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by Williams, Frances M K and Carter, Angela M and Hysi, Pirro G and Surdulescu, Gabriela and Hodgkiss, Dylan and Soranzo, Nicole and Traylor, Matthew and Bevan, Steve and Dichgans, Martin and Rothwell, Peter M W and Sudlow, Cathie and Farrall, Martin and Silander, Kaisa and Kaunisto, Mari and Wagner, Peter and Saarela, Olli and Kuulasmaa, Kari and Virtamo, Jarmo and Salomaa, Veikko and Amouyel, Philippe and Arveiler, Dominique and Ferrieres, Jean and Wiklund, Per-Gunnar and Ikram, M Arfan and Hofman, Albert and Boncoraglio, Giorgio B and Parati, Eugenio A and Helgadottir, Anna and Gretarsdottir, Solveig and Thorsteinsdottir, Unnur and Thorleifsson, Gudmar and Stefansson, Kari and Seshadri, Sudha and DeStefano, Anita and Gschwendtner, Andreas and Psaty, Bruce and Longstreth, Will and Mitchell, Braxton D and Cheng, Yu-Ching and Clarke, Robert and Ferrario, Marco and Bis, Joshua C and Levi, Christopher and Attia, John and Holliday, Elizabeth G and Scott, Rodney J and Fornage, Myriam and Sharma, Pankaj and Furie, Karen L and Rosand, Jonathan and Nalls, Mike and Meschia, James and Mosely, Thomas H and Evans, Alun and Palotie, Aarno and Markus, Hugh S and Grant, Peter J and Spector, Tim D and EuroCLOT Investigators, Investigators and Wellcome Trust Case Control Consortium 2, Trust Case Control Consortium 2 and MOnica Risk, Genetics, Archiving and Monograph, Risk, Genetics, Archiving and Monograph and MetaStroke, MetaStroke and International Stroke Genetics Consortium, Stroke Genetics Consortium and EuroCLOT Investigators and Wellcome Trust Case Control Consor and Int Stroke Genetics Consortium and MOnica Risk, Genetics, Archiving and Monograph and MetaStroke and International Stroke Genetics Consortium and Wellcome Trust Case Control Consortium 2 and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Annals of neurology, ISSN 0364-5134, 2013, Volume 73, Issue 1, pp. 16 - 31
Journal Article
Book
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, pp. e22542 - e22542
Background: Moyamoya disease is an idiopathic vascular disorder of intracranial arteries. Its susceptibility locus has been mapped to 17q25.3 in Japanese... 
MIDDLE CEREBRAL-ARTERY | WILLIS | VIRUS-INFECTION | ZEBRAFISH | SPONTANEOUS OCCLUSION | BIOLOGY | FIBROBLAST-GROWTH-FACTOR | LINKAGE ANALYSIS | CEREBROSPINAL-FLUID | EXPRESSION | CIRCLE | Moyamoya Disease - ethnology | Blood Vessels - metabolism | Humans | DNA, Complementary - genetics | 3' Untranslated Regions - genetics | Molecular Sequence Data | Male | Case-Control Studies | Gene Knockdown Techniques | Blood Vessels - physiopathology | Base Sequence | Cloning, Molecular | HEK293 Cells | Adult | Female | Genetic Predisposition to Disease - genetics | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Linkage Disequilibrium - genetics | Exons - genetics | Zebrafish | DNA Copy Number Variations - genetics | Open Reading Frames - genetics | Sequence Homology, Amino Acid | Exome - genetics | Animals | Adenosine Triphosphatases | Alleles | Ubiquitin-Protein Ligases - deficiency | Moyamoya Disease - physiopathology | HeLa Cells | Ubiquitin-Protein Ligases - genetics | Moyamoya Disease - genetics | Ubiquitin | Medical colleges | Disease susceptibility | Genetic aspects | Gene mutations | Genes | Transcription | Laboratories | Genomics | Chicken pox | Infections | Genomes | Single-nucleotide polymorphism | Family medical history | Neurosurgery | Carotid arteries | Arteries | Ubiquitination | Life sciences | Informatics | Ubiquitin-protein ligase | Linkage analysis | Lupus | Hypertension | Cytomegalovirus | Stroke | Moyamoya disease | Cytokines | Susceptibility | Blood vessels | Radiation therapy | Disease control | Patients | Loci | Studies | Environmental science | Genotyping | Mutation | Gene mapping | Adenosine triphosphatase | Veins & arteries | Index Medicus
Journal Article
by Helgadottir, Anna, MD, PhD and Gretarsdottir, Solveig, PhD and Thorleifsson, Gudmar, PhD and Holm, Hilma, MD and Patel, Riyaz S., MD and Gudnason, Thorarinn, MD, PhD and Jones, Gregory T., PhD and van Rij, Andre M., MD and Eapen, Danny J., MD and Baas, Annette F., PhD and Tregouet, David-Alexandre, PhD and Morange, Pierre-Emmanuel, MD and Emmerich, Joseph, MD, PhD and Lindblad, Bengt, MD, PhD and Gottsäter, Anders, MD, PhD and Kiemeny, Lambertus A., PhD and Lindholt, Jes S., MD, PhD and Sakalihasan, Natzi, MD, PhD and Ferrell, Robert E., PhD and Carey, David J., PhD and Elmore, James R., MD and Tsao, Philip S., PhD and Grarup, Niels, MD, PhD and Jørgensen, Torben, MD, DMSci and Witte, Daniel R., MD, PhD and Hansen, Torben, MD, PhD and Pedersen, Oluf, MD, DMSci and Pola, Roberto, MD, PhD and Gaetani, Eleonora, MD and Magnadottir, Hulda B., MD and Wijmenga, Cisca, PhD and Tromp, Gerard, PhD and Ronkainen, Antti, MD, PhD and Ruigrok, Ynte M., MD and Blankensteijn, Jan D and Mueller, Thomas, MD and Wells, Philip S., MD and Corral, Javier, PhD and Soria, Jose Manuel, PhD and Souto, Juan Carlos, MD, PhD and Peden, John F., PhD and Jalilzadeh, Shapour, MD, PhD and Mayosi, Bongani M., DPhil and Keavney, Bernard, MD and Strawbridge, Rona J., PhD and Sabater-Lleal, Maria, PhD and Gertow, Karl, PhD and Baldassarre, Damiano, PhD and Nyyssönen, Kristiina, PhD and Rauramaa, Rainer, MD, PhD and Smit, Andries J., MD, PhD and Mannarino, Elmo, MD and Giral, Philippe, MD and Tremoli, Elena, PhD and de Faire, Ulf, MD, PhD and Humphries, Steve E., PhD and Hamsten, Anders, MD, PhD and Haraldsdottir, Vilhelmina, MD and Olafsson, Isleifur, MD, PhD and Magnusson, Magnus K., MD and Samani, Nilesh J., MD and Levey, Allan I., MD, PhD and Markus, Hugh S., MD and Kostulas, Konstantinos, MD, PhD and Dichgans, Martin, MD and Berger, Klaus, MD and Kuhlenbäumer, Gregor, MD and Ringelstein, E. Bernd, MD and Stoll, Monika, PhD and Seedorf, Udo, PhD and Rothwell, Peter M., MD, PhD and Powell, Janet T., MD and Kuivaniemi, Helena, MD, PhD and Onundarson, Pall T., MD and Valdimarsson, Einar, MD and Matthiasson, Stefan E., MD, PhD and Gudbjartsson, Daniel F., PhD and Thorgeirsson, Guðmundur, MD, PhD and Quyyumi, Arshed A., MD and Watkins, Hugh, MD, PhD and Farrall, Martin, MD and Thorsteinsdottir, Unnur, PhD and Stefansson, Kari, MD, PhD and Lund University and Vascular Diseases - Clinical Research and Vaskulära sjukdomar - kliniska studier and Lunds universitet
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2012, Volume 60, Issue 8, pp. 722 - 729
Objectives The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene ( LPA ) on vascular diseases with different... 
Cardiovascular | Internal Medicine | atherosclerosis | genetic | association | thrombosis | lipoprotein(a) | INTIMA-MEDIA THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | MYOCARDIAL-INFARCTION | VASCULAR-DISEASE | WOMEN | PERIPHERAL ARTERIAL-DISEASE | ISCHEMIC-STROKE | SEVERITY | Severity of Illness Index | Myocardial Infarction - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Apolipoproteins A - genetics | Angiography | Carotid Intima-Media Thickness | Intracranial Aneurysm - genetics | Atherosclerosis - genetics | Humans | Risk Factors | Brain Ischemia - genetics | African Americans - genetics | Linear Models | Logistic Models | Aortic Aneurysm, Abdominal - genetics | Stroke - genetics | Venous Thromboembolism - genetics | Peripheral Arterial Disease - genetics | Age of Onset | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Odds Ratio | Medical colleges | Neurosciences | Stock options | Genes | Aneurysms | Coronary heart disease | Biometry | Lipoprotein A | Anopheles | Atherosclerosis | Medical genetics | Genetic research | Genetic aspects | Diabetes | Thromboembolism | Cardiology | Public health | Dementia | Stroke | Medical imaging | Values | Cardiovascular disease | Apolipoproteins | Thrombosis | Studies | Confidence intervals | Coronary vessels | Blood pressure | Drug therapy | Age | Methods | Index Medicus | Abridged Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, pp. e0185785 - e0185785
Background Hereditary thrombophilia (HT) is a genetic predisposition to thrombosis. Asian mutation spectrum of HT is different from Western ones. We... 
POPULATION | FACTOR-V-LEIDEN | RISK-FACTORS | MANAGEMENT | MULTIDISCIPLINARY SCIENCES | PULMONARY-EMBOLISM | MUTATION | DEEP-VEIN THROMBOSIS | ANTITHROMBIN-III | PROTEIN-C | CARRIERS | Protein C Deficiency - complications | Conjunctivitis - genetics | Protein C Deficiency - physiopathology | Humans | Middle Aged | Plasminogen - genetics | Male | Antithrombin III Deficiency - genetics | Antithrombin III - genetics | Skin Diseases, Genetic - genetics | Thrombophilia - etiology | Protein S Deficiency - genetics | Thrombophilia - diagnosis | Antithrombin III Deficiency - physiopathology | Skin Diseases, Genetic - diagnosis | Adult | Female | Retrospective Studies | Antithrombin III Deficiency - complications | Protein S Deficiency - physiopathology | Skin Diseases, Genetic - complications | Antithrombin III Deficiency - diagnosis | Republic of Korea | Venous Thromboembolism - diagnosis | Thrombophilia - genetics | Gene Expression | Protein S Deficiency - complications | Protein S - genetics | Thrombophilia - physiopathology | Sequence Analysis, DNA | Venous Thromboembolism - etiology | Venous Thromboembolism - genetics | Skin Diseases, Genetic - physiopathology | Venous Thromboembolism - physiopathology | Conjunctivitis - physiopathology | Protein C Deficiency - diagnosis | Aged | Protein C Deficiency - genetics | Conjunctivitis - complications | Protein C - genetics | Protein S Deficiency - diagnosis | Conjunctivitis - diagnosis | Plasminogen - deficiency | Type 2 diabetes | Protein C | Genetic aspects | Research | Nucleotide sequencing | Health aspects | DNA sequencing | Hypertension | Anticoagulants | Stroke | Laboratories | Embolisms | Protein deficiency | Antithrombin | Patients | Thrombosis | Gene sequencing | Proteins | Medicine | Thrombophilia | Protein S | Genetics | Diabetes | Mutation | Thromboembolism | Cardiology | Health risk assessment | Deoxyribonucleic acid--DNA | Veins & arteries | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS Genetics, ISSN 1553-7390, 11/2016, Volume 12, Issue 11, pp. e1006314 - e1006314
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0164364 - e0164364
Discovery and validation of genetic variants that influence disease severity in children with sickle cell anemia (SCA) could lead to early identification of... 
MICROALBUMINURIA | MULTIDISCIPLINARY SCIENCES | HYDROXYUREA TREATMENT | SALUSIN-ALPHA | RISK | ADVERSE OUTCOMES | RENAL-DISEASE | DEFICIENT MICE | APOL1 | NEPHROPATHY | CHRONIC TRANSFUSION | Albuminuria - complications | Neutrophils - cytology | Lipoproteins, HDL - genetics | Prospective Studies | Humans | Male | Anemia, Sickle Cell - drug therapy | Genetic Variation | Albuminuria - diagnosis | Apolipoproteins - genetics | Female | Leukocyte Count | Child | Leukocytes - cytology | Glomerular Filtration Rate | Anemia, Sickle Cell - complications | Risk Factors | Receptors, Cell Surface - metabolism | Genotype | Transcription Factors - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | Phenotype | Adolescent | Apolipoprotein L1 | Duffy Blood-Group System - metabolism | Hydroxyurea - therapeutic use | Polymorphism, Single Nucleotide | Anemia, Sickle Cell - diagnosis | Duffy Blood-Group System - genetics | Anemia, Sickle Cell - genetics | Receptors, Cell Surface - genetics | Pediatrics | Care and treatment | Sickle cell anemia | Diabetic nephropathies | African Americans | Sickle cell anemia in children | Hydroxyurea | Risk factors | Genetic polymorphisms | Diseases | Preventive health services | Genetic markers | Genetic aspects | Children | Medicine, Preventive | Blood cell count | Therapy | Clinical trials | Gene polymorphism | Blood | Gene sequencing | Duffy antigen | Rodents | Bioindicators | Sickle cell disease | Medical research | Stroke | Filtration | Risk groups | Anemia | Mortality | Diabetes mellitus | Health risks | Risk analysis | Gene expression | Glomerular filtration rate | White blood cells | Studies | CD163 antigen | Genetic variance | Biomarkers | Polymorphism | Kidney transplantation | Index Medicus
Journal Article
by Ehret, Georg B and Munroe, Patricia B and Rice, Kenneth M and Bochud, Murielle and Johnson, Anew D and Chasman, Daniel I and Smith, Albert V and Tobin, Martin D and Verwoert, Germaine C and Hwang, Shih-Jen and Pihur, Vasyl and Vollenweider, Peter and O'Reilly, Paul F and Amin, Najaf and Bragg-Gresham, Jennifer L and Teumer, Alexander and Glazer, Nicole L and Launer, Lenore and Zhao, Jing Hua and Aulchenko, Yurii and Heath, Simon and Sõber, Siim and Parsa, Afshin and Luan, Jian'an and Arora, Pankaj and Dehghan, Abbas and Zhang, Feng and Lucas, Gavin and Hicks, Anew A and Jackson, Anne U and Peden, John F and Tanaka, Toshiko and Wild, Sarah H and Rudan, Igor and Igl, Wilmar and Milaneschi, Yuri and Parker, Alex N and Fava, Cristiano and Chambers, John C and Fox, Ervin R and Kumari, Meena and Go, Min Jin and van der Harst, Pim and Kao, Wen Hong Linda and Sjögren, Marketa and Vinay, D. G and Alexander, Myriam and Tabara, Yasuharu and Shaw-Hawkins, Sue and Whincup, Peter H and Liu, Yongmei and Shi, Gang and Kuusisto, Johanna and Tayo, Bamidele and Seielstad, Mark and Sim, Xueling and Nguyen, Khanh-Dung Hoang and Lehtimäki, Terho and Matullo, Giuseppe and Wu, Ying and Gaunt, Tom R and Onland-Moret, N. Charlotte and Cooper, Matthew N and Platou, Carl G. P and Org, Elin and Hardy, Rebecca and Dahgam, Santosh and Palmen, Jutta and Vitart, Veronique and Braund, Peter S and Kuznetsova, Tatiana and Uiterwaal, Cuno S. P. M and Adeyemo, Adebowale and Palmas, Walter and Campbell, Harry and Ludwig, Barbara and Tomaszewski, Maciej and Tzoulaki, Ioanna and Palmer, Nicholette D and Aspelund, Thor and Garcia, Melissa and Chang, Yen-Pei C and O'Connell, Jeffrey R and Steinle, Nanette I and Grobbee, Diederick E and Arking, Dan E and Kardia, Sharon L and Morrison, Alanna C and Hernandez, Dena and Najjar, Samer and McArdle, Wendy L and Hadley, David and Brown, Morris J and Connell, John M and Hingorani, Aroon D and Day, Ian N. M and Lawlor, Debbie A and Beilby, John P and Lawrence, Robert W and Clarke, Robert and ... and CHARGE-HF Consortium and EchoGen Consortium and KidneyGen Consortium and CARDIoGRAM Consortium and Int Consortium Blood Pressure Geno and CKDGen Consortium and International Consortium for Blood Pressure Genome-Wide Association Studies and EchoGen consortium and CHARGE-HF consortium and CARDIoGRAM consortium and The International Consortium for Blood Pressure Genome-Wide Association Studies and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Nature, ISSN 0028-0836, 2011, Volume 478, Issue 7367, pp. 103 - 109
Journal Article