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1. Full Text crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
by Karvelis, Tautvydas and Gasiunas, Giedrius and Miksys, Algirdas and Barrangou, Rodolphe and Horvath, Philippe and Siksnys, Virginijus
RNA Biology, ISSN 1547-6286, 05/2013, Volume 10, Issue 5, pp. 841 - 851
The Cas9-crRNA complex of the Streptococcus thermophilus DGCC7710 CRISPR3-Cas system functions as an RNA-guided endonuclease with crRNA-directed target... 
CRISPR | Type II CRISPR-Cas systems | DNA silencing | CRISPR-CAS SYSTEMS | RNA CLEAVAGE | COMPLEX | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | ADAPTIVE IMMUNITY | ANTIVIRAL DEFENSE | ARCHAEA | BACTERIAL IMMUNE-SYSTEM | PROKARYOTES | CRISPR-Associated Proteins - chemistry | Ribonuclease III - genetics | Ribonuclease III - metabolism | CRISPR-Associated Proteins - genetics | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Molecular Sequence Data | Streptococcus pyogenes - metabolism | DNA - genetics | Streptococcus pyogenes - genetics | Sequence Alignment | Streptococcus thermophilus - metabolism | Escherichia coli - genetics | Base Sequence | CRISPR-Associated Proteins - metabolism | RNA, Bacterial - chemistry | Clustered Regularly Interspaced Short Palindromic Repeats | Escherichia coli - metabolism | RNA, Bacterial - genetics | Bacterial Proteins - metabolism | Ribonuclease III - chemistry | Streptococcus thermophilus - genetics | RNA, Bacterial - metabolism | Index Medicus | Research Paper
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2. Full Text Cas9 function and host genome sampling in type II-A CRISPR–cas adaptation
by Wei, Yunzhou and Terns, Rebecca M and Terns, Michael P
Genes and Development, ISSN 0890-9369, 2015, Volume 29, Issue 4, pp. 356 - 361
To acquire the ability to recognize and destroy virus and plasmid invaders, prokaryotic CRISPR-Cas systems capture fragments of DNA within the host CRISPR... 
CRISPR | Streptococcus thermophilus | Cas9 | PAM | Adaptation | COMPLEX | RNA | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | adaptation | TARGET DNA | CLASSIFICATION | DEVELOPMENTAL BIOLOGY | ADAPTIVE BACTERIAL IMMUNITY | CELL BIOLOGY | STREPTOCOCCUS-THERMOPHILUS | ENDONUCLEASE | GENETICS & HEREDITY | SYSTEMS | Genome, Bacterial - genetics | Streptococcus thermophilus - metabolism | CRISPR-Associated Proteins - metabolism | Streptococcus thermophilus - enzymology | Adaptation, Physiological - physiology | Streptococcus thermophilus - genetics | CRISPR-Cas Systems - genetics | Index Medicus | Research Communication
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3. Full Text The three major types of CRISPR‐Cas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus
by Carte, Jason and Christopher, Ross T and Smith, Justin T and Olson, Sara and Barrangou, Rodolphe and Moineau, Sylvain and Glover, Claiborne V. C and Graveley, Brenton R and Terns, Rebecca M and Terns, Michael P
Molecular Microbiology, ISSN 0950-382X, 07/2014, Volume 93, Issue 1, pp. 98 - 112
CRISPR ‐ Cas systems are small RNA ‐based immune systems that protect prokaryotes from invaders such as viruses and plasmids. We have investigated the features... 
COMPLEX | ANTIVIRAL DEFENSE | HUMAN GENOME | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | PROCESSES PRE-CRRNA | MICROBIOLOGY | INTERFERENCE | CLEAVAGE | ADAPTIVE BACTERIAL IMMUNITY | PROKARYOTES | Sequence Analysis, RNA | Streptococcus thermophilus - metabolism | CRISPR-Cas Systems | Bacterial Proteins - metabolism | Models, Genetic | Streptococcus thermophilus - genetics | RNA, Bacterial - metabolism | Proteins | RNA | Biosynthesis | Ribonucleic acid--RNA | Prokaryotes | Plasmids | Streptococcus infections | Index Medicus | Streptococcus thermophilus | Cas9 | Cas6 | CRISPR RNA biogenesis | tracrRNA
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4. Full Text A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems
by Kazlauskiene, Migle and Kostiuk, Georgij and Venclovas, Česlovas and Tamulaitis, Gintautas and Siksnys, Virginijus
Science, ISSN 0036-8075, 08/2017, Volume 357, Issue 6351, pp. 605 - 609
Type III CRISPR-Cas systems in prokaryotes provide immunity against invading nucleic acids through the coordinated degradation of transcriptionally active DNA... 
IMMUNITY | DNA CLEAVAGE | PROTEIN | RNA | RECOGNITION | CRYSTAL-STRUCTURE | ENDORIBONUCLEASE | MULTIDISCIPLINARY SCIENCES | EFFECTOR COMPLEX | SUPERFAMILY | DEGRADATION | Streptococcus Phages - physiology | Signal Transduction | Endonucleases - metabolism | RNA Stability | Streptococcus thermophilus - virology | Ribonucleases - metabolism | Streptococcus thermophilus - metabolism | Oligoribonucleotides - metabolism | Adenine Nucleotides - metabolism | CRISPR-Cas Systems | Protein Domains | Bacterial Proteins - metabolism | Streptococcus thermophilus - genetics | Ribonuclease A | CRISPR | Target recognition | Transcription | Prokaryotes | Phages | Genomes | Nucleic acids | Ribonucleic acid--RNA | Immunity | Degradation | Second messengers | Proteins | Signal transduction | Signaling | Synthesis | Palm | Nuclease | Deoxyribonucleic acid--DNA | Index Medicus
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5. Full Text Enhancing the sweetness of yoghurt through metabolic remodeling of carbohydrate metabolism in Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus
by Sørensen, Kim I and Curic-Bawden, Mirjana and Junge, Mette P and Janzen, Thomas and Johansen, Eric
Applied and Environmental Microbiology, ISSN 0099-2240, 06/2016, Volume 82, Issue 12, pp. 3683 - 3692
Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus are used in the fermentation of milk to produce yoghurt. These species normally... 
STRAINS | TRANSPORT | PROTEIN | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SEQUENCE | GENES | FERMENTATION | MICROBIOLOGY | LACTOCOCCUS-LACTIS | REVEALS | Metabolic Engineering | Industrial Microbiology | Galactose - metabolism | Humans | Carbohydrate Metabolism | Selection, Genetic | Yogurt - microbiology | Fermentation | Sequence Analysis, DNA | Yogurt - analysis | Metabolic Networks and Pathways - genetics | Lactose - metabolism | Streptococcus thermophilus - metabolism | DNA Mutational Analysis | Lactobacillus delbrueckii - genetics | Glucose - metabolism | Lactobacillus delbrueckii - metabolism | Streptococcus thermophilus - genetics | Mutation | Genetic aspects | Streptococcus | Research | Metabolism | Analysis | Lactobacillus | Probiotics | Glucose | Deoxyribonucleic acid--DNA | Streptococcus infections | Milk | Index Medicus
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6. Full Text Cleavage of phage DNA by the Streptococcus thermophilus CRISPR3-Cas system
by Magadán, Alfonso H and Dupuis, Marie-Ève and Villion, Manuela and Moineau, Sylvain
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e40913 - e40913
Streptococcus thermophilus, similar to other Bacteria and Archaea, has developed defense mechanisms to protect cells against invasion by foreign nucleic acids,... 
CRISPR/CAS SYSTEM | BACTERIOPHAGES | IMMUNE-SYSTEM | EVOLUTION | ARCHAEA | SEQUENCES | MULTIDISCIPLINARY SCIENCES | LACTIC-ACID BACTERIA | RESISTANCE | DIVERSITY | STRAIN | Amino Acid Sequence | Genome, Viral | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | DNA, Viral - metabolism | Molecular Sequence Data | Sequence Alignment | Streptococcus thermophilus - metabolism | Bacteriophages - metabolism | Base Sequence | Bacteriophages - genetics | Bacterial Proteins - metabolism | Streptococcus thermophilus - genetics | Catalysis | Mutation | Gene Order | Virus diseases | Infection | Genomics | DNA | Genomes | Bacterial genetics | Health aspects | CRISPR | Laboratories | Phages | Cloning | Archaea | Viruses | Amino acids | Yogurt | Biosynthesis | Genetic diversity | Infections | Nucleic acids | Gene expression | Loci | Proteins | Streptococcus | E coli | Bacteria | Cleavage | Genetic engineering | Deoxyribonucleic acid--DNA | Immune system | Index Medicus | Deoxyribonucleic acid
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7. Full Text Mixed-Culture Transcriptome Analysis Reveals the Molecular Basis of Mixed-Culture Growth in Streptococcus thermophilus and Lactobacillus bulgaricus
by Sander Sieuwerts and Douwe Molenaar and Sacha A. F. T. van Hijum and Marke Beerthuyzen and Marc J. A. Stevens and Patrick W. M. Janssen and Colin J. Ingham and Frank A. M. de Bok and Willem M. de Vos and Johan E. T. van Hylckama Vlieg
Applied and Environmental Microbiology, ISSN 0099-2240, 12/2010, Volume 76, Issue 23, pp. 7775 - 7784
Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
PATHWAYS | DELBRUECKII | METABOLISM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LACTIC-ACID BACTERIA | MICROBIOLOGY | PROTEINASES | YOGURT | IDENTIFICATION | PLANTARUM | MICROARRAY DATA | MILK | Lactobacillus - genetics | Lactobacillus - growth & development | Purines - metabolism | United States | Gene Expression Profiling | Yogurt - microbiology | Fermentation | Lactobacillus - metabolism | Streptococcus thermophilus - growth & development | Amino Acids - metabolism | Streptococcus thermophilus - metabolism | Streptococcus thermophilus - genetics | Fatty Acids - metabolism | Physiological aspects | Genetic aspects | Streptococcus | Fermented foods | Growth | Analysis | Vitamin B | Carbon dioxide | Bacteria | Yogurt | Physical growth | Bacteriology | Index Medicus | Food Microbiology
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8. Full Text Spatiotemporal Control of Type III-A CRISPR-Cas Immunity: Coupling DNA Degradation with the Target RNA Recognition
by Kazlauskiene, Migle and Tamulaitis, Gintautas and Kostiuk, Georgij and Venclovas, Česlovas and Siksnys, Virginijus
Molecular Cell, ISSN 1097-2765, 04/2016, Volume 62, Issue 2, pp. 295 - 306
(St) type III-A CRISPR-Cas system restricts MS2 RNA phage and cuts RNA in vitro. However, the CRISPR array spacers match DNA phages, raising the question: does... 
SYSTEM | DUAL-RNA | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | TRANSCRIPTION | GUIDED SURVEILLANCE COMPLEX | EFFECTOR COMPLEX | INTERFERENCE | CLEAVAGE | CMR COMPLEX | CELL BIOLOGY | RNA, Messenger - immunology | DNA, Bacterial - metabolism | Streptococcus thermophilus - immunology | DNA, Bacterial - immunology | RNA, Messenger - metabolism | Streptococcus thermophilus - virology | DNA, Single-Stranded - genetics | Escherichia coli - virology | RNA, Viral - genetics | Streptococcus thermophilus - metabolism | Time Factors | RNA-Directed DNA Polymerase - genetics | RNA, Viral - metabolism | Streptococcus thermophilus - genetics | Nucleic Acid Conformation | CRISPR-Associated Proteins - immunology | CRISPR-Cas Systems - immunology | RNA-Directed DNA Polymerase - metabolism | CRISPR-Associated Proteins - genetics | DNA, Single-Stranded - metabolism | RNA, Messenger - genetics | DNA, Viral - metabolism | Escherichia coli - immunology | Models, Molecular | RNA Cleavage | RNA Stability | Host-Pathogen Interactions | DNA, Single-Stranded - immunology | DNA, Viral - immunology | DNA, Bacterial - genetics | Escherichia coli - genetics | CRISPR-Associated Proteins - metabolism | Protein Conformation | RNA, Viral - immunology | Mutation | DNA, Viral - genetics | DNA | Messenger RNA | Ribonuclease | Index Medicus
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9. Short communication: Genomic and phenotypic analyses of exopolysaccharides produced by Streptococcus thermophilus KLDS SM
by Li, Bailiang and Ding, Xiuyun and Evivie, Smith Etareri and Jin, Da and Meng, Yueyue and Huo, Guicheng and Liu, Fei
Journal of Dairy Science, ISSN 0022-0302, 01/2018, Volume 101, Issue 1, pp. 106 - 112
Streptococcus thermophilus plays important roles in the dairy industry. Streptococcus thermophilus KLDS SM could produce a high amount of exopolysaccharides... 
monosaccharide composition | genome sequence | Streptococcus thermophilus | molecular mass | Polysaccharides, Bacterial - chemistry | Galactose - metabolism | Genomics | Bacterial Proteins - genetics | Streptococcus thermophilus - classification | Fermentation | Polysaccharides, Bacterial - biosynthesis | Phenotype | Animals | Streptococcus thermophilus - metabolism | Glucose - metabolism | Streptococcus thermophilus - isolation & purification | Bacterial Proteins - metabolism | Streptococcus thermophilus - genetics | France
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10. Full Text Genomic insights into high exopolysaccharide-producing dairy starter bacterium Streptococcus thermophilus ASCC 1275
by Wu, Qinglong and Tun, Hein Min and Leung, Frederick Chi-Ching and Shah, Nagendra P
Scientific Reports, ISSN 2045-2322, 05/2014, Volume 4, Issue 1, pp. 4974 - 4974
Streptococcus thermophilus ASCC 1275 (ST 1275), a typical dairy starter bacterium, yields the highest known amount (similar to 1,000 mg/L) of exopolysaccharide... 
SET YOGURT | PHYSICAL-CHARACTERISTICS | RHEOLOGICAL PROPERTIES | FUNCTIONALITY | MULTIDISCIPLINARY SCIENCES | LACTIC-ACID BACTERIA | LOW-FAT MOZZARELLA | TEXTURE CHARACTERISTICS | SEQUENCE | GENE CLUSTERS | CULTURES | Genome, Bacterial - genetics | Polysaccharides, Bacterial - genetics | Animals | Milk - microbiology | Streptococcus thermophilus - metabolism | Genes, Bacterial - genetics | Fermentation - physiology | Proteolysis | Stress, Physiological - genetics | Polysaccharides, Bacterial - metabolism | Streptococcus thermophilus - genetics | Dairy Products - microbiology | CRISPR | Excitatory postsynaptic potentials | Dairy products | Eps gene | Fermented food | Cheese | Yogurt | Genomes | Fermentation | Food | Milk | Index Medicus
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11. Full Text Characterization of the chemical structures and physical properties of exopolysaccharides produced by various Streptococcus thermophilus strains
by Pachekrepapol, U and Lucey, J.A and Gong, Y and Naran, R and Azadi, P
Journal of Dairy Science, ISSN 0022-0302, 05/2017, Volume 100, Issue 5, pp. 3424 - 3435
Exopolysaccharides (EPS) produced by some lactic acid bacteria are often used by the dairy industry to improve the rheological and physical properties of... 
exopolysaccharide | molar mass | Streptococcus thermophilus | acid milk gel | AGRICULTURE, DAIRY & ANIMAL SCIENCE | ACID | MOLECULAR-WEIGHTS | FOOD SCIENCE & TECHNOLOGY | RHEOLOGY | VISCOSITY | LASER-LIGHT SCATTERING | CHROMATOGRAPHY | TEXTURE | MASS | YOGURT | MILK | Animals | Gas Chromatography-Mass Spectrometry | Streptococcus thermophilus - metabolism | Polysaccharides, Bacterial - metabolism | Yogurt | Fermentation | Streptococcus - metabolism | Microbiological research | Polysaccharides | Streptococcus | Chemical properties | Research | Production processes | Physiological aspects | Structure | Index Medicus
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12. Full Text Proteolytic Activity and Production of γ-Aminobutyric Acid by Streptococcus thermophilus Cultivated in Microfiltered Pasteurized Milk
by Brasca, Milena and Hogenboom, Johannes A and Morandi, Stefano and Rosi, Veronica and D'Incecco, Paolo and Silvetti, Tiziana and Pellegrino, Luisa
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 11/2016, Volume 64, Issue 45, pp. 8604 - 8614
A set of 191 strains of Streptococcus thermophilus were preliminarily screened for the presence of the genes codifying for cell envelope-associated proteinase... 
ornithine | Streptococcus thermophilus | arginine | GABA | microfiltered milk | citrulline | free amino acids | proteolysis | BIOACTIVE PEPTIDES | SKIM MILK | FOOD SCIENCE & TECHNOLOGY | RAW-MILK | LACTOBACILLUS-BUCHNERI | BLOOD-PRESSURE | GRAM-POSITIVE BACTERIA | PEPTIDASE ACTIVITIES | AGRICULTURE, MULTIDISCIPLINARY | GLUTAMATE-DECARBOXYLASE | ENHANCED LEVELS | SALIVARIUS SUBSP THERMOPHILUS | CHEMISTRY, APPLIED | Milk - chemistry | Milk - microbiology | Lactoglobulins - metabolism | Bacterial Proteins - genetics | Caseins - metabolism | Pasteurization | Streptococcus thermophilus - enzymology | Streptococcus thermophilus - growth & development | Lactalbumin - metabolism | Hydrolysis | Amino Acids - metabolism | Animals | Streptococcus thermophilus - metabolism | gamma-Aminobutyric Acid - biosynthesis | Cattle | Bacterial Proteins - metabolism | Streptococcus thermophilus - genetics | Index Medicus
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13. Full Text Effects of long-term intake of a yogurt fermented with Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 on mice
by Usui, Yuki and Kimura, Yasumasa and Satoh, Takeshi and Takemura, Naoki and Ouchi, Yasuo and Ohmiya, Hiroko and Kobayashi, Kyosuke and Suzuki, Hiromi and Koyama, Satomi and Hagiwara, Satoko and Tanaka, Hirotoshi and Imoto, Seiya and Eberl, Gérard and Asami, Yukio and Fujimoto, Kosuke and Uematsu, Satoshi
International Immunology, ISSN 0953-8178, 06/2018, Volume 30, Issue 7, pp. 319 - 331
The gut is an extremely complicated ecosystem where micro-organisms, nutrients and host cells interact vigorously. Although the function of the intestine and... 
Aging | Metabolome | Probiotics | Intestinal epithelial barrier | Microbiome | METABOLITES | BARRIER FUNCTION | HOST | IMMUNOLOGY | microbiome | IMMUNE-SYSTEM | AGE-RELATED-CHANGES | GUT MICROBIOME | DISEASE | intestinal epithelial barrier | SENESCENCE | aging | HEALTH | IONIZATION MASS-SPECTROMETRY | metabolome | probiotics | Streptococcus thermophilus - immunology | Lactobacillus delbrueckii - immunology | Male | Yogurt - microbiology | Fermentation | Intestines - immunology | Mice, Inbred ICR | Animals | Intestines - microbiology | Streptococcus thermophilus - metabolism | Lactobacillus delbrueckii - genetics | Lactobacillus delbrueckii - metabolism | Mice | Streptococcus thermophilus - genetics | Probiotics - metabolism
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14. Full Text Variability of hydrolysis of β-, α s1-, and α s2-caseins by 10 strains of streptococcus thermophilus and resulting bioactive peptides
by Miclo, Laurent and Roux, Émeline and Genay, Magali and Brusseaux, Émilie and Poirson, Chantal and Jameh, Nawara and Perrin, Clarisse and Dary, Annie
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 01/2012, Volume 60, Issue 2, pp. 554 - 565
Milk proteins contain numerous potential bioactive peptides, which may be released by digestive proteases or by the proteolytic system of lactic acid bacteria... 
bioactive peptides | Streptococcus thermophilus | cell envelope proteinase | casein hydrolysis | Amino Acid Sequence | Caseins - metabolism | Molecular Sequence Data | Peptides - pharmacology | Hydrolysis | Animals | Peptides - metabolism | Streptococcus thermophilus - metabolism | Caseins - chemistry | Cattle | Bacterial Proteins - metabolism | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Serine Endopeptidases - metabolism | Peptides - analysis | Index Medicus
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15. Full Text Influence of different proteolytic strains of Streptococcus thermophilus in co-culture with Lactobacillus delbrueckii subsp. bulgaricus on the metabolite profile of set-yoghurt
by Settachaimongkon, Sarn and Nout, M.J. Robert and Antunes Fernandes, Elsa C and Hettinga, Kasper A and Vervoort, Jacques M and van Hooijdonk, Toon C.M and Zwietering, Marcel H and Smid, Eddy J and van Valenberg, Hein J.F
International Journal of Food Microbiology, ISSN 0168-1605, 05/2014, Volume 177, pp. 29 - 36
Proto-cooperation between and subsp. is one of the key factors that determine the fermentation process and final quality of yoghurt. In this study, the... 
Dairy | Starter culture | Metabolomics | Protease | Flavor | Fermented milk | Milk - chemistry | Multivariate Analysis | Streptococcus thermophilus - physiology | Gas Chromatography-Mass Spectrometry | Magnetic Resonance Spectroscopy | Volatile Organic Compounds - analysis | Lactobacillus delbrueckii - growth & development | Yogurt - microbiology | Fermentation | Food Microbiology | Streptococcus thermophilus - growth & development | Yogurt - analysis | Animals | Streptococcus thermophilus - metabolism | Lactobacillus delbrueckii - physiology | Lactobacillus delbrueckii - metabolism | Hydrogen-Ion Concentration | Yogurt - standards | Metabolites | Analysis | Index Medicus | functional foods | dairy-cows | shelf-life | lactic-acid bacteria | metabolomics | food fermentations | volatile compounds | flavor formation | fermented milks | nuclear-magnetic-resonance
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