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1. Full Text Nur77 gene expression levels were involved in different ACTH-secretion autonomy between Cushing's disease and subclinical Cushing's disease
by Tabuchi, Yukiko and Kitamura, Tetsuhiro and Fukuhara, Atsunori and Mukai, Kosuke and Onodera, Toshiharu and Miyata, Yugo and Hamasaki, Toshimitsu and Oshino, Satoru and Saitoh, Youichi and Morii, Eiichi and Otsuki, Michio and Shimomura, Iichiro
Endocrine Journal, ISSN 0918-8959, 2016, Volume 63, Issue 6, pp. 545 - 554
Cushing's disease (CD) and subclinical Cushing's disease (subCD) are both diseases caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas.... 
Nur77 | Adrenocorticotropic hormone | Pro-opiomelanocortin | Subclinical Cushing's disease | Cushing's disease | TPIT | CELLS | ACTIVATION | CORTICOTROPHS | INDUCTION | PROOPIOMELANOCORTIN | ENDOCRINOLOGY & METABOLISM | PITUITARY | T-BOX FACTOR | CARCINOMA | Index Medicus
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2. Full Text Nur77 gene expression levels were involved in different ACTH-secretion autonomy between Cushing's disease and subclinical Cushing's disease
by Tabuchi, Yukiko and Kitamura, Tetsuhiro and Fukuhara, Atsunori and Mukai, Kosuke and Onodera, Toshiharu and Miyata, Yugo and Hamasaki, Toshimitsu and Oshino, Satoru and Saitoh, Youichi and Morii, Eiichi and Otsuki, Michio and Shimomura, Iichiro
Endocrine Journal, ISSN 0918-8959, 2016
Cushing's disease (CD) and subclinical Cushing's disease (subCD) are both diseases caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas.... 
Adrenocorticotropic hormone | Cushing's disease | Nur77 | Pro-opiomelanocortin | Subclinical Cushing's disease
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3. Full Text Clinical significance of screening for subclinical Cushing's disease in patients with pituitary tumors
by Tamada, Daisuke and Kitamura, Tetsuhiro and Otsuki, Michio and Oshino, Satoru and Saitoh, Youichi and Shimomura, Iichiro
Endocrine Journal, ISSN 0918-8959, 2016, Volume 63, Issue 1, pp. 47 - 52
Cushing's syndrome (CS) is a clinical state caused by chronic excess of glucocorticoid, and results in hypertension, impaired glucose tolerance, and... 
Prevalence | Subclinical Cushing's disease | Metabolic disorders | ACTH-dependent hypercortisolism | ENDOCRINOLOGY & METABOLISM | FOLLOW-UP | ADRENAL INCIDENTALOMAS | HYPERCORTISOLISM | CARDIOVASCULAR RISK | Index Medicus
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4. Full Text Factors predicting the duration of adrenal insufficiency in patients successfully treated for Cushing disease and nonmalignant primary adrenal Cushing syndrome
by Prete, Alessandro and Paragliola, Rosa Maria and Bottiglieri, Filomena and Rota, Carlo Antonio and Pontecorvi, Alfredo and Salvatori, Roberto and Corsello, Salvatore Maria
Endocrine, ISSN 1355-008X, 3/2017, Volume 55, Issue 3, pp. 969 - 980
Successful treatment of Cushing syndrome causes transient or permanent adrenal insufficiency deriving from endogenous hypercortisolism-induced... 
Adrenal insufficiency | Medicine & Public Health | Science, Humanities and Social Sciences, multidisciplinary | Cushing syndrome | Internal Medicine | Diabetes | Adrenocortical adenoma | Cushing disease | Endocrinology | DIAGNOSIS | RISK-FACTORS | SUBCLINICAL HYPERCORTISOLISM | GLAND SCINTIGRAPHY | URINARY FREE CORTISOL | HYPOCORTISOLISM | GLUCOCORTICOID-RECEPTOR | MASS | ENDOCRINOLOGY & METABOLISM | TRANSSPHENOIDAL SURGERY | INCIDENTALOMA | Adrenocortical Adenoma - surgery | Cushing Syndrome - surgery | Prognosis | Age Factors | Adrenalectomy - adverse effects | Humans | Middle Aged | Adrenal Cortex Neoplasms - surgery | Male | Young Adult | Adrenal Insufficiency - etiology | Time Factors | Pituitary ACTH Hypersecretion - surgery | Adolescent | Adult | Female | Aged | Retrospective Studies | Complications and side effects | Development and progression | Care and treatment | Kidney diseases | Adrenalectomy | Nervous system diseases | Adrenocorticotropic hormone | Adrenal glands | Ketoconazole | Glucocorticoids | Etiology | Pituitary | Surgery | Hypothalamus | Family medical history | Index Medicus
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5. Full Text Accuracy of repeated measurements of late‐night salivary cortisol to screen for early‐stage recurrence of Cushing's disease following pituitary surgery
by Danet‐Lamasou, Marie and Asselineau, Julien and Perez, Paul and Vivot, Alexandre and Nunes, Marie‐Laure and Loiseau, Hugues and San‐Galli, François and Cherifi‐Gatta, Blandine and Corcuff, Jean‐Benoît and Tabarin, Antoine
Clinical Endocrinology, ISSN 0300-0664, 02/2015, Volume 82, Issue 2, pp. 260 - 266
ObjectiveThe performance of late-night salivary cortisol (LNSC) to accurately screen for postoperative recurrence of Cushing's disease (CD) at an early stage... 
DIAGNOSIS | STATES | SUBCLINICAL HYPERCORTISOLISM | ADRENAL INCIDENTALOMA | ENDOCRINOLOGY & METABOLISM | URINARY FREE CORTISOL | TRANSSPHENOIDAL SURGERY | DESMOPRESSIN TEST | CURE | TANDEM MASS-SPECTROMETRY | REPRODUCIBILITY | Recurrence | Adenoma - surgery | Prognosis | Humans | Middle Aged | Hydrocortisone - metabolism | Male | Saliva - chemistry | ACTH-Secreting Pituitary Adenoma - complications | Adenoma - metabolism | Adenoma - complications | ACTH-Secreting Pituitary Adenoma - surgery | Pituitary ACTH Hypersecretion - surgery | Adult | Female | Retrospective Studies | Adenoma - diagnosis | Reproducibility of Results | Pituitary ACTH Hypersecretion - etiology | ACTH-Secreting Pituitary Adenoma - metabolism | Specimen Handling - methods | Treatment Outcome | Circadian Rhythm | Disease Progression | ACTH-Secreting Pituitary Adenoma - diagnosis | Pituitary ACTH Hypersecretion - metabolism | Pituitary ACTH Hypersecretion - diagnosis | Saliva - metabolism | Hydrocortisone - analysis | Monitoring, Physiologic - methods | Neurosurgical Procedures - methods | Measurement | Relapse | Corticosteroids | Analysis | Surgery | Steroids | Diseases | Index Medicus
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6. Full Text Clinical significance of screening for subclinical Cushing's disease in patients with pituitary tumors
by Tamada, Daisuke and Kitamura, Tetsuhiro and Otsuki, Michio and Oshino, Satoru and Saitoh, Youichi and Shimomura, Iichiro
Endocrine Journal, ISSN 0918-8959, 2015
Cushing's syndrome (CS) is a clinical state caused by chronic excess of glucocorticoid, and results in hypertension, impaired glucose tolerance, and... 
Prevalence | ACTH-dependent hypercortisolism | Subclinical Cushing's disease | Metabolic disorders
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7. Full Text Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing's disease: A case report
by Takiguchi, Tomoko and Koide, Hisashi and Nagano, Hidekazu and Nakayama, Akitoshi and Fujimoto, Masanori and Tamura, Ai and Komai, Eri and Shiga, Akina and Kono, Takashi and Higuchi, Seiichiro and Sakuma, Ikki and Hashimoto, Naoko and Suzuki, Sawako and Miyabayashi, Yui and Ishiwatari, Norio and Horiguchi, Kentaro and Nakatani, Yukio and Yokote, Koutaro and Tanaka, Tomoaki
BMC Endocrine Disorders, ISSN 1472-6823, 09/2017, Volume 17, Issue 1, pp. 54 - 54
Background: A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) producing adenomas (GHoma) with... 
GHoma | Case report | Transcriptional factor | Subclinical Cushing's disease | Pituitary adenoma | TRANSCRIPTION | ACTH | GROWTH-HORMONE | ENDOCRINOLOGY & METABOLISM | EXPRESSION | MODULATION | ADRENOCORTICOTROPIC HORMONE | AXIS | Pituitary ACTH Hypersecretion - pathology | Transcription Factor Pit-1 - metabolism | Adenoma - genetics | Pituitary Neoplasms - genetics | Homeodomain Proteins - metabolism | Humans | Middle Aged | Male | Pituitary Neoplasms - pathology | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | Pituitary Neoplasms - complications | T-Box Domain Proteins - metabolism | Acromegaly - complications | Transcription Factor Pit-1 - genetics | Adenoma - complications | Pituitary ACTH Hypersecretion - complications | Adenoma - pathology | Acromegaly - pathology | Diabetes Mellitus, Type 2 - complications | Transcription factors | Pituitary gland tumors | Analysis | Cancer cells | Cushing syndrome | Acromegaly | Physiological aspects | Genetic aspects | Immunohistochemistry | Cell culture | Nuclear magnetic resonance--NMR | Transcription | Adrenal glands | Tissue culture | Proopiomelanocortin | Insulin-like growth factors | Coexistence | Adenoma | Pit1 protein | Prolactin | Surgery | Stains | Nervous system diseases | Tumor cells | Pituitary (anterior) | Gene expression | Beta2 protein | Thyroid-stimulating hormone | Adrenocorticotropic hormone | Growth hormones | Growth hormone | Tumors | Index Medicus
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8. Full Text PLURIHORMONAL PITUITARY ADENOMA: ACROMEGALY ASSOCIATED WITH SUBCLINICAL CUSHING'S DISEASE
by Korkmaz, H and Akarsu, E and Ozkaya, M and Ozturk, ZA and Tutar, E and Araz, M
ACTA ENDOCRINOLOGICA-BUCHAREST, ISSN 1841-0987, 07/2015, Volume 11, Issue 3, pp. 389 - 393
A 52-year old women was diagnosed with acromegaly 5 years ago, and transseptal transsphenoidal pituitary microsurgery has been performed. Later the patient did... 
plurihormonal pituitary adenoma | GROWTH-HORMONE | ENDOCRINOLOGY & METABOLISM | Acromegaly | ACTH | CLASSIFICATION | SECRETION | PROLACTIN | TUMORS | subclinical Cushing's disease | ADRENOCORTICOTROPIC HORMONE
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9. Full Text A somatotropin-producing pituitary adenoma with an isolated adrenocorticotropin-producing pituitary adenoma in a female patient with acromegaly, subclinical Cushing's disease and a left adrenal tumor
by Kobayashi, Yuki and Takei, Masahiro and Ohkubo, Yohsuke and Kakizawa, Yukinari and Matoba, Hisanori and Kumagai, Mieko and Takeda, Teiji and Suzuki, Satoru and Komatsu, Mitsuhisa
Endocrine Journal, ISSN 0918-8959, 2014, Volume 61, Issue 6, pp. 589 - 595
A 67-year-old female with hypertension and impaired glucose tolerance was admitted to our hospital because of a typical acromegalic appearance, including... 
Acromegaly | Double pituitary adenomas | Adrenal tumor | Subclinical Cushing's disease | Subclinical cushing's disease | CRITERIA | GROWTH-HORMONE | PIT-1 | ENDOCRINOLOGY & METABOLISM | ACTH | Index Medicus
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10. Full Text The Frequency of Type 2 Diabetic Patients who Meet the Endocrinological Screening Criteria of Subclinical Cushing's Disease
by MURAKAMI, Hiroshi and NIGAWARA, Takeshi and SAKIHARA, Satoru and KAGEYAMA, Kazunori and YAMASHITA, Maki and MATSUKI, Kota and TANABE, Jutaro and MATSUI, Jun and TAMASAWA, Naoki and SUDA, Toshihiro
Endocrine Journal, ISSN 0918-8959, 2010, Volume 57, Issue 3, pp. 267 - 272
Cushing's syndrome, including its mild form/state of adrenal-dependent subset (subclinical Cushing's syndrome; subCS), is known to enhance glucose intolerance,... 
Type 2 diabetes | Overnight dexamethasone suppression test | Midnight plasma cortisol level | Subclinical Cushing's disease | Subclinical cushing's disease | DIAGNOSIS | HOSPITALIZED-PATIENTS | DEXAMETHASONE-SUPPRESSION TEST | ENDOCRINOLOGY & METABOLISM | ADENOMA | MELLITUS | HYPERCORTISOLISM | CORTISOL | Index Medicus
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11. Full Text A Case of Acromegaly Associated with Subclinical Cushing's Disease
by TSUCHIYA, Kyoichiro and OHTA, Kazuki and YOSHIMOTO, Takanobu and DOI, Masaru and IZUMIYAMA, Hajime and HIRATA, Yukio
Endocrine Journal, ISSN 0918-8959, 2006, Volume 53, Issue 5, pp. 679 - 685
A 54-year-old man with type 2 diabetes was referred to our hospital for endocrine evaluation of acromegaly. Physical examination showed typical acromegalic... 
Acromegaly | Subclinical Cushing's disease | Pituitary adenoma | REGULATED SECRETION | VITRO | CELLS | subclinical Cushing's disease | GROWTH-HORMONE GH | 11-BETA-HYDROXYSTEROID DEHYDROGENASE | pituitary adenoma | PITUITARY-ADENOMA | ENDOCRINOLOGY & METABOLISM | acromegaly | EXPRESSION | ADRENOCORTICOTROPIC HORMONE | ADIPOSE-TISSUE | CORTISOL | Adenoma - diagnosis | Adenoma - surgery | Growth Hormone-Secreting Pituitary Adenoma - diagnostic imaging | Pituitary Function Tests | Humans | Middle Aged | Male | Growth Hormone-Secreting Pituitary Adenoma - diagnosis | Pituitary ACTH Hypersecretion - blood | Radiography | Acromegaly - complications | Diabetes Mellitus, Type 2 - blood | Growth Hormone-Secreting Pituitary Adenoma - surgery | Pituitary ACTH Hypersecretion - complications | Pituitary ACTH Hypersecretion - surgery | Acromegaly - surgery | Adenoma - diagnostic imaging | Human Growth Hormone - blood | Acromegaly - blood | Hydrocortisone - blood | Adrenocorticotropic Hormone - blood | Diabetes Mellitus, Type 2 - complications | Index Medicus
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12. Full Text Immunohistochemical analysis of 11-β-hydroxysteroid dehydrogenase type 2 and glucocorticoid receptor in subclinical cushing's disease due to pituitary macroadenoma
by Ebisawa, Takanori and Tojo, Katsuyoshi and Tajima, Naoko and Kamio, Masami and Oki, Yutaka and Ono, Katsuhiko and Sasano, Hironobu
Endocrine Pathology, ISSN 1046-3976, 12/2008, Volume 19, Issue 4, pp. 252 - 260
Subclinical Cushing's disease (SCD) is characterized by lack of clinically evident Cushingoid features, despite abnormal hypersecretion of ACTH. Nearly half... 
Immunohistochemistry | ACTH | 11β- hydroxysteroid dehydrogenase type 2 | Pituitary macroadenoma | Subclinical Cushing's disease | Glucocorticoid receptor | CELLS | glucocorticoid receptor | NELSONS-SYNDROME | DEXAMETHASONE | CORTICOTROPH MACROADENOMAS | pituitary macroadenoma | DEPENDENT HYPERADRENOCORTICISM | PATHOLOGY | SUPPRESSION | subclinical Cushing's disease | GENE | PROOPIOMELANOCORTIN | ENDOCRINOLOGY & METABOLISM | RESISTANCE | 11 beta-hydroxysteroid dehydrogenase type 2 | immunohistochemistry | ADENOMAS | Pituitary Gland - metabolism | Humans | Middle Aged | Male | Receptors, Glucocorticoid - metabolism | ACTH-Secreting Pituitary Adenoma - complications | Adenoma - metabolism | Young Adult | Adenoma - complications | Adult | Female | Adrenocorticotropic Hormone - metabolism | Pituitary ACTH Hypersecretion - pathology | Pituitary ACTH Hypersecretion - etiology | ACTH-Secreting Pituitary Adenoma - metabolism | Pituitary Gland - pathology | Acromegaly - metabolism | Immunohistochemistry - methods | Pituitary ACTH Hypersecretion - metabolism | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - metabolism | Adolescent | Adenoma - pathology | Aged | ACTH-Secreting Pituitary Adenoma - pathology | Acromegaly - pathology | Index Medicus
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13. Full Text Diagnostic performance of salivary cortisol and serum osteocalcin measurements in patients with overt and subclinical Cushing's syndrome
by Sereg, Márta and Tőke, Judit and Patócs, Attila and Varga, Ibolya and Igaz, Péter and Szücs, Nikolette and Horányi, János and Pusztai, Péter and Czirják, Sándor and Gláz, Edit and Rácz, Károly and Tóth, Miklós
Steroids, ISSN 0039-128X, 2011, Volume 76, Issue 1, pp. 38 - 42
▶ Automated electrochemiluminescence immunoassay for salivary cortisol measurements. ▶ Serum osteocalcin compared to other tests used for the diagnosis of... 
Serum osteocalcin | Subclinical Cushing's syndrome | Salivary cortisol | Bone markers | Cushing's disease | TESTS | DEXAMETHASONE | TURNOVER | LATE-NIGHT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MARKERS | HYPERCORTISOLISM | ADRENAL INCIDENTALOMA | DISEASE | ENDOCRINOLOGY & METABOLISM | BONE MASS | Immunoassay | Humans | Middle Aged | Cushing Syndrome - diagnosis | Male | Saliva - chemistry | Young Adult | Osteocalcin - blood | Adolescent | Hydrocortisone - analysis | Aged, 80 and over | Adult | Cushing Syndrome - blood | Female | Aged | Child | Corticosteroids | Diagnosis | Cushing syndrome | Steroids | Index Medicus
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14. Full Text Nur77 gene expression levels were involved in different ACTH-secretion autonomy between Cushing’s disease and subclinical Cushing’s disease
by Tabuchi, Yukiko and Kitamura, Tetsuhiro and Fukuhara, Atsunori and Mukai, Kosuke and Onodera, Toshiharu and Miyata, Yugo and Otsuki, Michio and Shimomura, Iichiro and Hamasaki, Toshimitsu and Oshino, Satoru and Saitoh, Youichi and Morii, Eiichi
Endocrine Journal, ISSN 0918-8959, 2016, Volume 63, Issue 6, pp. 545 - 554
Nur77 | Adrenocorticotropic hormone | Pro-opiomelanocortin | Cushing’s disease | Subclinical Cushing’s disease
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15. Full Text Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing’s disease: a case report
by Takiguchi, Tomoko and Koide, Hisashi and Nagano, Hidekazu and Nakayama, Akitoshi and Fujimoto, Masanori and Tamura, Ai and Komai, Eri and Shiga, Akina and Kono, Takashi and Higuchi, Seiichiro and Sakuma, Ikki and Hashimoto, Naoko and Suzuki, Sawako and Miyabayashi, Yui and Ishiwatari, Norio and Horiguchi, Kentaro and Nakatani, Yukio and Yokote, Koutaro and Tanaka, Tomoaki
BMC Endocrine Disorders, ISSN 1472-6823, 12/2017, Volume 17, Issue 1, pp. 1 - 8
Abstract Background A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) -producing adenomas (GHoma)... 
GHoma | Case report | Transcriptional factor | Pituitary adenoma | Subclinical Cushing’s disease
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16. Cushing's syndrome: special issues
by Goñi Iriarte, María José
Endocrinologia y Nutricion, ISSN 1575-0922, 2009, Volume 56, Issue 5, pp. 251 - 261
The present article reviews: Corticotrophin (ACTH) independent bilateral macronodular adrenal hyperplasia, which is characterized by aberrant adrenal receptors... 
Cushing's disease | Subclinical Cushing's syndrome | Cushing's syndrome | Bilateral macronodular adrenal hyperplasia
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17. Full Text Plurihormonal pituitary adenoma: Acromegaly associated with subclinical cushing’s disease
by Korkmaz, H and Akarsu, E and Özkaya, M and Öztürk, Z.A and Tutar, E and Araz, M
Acta Endocrinologica, ISSN 1841-0987, 07/2015, Volume 11, Issue 3, pp. 389 - 393
Acromegaly | Plurihormonal pituitary adenoma | Subclinical Cushing’s disease
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18. Full Text Treatment of skeletal impairment in patients with endogenous hypercortisolism: when and how?
by Scillitani, A and Mazziotti, G and Di Somma, C and Moretti, S and Stigliano, A and Pivonello, R and Giustina, A and Colao, A and ABC Grp and On behalf of ABC Group
Osteoporosis International, ISSN 0937-941X, 2/2014, Volume 25, Issue 2, pp. 441 - 446
Guidelines for the management of osteoporosis induced by endogenous hypercortisolism are not available. Both the American College of Rheumatology and the... 
Osteoporosis | Medicine & Public Health | Glucocorticoids | Cushing’s disease | Orthopedics | Rheumatology | Endocrinology | Adrenal incidentaloma | Cushing's disease | ADULT PATIENTS | GH DEFICIENCY | SUBCLINICAL HYPERCORTISOLISM | GLUCOCORTICOID-INDUCED OSTEOPOROSIS | CUSHINGS-SYNDROME | VERTEBRAL FRACTURES | DISEASE | GROWTH | ENDOCRINOLOGY & METABOLISM | REPLACEMENT THERAPY | BONE | Care and treatment | Fractures | Corticosteroids | Cushing syndrome | Diagnosis | Health aspects | Risk factors | Drug therapy | Steroids | Index Medicus
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19. Full Text Classification and surgical treatment for 180 cases of adrenocortical hyperplastic disease
by Zhang, Yushi and Li, Hanzhong
International Journal of Clinical and Experimental Medicine, ISSN 1940-5901, 10/2015, Volume 8, Issue 10, pp. 19311 - 19317
Objective: To review and discuss the diagnostic and surgical therapeutic methods of adrenocortical hyperplastic disease. Methods: A retrospective analysis was... 
Adrenalectomy | Diagnosis | Hyperaldosteronism | Cushing disease | Surgical treatment | Adrenocortical hyperplasia | PRIMARY HYPERALDOSTERONISM | MEDICINE, RESEARCH & EXPERIMENTAL | UNILATERAL ADRENAL-HYPERPLASIA | ACTH | diagnosis | surgical treatment | PRIMARY ALDOSTERONISM | adrenalectomy | hyperaldosteronism | UPDATE | SUBCLINICAL CUSHINGS-SYNDROME | cushing disease
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20. Full Text Subclinical Hypercortisolism in Hospitalized Patients with Type 2 Diabetes Mellitus
by TANIGUCHI, Takao and HAMASAKI, Akihiro and OKAMOTO, Motozumi
Endocrine Journal, ISSN 0918-8959, 2008, Volume 55, Issue 2, pp. 429 - 432
Pre(sub)clinical Cushing's disease is a recently described entity defined by the autonomous secretion of ACTH and the absence of a cushingoid appearance. We... 
Pre(sub)clinical Cushing's disease | Insulin sensitivity | Subclinical hypercortisolism | Diabetes mellitus | Glucose clamp study | insulin sensitivity | CUSHINGS-SYNDROME | DISEASE | ENDOCRINOLOGY & METABOLISM | diabetes mellitus | glucose clamp study | subclinical hypercortisolism | pre(sub)clinical Cushing's disease | CORTISOL | Index Medicus
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