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Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1262 - 1270
Profibrotic cells that develop upon injury generate permanent scar tissue and impair organ recovery, though their origin and fate are unclear. Here we show... 
MEDICINE, RESEARCH & EXPERIMENTAL | PERIPHERAL-NERVES | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER FIBROSIS | MESENCHYMAL STEM-CELLS | BETA | CELL BIOLOGY | SKELETAL-MUSCLE | IN-VIVO | MELTRIN ALPHA | SCHWANN-CELLS | NEURAL CREST | EXPRESSION | Ear, External - injuries | Freund's Adjuvant - toxicity | Stromal Cells - pathology | Ear, External - pathology | Muscle, Skeletal - metabolism | Muscle, Skeletal - injuries | Wound Healing | Gene Knockdown Techniques | Parabiosis | Myofibroblasts - metabolism | ADAM12 Protein | Ear, External - metabolism | ADAM Proteins - analysis | Collagen - biosynthesis | Receptor, Platelet-Derived Growth Factor alpha - analysis | Genes, Reporter | Myofibroblasts - pathology | Acute Disease | Dermis - metabolism | Specific Pathogen-Free Organisms | Leg Injuries - metabolism | Stromal Cells - metabolism | ADAM Proteins - deficiency | Cobra Cardiotoxin Proteins - toxicity | Mice, Transgenic | Adipocytes - pathology | Blood Vessels - cytology | Leg Injuries - pathology | Cell Lineage | Animals | Fibrosis | Dermis - pathology | Cicatrix - pathology | Dermis - injuries | Mice | Muscle, Skeletal - pathology | ADAM Proteins - genetics | Crosses, Genetic | Care and treatment | Growth | Stem cells | Genetic aspects | Research | Diagnosis | Gene expression | Cell differentiation | Proteins | Blood vessels | Signal transduction | Cell growth | Injuries | Index Medicus | Blood Vessels | Cobra Cardiotoxin Proteins | Dermis | Adipocytes | Cicatrix | Life Sciences | Stromal Cells | Immunology | Leg Injuries | ADAM Proteins | Ear, External | Freund's Adjuvant | Receptor, Platelet-Derived Growth Factor alpha | Collagen | Muscle, Skeletal | Myofibroblasts
Journal Article
Nature, ISSN 0028-0836, 04/2010, Volume 464, Issue 7290, pp. 852 - 857
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 78 - 81
Myeloproliferative neoplasms (MPNs) are diseases caused by mutations in the haematopoietic stem cell (HSC) compartment. Most MPN patients have a common... 
TYROSINE KINASE JAK2 | JAK2-V617F | ACTIVATING MUTATION | POLYCYTHEMIA-VERA | BONE | MULTIDISCIPLINARY SCIENCES | Neuroprotective Agents - therapeutic use | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Sympathetic Nervous System - drug effects | Humans | Hematopoietic Stem Cells - pathology | Myeloproliferative Disorders - pathology | Sympathetic Nervous System - physiopathology | Adrenergic beta-3 Receptor Agonists - pharmacology | Neuroprotective Agents - pharmacology | Interleukin-1beta - metabolism | Neoplastic Stem Cells - pathology | Female | Sympathetic Nervous System - pathology | Schwann Cells - drug effects | Hematopoietic Stem Cells - drug effects | Nerve Fibers - pathology | Mesenchymal Stromal Cells - drug effects | Stem Cell Niche | Janus Kinase 2 - genetics | Nerve Fibers - drug effects | Schwann Cells - pathology | Myeloproliferative Disorders - drug therapy | Receptors, Adrenergic, beta-3 - metabolism | Disease Progression | Neoplasms - drug therapy | Nestin - metabolism | Adrenergic beta-3 Receptor Agonists - therapeutic use | Animals | Mice | Mesenchymal Stromal Cells - pathology | Neoplasms - pathology | Complications and side effects | Development and progression | Health aspects | Peripheral nerve diseases | Hematopoietic stem cells | Myeloproliferative disorders | Tumors | Studies | Mutation | Kinases | Rodents | Stem cells | Apoptosis | Index Medicus
Journal Article
Cell Stem Cell, ISSN 1934-5909, 11/2016, Volume 19, Issue 5, pp. 613 - 627
Mesenchymal niche cells may drive tissue failure and malignant transformation in the hematopoietic system, but the underlying molecular mechanisms and... 
microenvironment | leukemia | inflammation | mesenchymal | hematopoietic stem cell | shwachman-diamond syndrome | niche | cancer | myelodysplastic syndrome (MDS) | S100A8 | PROGENITOR CELLS | OXIDATIVE DNA-DAMAGE | GENE | SBDS | MUTATIONS | SHWACHMAN-DIAMOND-SYNDROME | MYELODYSPLASTIC CELLS | STROMAL CELLS | EXPRESSION | DEFICIENCY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Bone and Bones - pathology | Inflammation - pathology | Leukemia - pathology | Oxidative Stress | Humans | Hematopoietic Stem Cells - pathology | Precancerous Conditions - metabolism | Leukemia - metabolism | S100 Proteins - genetics | Lipomatosis - pathology | Gene Deletion | Integrases - metabolism | Precancerous Conditions - pathology | Toll-Like Receptors - metabolism | Stem Cell Niche | Pathogen-Associated Molecular Pattern Molecules - metabolism | Signal Transduction | Exocrine Pancreatic Insufficiency - pathology | Risk Factors | Tumor Suppressor Protein p53 - metabolism | Mesenchymal Stromal Cells - metabolism | S100 Proteins - metabolism | Treatment Outcome | Hematopoietic Stem Cells - metabolism | Mitochondria - metabolism | Bone Marrow Diseases - pathology | Disease Progression | Transcription Factors - metabolism | Animals | Proteins - metabolism | DNA Repair | Sp7 Transcription Factor | Mice | DNA Damage | Mesenchymal Stromal Cells - pathology | Bone and Bones - abnormalities | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
British Journal of Cancer, ISSN 0007-0920, 03/2015, Volume 112, Issue 6, pp. 1067 - 1075
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2018, Volume 24, Issue 8, pp. 1277 - 1289
Journal Article