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PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 7, p. e0177962
Adult neural crest stem-derived cells (NCSC) are of extraordinary high plasticity and promising candidates for use in regenerative medicine... 
PROGENITOR CELLS | MESENCHYMAL STROMAL CELLS | STEM-CELLS | TRUNK | MULTIDISCIPLINARY SCIENCES | PERIODONTAL-LIGAMENT | ONTOGENY | GENERATION | SKIN-DERIVED PRECURSORS | DIFFERENTIATION | MELANOCYTES | RNA-Binding Proteins - genetics | Humans | Adipose Tissue - cytology | Melanocytes - metabolism | Neurons - cytology | Receptors, Nerve Growth Factor - metabolism | Neural Stem Cells - cytology | Schwann Cells - cytology | Neural Crest - metabolism | Adipose Tissue - metabolism | Mesenchymal Stromal Cells - cytology | Snail Family Transcription Factors - genetics | Melanocytes - cytology | Nestin - genetics | Adult | Female | Cell Differentiation | Neurons - metabolism | Dermis - cytology | Nuclear Proteins - genetics | Biomarkers - metabolism | SOX9 Transcription Factor - metabolism | Gene Expression | Neural Crest - cytology | Dermis - metabolism | Snail Family Transcription Factors - metabolism | Microinjections | Bone Marrow Cells - cytology | Neural Crest - growth & development | Mesenchymal Stromal Cells - metabolism | Nuclear Proteins - metabolism | Schwann Cells - metabolism | Transcription Factor Brn-3A - metabolism | Chick Embryo | Nerve Tissue Proteins - genetics | Receptors, Nerve Growth Factor - genetics | Nerve Tissue Proteins - metabolism | Nestin - metabolism | Animals | Transcription Factor Brn-3A - genetics | Twist-Related Protein 1 - genetics | Twist-Related Protein 1 - metabolism | Neural Stem Cells - metabolism | SOX9 Transcription Factor - genetics | Bone Marrow Cells - metabolism | Mesenchymal Stem Cell Transplantation | RNA-Binding Proteins - metabolism | Adipose tissues | Comparative analysis | Skin | Neurosciences | Nestin | Adipose tissue | Leukocyte migration | Laboratories | Sox9 protein | Dermis | Melanocytes | Nervous system | Human tissues | Regeneration (physiology) | Cell adhesion & migration | Msi1 protein | Plasticity (neural) | Ethics | Immunology | Pathways | Surgery | Bone marrow | Hair | Hematology | Neurons | Tissue engineering | Schwann cells | Brn-3 protein | Gene expression | Embryos | Neural crest | Medicine | Regeneration | Human performance | Stromal cells | Stem cells | Cell migration | Dental pulp
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 466, Issue 7308, pp. 829 - 834
The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial and perivascular cells... 
PROGENITOR CELLS | OSTEOBLAST | OSTEOPONTIN | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | RECEPTOR | DIFFERENTIATION | NEURAL CREST | COOPERATION | EXPRESSION | Chondrocytes - cytology | Nestin | Multipotent Stem Cells - metabolism | Parathyroid Hormone - pharmacology | Cell Lineage - drug effects | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Multipotent Stem Cells - drug effects | Sympathetic Nervous System - physiology | Cell Division | Stromal Cells - drug effects | Osteoblasts - cytology | Hematopoietic Stem Cells - drug effects | Mesenchymal Stromal Cells - drug effects | Gene Expression Regulation - genetics | Osteoblasts - drug effects | Stromal Cells - metabolism | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | Stem Cell Niche - cytology | Nerve Tissue Proteins - metabolism | Granulocyte Colony-Stimulating Factor - pharmacology | Animals | Chemokine CXCL12 - metabolism | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Hematopoietic Stem Cells - cytology | Stem Cell Niche - metabolism | Mice | Stem Cell Niche - drug effects | Osteoblasts - metabolism | Intermediate Filament Proteins - metabolism | Mesenchymal Stem Cell Transplantation | Stromal Cells - cytology | Cell Movement | Physiological aspects | Genetic aspects | Research | Bone marrow cells | Gene expression | Osteoblasts | Hematopoietic stem cells | Studies | Proteins | Bone marrow | Rodents | Stem cells
Journal Article
Stem cells (Dayton, Ohio), ISSN 1549-4918, 2008, Volume 26, Issue 2, pp. 300 - 311
Placental tissue draws great interest as a source of cells for regenerative medicine because of the phenotypic plasticity of many of the cell types isolated from this tissue... 
Human placenta | Fetal membranes | Amnion | Mesenchymal stromal cells | Chorion | Fetal tolerance | OCULAR SURFACE | TISSUE-TRANSPLANTATION | mesenchymal stromal cells | BONE-MARROW | MEMBRANE TRANSPLANTATION | AMNIOTIC EPITHELIAL-CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | chorion | ONCOLOGY | fetal membranes | fetal tolerance | MESENCHYMAL PROGENITOR CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | human placenta | NEURAL RETINA | SPINAL-CORD-INJURY | HEMATOLOGY | CHORION CELLS | amnion | POTENTIAL SOURCE | Tissue Banks | Embryonic Stem Cells - cytology | Humans | Chorion - cytology | Mesenchymal Stromal Cells - immunology | Stem Cell Transplantation | Hematopoietic Stem Cells - immunology | Mesenchymal Stromal Cells - cytology | Placenta - cytology | Antigens, Surface - metabolism | Chorion - immunology | Female | Cell Differentiation | Colony-Forming Units Assay | Trophoblasts - cytology | Embryonic Stem Cells - immunology | Epithelial Cells - cytology | Placenta - immunology | Amnion - cytology | Immune Tolerance | Stromal Cells - immunology | Cell Separation - methods | Cell Adhesion | Pregnancy | Trophoblasts - immunology | Animals | Embryonic Stem Cells - transplantation | Epithelial Cells - immunology | Hematopoietic Stem Cells - cytology | Mice | Amnion - immunology | Stromal Cells - cytology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 40, pp. 12516 - 12521
Human pluripotent stem cell-based in vitro models that reflect human physiology have the potential to reduce the number of drug failures in clinical trials and offer a cost-effective approach... 
Organoid | Toxicology | Differentiation | Tissue engineering | Machine learning | toxicology | HUMAN NEOCORTEX | tissue engineering | DEVELOPMENTAL NEUROTOXICITY | differentiation | HUMAN BRAIN | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | FATTY-ACIDS | machine learning | CANCER | organoid | IN-VITRO | HUMAN CEREBRAL-CORTEX | MICROGLIA | GENE-EXPRESSION | Embryonic Stem Cells - metabolism | Microglia - metabolism | Embryonic Stem Cells - cytology | Humans | Brain - growth & development | Support Vector Machine | Neural Stem Cells - cytology | Xenobiotics - pharmacology | Brain - metabolism | Neurogenesis - genetics | Mesenchymal Stromal Cells - cytology | Xenobiotics - classification | Gene Expression Regulation, Developmental | Cell Differentiation | Neurogenesis - drug effects | Culture Media, Serum-Free - pharmacology | Gene Ontology | Polyethylene Glycols - pharmacology | Microglia - cytology | Mesenchymal Stromal Cells - drug effects | Brain - cytology | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Microglia - drug effects | Endothelial Cells - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Mesenchymal Stromal Cells - metabolism | Cell Communication - genetics | Macrophages - cytology | Pluripotent Stem Cells - metabolism | Macrophages - metabolism | Embryonic Stem Cells - drug effects | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Cell Communication - drug effects | Macrophages - drug effects | Hydrogels - pharmacology | Neural Stem Cells - metabolism | Endothelial Cells - drug effects | Biological Sciences
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 12, p. e112291
Neural crest cells (NCCs) are an embryonic migratory cell population with the ability to differentiate into a wide variety of cell types that contribute to the craniofacial skeleton, cornea, peripheral nervous system, and skin pigmentation... 
MAINTENANCE | BRANCHIAL ARCHES | MULTIDISCIPLINARY SCIENCES | MOUSE | PATIENT-SPECIFIC IPSCS | GENERATION | DIFFERENTIATION | INDUCTION | SPECIFICATION | PARAXIAL MESODERM | MELANOCYTES | Chondrocytes - cytology | Neural Crest - cytology | Cell Proliferation | Embryonic Stem Cells - cytology | Pluripotent Stem Cells - cytology | Oligonucleotide Array Sequence Analysis | Cells, Cultured - cytology | Humans | Cell Lineage | Cornea - metabolism | Bone Morphogenetic Proteins - metabolism | Insulin - metabolism | Mesenchymal Stromal Cells - cytology | Flow Cytometry | Endothelial Cells - cytology | Melanocytes - cytology | Cell Differentiation | Culture Media - chemistry | Induced Pluripotent Stem Cells - cytology | DNA, Complementary - metabolism | Transforming Growth Factor beta - metabolism | Osteogenesis | Fibroblasts - metabolism | Fibroblast growth factors | Skin | Transforming growth factors | Gene expression | Embryonic stem cells | Biopharmaceutics | Cell culture | Pediatrics | Cornea | Mesenchyme | Medical innovations | Embryo cells | Melanocytes | Nervous system | Neuronal-glial interactions | Cell growth | Epidermal growth factor | Surgery | Growth factors | Biomedical engineering | Fibroblast growth factor 2 | Peripheral nervous system | Tissue engineering | Insulin | Neural crest | Embryos | Pigmentation | Endothelial cells | Medicine | Organic chemistry | Inhibitors | Animal behavior | Stromal cells | Stem cells | Differentiation | Pluripotency | Cell migration | Inhibitory postsynaptic potentials | Media (culture)
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 2/2014, Volume 111, Issue 5, pp. 1915 - 1920
IL-15 is a cytokine critical for development, maintenance, and response of T cells, natural killer (NK... 
T lymphocytes | Spleen | Lymphocytes | Natural killer T cells | Stromal cells | Antibodies | Bone marrow | Inflammation | Lymph nodes | Research universities | Aging | Homeostasis | Differentiation | Thymus | thymus | INTERLEUKIN 15 | NATURAL-KILLER | ACTIVATION | differentiation | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | RECEPTOR | FIBROBLASTIC RETICULAR CELLS | homeostasis | TRANS-PRESENTATION | aging | EXPRESSION | T-CELLS | Inflammation - pathology | Mesoderm - drug effects | Mesoderm - cytology | Aging - immunology | Mucous Membrane - cytology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | Lymph Nodes - drug effects | Mucous Membrane - drug effects | Thymus Gland - metabolism | Lymphoid Tissue - drug effects | Spleen - growth & development | Bone Marrow Cells - cytology | Endothelial Cells - metabolism | Stromal Cells - metabolism | Thymus Gland - cytology | Lymph Nodes - metabolism | Lymphoid Tissue - metabolism | Spleen - cytology | Thymus Gland - drug effects | Lymph Nodes - cytology | Gene Knock-In Techniques | Mucous Membrane - metabolism | Lymphoid Tissue - cytology | Animals | Spleen - metabolism | T-Lymphocytes - cytology | Endothelial Cells - cytology | Interleukin-15 - metabolism | Lipopolysaccharides - pharmacology | Mice | Bone Marrow Cells - metabolism | Stromal Cells - cytology | Endothelial Cells - drug effects | Physiological aspects | Interleukin-15 | Research | Health aspects | Immunological research | Biological Sciences
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 3, p. e59354
Mesenchymal stem cells (MSCs) reside in almost all of the body tissues, where they undergo self-renewal and multi-lineage differentiation... 
ADHESION MOLECULE-1 | HUMAN PLACENTA | HUMAN BONE-MARROW | UMBILICAL-CORD | IFN-GAMMA | TOLERANCE | MULTIDISCIPLINARY SCIENCES | TNF-ALPHA | STROMAL CELLS | EXPRESSION | ADIPOSE-TISSUE | Humans | Umbilical Cord - cytology | Adipose Tissue - cytology | Adipocytes - cytology | Adipose Tissue - immunology | Chorion - cytology | Mesenchymal Stromal Cells - immunology | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - classification | T-Lymphocytes, Helper-Inducer - immunology | Bone Marrow Cells - immunology | T-Lymphocytes, Helper-Inducer - cytology | Chorion - immunology | Adult | Female | Osteocytes - immunology | Vascular Cell Adhesion Molecule-1 - genetics | Cell Differentiation | Adipocytes - immunology | Cytokines - immunology | Biomarkers - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Gene Expression | Bone Marrow Cells - cytology | Immunomodulation | Osteocytes - cytology | Umbilical Cord - immunology | Pregnancy | Cytokines - biosynthesis | Gene expression | Stem cells | B cells | Biological properties | Vascular cell adhesion molecule 1 | Mesenchyme | Laboratories | Tissues | Cell adhesion & migration | Biomedical materials | Rodents | Bone marrow | Tumor necrosis factor-TNF | Biocompatibility | Subpopulations | Cytokines | Hematology | Dendritic cells | Immunoregulation | Hospitals | Placenta | Engineering research | Umbilical cord | Differentiation | Blood diseases
Journal Article