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Crystal Structure of streptococcus pyogenes Sortase A: Implications for sortase mechanism
The Journal of biological chemistry, ISSN 0021-9258, 03/2009, Volume 284, Issue 11, pp. 6924 - 6933
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Aminoacyltransferases - antagonists & inhibitors | Cysteine Endopeptidases - chemistry | Protein Structure, Tertiary | Aminoacyltransferases - chemistry | Bacterial Proteins - antagonists & inhibitors | Oxidation-Reduction | Sulfenic Acids - chemistry | Streptococcus pyogenes - enzymology | Bacterial Proteins - chemistry | Crystallography, X-Ray | Kinetics | Catalytic Domain - physiology | Index Medicus | Enzyme Catalysis and Regulation
Journal Article
Molecular microbiology, ISSN 0950-382X, 12/2012, Volume 86, Issue 5, pp. 1052 - 1062
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Bacteriology | Amino Acid Sequence | Streptococcal Infections - microbiology | Catalytic Domain | Streptokinase - genetics | Plasminogen Activators | Humans | Virulence | Molecular Sequence Data | Mice, Transgenic | Plasminogen - metabolism | Sequence Analysis, DNA | Streptococcal Infections - mortality | Genetic Variation | Streptococcus pyogenes - genetics | Streptokinase - chemistry | Streptococcus pyogenes - pathogenicity | Animals | Plasminogen - chemistry | Streptococcus pyogenes - enzymology | Mice | Mutation | Streptokinase - metabolism | Analysis | Streptokinase | Bacteria | Molecular biology | Kinases | Pathogenesis | Plasmids | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 02/2010, Volume 285, Issue 8, pp. 5683 - 5694
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | NAD+ Nucleosidase - metabolism | Perforin - genetics | Saccharomyces cerevisiae - genetics | Humans | Adenosine Diphosphate Ribose - metabolism | Bacterial Proteins - chemistry | Protein Transport - physiology | Saccharomyces cerevisiae - metabolism | Streptococcus pyogenes - genetics | NAD+ Nucleosidase - genetics | Streptococcus pyogenes - pathogenicity | Niacinamide - chemistry | Adenosine Diphosphate Ribose - chemistry | Recombinant Proteins - metabolism | Niacinamide - metabolism | Perforin - chemistry | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | NAD+ Nucleosidase - chemistry | Streptococcus pyogenes - enzymology | Adenosine Diphosphate Ribose - genetics | Bacterial Proteins - metabolism | Niacinamide - genetics | Perforin - metabolism | Kinetics | Index Medicus | Drugs | Enzymes | Bacterial | Streptococcus | Bacteria | Organisms | Toxins | Catalysis | Enzymology | Xenobiotics
Journal Article
Nature (London), ISSN 0028-0836, 03/2015, Volume 519, Issue 7542, pp. 199 - 202
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Structure, Tertiary | CRISPR-Cas Systems - immunology | Streptococcus pyogenes - immunology | DNA, Viral - metabolism | Molecular Sequence Data | Substrate Specificity | Streptococcus pyogenes - virology | Streptococcus pyogenes - genetics | DNA, Viral - immunology | Nucleotide Motifs | Base Sequence | CRISPR-Associated Proteins - metabolism | Streptococcus pyogenes - enzymology | Protein Binding | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Clustered Regularly Interspaced Short Palindromic Repeats - immunology | DNA, Viral - genetics | Staphylococcus aureus | Virus diseases | Enzymes | RNA | Prokaryotes | Genetic aspects | Host-virus relationships | Health aspects | Bacteria | Genomes | Bacteriology | Viral infections | Deoxyribonucleic acid--DNA | Index Medicus | Virology | Life Sciences | Microbiology and Parasitology | CRISPR-Cas Systems | Clustered Regularly Interspaced Short Palindromic Repeats | Streptococcus pyogenes | Genetics | CRISPR-Associated Proteins | DNA, Viral
Journal Article
Proteins, structure, function, and bioinformatics, ISSN 0887-3585, 11/2020, Volume 88, Issue 11, pp. 1394 - 1400
STAPHYLOCOCCUS-AUREUS SORTASE | SURFACE-PROTEINS | To be checked for Publisher's Version | IDENTIFICATION | TRANSPEPTIDASE | protein engineering | SUBSTRATE-SPECIFICITY | SORTING SIGNAL | ENZYME | loop swapping | substrate specificity | computational analysis | Streptococcus pyogenessortase A | TOOL | Streptococcus pyogenes sortase A | Cysteine Endopeptidases - chemistry | Staphylococcus aureus - enzymology | Protein Engineering - methods | Aminoacyltransferases - genetics | Bacterial Proteins - chemistry | Substrate Specificity | Bacillus anthracis - enzymology | Cysteine Endopeptidases - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Oligopeptides - chemistry | Streptococcus pyogenes - chemistry | Bacillus anthracis - chemistry | Recombinant Proteins - metabolism | Aminoacyltransferases - chemistry | Protein Conformation, alpha-Helical | Gene Expression | Genetic Vectors - chemistry | Bacterial Proteins - genetics | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Oligopeptides - metabolism | Amino Acid Motifs | Staphylococcus aureus - chemistry | Sequence Homology, Amino Acid | Sequence Alignment | Protein Conformation, beta-Strand | Escherichia coli - genetics | Cysteine Endopeptidases - genetics | Streptococcus pyogenes - enzymology | Protein Binding | Aminoacyltransferases - metabolism | Bacterial Proteins - metabolism | Streptococcus | Enzymatic activity | Virulence factors | Substrate specificity | Virulence | Peptidoglycans | Substrates | Sortase | Mutants | Index Medicus
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 06/2015, Volume 461, Issue 3, pp. 487 - 493
Streptococcus pyogenes | Substrate inhibition | Succinic semialdehyde dehydrogenase | ESS-complex structure | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Succinate-Semialdehyde Dehydrogenase - chemistry | Streptococcus pyogenes - enzymology | Models, Molecular | Substrate Specificity | Crystallography, X-Ray | Protein Conformation | Succinate-Semialdehyde Dehydrogenase - metabolism | NADP - metabolism | Succinate-Semialdehyde Dehydrogenase - antagonists & inhibitors | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2013, Volume 57, Issue 6, pp. 2743 - 2750
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Infectious diseases | Bacterial diseases | Human bacterial diseases | Pharmacology. Drug treatments | Staphylococcal infections, streptococcal infections, pneumococcal infections | Biological and medical sciences | Medical sciences | Antibiotics. Antiinfectious agents. Antiparasitic agents | Streptococcus Phages - enzymology | Coinfection - drug therapy | Humans | Staphylococcal Infections - complications | Bacteremia - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Enzymes - genetics | Staphylococcal Infections - microbiology | Enzymes - therapeutic use | Disease Models, Animal | Streptococcal Infections - microbiology | Staphylococcal Infections - drug therapy | Streptococcus pyogenes - drug effects | Enzymes - administration & dosage | Methicillin-Resistant Staphylococcus aureus - drug effects | Bacteremia - drug therapy | Treatment Outcome | Streptococcus Phages - chemistry | Coinfection - microbiology | Animals | Enzymes - pharmacology | Streptococcal Infections - drug therapy | Anti-Bacterial Agents - pharmacology | Mice | Streptococcal Infections - complications | Anti-Bacterial Agents - administration & dosage | Index Medicus | Experimental Therapeutics
Journal Article
The Journal of infectious diseases, ISSN 0022-1899, 9/2005, Volume 192, Issue 5, pp. 783 - 790
Proteins | Interleukins | Cytokines | Neutrophils | Enzyme preparations | Streptococcus pyogenes | Bacteria | Mice | Infections | Chemokines | Western blotting | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Microbiology | Biological and medical sciences | Medical sciences | Bacteriology | Amino Acid Sequence | Neutrophils - cytology | Neutrophil Activation - immunology | Streptococcus pyogenes - immunology | Electrophoresis, Polyacrylamide Gel | Humans | Mice, Inbred C57BL | Streptococcus pyogenes - cytology | Neutrophils - immunology | Models, Molecular | Molecular Sequence Data | Fasciitis, Necrotizing - immunology | Interleukin-8 - antagonists & inhibitors | Cell Migration Inhibition | Animals | Streptococcus pyogenes - enzymology | Fasciitis, Necrotizing - microbiology | Female | Bacterial Proteins - immunology | Interleukin-8 - metabolism | Interleukin-8 - immunology | Peptide Hydrolases - metabolism | Prevention | Causes of | Dosage and administration | Drug therapy | Interleukin-8 | Index Medicus | Abridged Index Medicus
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 04/2018, Volume 26, Issue 7, pp. 1347 - 1355
Fc glycosylation | Transglycosylation | Chemoenzymatic synthesis | Glycoengineering | Endoglycosidase | Rituximab | Monoclonal antibody | Endo S | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Streptococcus pyogenes - enzymology | Bacterial Proteins - chemistry | Glycoside Hydrolases - chemistry | Polysaccharides - chemistry | Rituximab - metabolism | Bacterial Proteins - metabolism | Antibodies, Monoclonal - metabolism | Glycoside Hydrolases - metabolism | Rituximab - chemistry | Antibodies, Monoclonal - chemistry | Polysaccharides - metabolism | Hydrolysis | Enzymes | Biological products | Oxazoles | Immunoglobulin G | Monoclonal antibodies | Health aspects | Sugars | Monosaccharides | Index Medicus | rituximab
Journal Article
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 2014, Volume 58, Issue 4, pp. 2281 - 2288
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Microbial Sensitivity Tests | Streptococcus pyogenes - genetics | Streptococcus pneumoniae - drug effects | Trimethoprim Resistance - genetics | Streptococcus pyogenes - drug effects | Trimethoprim - pharmacology | Streptococcus pyogenes - enzymology | Streptococcus pneumoniae - genetics | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - genetics | Streptococcus pneumoniae - enzymology | Tetrahydrofolate Dehydrogenase - genetics | Index Medicus | Epidemiology and Surveillance
Journal Article
Nature biotechnology, ISSN 1087-0156, 04/2020, Volume 38, Issue 4, pp. 471 - 481
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Humans | Substrate Specificity | Directed Molecular Evolution | DNA - metabolism | CRISPR-Cas Systems - genetics | Gene Editing | Genome, Human - genetics | CRISPR-Associated Protein 9 - genetics | CRISPR-Associated Protein 9 - metabolism | DNA - genetics | Genetic Variation | Streptococcus pyogenes - genetics | Nucleotide Motifs | Streptococcus pyogenes - enzymology | HEK293 Cells | Mutation | DNA Cleavage | Streptococcus pyogenes | Usage | Nucleotide sequence | Analysis | Natural history | Genetic research | Sickle cell anemia | Scientific equipment and supplies industry | Cells | Anemia | Phages | Editing | Evolution | Sickle cell disease | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article