and Mixed - secondary | Adenocarcinoma - pathology | Cecal Neoplasms - pathology | Humans | Middle Aged | Male | Stomach Neoplasms - pathology | Colectomy | Cecal Neoplasms - surgery | Female | Adenocarcinoma - genetics | Carcinoma, Neuroendocrine - chemistry | Cell Differentiation | Stomach Neoplasms - chemistry | Adenocarcinoma - chemistry | Stomach Neoplasms - genetics | Cecal Neoplasms - chemistry | Biomarkers, Tumor - analysis | Neoplasm Invasiveness | Cecal Neoplasms - genetics | Carcinoma, Neuroendocrine - genetics | Carcinoma, Neuroendocrine - surgery | Treatment Outcome | Carcinoma, Neuroendocrine - secondary | Lymphatic Metastasis | Gastrectomy | Adenocarcinoma - secondary | Neoplasms, Complex and Mixed - chemistry | Biopsy | Carcinoma, Neuroendocrine - pathology | Neoplasms, Complex and Mixed - surgery | Neoplasms, Complex and Mixed - pathology | Aged | Biomarkers, Tumor - genetics | Stomach Neoplasms - surgery | Adenocarcinoma - surgery | Index Medicus | Case Report
Journal Article
British Journal of Cancer, ISSN 0007-0920, 04/2011, Volume 104, Issue 9, pp. 1372 - 1376
BACKGROUND: Trastuzumab has recently shown efficacy in the treatment of HER2-positive advanced gastric adenocarcinoma. Although antibody-based therapies target... 
FISH | immunohistochemistry | gastric cancer | HER2 | PROGNOSTIC-FACTOR | ONCOLOGY | HER-2/NEU AMPLIFICATION | GENE AMPLIFICATION | HYBRIDIZATION | CANCER | ASSOCIATION | Index Medicus | Clinical Study
Journal Article
British Journal of Cancer, ISSN 0007-0920, 01/2009, Volume 100, Issue 2, pp. 298 - 304
This prospective study was conducted with the Korean Cancer Study Group to evaluate the efficacy and safety of cetuximab combined with modified FOLFOX6... 
Chemotherapy | Epidermal growth factor | Cetuximab | Gastric cancer | Epidermal growth factor receptor | Transforming growth factor-α | SURVIVAL | gastric cancer | PLUS IRINOTECAN | transforming growth factor-alpha | epidermal growth factor receptor | ADENOCARCINOMA | chemotherapy | METASTATIC COLORECTAL-CANCER | EGFR | KRAS MUTATIONS | GROWTH-FACTOR RECEPTOR | AMPHIREGULIN | ONCOLOGY | epidermal growth factor | GENE COPY NUMBER | EXPRESSION | Leucovorin - administration & dosage | Prognosis | Prospective Studies | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Stomach Neoplasms - pathology | Liver Neoplasms - chemistry | Peritoneal Neoplasms - chemistry | Antibodies, Monoclonal, Humanized | Organoplatinum Compounds - administration & dosage | Peritoneal Neoplasms - drug therapy | Fluorouracil - administration & dosage | Adult | Female | Stomach Neoplasms - chemistry | Liver Neoplasms - secondary | Peritoneal Neoplasms - secondary | Biomarkers, Tumor - analysis | Liver Neoplasms - drug therapy | Survival Rate | Treatment Outcome | Neoplasm Recurrence, Local - diagnosis | Stomach Neoplasms - drug therapy | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Neoplasm Staging | Index Medicus | transforming growth factor-α | Clinical Studies
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 11/2011, Volume 35, Issue 11, pp. 1712 - 1721
Journal Article
Clinica Chimica Acta, ISSN 0009-8981, 04/2015, Volume 444, pp. 132 - 136
Journal Article
Journal Article
Gut, ISSN 0017-5749, 05/2017, Volume 66, Issue 5, pp. 794 - 801
ObjectiveRecent data supports a significant role for immune checkpoint inhibitors in the treatment of solid tumours. Here, we evaluate gastric and... 
CARCINOMA PATIENTS | METASTASIS | MOLECULE | ANTIBODY | B7-H1 | PROGNOSTIC-SIGNIFICANCE | INDUCTION | GASTROENTEROLOGY & HEPATOLOGY | CANCER | PROGRAMMED DEATH-1 LIGAND-1 | LYMPHOCYTES | Adenocarcinoma - pathology | Humans | Middle Aged | DNA, Viral - analysis | Male | Stomach Neoplasms - pathology | Young Adult | Lymphocytes, Tumor-Infiltrating | Aged, 80 and over | Adult | Esophagogastric Junction - immunology | Female | Stomach Neoplasms - chemistry | Adenocarcinoma - chemistry | Esophagogastric Junction - virology | Stomach Neoplasms - virology | Neoplasm Invasiveness | Adenocarcinoma - immunology | Esophagogastric Junction - pathology | Survival Rate | B7-H1 Antigen - genetics | Adenocarcinoma - virology | Herpesvirus 4, Human | Stomach Neoplasms - immunology | Disease-Free Survival | Aged | B7-H1 Antigen - analysis | Esophagogastric Junction - chemistry | CD8-Positive T-Lymphocytes - immunology | Care and treatment | T cells | Stomach cancer | Immunity | Analysis | Immunohistochemistry | Cell survival | Dendritic cells | CD8 antigen | Stroma | Systematic review | Lymphocytes T | Hybridization | Patients | Cancer therapies | Esophagus | Cell adhesion & migration | Cell density | Metastases | Immune checkpoint | Lymphocytes | Medical prognosis | PD-L1 protein | Ligands | Solid tumors | Deoxyribonucleic acid--DNA | Tumors | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Asian Cardiovascular and Thoracic Annals, ISSN 0218-4923, 11/2017, Volume 25, Issue 9, pp. 645 - 648
We report the case of a 60-year-old man with 4 concurrent primary cancers: thyroid papillary carcinoma, esophageal squamous cell carcinoma, lung... 
Esophageal carcinoma | Gastrointestinal stromal tumors | Thyroid papillary carcinoma | multi-organ primary carcinoma | Non-small cell lung cancer | Neoplasms, Multiple Primary - surgery | Adenocarcinoma - pathology | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Thyroid Neoplasms - chemistry | Male | Tomography, X-Ray Computed | Esophageal Neoplasms - pathology | Esophageal Neoplasms - surgery | Goiter, Nodular - pathology | Stomach Neoplasms - chemistry | Adenocarcinoma - chemistry | Carcinoma, Papillary - chemistry | Esophageal Squamous Cell Carcinoma | Carcinoma, Papillary - diagnostic imaging | Esophageal Neoplasms - chemistry | Gastrointestinal Stromal Tumors - surgery | Stomach Neoplasms - diagnostic imaging | Lung Neoplasms - chemistry | Carcinoma, Squamous Cell - chemistry | Gastrectomy | Carcinoma, Papillary - surgery | Thyroidectomy | Thyroid Cancer, Papillary | Lung Neoplasms - diagnostic imaging | Lung Neoplasms - surgery | Adenocarcinoma - diagnostic imaging | Esophageal Neoplasms - diagnostic imaging | Adenocarcinoma - surgery | Lymph Node Excision | Adenocarcinoma of Lung | Thyroid Neoplasms - diagnostic imaging | Gastrointestinal Stromal Tumors - diagnostic imaging | Carcinoma, Squamous Cell - surgery | Lung Neoplasms - pathology | Stomach Neoplasms - pathology | Carcinoma, Squamous Cell - diagnostic imaging | Neoplasms, Multiple Primary - diagnostic imaging | Pneumonectomy | Gastrointestinal Stromal Tumors - pathology | Endoscopy, Digestive System | Goiter, Nodular - diagnostic imaging | Goiter, Nodular - surgery | Thyroid Neoplasms - surgery | Biomarkers, Tumor - analysis | Esophagectomy | Treatment Outcome | Neoplasms, Multiple Primary - pathology | Carcinoma, Papillary - pathology | Biopsy | Gastrointestinal Stromal Tumors - chemistry | Neoplasms, Multiple Primary - chemistry | Stomach Neoplasms - surgery | Thyroid Neoplasms - pathology | Index Medicus
Journal Article
Science, ISSN 0036-8075, 1/1998, Volume 279, Issue 5350, pp. 577 - 580
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the human digestive tract, but their molecular etiology and cellular origin... 
Complementary DNA | Lymphocytes | Cell lines | Reports | Mice | Mast cells | Genetic mutation | Small intestine | Summarization | Endothelial cells | Tumors | LIGAND-INDEPENDENT ACTIVATION | HUMAN SMALL-INTESTINE | W-LOCUS | POSSIBLE INVOLVEMENT | CONSTITUTIVE ACTIVATION | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | MAST-CELLS | SUBMUCOSAL BORDER | RECEPTOR TYROSINE KINASE | INTERSTITIAL-CELLS | Sequence Deletion | Antigens, CD34 - analysis | Phosphorylation | Gastrointestinal Neoplasms - genetics | Humans | Molecular Sequence Data | Stomach Neoplasms - metabolism | Stomach Neoplasms - pathology | Proto-Oncogene Proteins c-kit - metabolism | Esophageal Neoplasms - pathology | Phosphotyrosine - metabolism | Gastrointestinal Neoplasms - pathology | Transfection | Esophageal Neoplasms - metabolism | Stem Cell Factor - pharmacology | Proto-Oncogene Proteins c-kit - genetics | Intestinal Neoplasms - genetics | Stomach Neoplasms - genetics | Amino Acid Sequence | Cell Line | Recombinant Proteins - pharmacology | Proto-Oncogene Proteins c-kit - analysis | Intestinal Neoplasms - pathology | Gastrointestinal Neoplasms - chemistry | Animals | Esophageal Neoplasms - genetics | Cell Transformation, Neoplastic | Mice, Nude | Ligands | Mutation | Intestinal Neoplasms - chemistry | Proto-Oncogene Proteins c-kit - chemistry | DNA, Complementary | Digestive System - cytology | Mesentery | Research | Gastrointestinal tumors | Proteins | Digestive system | Deoxyribonucleic acid | DNA | Index Medicus
Journal Article