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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e49638 - e49638
Bacterial pathogens need to acquire nutrients from the host, but for many nutrients their importance during infection remain poorly understood. We have... 
UPTAKE ABC TRANSPORTER | IMMUNIZATION | POTD PROTECTS MICE | IRON UPTAKE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | ESCHERICHIA-COLI | GENES | SIGNATURE-TAGGED MUTAGENESIS | IDENTIFICATION | LIPOPROTEINS | Lipoproteins - deficiency | Sequence Deletion | Streptococcus pneumoniae - growth & development | Bacterial Vaccines - genetics | Lipoproteins - genetics | Virulence | Genetic Loci - genetics | ATP-Binding Cassette Transporters - deficiency | Streptococcus pneumoniae - pathogenicity | ATP-Binding Cassette Transporters - genetics | Biological Transport | Streptococcus pneumoniae - metabolism | Lipoproteins - metabolism | Streptococcus pneumoniae - genetics | ATP-Binding Cassette Transporters - metabolism | Bacterial Proteins - immunology | Bacterial Vaccines - metabolism | Methionine - metabolism | Bacterial Proteins - genetics | Methionine - biosynthesis | Phenotype | Sequence Alignment | Animals | Bacterial Vaccines - immunology | Bacterial Proteins - metabolism | Mice | ATP-Binding Cassette Transporters - immunology | Lipoproteins - immunology | Fluorescence spectroscopy | Physiological aspects | Medicine, Experimental | Medical research | Analysis | Salmonella | Animal models | Pneumonia | Mixed infection | Low concentrations | Laboratories | Pathogenesis | Immunoglobulin G | Vaccination | Disseminated infection | Fluorescence | Amino acids | Genomes | Infections | Biosynthesis | Vaccines | Polyamines | Medical schools | Streptococcus infections | Proteins | E coli | Bacteria | Nutrients | ABC transporters | Strains (organisms) | Spleen | Spectroscopy | Pathogens | Cloning | Methionine | Tryptophan | Titration calorimetry | Inflammation | Medicine | Studies | Streptococcus | Infectious diseases | Affinity | Calorimetry | Titration | Gene loci | Homocysteine | Transporter | ABC transporter | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 03/2012, Volume 8, Issue 3, pp. e1002574 - e1002574
The polysaccharide capsule of Streptococcus pneumoniae defines over ninety serotypes, which differ in their carriage prevalence and invasiveness for poorly... 
TYROSINE PHOSPHORYLATION | INVASIVE DISEASE | COLONIZATION PREVALENCE | GLYCOPROTEINS | SENSITIVE FLUORESCENCE DETECTION | MICROBIOLOGY | PERFORMANCE LIQUID-CHROMATOGRAPHY | IN-VITRO | VIROLOGY | INFECTION | SWITZERLAND | PARASITOLOGY | POLYSACCHARIDE | Streptococcus pneumoniae - classification | Streptococcus pneumoniae - ultrastructure | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Streptococcus pneumoniae - immunology | Phenotype | Pneumococcal Infections - immunology | Animals | Nasopharynx - immunology | Bacterial Capsules - genetics | Streptococcus pneumoniae - genetics | Female | Pneumococcal Infections - microbiology | Animals, Outbred Strains | Mice | Bacterial Capsules - ultrastructure | Mutation | Gene Expression Regulation, Bacterial | Nasopharynx - microbiology | Nasopharynx - pathology | Bacterial Capsules - immunology | Serotyping | Disease Models, Animal | Polysaccharides | Viral genetics | Physiological aspects | Genetic aspects | Research | Virulence (Microbiology) | Health aspects | Streptococcus pneumoniae | Genotype & phenotype | Statistical analysis | Disease | Ear diseases | Meningitis | Bacteria | Software | Experiments | Acquisitions & mergers | Streptococcus infections | Competition | Heart | Brain | Pneumonia | oligosaccharides | Infants | Nasopharynx | Vaccines | Energy | Children | Pathogens | Invasiveness | Operons | Electron microscopy | High-performance liquid chromatography | Metabolism | Bacteremia | Optical density | Infection | Polymerase chain reaction | Ear | Lag phase | Serotypes | Otitis media | Colonization | Index Medicus
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 2015, Volume 6, pp. 279 - 279
Journal Article
EMBO reports, ISSN 1469-221X, 09/2015, Volume 16, Issue 9, pp. 1203 - 1218
S treptococcus pneumoniae coinfection is a major cause of influenza‐associated mortality; however, the mechanisms underlying pathogenesis or protection remain... 
influenza | related apoptosis‐inducing ligand | treptococcus pneumoniae | 2 | CCR | S | TRAIL | C‐C‐chemokine receptor type | ) | neutrophil | TNF | TNF-related apoptosis-inducing ligand (TRAIL) | C-C-chemokine receptor type (CCR) 2 | Streptococcus pneumoniae | VIRUS-INFECTION | DENDRITIC CELLS | PANDEMIC INFLUENZA | BIOCHEMISTRY & MOLECULAR BIOLOGY | LETHAL SYNERGISM | NECROSIS-FACTOR-ALPHA | CELL BIOLOGY | BACTERIAL PNEUMONIA | NEGATIVE REGULATION | MOUSE MODEL | PNEUMOCOCCAL PNEUMONIA | TNF-ALPHA | Receptors, CCR2 - genetics | Lung - microbiology | Streptococcus pneumoniae - growth & development | Influenza A Virus, H3N2 Subtype | Humans | Orthomyxoviridae Infections - complications | Monocytes - immunology | Coinfection - physiopathology | Streptococcus pneumoniae - immunology | Lung - virology | Pneumococcal Infections - immunology | Streptococcus pneumoniae - pathogenicity | Tumor Necrosis Factor-alpha - immunology | Cytokines - immunology | Disease Models, Animal | Pneumococcal Infections - complications | Disease Susceptibility | Coinfection - immunology | Mice, Inbred C57BL | Neutrophils - immunology | Lung - physiopathology | TNF-Related Apoptosis-Inducing Ligand - metabolism | Animals | Mice | Receptors, CCR2 - deficiency | Lung - immunology | Orthomyxoviridae Infections - immunology | Ligands | Lungs | Influenza | Streptococcus infections | Apoptosis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0139238 - e0139238
Streptococcus pneumoniae persist in the human nasopharynx within organized biofilms. However, expansion to other tissues may cause severe infections such as... 
OTITIS-MEDIA | BACILLUS-SUBTILIS | CATABOLITE REPRESSION | EXTRACELLULAR DNA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DNA ADENINE METHYLATION | PNEUMOCOCCAL PNEUMONIA | EAR EPITHELIAL-CELLS | TRANSCRIPTIONAL REGULATION | BACTERIAL BIOFILMS | Biofilms - drug effects | Pneumococcal Infections - drug therapy | Virulence - drug effects | Cell Line | Plankton - drug effects | Small Molecule Libraries - pharmacology | Streptococcus pneumoniae - drug effects | Quorum Sensing - drug effects | Anti-Infective Agents - metabolism | Humans | Down-Regulation - drug effects | Up-Regulation - drug effects | Gene Expression Regulation, Bacterial - drug effects | DNA, Bacterial - genetics | Methyltransferases - antagonists & inhibitors | Epithelium - microbiology | Streptococcus pneumoniae - genetics | Drug resistance in microorganisms | DNA replication | Pneumonia | Dams | Growth | Genes | Transferases | Bacterial pneumonia | Gene expression | Streptococcus pneumoniae | Purines | Polysaccharides | DNA microarrays | Antibiotics | Analysis | Bacteria | Cellular signal transduction | Methylation | Health aspects | Elderly people | Target recognition | Pathogenesis | Genomics | Virulence | Ear diseases | Cytotoxicity | Drug resistance | Surgery | Quorum sensing | Inhibition | Laboratory apparatus | Deoxyribonucleic acid--DNA | Scanning electron microscopy | Enzymes | Macromolecules | Cell division | Protein biosynthesis | RNA polymerase | Metabolism | Electron microscopy | Epithelium | Fatty acids | Polymerase chain reaction | Biofilms | Inhibitors | DNA methyltransferase | Homeostasis | Otolaryngology | Confocal microscopy | Identification | Nasopharynx | Biosynthesis | Streptococcus infections | Metabolites | Cell cycle | DNA methylation | Clumps | Meningitis | Neck | Children | Therapeutic applications | Adenine | Staphylococcus infections | Bacteremia | Medicine | DNA biosynthesis | Cholecystokinin | Galactose | Elderly | Index Medicus | Deoxyribonucleic acid | DNA
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