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Circulation, ISSN 0009-7322, 08/2011, Volume 124, Issue 7, pp. 796 - 805
Background-Cardiomyocytes use Ca2+ not only in excitation-contraction coupling but also as a signaling molecule promoting, for example, cardiac hypertrophy. It... 
gene therapy | calcium | STIM1 protein human | myocytes cardiac | hypertrophy | RAT CARDIOMYOCYTES | RNA INTERFERENCE | myocytes, cardiac | CARDIOMYOCYTE HYPERTROPHY | OPERATED CA2+ ENTRY | CARDIAC & CARDIOVASCULAR SYSTEMS | MOUSE HEART | VENTRICULAR MYOCYTES | ACTIVATES CRAC CHANNELS | CAPACITATIVE CALCIUM-ENTRY | TRPC CHANNELS | STIM1 | STIM1 protein, human | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Age Factors | Membrane Glycoproteins - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Cardiomegaly - pathology | Membrane Glycoproteins - physiology | Adenoviridae - genetics | Caffeine - pharmacology | Sarcolemma - metabolism | Animals, Newborn | Stromal Interaction Molecule 1 | Gene Transfer Techniques | Calcium Channels | Cells, Cultured | Enzyme Inhibitors - pharmacology | Gene Silencing | Cardiomegaly - physiopathology | Phosphodiesterase Inhibitors - pharmacology | Rats | Mice, Transgenic | Membrane Glycoproteins - genetics | Myocytes, Cardiac - pathology | Patch-Clamp Techniques | Animals | Myocytes, Cardiac - drug effects | Calcium Signaling - drug effects | Myocytes, Cardiac - physiology | Thapsigargin - pharmacology | Mice | Cardiomegaly - metabolism | Physiological aspects | Heart enlargement | Research | Life Sciences | Human health and pathology | Santé publique et épidémiologie | Cardiology and cardiovascular system
Journal Article
Journal Article
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 04/2019, Volume 18, Issue 6-7, pp. 682 - 695
Background: Atherosclerosis (AS) is a major risk factor for cardiovascular disease. microRNAs play a key role in gene regulation in the formation and... 
atherosclerosis | stromal interaction molecule 1 | miR-185 | MIGRATION | OPERATED CA2+ ENTRY | ENDOTHELIAL DYSFUNCTION | LOW-DENSITY-LIPOPROTEIN | PROLIFERATION | MICRORNA-185 | OX-LDL | PLAQUE | CELL BIOLOGY | TUMOR-SUPPRESSOR | SMOOTH-MUSCLE-CELLS
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 22, pp. 8682 - 8687
Orai1 and stromal interaction molecule (STIM) 1 are critical components of Ca²⁺ release-activated Ca²⁺ (CRAC) channels. Orai1 is a pore subunit of CRAC... 
T lymphocytes | Proteins | Calcium | HeLa cells | Fluorescence | Amino acids | Cell membranes | Sensors | Phosphatidylinositols | Truncation | Calcium-binding proteins | Total internal reflection fluorescence microscopy | Calcium release-activated calcium channel | Store-operated calcium entry | calcium release-activated calcium channel | ASPARTYL BETA-HYDROXYLASE | MULTIDISCIPLINARY SCIENCES | store-operated calcium entry | SENSOR | FUNCTIONAL-CHARACTERIZATION | ACTIVATES CRAC CHANNELS | calcium-binding proteins | CA2+ STORE DEPLETION | CALCIUM-ENTRY | total internal reflection fluorescence microscopy | ENDOPLASMIC-RETICULUM | PROTEINS | PLASMA MEMBRANE JUNCTIONS | T-CELLS | Calcium Channels - metabolism | Calcium - metabolism | Humans | Endoplasmic Reticulum - metabolism | Immunoblotting | Mixed Function Oxygenases - metabolism | EF Hand Motifs - genetics | Neoplasm Proteins - metabolism | HEK293 Cells | Muscle Proteins - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Calcium Channels - genetics | Calcium-Binding Proteins - metabolism | Stromal Interaction Molecule 1 | Jurkat Cells | Membrane Proteins - genetics | ORAI1 Protein | Protein Transport | Muscle Proteins - genetics | Protein Binding | Luminescent Proteins - genetics | HeLa Cells | Mutation | Mixed Function Oxygenases - genetics | Microscopy, Fluorescence | Calcium-Binding Proteins - genetics | Luminescent Proteins - metabolism | Biological Sciences
Journal Article
Journal Article