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Journal of Neuroscience, ISSN 0270-6474, 04/2007, Volume 27, Issue 14, pp. 3663 - 3676
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2010, Volume 30, Issue 20, pp. 6838 - 6851
alpha-Synuclein is central in Parkinson's disease pathogenesis. Although initially alpha-synuclein was considered a purely intracellular protein, recent data... 
FIBRIL FORMATION | PROTEIN | MULTIVESICULAR BODIES | HUMAN PLASMA | ACTIVATES MICROGLIA | CONGO RED | ENDOPLASMIC-RETICULUM | FAMILIAL PARKINSONS-DISEASE | RELEASE | BODY FORMATION | NEUROSCIENCES | Molecular Weight | Serum - metabolism | Calcium - metabolism | Microscopy, Electron, Transmission - methods | Humans | Culture Media, Conditioned - chemistry | Cell Survival - genetics | Brefeldin A - pharmacology | Neurons - ultrastructure | Piperidines - pharmacology | Neurons - metabolism | alpha-Synuclein - genetics | Protein Synthesis Inhibitors - pharmacology | Exosomes - ultrastructure | Cell Survival - drug effects | Calcium - pharmacology | Immunoprecipitation - methods | Multivesicular Bodies - pathology | Endocytosis - drug effects | Rats | Microscopy, Confocal - methods | Analysis of Variance | Cell Line, Tumor | beta-Galactosidase - genetics | Multivesicular Bodies - drug effects | Temperature | Chromatography, High Pressure Liquid - methods | Culture Media, Conditioned - pharmacology | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Subcellular Fractions - ultrastructure | Transfection | Exosomes - physiology | beta-Galactosidase - metabolism | Presenilin-1 - pharmacology | Cell Death - drug effects | Cytotoxicity Tests, Immunologic - methods | Gene Expression Regulation, Neoplastic - drug effects | Neurons - drug effects | Neuroblastoma - pathology | Pyrazoles - pharmacology | Subcellular Fractions - drug effects | Multivesicular Bodies - ultrastructure | Cells, Cultured | Hydrogen Peroxide - pharmacology | Receptors, Transferrin - metabolism | Subcellular Fractions - metabolism | Peptides - pharmacology | Nerve Tissue Proteins - metabolism | Animals | Neuroblastoma - ultrastructure | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mass Spectrometry - methods | alpha-Synuclein - metabolism | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2010, Volume 13, Issue 5, pp. 567 - 576
Continuous turnover of intracellular components by autophagy is necessary to preserve cellular homeostasis in all tissues. Alterations in macroautophagy, the... 
NEURODEGENERATIVE DISEASE | RAT-LIVER | MODELS | CHAPERONE-MEDIATED AUTOPHAGY | MONITORING AUTOPHAGY | MUTANT HUNTINGTIN | DEGRADATION | ALPHA-SYNUCLEIN | HD MUTATION | NEUROSCIENCES | CELL-DEATH | Serum - metabolism | Microscopy, Electron, Transmission - methods | Microtubule-Associated Proteins - metabolism | Humans | Huntington Disease - pathology | Peptides - genetics | Apoptosis - genetics | Autophagy - physiology | Hepatocytes - metabolism | Vinca Alkaloids - metabolism | Mitochondria - ultrastructure | Subcellular Fractions - pathology | Autophagy - drug effects | Subcellular Fractions - ultrastructure | Serotonin Plasma Membrane Transport Proteins - genetics | Lysosomes - metabolism | Neurons - ultrastructure | Time Factors | Neurons - drug effects | Immunosuppressive Agents - pharmacology | Hepatocytes - drug effects | Huntington Disease - physiopathology | Disease Models, Animal | Lysosomes - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Mitochondria - pathology | Sirolimus - pharmacology | Subcellular Fractions - metabolism | Lysosomes - ultrastructure | Nerve Tissue Proteins - metabolism | Animals | Huntington Disease - genetics | Thapsigargin - pharmacology | Mice | Apoptosis - physiology | Autophagy (Cytology) | Gene mutations | Huntington's chorea | Cell death | Physiological aspects | Genetic aspects | Research | Index Medicus
Journal Article
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 09/2012, Volume 32, Issue 39, pp. 13555 - 13567
Journal Article
Nature Protocols, ISSN 1754-2189, 2014, Volume 9, Issue 3, pp. 586 - 596
Detection and quantification of fluorescently labeled molecules in subcellular compartments is a key step in the analysis of many cell biological processes.... 
CORRELATION-COEFFICIENT | COMPLEX | OBJECTS | EXPRESSION | COLOCALIZATION | BIOCHEMICAL RESEARCH METHODS | Subcellular Fractions - ultrastructure | Software | Image Processing, Computer-Assisted - methods | Microscopy, Fluorescence - methods | Usage | Research | Fluorescence microscopy | Quality of life | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15036 - 15052
AMPA receptors (AMPARs) are tetrameric ion channels assembled from GluA1-GluA4 subunits that mediate the majority of fast excitatory synaptic transmission in... 
PERISYNAPTIC SITES | GLUR1 SUBUNIT | KINASE-ANCHORING PROTEIN | LONG-TERM DEPRESSION | PKA PHOSPHORYLATION | DOWN-SYNDROME | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | POSTSYNAPTIC STRUCTURE | AKAP SIGNALING COMPLEXES | PHOSPHORYLATION SITES | Disks Large Homolog 4 Protein | Phosphorylation | Action Potentials - genetics | Electric Stimulation | Immunoprecipitation | Calcium - metabolism | Male | Excitatory Postsynaptic Potentials - drug effects | N-Methylaspartate - pharmacology | Quinoxalines - pharmacology | A Kinase Anchor Proteins - genetics | Subcellular Fractions - ultrastructure | Neuronal Plasticity - genetics | Calcineurin - genetics | Neuronal Plasticity - physiology | Neurons - ultrastructure | Female | Membrane Proteins - metabolism | Tetrodotoxin - pharmacology | Excitatory Postsynaptic Potentials - genetics | Receptors, AMPA - metabolism | Synapses - physiology | Mice, Inbred C57BL | Silver Staining | Cells, Cultured | Mice, Transgenic | Sodium Channel Blockers - pharmacology | Synapses - ultrastructure | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Hippocampus - cytology | Mutation - genetics | Serine - metabolism | Subcellular Fractions - metabolism | Patch-Clamp Techniques | Animals | Analysis of Variance | Guanylate Kinases - metabolism | Mice | In Vitro Techniques | Calcineurin - metabolism | Dendritic Spines - ultrastructure | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 09/2003, Volume 171, Issue 6, pp. 3154 - 3162
Toll-like receptor (TLR)3 recognizes dsRNA and transduces signals to activate NF-kappaB and IFN-beta promoter. Type I IFNs (IFN-alpha/beta) function as key... 
DOUBLE-STRANDED-RNA | INTERFERON-ALPHA | ACTIVATION | HUMAN PERIPHERAL-BLOOD | DROSOPHILA TOLL | II ANTIGEN PRESENTATION | INDUCTION | IMMUNOLOGY | MATURATION | EXPRESSION | BACTERIAL-DNA | Toll-Like Receptor 3 | Membrane Glycoproteins - metabolism | Monocytes - cytology | Dendritic Cells - immunology | Humans | Membrane Glycoproteins - biosynthesis | Monocytes - metabolism | Monocytes - immunology | Microscopy, Immunoelectron | Subcellular Fractions - ultrastructure | Toll-Like Receptors | Transfection | Plasma Cells - metabolism | Cell Membrane - metabolism | Receptors, Cell Surface - biosynthesis | Membrane Glycoproteins - immunology | Antibodies, Monoclonal - chemistry | Dendritic Cells - metabolism | Cell Line | Subcellular Fractions - immunology | Cells, Cultured | Membrane Glycoproteins - blood | Receptors, Cell Surface - metabolism | Receptors, Cell Surface - blood | Receptors, Cell Surface - immunology | Subcellular Fractions - metabolism | Precipitin Tests | Cell Differentiation - immunology | Animals | Up-Regulation - immunology | Dendritic Cells - ultrastructure | Transport Vesicles - metabolism | RNA, Double-Stranded - pharmacology | Cell Membrane - immunology | Dendritic Cells - cytology | Mice | Cytokines - biosynthesis | Transport Vesicles - ultrastructure | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article