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toxicology (548) 548
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carcinogenesis, carcinogens and anticarcinogens (20) 20
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kinetics (19) 19
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metabolism (15) 15
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toxicity (15) 15
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oxidation-reduction (14) 14
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cell communication - drug effects (12) 12
effects of pollution and side effects of pesticides on vertebrates (12) 12
polychlorinated biphenyls (12) 12
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1. Full Text FEMA GRAS assessment of natural flavor complexes: Lavender, Guaiac Coriander-derived and related flavoring ingredients
by Fukushima, Shoji and Cohen, Samuel M and Eisenbrand, Gerhard and Gooderham, Nigel J and Guengerich, F. Peter and Hecht, Stephen S and Rietjens, Ivonne M.C.M and Rosol, Thomas J and Davidsen, Jeanne M and Harman, Christie L and Lu, Vivian and Taylor, Sean V
Food and chemical toxicology, ISSN 0278-6915, 11/2020, Volume 145
Sub-department of Toxicology | Toxicologie | Toxicology | Leerstoelgroep Toxicologie | VLAG
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2. Full Text In vitro-in silico-based analysis of the dose-dependent in vivo oestrogenicity of the soy phytoestrogen genistein in humans
by Boonpawa, Rungnapa and Spenkelink, Albertus and Punt, Ans and Rietjens, Ivonne M.C.M
British journal of pharmacology, ISSN 0007-1188, 2017, Volume 174, Issue 16, pp. 2739 - 2757
BU Toxicologie Bioassays & Novel Foods | Toxicologie | Toxicology | Leerstoelgroep Toxicologie | RIKILT - BU Toxicologie Bioassays & Novel Foods | VLAG | BU Toxicologie, Novel Foods & Agroketens | Sub-department of Toxicology | BU Toxicology, Novel Foods & Agrochains | BU Toxicology Bioassays & Novel Foods | RIKILT - BU Toxicology Bioassays & Novel Foods | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Genistein - blood | Genistein - pharmacokinetics | Isoflavones - blood | Humans | Liver - metabolism | Phytoestrogens - pharmacokinetics | Male | Glucuronides - blood | Phytoestrogens - blood | Dose-Response Relationship, Drug | Models, Biological | Computer Simulation | Female | Intestine, Small - metabolism | Metabolites | Analysis | Isoflavones | Soybeans | Dosimeters | Diet | Genistein | Predictions | Mathematical models | Dosimetry | Index Medicus | Research Papers | Research Paper | WIMEK
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3. Full Text Selecting the dose metric in reverse dosimetry based QIVIVE : Reply to: ‘Comment on ‘Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine’ by Ning et al
by Rietjens, Ivonne M.C.M and Ning, Jia and Chen, Lu and Wesseling, Sebastiaan and Strikwold, Marije and Louisse, Jochem
Archives of toxicology, ISSN 0340-5761, 2019, Volume 93, Issue 5, pp. 1467 - 1469
BU Toxicologie Bioassays & Novel Foods | Toxicologie | Toxicology | Leerstoelgroep Toxicologie | RIKILT - BU Toxicologie Bioassays & Novel Foods | VLAG | BU Toxicologie, Novel Foods & Agroketens | Sub-department of Toxicology | BU Toxicology, Novel Foods & Agrochains | WIMEK | BU Toxicology Bioassays & Novel Foods | RIKILT - BU Toxicology Bioassays & Novel Foods
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4. Full Text Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity
by Walczak, Agata P and Kramer, Evelien and Hendriksen, Peter J. M and Tromp, Peter and Helsper, Johannes P. F. G and van der Zande, Meike and Rietjens, Ivonne M. C. M and Bouwmeester, Hans
Nanotoxicology, ISSN 1743-5390, 5/2015, Volume 9, Issue 4, pp. 453 - 461
3Rs principle | characterization | surface properties | protein corona | mucus | BU Toxicologie Bioassays & Novel Foods | Toxicologie | Toxicology | Leerstoelgroep Toxicologie | RIKILT - BU Toxicologie Bioassays & Novel Foods | BU Toxicologie, Novel Foods & Agroketens | PRI BIOS Applied Metabolic Systems | Sub-department of Toxicology | BU Toxicology, Novel Foods & Agrochains | BIOS Applied Metabolic Systems | BU Toxicology Bioassays & Novel Foods | RIKILT - BU Toxicology Bioassays & Novel Foods | Characterization | Surface properties | Mucus | Protein corona | Science & Technology - Other Topics | Nanoscience & Nanotechnology | Life Sciences & Biomedicine | Science & Technology | Intestines - drug effects | Cell Line | Microscopy, Electron, Scanning | Biological Transport | Models, Biological | Coculture Techniques | Humans | Intestines - metabolism | Polystyrenes - pharmacokinetics | Polystyrenes - toxicity | In Vitro Techniques | Nanoparticles - toxicity | Index Medicus | Polystyrene resins | Surgical implants | Charging | Biomedical materials | In vivo testing | In vivo tests | In vitro testing
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5. Full Text Dynamic in vitro intestinal barrier model coupled to chip-based liquid chromatography mass spectrometry for oral bioavailability studies
by Santbergen, M.J.C and Zande, van der, M and Gerssen, A and Bouwmeester, H and Nielen, M.W.F
Analytical and bioanalytical chemistry, ISSN 1618-2642, 2020, Volume 412, Issue 5, pp. 1111 - 1122
BU Contaminanten & Toxines | Toxicologie | Organische Chemie | RIKILT - BU Toxicologie Bioassays & Novel Foods | BU Toxicologie, Novel Foods & Agroketens | RIKILT - Business unit Contaminanten & Toxines | BU Toxicology, Novel Foods & Agrochains | Laboratory for Organic Chemistry | BU Contaminants & Toxins | RIKILT - Sample Administration and Coordination | RIKILT - Business unit Contaminants & Toxins | RIKILT - Monsteradministratie & Coördinatie | RIKILT - BU Toxicology Bioassays & Novel Foods | BU Toxicologie Bioassays & Novel Foods | Toxicology | Leerstoelgroep Toxicologie | VLAG | Laboratorium voor Organische chemie | Sub-department of Toxicology | Monsteradministratie & Coördinatie | BU Toxicology Bioassays & Novel Foods | Organic Chemistry | Caco-2 Cells | Ergotamine - pharmacokinetics | Intestinal Mucosa - metabolism | Limit of Detection | Granisetron - administration & dosage | Administration, Oral | Humans | Granisetron - pharmacokinetics | Verapamil - pharmacokinetics | Biological Availability | Lab-On-A-Chip Devices | Permeability | Verapamil - administration & dosage | HT29 Cells | Models, Biological | Spectrometry, Mass, Electrospray Ionization - methods | Biotransformation | Chromatography, Liquid - methods | In Vitro Techniques | Tandem Mass Spectrometry - methods | Ergotamine - administration & dosage | Liquid chromatography | Mass spectrometry | Detectors | Spectroscopy | On-line systems | Mass spectroscopy | Bioavailability | Quadrupoles | Chromatography | Biological models (mathematics) | Intestine | Ergotamine | Biocompatibility | Verapamil | Toxins | Scientific imaging | Pretreatment | Internet | Transport | Index Medicus | Intestinal barrier | Oral bioavailability | Research Paper | Gut-on-a-chip | Chip-based liquid chromatography
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6. Full Text Corrigendum to ‘Embryotoxic and pharmacologic potency ranking of six azoles in the rat whole embryo culture by morphological and transcriptomic analysis’ [Toxicol. Appl. Pharmacol., 322 (2017) 15–26]
by Dimopoulou, Myrto and Verhoef, Aart and Pennings, Jeroen and van Ravenzwaay, Bennard and Rietjens, Ivonne M.C.M and Piersma, Aldert H
Toxicology and applied pharmacology, ISSN 0041-008X, 09/2018, Volume 355, pp. 287 - 287
Sub-department of Toxicology | Toxicologie | Toxicology | Leerstoelgroep Toxicologie | VLAG | WIMEK
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7. Full Text Assuring safety without animal testing concept (ASAT). Integration of human disease data with in vitro data to improve toxicology testing
by Stierum, Rob and Aarts, Jac and Boorsma, André and Bosgra, Sieto and Caiment, Florian and Ezendam, Janine and Greupink, Rick and Hendriksen, Peter and Soeteman-Hernandez, Lya G and Jennen, Danyel and Kleinjans, Jos and Kroese, Dinant and Kuper, Frieke and van Loveren, Henk and Monshouwer, Mario and Russel, Frans and van Someren, Eugene and Tsamou, Maria and Groothuis, Geny
Toxicology letters, ISSN 0378-4274, 09/2014, Volume 229, Issue Supplement (10 September 2014), pp. S4 - S4
Sub-department of Toxicology | Extern overig | Extern other
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8. Full Text Environmental Occurrence, Analysis, and Toxicology of Toxaphene Compounds
by Henk-Jan de Geus and Harrie Besselink and Abraham Brouwer and Jarle Klungsøyr and Brendan McHugh and Eugene Nixon and Gerhard G. Rimkus and Peter G. Wester and Jacob de Boer
Environmental health perspectives, ISSN 0091-6765, 2/1999, Volume 107, Issue 1, pp. 115 - 144
Chemical hazards | Toxicology | Chemosphere | Marine fishes | Congeners | Liver | Pesticides | Environmental health | Lakes | Enantiomers | Freshwater fishes | Toxaphene | Camphenes | Analysis | Legislation | Nomenclature | Individual congeners | Occurrence | Chlorinated bornanes | Public, Environmental & Occupational Health | Environmental Sciences & Ecology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Toxaphene - analysis | Endocrine Glands - drug effects | Kidney - drug effects | Stereoisomerism | Humans | Terminology as Topic | Thuja | Chromatography, Gas | Biodiversity | Toxaphene - chemistry | Brain - drug effects | Food Analysis | Animals | Liver - drug effects | Drugs, Chinese Herbal - chemistry | Mass Spectrometry | Toxaphene - toxicity | Index Medicus | Rijksinstituut voor Visserijonderzoek | Sub-department of Toxicology | Toxicologie | Netherlands Institute for Fisheries Research | Leerstoelgroep Toxicologie
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9. Full Text Implementation of a dynamic intestinal gut-on-a-chip barrier model for transport studies of lipophilic dioxin congeners
by Kulthong, Kornphimol and Duivenvoorde, Loes and Mizera, Barbara Z and Rijkers, Deborah and Dam, ten, Guillaume and Oegema, Gerlof and Puzyn, Tomasz and Bouwmeester, Hans and Zande, van der, Meike
RSC advances, ISSN 2046-2069, 2018, Volume 8, Issue 57, pp. 32440 - 32453
BU Contaminanten & Toxines | Toxicologie | RIKILT - BU Toxicologie Bioassays & Novel Foods | BU Toxicologie, Novel Foods & Agroketens | RIKILT - Business unit Contaminanten & Toxines | BU Toxicology, Novel Foods & Agrochains | RIKILT - BU Authenticity & Nutrients | BU Contaminants & Toxins | BU Authenticity & Nutrients | RIKILT - Business unit Contaminants & Toxins | RIKILT - BU Toxicology Bioassays & Novel Foods | BU Authenticity & Bioassays | BU Toxicologie Bioassays & Novel Foods | Toxicology | Leerstoelgroep Toxicologie | VLAG | Sub-department of Toxicology | RIKILT - BU Authenticiteit & Nutriënten | BU Authenticiteit & Nutrienten | BU Toxicology Bioassays & Novel Foods | BU Authenticiteit & Bioassays | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology
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10. Full Text Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment
by Chaudhari, U and Nemade, H and Wagh, V and Ellis, J.K and Srinivasan, S and Louisse, J
Archives of toxicology, ISSN 0340-5761, 2016, Volume 90, Issue 11, pp. 2763 - 2777
Sub-department of Toxicology | Toxicologie | Toxicology | Leerstoelgroep Toxicologie | VLAG | Biomedicine, general | Human stem cells derived cardiomyocytes | Heart failure | In vitro test system | Biomedicine | Environmental Health | Safety assessment | Occupational Medicine/Industrial Medicine | Transcriptomics | Cardiotoxicity | Pharmacology/Toxicology | Genomic biomarkers | Life Sciences & Biomedicine | Science & Technology | Anthracyclines - adverse effects | Drugs, Investigational - adverse effects | Myocytes, Cardiac - cytology | Oligonucleotide Array Sequence Analysis | Humans | Molecular Sequence Annotation | Cells, Cultured | Computational Biology | Antibiotics, Antineoplastic - adverse effects | Cardiotoxins - adverse effects | Gene Expression Profiling | Topoisomerase II Inhibitors - adverse effects | Reverse Transcriptase Polymerase Chain Reaction | Daunorubicin - adverse effects | Gene Expression Regulation - drug effects | Toxicity Tests, Chronic | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - metabolism | Drug Evaluation, Preclinical | Induced Pluripotent Stem Cells - cytology | Biomarkers, Pharmacological - metabolism | Real-Time Polymerase Chain Reaction | Doxorubicin - adverse effects | Mitoxantrone - adverse effects | Anthracyclines | Analysis | Genes | Genomics | Heart cells | Stem cells | Biological markers | Gene expression | Studies | Biomarkers | Genomes | Toxicity | Index Medicus | In Vitro Systems
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11. Full Text Translocation of positively and negatively charged polystyrene nanoparticles in an in vitro placental model
by Kloet, Samantha K and Walczak, Agata P and Louisse, Jochem and van den Berg, Hans H.J and Bouwmeester, Hans and Tromp, Peter and Fokkink, Remco G and Rietjens, Ivonne M.C.M
Toxicology in vitro, ISSN 0887-2333, 10/2015, Volume 29, Issue 7, pp. 1701 - 1710
Protein corona | BeWo b30 cells | Placental translocation | Physico-chemical characteristics | BU Toxicologie Bioassays & Novel Foods | Toxicologie | Physical Chemistry and Soft Matter | Toxicology | Leerstoelgroep Toxicologie | RIKILT - BU Toxicologie Bioassays & Novel Foods | BU Toxicologie, Novel Foods & Agroketens | Sub-department of Toxicology | BU Toxicology, Novel Foods & Agrochains | Rikilt B&T Toxicologie en Effectanalyse | BU Toxicology Bioassays & Novel Foods | RIKILT - BU Toxicology Bioassays & Novel Foods | Life Sciences & Biomedicine | Science & Technology | Placenta - metabolism | Pregnancy | Biological Transport | Polystyrenes - metabolism | Humans | Nanoparticles - metabolism | Cell Line, Tumor | Female | Nanoparticles | Polystyrene | Analysis | Index Medicus
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