Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5373) 5373
Book Chapter (40) 40
Newspaper Article (14) 14
Book / eBook (13) 13
Dissertation (13) 13
Magazine Article (10) 10
Conference Proceeding (5) 5
Archival Material (4) 4
Reference (4) 4
Publication (3) 3
Government Document (2) 2
Microfilm (1) 1
Newsletter (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (3609) 3609
strychnine - pharmacology (2652) 2652
strychnine (1856) 1856
science & technology (1762) 1762
life sciences & biomedicine (1620) 1620
rats (1403) 1403
male (1353) 1353
biological and medical sciences (991) 991
neurosciences & neurology (887) 887
neurosciences (880) 880
mice (807) 807
humans (731) 731
cats (679) 679
female (639) 639
old medline (605) 605
bicuculline - pharmacology (563) 563
fundamental and applied biological sciences. psychology (559) 559
in vitro techniques (528) 528
glycine - pharmacology (495) 495
picrotoxin - pharmacology (494) 494
electric stimulation (477) 477
glycine agents - pharmacology (461) 461
glycine (450) 450
medical sciences (449) 449
neurons - drug effects (433) 433
electrophysiology (429) 429
vertebrates: nervous system and sense organs (404) 404
pharmacology & pharmacy (371) 371
seizures - chemically induced (358) 358
dose-response relationship, drug (347) 347
neurons - physiology (320) 320
action potentials - drug effects (301) 301
rats, sprague-dawley (299) 299
time factors (295) 295
pharmacology. drug treatments (294) 294
glycine - metabolism (293) 293
gaba antagonists - pharmacology (292) 292
physiology (291) 291
research (282) 282
spinal cord - physiology (277) 277
chemistry (263) 263
membrane potentials - drug effects (257) 257
rabbits (255) 255
spinal cord - drug effects (251) 251
synaptic transmission - drug effects (246) 246
strychnine - metabolism (239) 239
rats, inbred strains (237) 237
gamma-aminobutyric acid - pharmacology (232) 232
strychnine - analogs & derivatives (230) 230
central nervous system (222) 222
gaba (220) 220
electroencephalography (212) 212
patch-clamp techniques (207) 207
physical sciences (204) 204
rats, wistar (198) 198
neural inhibition - drug effects (196) 196
toxicology (196) 196
neuropharmacology (192) 192
pentylenetetrazole - pharmacology (191) 191
biochemistry & molecular biology (190) 190
cerebral cortex - drug effects (189) 189
excitatory amino acid antagonists - pharmacology (188) 188
spinal cord (185) 185
synapses - physiology (184) 184
strychnine - analysis (183) 183
strychnine - poisoning (183) 183
strychnine - chemistry (176) 176
pentylenetetrazole (175) 175
motor neurons - physiology (174) 174
animals, newborn (172) 172
evoked potentials - drug effects (171) 171
anticonvulsants - pharmacology (170) 170
picrotoxin (169) 169
receptors, glycine - metabolism (169) 169
strychnine - administration & dosage (169) 169
pharmacology (168) 168
nervous system (166) 166
strychnine - antagonists & inhibitors (163) 163
strychnine - toxicity (161) 161
seizures (159) 159
bicuculline (155) 155
brucine (155) 155
electroshock (155) 155
neurons (155) 155
receptors, glycine - antagonists & inhibitors (155) 155
receptors, glycine (153) 153
neural inhibition - physiology (152) 152
glycine - physiology (151) 151
cells, cultured (148) 148
cerebral cortex - physiology (148) 148
synapses - drug effects (148) 148
drug interactions (147) 147
motor neurons - drug effects (146) 146
alkaloids (143) 143
aminobutyrates - pharmacology (143) 143
glycine - antagonists & inhibitors (141) 141
spinal cord - cytology (135) 135
glycine receptor (134) 134
research article (134) 134
kinetics (131) 131
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4631) 4631
Russian (317) 317
German (171) 171
French (149) 149
Italian (109) 109
Japanese (94) 94
Chinese (82) 82
Spanish (18) 18
Polish (16) 16
Czech (13) 13
Hungarian (10) 10
Ukrainian (9) 9
Dutch (6) 6
Romanian (6) 6
Bulgarian (5) 5
Portuguese (4) 4
Serbian (3) 3
Persian (2) 2
Swedish (2) 2
Croatian (1) 1
Korean (1) 1
Lithuanian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text LC–MS/MS determination and comparative pharmacokinetics of strychnine, brucine and their metabolites in rat plasma after intragastric administration of each monomer and the total alkaloids from Semen Strychni
by Lin, Aihua and Su, Xiaochun and She, Dan and Qiu, Kuncheng and He, Qianmei and Liu, Yiming
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, ISSN 1570-0232, 01/2016, Volume 1008, pp. 65 - 73
Brucine | Strychnine N-oxide | Strychnine | Brucine N-oxide | Pharmacokinetics | Monomer | LC–MS/MS | The total strychnos alkaloids | Rat plasma | LC-MS/MS | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Animals | Strychnine - pharmacokinetics | Strychnine - blood | Rats | Loganiaceae - chemistry | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Strychnine - administration & dosage | Strychnine - analogs & derivatives | Metabolites | Comparative analysis | Alkaloids | Liquid chromatography | Precipitation (Meteorology) | Mass spectrometry | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
by Huang, Xin and Chen, Hao and Michelsen, Klaus and Schneider, Stephen and Shaffer, Paul L
Nature (London), ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 277 - 280
Strychnine - chemistry | Humans | Models, Molecular | Substrate Specificity | Crystallography, X-Ray | Strychnine - pharmacology | Receptors, Glycine - antagonists & inhibitors | Strychnine - metabolism | Receptors, Glycine - chemistry | Receptors, Glycine - metabolism | Binding Sites | Protein Multimerization - drug effects | Ion Channel Gating - drug effects | Protein Structure, Tertiary - drug effects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Modified porphyrin-brucine conjugated to gold nanoparticles and their application in photodynamic therapy
by Záruba, Kamil and Králová, Jarmila and ezanka, Pavel and Pou ková, Pavla and Veverková, Lenka and Král, Vladimír
Organic & biomolecular chemistry, ISSN 1477-0520, 7/2010, Volume 8, Issue 14, pp. 322 - 326
Physical Sciences | Chemistry | Chemistry, Organic | Science & Technology | Gold - chemistry | Cell Death - radiation effects | Photochemotherapy - methods | Solvents - chemistry | Strychnine - chemistry | Humans | Metal Nanoparticles - chemistry | Porphyrins - chemistry | Strychnine - pharmacology | Alkylation | Strychnine - therapeutic use | Neoplasms - drug therapy | Strychnine - analogs & derivatives | Animals | Strychnine - metabolism | Biological Transport | Intracellular Space - metabolism | Cell Line, Tumor | Mice | Cell Death - drug effects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Is There No End to the Total Syntheses of Strychnine? Lessons Learned in Strategy and Tactics in Total Synthesis
by Cannon, Jeffrey S and Overman, Larry E
Angewandte Chemie (International ed.), ISSN 1433-7851, 04/2012, Volume 51, Issue 18, pp. 4288 - 4311
natural products | synthesis strategy | strychnine | total synthesis | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Molecular Structure | Cyclization | Strychnine - chemistry | Aldehydes - chemistry | Strychnine - chemical synthesis | Index Medicus | Alkaloids | Tactics | Synthesis | Strategy | Strychnine | Evolution | Community relations | Indoles
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway
by Shu, Guangwen and Mi, Xue and Cai, Jian and Zhang, Xinlin and Yin, Wu and Yang, Xinzhou and Li, You and Chen, Lvyi and Deng, Xukun
Toxicology letters, ISSN 0378-4274, 10/2013, Volume 222, Issue 2, pp. 91 - 101
Brucine | Hepatocellular carcinoma | Metastasis | Hypoxia inducible factor 1 | Life Sciences & Biomedicine | Toxicology | Science & Technology | Humans | Male | Neoplasm Proteins - antagonists & inhibitors | Carcinoma, Hepatocellular - secondary | Neoplasm Proteins - metabolism | Strychnos nux-vomica - chemistry | Hypoxia-Inducible Factor 1 - metabolism | Hypoxia-Inducible Factor 1 - genetics | Dose-Response Relationship, Drug | Antineoplastic Agents, Phytogenic - administration & dosage | Carcinoma, Hepatocellular - drug therapy | Lung Neoplasms - secondary | China | Animals, Outbred Strains | Seeds - chemistry | Gene Expression Regulation, Neoplastic - drug effects | Antineoplastic Agents, Phytogenic - therapeutic use | Neoplasm Proteins - genetics | Antineoplastic Agents, Phytogenic - adverse effects | Liver Neoplasms - drug therapy | Strychnine - pharmacology | Random Allocation | Strychnine - administration & dosage | Strychnine - therapeutic use | Strychnine - analogs & derivatives | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Ethnopharmacology | Animals | Strychnine - adverse effects | Lung Neoplasms - prevention & control | Cell Line, Tumor | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Hypoxia-Inducible Factor 1 - antagonists & inhibitors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text A Short Formal Total Synthesis of Strychnine with a Samarium Diiodide Induced Cascade Reaction as the Key Step
by Beemelmanns, Christine and Reissig, Hans‐Ulrich
Angewandte Chemie (International ed.), ISSN 1433-7851, 10/2010, Volume 49, Issue 43, pp. 8021 - 8025
cascade reactions | indoles | ketyls | strychnine | samarium diiodide | Samarium diiodide | Strychnine | Indoles | Cascade reactions | Ketyls | Biological Products - chemical synthesis | Biological Products - chemistry | Samarium - chemistry | Strychnine - chemistry | Iodides - chemistry | Iodides - chemical synthesis | Strychnos - chemistry | Strychnine - chemical synthesis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Glycine receptor mechanism elucidated by electron cryo-microscopy
by Du, Juan and Lü, Wei and Wu, Shenping and Cheng, Yifan and Gouaux, Eric
Nature (London), ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 224 - 229
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Subunits - drug effects | Glycine - metabolism | Allosteric Regulation | Protein Conformation - drug effects | Receptors, Glycine - antagonists & inhibitors | Protein Subunits - metabolism | Ivermectin - metabolism | Strychnine - metabolism | Receptors, Glycine - agonists | Neurotransmitter Agents - pharmacology | Receptors, Glycine - metabolism | Binding Sites | Signal Transduction | Neurotransmitter Agents - metabolism | Models, Molecular | Zebrafish | Receptors, Glycine - ultrastructure | Strychnine - pharmacology | Ivermectin - pharmacology | Rotation | Cryoelectron Microscopy | Animals | Glycine - pharmacology | Protein Subunits - chemistry | Ion Channel Gating - drug effects | Biological research | Glycine receptors | Cryoelectron microscopy | Physiological aspects | Research | Molecular biology | Methods | Biology, Experimental | Signal transduction | Nervous system | Ligands | Neurotransmitters | Microscopy | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Oxime Ethers of (E)‑11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists
by Mohsen, Amal M. Y and Mandour, Yasmine M and Sarukhanyan, Edita and Breitinger, Ulrike and Villmann, Carmen and Banoub, Maha M and Breitinger, Hans-Georg and Dandekar, Thomas and Holzgrabe, Ulrike and Sotriffer, Christoph and Jensen, Anders A and Zlotos, Darius P
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 12/2016, Volume 79, Issue 12, pp. 2997 - 3005
Binding, Competitive | Ethers - chemical synthesis | Glycine - metabolism | Strychnine - chemistry | Humans | Molecular Conformation | Crystallography, X-Ray | Ethers - chemistry | Structure-Activity Relationship | Strychnine - pharmacology | Receptors, Glycine - antagonists & inhibitors | Strychnine - analogs & derivatives | Ethers - pharmacology | Oximes - chemistry | Animals | Inhibitory Concentration 50 | Oximes - pharmacology | Ligands | Molecular Structure | Binding Sites | Glycine - analysis | Strychnine - chemical synthesis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights